Gemma Pelargonio
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View article: Risk Stratification and Optimal Use of Implantable Cardioverter-Defibrillator Therapy in Primary Prevention of Sudden Cardiac Death in Genetic Cardiomyopathies, with Assessment of the Role of Genetic Variants in Guiding Therapeutic Decisions
Risk Stratification and Optimal Use of Implantable Cardioverter-Defibrillator Therapy in Primary Prevention of Sudden Cardiac Death in Genetic Cardiomyopathies, with Assessment of the Role of Genetic Variants in Guiding Therapeutic Decisions Open
Genetic background is a critical determinant of disease expression, arrhythmic vulnerability, and therapeutic response in inherited cardiomyopathies. Implantable cardioverter-defibrillators (ICD) remain the cornerstone for primary preventi…
View article: Cryptogenic stroke, left atrial function, and atrial fibrillation: a complex relationship
Cryptogenic stroke, left atrial function, and atrial fibrillation: a complex relationship Open
Background Paroxysmal atrial fibrillation (AF) may underlie some embolic strokes of undetermined source (ESUS), but the widespread use of loop recorders (LRs) to detect it may not be cost-effective. This study evaluated whether assessing l…
View article: Atrial Strain Analysis Predicts Atrial Arrhythmia Recurrence Following Cavotricuspid Isthmus Ablation of Typical Atrial Flutter
Atrial Strain Analysis Predicts Atrial Arrhythmia Recurrence Following Cavotricuspid Isthmus Ablation of Typical Atrial Flutter Open
Background: This study aimed to evaluate the effectiveness of right and left atrial strain reservoir (RASr and LASr) in predicting the recurrence of atrial arrhythmias (AAs) following cavotricuspid isthmus ablation (CTIA) for typical atria…
View article: Right atrial strain in atrial fibrillation: the hidden side of the moon
Right atrial strain in atrial fibrillation: the hidden side of the moon Open
Introduction Left atrial (LA) remodeling in atrial fibrillation (AF) is well studied, whereas right atrial (RA) alterations remain poorly characterized. This study evaluates bi-atrial strain dynamics in patients with AF undergoing catheter…
View article: The Diagnostic and Prognostic Value of the 12-Lead ECG in Arrhythmogenic Left Ventricular Cardiomyopathy
The Diagnostic and Prognostic Value of the 12-Lead ECG in Arrhythmogenic Left Ventricular Cardiomyopathy Open
View article: Procedural workflow and long-term outcomes of pulsed-field ablation as a repeat procedure in comparison with conventional radiofrequency ablation in patients with paroxysmal atrial fibrillation
Procedural workflow and long-term outcomes of pulsed-field ablation as a repeat procedure in comparison with conventional radiofrequency ablation in patients with paroxysmal atrial fibrillation Open
Background Repeated procedures are often needed for long-term success of atrial fibrillation (AF) ablation. There are scarce data regarding electroporation by means of pulsed-field ablation (PFA) use for such procedure. Purpose We analyzed…
View article: Concordance and reliability between electroanatomical mapping using high density mapping catheter and ADAS-3D software for myocardial tissue characterization in non-ischemic cardiomyopathy patients
Concordance and reliability between electroanatomical mapping using high density mapping catheter and ADAS-3D software for myocardial tissue characterization in non-ischemic cardiomyopathy patients Open
Introduction Risk assessment for ventricular arrhythmias (VAs) and sudden cardiac death (SCD) in non-ischemic cardiomyopathy (NICM) is a clinical challenge. Late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) is the gold stand…
View article: Ventricular substrate characteristics using omnipolar technology-derived vector disarray and peak frequency
Ventricular substrate characteristics using omnipolar technology-derived vector disarray and peak frequency Open
Background Three-dimensional electroanatomic mapping and ablation of ventricular tachycardias (VT) is a complex process that integrates data from multiple procedural steps, including substrate and activation mapping. Purpose To streamline …
View article: Arrhythmic mitral valve Prolapse (MIVAP) Predict Protocol: preliminary results
Arrhythmic mitral valve Prolapse (MIVAP) Predict Protocol: preliminary results Open
Background and Aim Mitral valve prolapse (MVP) is a common valve disease affecting 0.6-3.1% of the general population, occasionally leading to severe complications, including malignant ventricular arrhythmias and sudden cardiac death as th…
View article: Long-term risk assessment in athletes with complex ventricular arrhythmias
Long-term risk assessment in athletes with complex ventricular arrhythmias Open
Background Ventricular arrhythmias (VAs) are a major concern in athletes. We sought to determine the prognostic role of non-invasive and invasive assessments in athletes with complex VAs. Methods Two-hundred-fifteen athletes (83% male; 28 …
View article: Focal lattice tip catheter toggling between pulsed field energy and radiofrequency vs. high power short duration for pulmonary vein isolation: a multicenter study
Focal lattice tip catheter toggling between pulsed field energy and radiofrequency vs. high power short duration for pulmonary vein isolation: a multicenter study Open
Introduction A novel focal 9mm lattice tip catheter, namely Sphere-9 (Affera Inc), has recently received regulatory approval and is part of a technology that allows the delivery of either pulsed electric field or radiofrequency energy and …
View article: New peak frequency maps' usefulness to enhance localization and ablation of premature ventricular contractions
New peak frequency maps' usefulness to enhance localization and ablation of premature ventricular contractions Open
Background Premature ventricular contractions (PVCs) are a common type of idiopathic ventricular arrhythmia. Catheter ablation has emerged as a first-line therapy with a high success rate and few complications. Traditional ablation targets…
View article: Leadless pacemaker implantation in real‐world clinical practice: An Italian survey promoted by the <scp>AIAC</scp> (Italian Association of Arrhythmology and Cardiac Pacing)
Leadless pacemaker implantation in real‐world clinical practice: An Italian survey promoted by the <span>AIAC</span> (Italian Association of Arrhythmology and Cardiac Pacing) Open
Backgrounds After a decade since the introduction of leadless pacemaker (L‐PM), its use is still limited. The aim of this survey is to evaluate how this technology is perceived by electrophysiologist members of a National scientific societ…
View article: Women in Interventional Cardiology: A Survey of Radiation Exposure and Breast Cancer Occurrence
Women in Interventional Cardiology: A Survey of Radiation Exposure and Breast Cancer Occurrence Open
Background and Aims: Breast cancer (BC) is the leading cause of cancer in women. Female interventional cardiologists are potentially at a higher risk of developing BC due to occupational radiation exposure. This survey aimed at understandi…
View article: Ultrasound‐Guided Axillary Vein Puncture Versus Landmark‐Guided Approach for Cardiac Implantable Electronic Device Placement
Ultrasound‐Guided Axillary Vein Puncture Versus Landmark‐Guided Approach for Cardiac Implantable Electronic Device Placement Open
Introduction Ultrasound (US)‐guided axillary vein puncture is a safe and effective approach for cardiac implantable electronic device (CIED) implantation, and it is highly recommended by the current consensus document. However, only report…
View article: Characteristics and Outcome of Patients with or without Previous Implantable Cardioverter Defibrillator Interventions Undergoing Ablation for Ventricular Tachycardia
Characteristics and Outcome of Patients with or without Previous Implantable Cardioverter Defibrillator Interventions Undergoing Ablation for Ventricular Tachycardia Open
Background: Catheter ablation (CA) is a well-established treatment in patients with ventricular tachycardia and appropriate implantable cardioverter defibrillator (ICD) therapies. Methods: We enrolled 57 consecutive carriers of ICD undergo…
View article: Atrial High-Rate Episodes and Subclinical Atrial Fibrillation: State of the Art and Clinical Questions with Complex Solutions
Atrial High-Rate Episodes and Subclinical Atrial Fibrillation: State of the Art and Clinical Questions with Complex Solutions Open
Atrial high-rate episodes (AHREs) and subclinical atrial fibrillation (AF) are frequently registered in asymptomatic patients with cardiac implantable electronic devices (CIEDs) and insertable cardiac monitors (ICMs). While an increased ri…
View article: Editorial: Cardiopulmonary support during catheter ablation of ventricular arrhythmias with hemodynamic instability
Editorial: Cardiopulmonary support during catheter ablation of ventricular arrhythmias with hemodynamic instability Open
Editorial: Cardiopulmonary support during catheter ablation of ventricular arrhythmias with hemodynamic instability
View article: Remote Monitoring of Cardiac Implantable Electronic Devices in Very Elderly Patients: Advantages and Specific Problems
Remote Monitoring of Cardiac Implantable Electronic Devices in Very Elderly Patients: Advantages and Specific Problems Open
Cardiac implantable electronic devices (CIEDs) offer the benefit of remote monitoring and decision making and find particular applications in special populations such as the elderly. Less transportation, reduced costs, prompt diagnosis, a …
View article: Closed loop stimulation reduces the incidence of atrial high-rate episodes compared with conventional rate-adaptive pacing in patients with sinus node dysfunctions
Closed loop stimulation reduces the incidence of atrial high-rate episodes compared with conventional rate-adaptive pacing in patients with sinus node dysfunctions Open
Aims Subclinical atrial fibrillation (AF) is associated with increased risk of progression to clinical AF, stroke, and cardiovascular death. We hypothesized that in pacemaker patients requiring dual-chamber rate-adaptive (DDDR) pacing, clo…
View article: Anatomical Annulus Predictors of New Permanent Pacemaker Implantation Risk After Balloon-Expandable Transcatheter Aortic Valve Implantation
Anatomical Annulus Predictors of New Permanent Pacemaker Implantation Risk After Balloon-Expandable Transcatheter Aortic Valve Implantation Open
New-generation transcatheter heart valves have significantly improved technical success and procedural safety of transcatheter aortic valve implantation (TAVI) procedures; however, the incidence of permanent pacemaker implantation (PPI) re…
View article: Italian Registry in the Setting of Atrial Fibrillation Ablation with Rivaroxaban - IRIS
Italian Registry in the Setting of Atrial Fibrillation Ablation with Rivaroxaban - IRIS Open
IRIS is the biggest real-life data registry regarding CA ablation on rivaroxaban in Italian setting, proving the safety and efficacy of rivaroxaban.
View article: Chronic inflammatory cardiomyopathy and its overlap with arrhythmogenic cardiomyopathy: long-term follow-up of a prospective single-centre cohort study
Chronic inflammatory cardiomyopathy and its overlap with arrhythmogenic cardiomyopathy: long-term follow-up of a prospective single-centre cohort study Open
Background Chronic Inflammatory Cardiomyopathy (infl-CMP) may overlap with Arrhythmogenic Cardiomyopathy (ACM), a group of conditions with similar ventricular arrhythmic phenotypes and key imaging, electrocardiographic, histopathological, …
View article: Long-term risk assessment in athletes with ventricular arrhythmias: the key roles of arrhythmia morphology, complexity, and substrate
Long-term risk assessment in athletes with ventricular arrhythmias: the key roles of arrhythmia morphology, complexity, and substrate Open
Background Ventricular arrhythmias (VAs) are an important source of concern among athletes. Purpose To determine the prognostic role of non-invasive and invasive diagnostic assessments among athletes with complex VAs. Methods We included 2…
View article: Ultra-high density mapping and ablation of localized microreentrant tachycardias: insight from the CHARISMA registry
Ultra-high density mapping and ablation of localized microreentrant tachycardias: insight from the CHARISMA registry Open
Background The optimal criteria for distinguishing microreentrant atrial tachycardias (mAT) from macroreentrant atrial arrhythmias (MAT) in clinical practice have not been definitively established. Recent advancements in ultra-high-density…
View article: Arrhythmic mitral valve prolapse with versus without prior mitral valve repair: clinical profiles, electrophysiological substrates, and long-term clinical outcomes
Arrhythmic mitral valve prolapse with versus without prior mitral valve repair: clinical profiles, electrophysiological substrates, and long-term clinical outcomes Open
Background Arrhythmic mitral valve prolapse (AMVP) is characterized by an arrhythmogenic left ventricular substrate, with high prevalence of myocardial scar. Whether patients with prior mitral valve repair for mitral valve prolapse (MVP) a…
View article: Right Atrial Strain in Atrial Fibrillation: The Hidden Side of the Moon
Right Atrial Strain in Atrial Fibrillation: The Hidden Side of the Moon Open
View article: Major Adverse Cardiovascular Events and Arrhythmic Risk in Patients with Spontaneous Coronary Artery Dissection: The Need for Long-Term Follow-Up
Major Adverse Cardiovascular Events and Arrhythmic Risk in Patients with Spontaneous Coronary Artery Dissection: The Need for Long-Term Follow-Up Open
View article: Pulmonary vein isolation by means of a novel cryoballoon technology in paroxysmal atrial fibrillation patients: 1‐year outcome from a large Italian multicenter clinical registry
Pulmonary vein isolation by means of a novel cryoballoon technology in paroxysmal atrial fibrillation patients: 1‐year outcome from a large Italian multicenter clinical registry Open
Introduction Recently, a new cryoballoon (CB) technology (POLARx; Boston Scientific) has come onto the market. Preliminary data have shown that its acute safety and efficacy are similar to those of the first‐generation CB. The aim of this …
View article: Reply by Casella et al to Letter Regarding Article, “Incidence of ventricular arrhythmias related to Covid infection and vaccination in patients with Brugada syndrome: Insights from a large Italian multicenter registry based on continuous rhythm monitoring”
Reply by Casella et al to Letter Regarding Article, “Incidence of ventricular arrhythmias related to Covid infection and vaccination in patients with Brugada syndrome: Insights from a large Italian multicenter registry based on continuous rhythm monitoring” Open