Gennaro Giustino
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View article: Utility of High‐Sensitivity Cardiac Troponin‐T and N‐Terminal Pro‐B‐Type Natriuretic Peptide to Predict Survival, Quality of Life, and Functional Status Changes After Transcatheter Aortic Valve Implantation
Utility of High‐Sensitivity Cardiac Troponin‐T and N‐Terminal Pro‐B‐Type Natriuretic Peptide to Predict Survival, Quality of Life, and Functional Status Changes After Transcatheter Aortic Valve Implantation Open
Background Cardiac biomarkers are minimally incorporated into current aortic valve guidelines, except for elevated BNP (B‐type natriuretic peptide) in asymptomatic severe aortic stenosis. This prospective observational cohort studied how p…
View article: The Emerging Role of Lithotripsy in Structural Heart Interventions
The Emerging Role of Lithotripsy in Structural Heart Interventions Open
We have conducted a comprehensive literature review of all publications on lithotripsy in structural heart interventions found in PubMed and Google Scholar. We have also included a series of case examples of lithotripsy in structural heart…
View article: Transfemoral Retrograde Transcatheter Mechanical Thrombectomy of Massive Left Ventricular Thrombus
Transfemoral Retrograde Transcatheter Mechanical Thrombectomy of Massive Left Ventricular Thrombus Open
Transcatheter thrombectomy is a safe alternative for patients with left-sided intracardiac masses who are at high risk for surgery. Trans-septal or retrograde transaortic approaches may be used for mass extraction.
View article: Transseptal Access Through Prior Atrial Septal Occluder Device for TMVR for Prosthetic Mitral Valve Degeneration
Transseptal Access Through Prior Atrial Septal Occluder Device for TMVR for Prosthetic Mitral Valve Degeneration Open
Transseptal access through a Cardioform Septal Occluder is feasible for valve-in-valve TMVR. Awareness of strategies to manage prior interatrial septum closures is crucial as repeat mitral interventions become more common.
View article: Acute Valve Syndrome Before Aortic Valve Replacement: Impact on Clinical Outcomes, Health Care Costs, and Resource Use
Acute Valve Syndrome Before Aortic Valve Replacement: Impact on Clinical Outcomes, Health Care Costs, and Resource Use Open
Background A classification system describing clinical presentation before aortic valve replacement (AVR) has recently been proposed (stable valve syndrome [SVS]), mildly symptomatic (progressive valve syndrome), or with acute and severe s…
View article: Retrograde Balloon-Induced Anterior Mitral Leaflet Laceration: The ROBIN Technique
Retrograde Balloon-Induced Anterior Mitral Leaflet Laceration: The ROBIN Technique Open
View article: Balloon-Assisted Leaflet Laceration to Prevent Coronary Obstruction During TAVR
Balloon-Assisted Leaflet Laceration to Prevent Coronary Obstruction During TAVR Open
Modified UNICORN is a viable alternative strategy to prevent CO during high-risk TAVR. Further data are needed to define its efficacy and safety.
View article: Feasibility, Efficacy, and Safety of the Mitral Annulo-TRIpsy in eXtreme Risk Patients
Feasibility, Efficacy, and Safety of the Mitral Annulo-TRIpsy in eXtreme Risk Patients Open
View article: 71729 | Feasibility and Safety of the Mitral Annulo-Tripsy in Extreme Risk Patients (MATRIX) With Severe Calcific Mitral Valve Stenosis
71729 | Feasibility and Safety of the Mitral Annulo-Tripsy in Extreme Risk Patients (MATRIX) With Severe Calcific Mitral Valve Stenosis Open
View article: 72160 | Left Atrial Veno-Arterial ECMO (LAVA-ECMO) in Cardiogenic Shock as a Bridge to Surgical or Transcatheter Therapies: A Single-Center Experience
72160 | Left Atrial Veno-Arterial ECMO (LAVA-ECMO) in Cardiogenic Shock as a Bridge to Surgical or Transcatheter Therapies: A Single-Center Experience Open
View article: Aortic Valve Stenosis and Calcified Abdominal Aortic Stenosis Treated With Lithotripsy-Facilitated TAVR and Aortic Stenting
Aortic Valve Stenosis and Calcified Abdominal Aortic Stenosis Treated With Lithotripsy-Facilitated TAVR and Aortic Stenting Open
View article: 72165 | Balloon-Assisted Leaflet Modification With the UNICORN Technique to Prevent Iatrogenic Coronary Artery Obstruction in High-Risk TAVR: A Single-Center Experience
72165 | Balloon-Assisted Leaflet Modification With the UNICORN Technique to Prevent Iatrogenic Coronary Artery Obstruction in High-Risk TAVR: A Single-Center Experience Open
View article: 72163 | Developing a Leaflet Modification Program to Optimize Transcatheter Valve Therapies: A Single-Center Experience
72163 | Developing a Leaflet Modification Program to Optimize Transcatheter Valve Therapies: A Single-Center Experience Open
View article: Use of lithotripsy (IVL) in severe calcified homograft for optimizing Transcatheter Pulmonary Valve Replacement (TPVR)
Use of lithotripsy (IVL) in severe calcified homograft for optimizing Transcatheter Pulmonary Valve Replacement (TPVR) Open
View article: First-in-Human Percutaneous Transseptal Retrieval of Embolized Transcatheter Valve in the Left Ventricle
First-in-Human Percutaneous Transseptal Retrieval of Embolized Transcatheter Valve in the Left Ventricle Open
View article: Aortic Valve Replacement in Asymptomatic Severe Aortic Stenosis: A Systematic Review and Meta-Analysis
Aortic Valve Replacement in Asymptomatic Severe Aortic Stenosis: A Systematic Review and Meta-Analysis Open
Data from observational studies and recent RCTs suggest that a strategy of preemptive AVR is associated with improved survival and lower rates of unplanned cardiovascular or HF-related hospitalizations and stroke compared to CS.
View article: Left Atrial Veno-Arterial Extracorporeal Membrane Oxygenation In Valvular Cardiogenic Shock
Left Atrial Veno-Arterial Extracorporeal Membrane Oxygenation In Valvular Cardiogenic Shock Open
View article: Lacerate and Macerate: The BASILICA–LLAMACORN/UNICORN Combination to Optimize Bioprosthetic Bileaflet Modification
Lacerate and Macerate: The BASILICA–LLAMACORN/UNICORN Combination to Optimize Bioprosthetic Bileaflet Modification Open
View article: Single-Access Technique for Impella-Assisted Balloon Aortic Valvuloplasty and High-Risk PCI in Cardiogenic Shock
Single-Access Technique for Impella-Assisted Balloon Aortic Valvuloplasty and High-Risk PCI in Cardiogenic Shock Open
The single-access technique for Impella-assisted high-risk percutaneous coronary intervention has been previously described and is frequently used in clinical practice to avoid a secondary arterial access and potentially reduce the risk of…
View article: Left atrial veno-arterial extracorporeal membrane oxygenation as a bridge to surgical or percutaneous closure of post-myocardial infarction ventriculoseptal defects: a case series
Left atrial veno-arterial extracorporeal membrane oxygenation as a bridge to surgical or percutaneous closure of post-myocardial infarction ventriculoseptal defects: a case series Open
Background Post-myocardial infarct (MI) ventricular septal defect (VSD) is a rare and severe complication of an acute MI with high mortality rate. The use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) as a bridge to surgic…
View article: Percutaneous Paravalvular Leak Closure of the EVOQUE Transcatheter Tricuspid Valve Replacement System
Percutaneous Paravalvular Leak Closure of the EVOQUE Transcatheter Tricuspid Valve Replacement System Open
•Transcatheter closure of paravalvular leak of the EVOQUE valve is feasible and can be done from a transfemoral or transjugular approach.•Preoperative cardiac computed tomography is useful to characterize the location and size of the parav…
View article: Subaortic Membrane and Cardiac Catheterization—Beware of Diagnostic Pitfall
Subaortic Membrane and Cardiac Catheterization—Beware of Diagnostic Pitfall Open
View article: Acute Valve Syndrome in Aortic Stenosis
Acute Valve Syndrome in Aortic Stenosis Open
View article: LAVA-ECMO–Supported Dual-Transcatheter Aortic and Mitral Valve-in-Valve Replacement in Cardiogenic Shock
LAVA-ECMO–Supported Dual-Transcatheter Aortic and Mitral Valve-in-Valve Replacement in Cardiogenic Shock Open
View article: Transcatheter Aortic Valve Replacement is Ready for Most Low-risk Patients: A Systematic Review of the Literature
Transcatheter Aortic Valve Replacement is Ready for Most Low-risk Patients: A Systematic Review of the Literature Open
Transcatheter aortic valve replacement (TAVR) has undergone rapid expansion, emerging as a viable therapeutic option for low-risk patients in lieu of surgical aortic valve replacement. This paper aims to provide a review of the scientific …
View article: Change in left ventricular function and outcomes following high-risk percutaneous coronary intervention with Impella-guided hemodynamic support
Change in left ventricular function and outcomes following high-risk percutaneous coronary intervention with Impella-guided hemodynamic support Open
Introduction High-risk percutaneous coronary interventions (HRPCI) are a potential treatment option for patients with reduced left ventricular ejection fraction (LVEF) and coronary artery disease. The extent to which such intervention is c…
View article: Antithrombotic Therapy in Patients Undergoing Transcatheter Aortic Valve Implantation
Antithrombotic Therapy in Patients Undergoing Transcatheter Aortic Valve Implantation Open
Transcatheter aortic valve implantation (TAVI) now represents the mainstay of treatment for severe aortic stenosis. Owing to its exceptional procedural efficacy and safety, TAVI has been extended to include patients at lower surgical risk,…
View article: Outcomes Following Percutaneous Coronary Intervention in Patients With Multivessel Disease Who Were Recommended for But Declined Coronary Artery Bypass Graft Surgery
Outcomes Following Percutaneous Coronary Intervention in Patients With Multivessel Disease Who Were Recommended for But Declined Coronary Artery Bypass Graft Surgery Open
Background Patients may prefer percutaneous coronary intervention (PCI) over coronary artery bypass graft (CABG) surgery, despite heart team recommendations. The outcomes in such patients have not been examined. We sought to examine the re…
View article: Antithrombotic Therapy in Patients Undergoing Transcatheter Aortic Valve Implantation
Antithrombotic Therapy in Patients Undergoing Transcatheter Aortic Valve Implantation Open
Transcatheter Aortic Valve Implantation (TAVI) now represents the mainstay in the treatment of severe aortic stenosis. Owing to its exceptional procedural efficacy and safety, TAVI has been extended to include patients at lower surgical ri…
View article: OR3-7 | High-Sensitivity Cardiac Troponin-T as a Prognostic Indicator of Mortality and Functional Status in Transcatheter Aortic Valve Replacement for Severe Aortic Stenosis
OR3-7 | High-Sensitivity Cardiac Troponin-T as a Prognostic Indicator of Mortality and Functional Status in Transcatheter Aortic Valve Replacement for Severe Aortic Stenosis Open
High-sensitivity cardiac troponin-T (hs-cTnT) is a cardiac biomarker primarily utilized in the diagnosis and risk-stratification of patients with acute coronary syndrome. Its role in patients undergoing TAVR is less well studied. This is a…