Geneva E. Cruz
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View article: Blocking Ccn2 Reduces Established Losses in Bone Volume Induced by Prolonged Intense Loading by Increasing Osteoblast Activity and Trabecular Thickness
Blocking Ccn2 Reduces Established Losses in Bone Volume Induced by Prolonged Intense Loading by Increasing Osteoblast Activity and Trabecular Thickness Open
View article: Manual Therapy With Rest as a Treatment for Established Inflammation and Fibrosis in a Rat Model of Repetitive Strain Injury
Manual Therapy With Rest as a Treatment for Established Inflammation and Fibrosis in a Rat Model of Repetitive Strain Injury Open
Background : Repetitive strain injuries caused by repetitive occupational work are difficult to prevent for multiple reasons. Therefore, we examined the effectiveness of manual therapy (MT) with rest to treat the inflammation and fibrosis …
View article: MP08-11 ENHANCED NEUROGENIC ACTIVITY AND NERVE DENSITY IN SMOOTH MUSCLE STRIPS TAKEN FROM CLOSER TO THE SEROSAL SIDE OF THE HUMAN AND DOG BLADDER
MP08-11 ENHANCED NEUROGENIC ACTIVITY AND NERVE DENSITY IN SMOOTH MUSCLE STRIPS TAKEN FROM CLOSER TO THE SEROSAL SIDE OF THE HUMAN AND DOG BLADDER Open
You have accessJournal of UrologyBladder & Urethra: Anatomy, Physiology & Pharmacology (MP08)1 Sep 2021MP08-11 ENHANCED NEUROGENIC ACTIVITY AND NERVE DENSITY IN SMOOTH MUSCLE STRIPS TAKEN FROM CLOSER TO THE SEROSAL SIDE OF THE HUMAN AND DO…
View article: MP08-09 NERVE TRANSFER FOR RESTORATION OF LOWER MOTOR NEURON-LESIONED BLADDER FUNCTION. CORRELATION BETWEEN HISTOLOGICAL CHANGES AND NERVE EVOKED CONTRACTIONS
MP08-09 NERVE TRANSFER FOR RESTORATION OF LOWER MOTOR NEURON-LESIONED BLADDER FUNCTION. CORRELATION BETWEEN HISTOLOGICAL CHANGES AND NERVE EVOKED CONTRACTIONS Open
You have accessJournal of UrologyBladder & Urethra: Anatomy, Physiology & Pharmacology (MP08)1 Sep 2021MP08-09 NERVE TRANSFER FOR RESTORATION OF LOWER MOTOR NEURON-LESIONED BLADDER FUNCTION. CORRELATION BETWEEN HISTOLOGICAL CHANGES AND NER…
View article: PD36-03 RESTORATION OF BLADDER, URETHRAL AND ANAL SPHINCTER FUNCTION AFTER SURGICAL REINNERVATION IN LOWER MOTOR NEURON LESIONED CANINES
PD36-03 RESTORATION OF BLADDER, URETHRAL AND ANAL SPHINCTER FUNCTION AFTER SURGICAL REINNERVATION IN LOWER MOTOR NEURON LESIONED CANINES Open
You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Neurogenic Voiding Dysfunction (PD36)1 Sep 2021PD36-03 RESTORATION OF BLADDER, URETHRAL AND ANAL SPHINCTER FUNCTION AFTER SURGICAL REINNER…
View article: Key indicators of repetitive overuse-induced neuromuscular inflammation and fibrosis are prevented by manual therapy in a rat model
Key indicators of repetitive overuse-induced neuromuscular inflammation and fibrosis are prevented by manual therapy in a rat model Open
View article: Nerve transfer for restoration of lower motor neuron-lesioned bladder function. Part 2: correlation between histological changes and nerve evoked contractions
Nerve transfer for restoration of lower motor neuron-lesioned bladder function. Part 2: correlation between histological changes and nerve evoked contractions Open
We determined the effect of pelvic organ decentralization and reinnervation 1 yr later on urinary bladder histology and function. Nineteen canines underwent decentralization by bilateral transection of all coccygeal and sacral (S) spinal r…
View article: Issue Information ‐ Editorial Board and TOC
Issue Information ‐ Editorial Board and TOC Open
View article: Blocking CTGF/CCN2 reverses neural fibrosis and sensorimotor declines in a rat model of overuse‐induced median mononeuropathy
Blocking CTGF/CCN2 reverses neural fibrosis and sensorimotor declines in a rat model of overuse‐induced median mononeuropathy Open
Encapsulation of median nerves is a hallmark of overuse‐induced median mononeuropathy and contributes to functional declines. We tested if an antibody against CTGF/CCN2 (termed FG‐3019 or Pamrevlumab) reduces established neural fibrosis an…
View article: Blocking CTGF/CCN2 reduces established skeletal muscle fibrosis in a rat model of overuse injury
Blocking CTGF/CCN2 reduces established skeletal muscle fibrosis in a rat model of overuse injury Open
Tissue fibrosis is a hallmark of overuse musculoskeletal injuries and contributes to functional declines. We tested whether inhibition of CCN2 (cellular communication network factor 2, previously known as connective tissue growth factor, C…
View article: Forced treadmill running reduces systemic inflammation yet worsens upper limb discomfort in a rat model of work-related musculoskeletal disorders
Forced treadmill running reduces systemic inflammation yet worsens upper limb discomfort in a rat model of work-related musculoskeletal disorders Open
View article: Forced Treadmill Running Reduces Systemic Inflammation Yet Worsens Upper Limb Discomfort in a rat model of Work-Related Musculoskeletal Disorders
Forced Treadmill Running Reduces Systemic Inflammation Yet Worsens Upper Limb Discomfort in a rat model of Work-Related Musculoskeletal Disorders Open
Background: Musculoskeletal disorders can result from prolonged repetitive and/or forceful movements. Performance of an upper extremity high repetition high force task increases serum pro-inflammatory cytokines and upper extremity sensorim…
View article: Forced Treadmill Running Reduces Systemic Inflammation Yet Worsens Upper Limb Discomfort in a rat model of Work-Related Musculoskeletal Disorders
Forced Treadmill Running Reduces Systemic Inflammation Yet Worsens Upper Limb Discomfort in a rat model of Work-Related Musculoskeletal Disorders Open
Background: Musculoskeletal disorders can result from prolonged repetitive and/or forceful movements. Performance of an upper extremity high repetition high force task increases serum pro-inflammatory cytokines and upper extremity sensorim…
View article: Bladder reinnervation by somatic nerve transfer to pelvic nerve vesical branches does not reinnervate the urethra
Bladder reinnervation by somatic nerve transfer to pelvic nerve vesical branches does not reinnervate the urethra Open
Aims We sought to determine whether somatic lumbar nerve transfer to the pelvic nerve's anterior vesical branch after sacral decentralization for detrusor muscle reinnervation also leads to aberrant innervation of the bladder outlet. Metho…
View article: Nerve transfer for restoration of lower motor neuron–lesioned bladder and urethra function: establishment of a canine model and interim pilot study results
Nerve transfer for restoration of lower motor neuron–lesioned bladder and urethra function: establishment of a canine model and interim pilot study results Open
OBJECTIVE Previous patient surveys have shown that patients with spinal cord or cauda equina injuries prioritize recovery of bladder function. The authors sought to determine if nerve transfer after long-term decentralization restores blad…
View article: Blocking substance P signaling reduces musculotendinous and dermal fibrosis and sensorimotor declines in a rat model of overuse injury
Blocking substance P signaling reduces musculotendinous and dermal fibrosis and sensorimotor declines in a rat model of overuse injury Open
Purpose/Aim: Substance P-NK-1R signaling has been implicated in fibrotic tendinopathies and myositis. Blocking this signaling with a neurokinin 1 receptor antagonist (NK1RA) has been proposed as a therapeutic target for their treatm…
View article: The answer depends on the question: Optimal conditions for western blot characterization of muscle collagen type 1 depends on desired isoform
The answer depends on the question: Optimal conditions for western blot characterization of muscle collagen type 1 depends on desired isoform Open
Fibrillar collagen type 1 is the most abundant type of collagen within the body and is a critical component of extracellular infrastructure. In order to assess collagen synthesis and extracellular accumulation in fibrotic disorders, improv…
View article: Blocking CCN2 Reduces Progression of Sensorimotor Declines and Fibrosis in a Rat Model of Chronic Repetitive Overuse
Blocking CCN2 Reduces Progression of Sensorimotor Declines and Fibrosis in a Rat Model of Chronic Repetitive Overuse Open
Fibrosis may be a key factor in sensorimotor dysfunction in patients with chronic overuse‐induced musculoskeletal disorders. Using a clinically relevant rodent model, in which performance of a high demand handle‐pulling task induces tissue…
View article: Blocking substance P signaling reduces musculotendinous and dermal fibrosis and sensorimotor declines in a rat model of overuse injury
Blocking substance P signaling reduces musculotendinous and dermal fibrosis and sensorimotor declines in a rat model of overuse injury Open
Purpose/Aim: Substance P-NK-1R signaling has been implicated in fibrotic tendinopathies and myositis. Blocking this signaling with a neurokinin 1 receptor antagonist (NK1RA) has been proposed as a therapeutic target for their treatm…