Gordon G. Wallace
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View article: Implantable drug delivery system improves tolerability of anti-CD40/anti-PD1 and chemotherapy in a murine model of breast cancer
Implantable drug delivery system improves tolerability of anti-CD40/anti-PD1 and chemotherapy in a murine model of breast cancer Open
Triple negative breast cancer (TNBC) is associated with the poorest prognosis among breast cancer subtypes and while immunotherapy has demonstrated some promise, its effectiveness as a monotherapy remains limited, offering only modest impr…
View article: Mechanobiologically-optimized non-resorbable artificial bone for patient-matched scaffold-guided bone regeneration
Mechanobiologically-optimized non-resorbable artificial bone for patient-matched scaffold-guided bone regeneration Open
Scaffold-guided bone regeneration is poised to revolutionize the management of critical-sized bone defects. However, translation into clinical practice has been hampered by the focus on bioresorbable scaffolds where the rate of degradation…
View article: 3D Printing Strategies for Bioengineering Human Cornea
3D Printing Strategies for Bioengineering Human Cornea Open
Over 4.2 million people worldwide suffer from vision impairment related to corneal diseases, with the shortage of donor corneas limiting surgical interventions. The development of 3D printing provides a promising solution for corneal tissu…
View article: Future Frontiers in Bioinspired Implanted Biomaterials
Future Frontiers in Bioinspired Implanted Biomaterials Open
Bioinspired materials draw design inspiration from nature's principles and integrate them with engineering requirements to construct highly functional and complex systems across multiple length scales. Bioinspired implanted biomaterials ar…
View article: Cathodic Exfoliation of Various Graphite Materials in Potassium Chloride Electrolyte
Cathodic Exfoliation of Various Graphite Materials in Potassium Chloride Electrolyte Open
Cathodic exfoliation of graphite has emerged as an attractive method to synthesize high-quality and lo- defect graphene. Here, it is demonstrated that the type of starting graphite material influences the properties of exfoliated graphene.…
View article: 3D Printing of Conducting Polymer Hydrogels for Electrostimulation‐Assisted Tissue Engineering
3D Printing of Conducting Polymer Hydrogels for Electrostimulation‐Assisted Tissue Engineering Open
Electrostimulation (ES) is at the cutting edge of contemporary medicine, effectively promoting tissue regeneration and wound healing by applying small electrical cues to stimulate specific cellular responses. The 3D printing of electronica…
View article: Tumor microenvironment–activated Zn//MnO <sub>2</sub> battery for sustained and local electrochemical immunotherapy
Tumor microenvironment–activated Zn//MnO <sub>2</sub> battery for sustained and local electrochemical immunotherapy Open
Metal ions are widely adopted to potentiate oxidative damage-induced immunogenic cell death (ICD) and regulate immune pathways. However, current ion delivery platforms lack precise administration over distribution and retention time within…
View article: Traffic Light Coding System for Engaging With <scp>AI</scp> in Surgery
Traffic Light Coding System for Engaging With <span>AI</span> in Surgery Open
Artificial Intelligence (AI) is generally defined as the development of computer systems or machines that can perform tasks typically requiring human intelligence and is increasingly being used in modern healthcare. While, various AI syste…
View article: Three-dimensional bioprinted in vitro glioma tumor constructs for synchrotron microbeam radiotherapy dosimetry and biological study using gelatin methacryloyl hydrogel
Three-dimensional bioprinted in vitro glioma tumor constructs for synchrotron microbeam radiotherapy dosimetry and biological study using gelatin methacryloyl hydrogel Open
Synchrotron microbeam radiotherapy (MRT) is an innovative cancer treatment that uses micron-sized of ultra-high dose rate spatially fractionated X-rays to effectively control cancer growth while reducing the damage to surrounding healthy t…
View article: Mechanobiologically-optimized non-resorbable artificial bone – a new paradigm in patient-matched scaffold-guided bone regeneration
Mechanobiologically-optimized non-resorbable artificial bone – a new paradigm in patient-matched scaffold-guided bone regeneration Open
Patient-matched scaffold guided bone regeneration (SGBR) has been poised to revolutionize the management of critical-sized bone defects due to trauma, tumors, infection, and congenital deformities. However, translation has been hampered by…
View article: Directing the glow: 3D feeder geometries to enhance planar bipolar electrochemiluminescence
Directing the glow: 3D feeder geometries to enhance planar bipolar electrochemiluminescence Open
Using 3D-printed pin arrays or single wires as feeders in open bipolar cells enhances luminol bipolar electrochemiluminescence (BP-ECL) and allows light to be generated in localised regions of planar stainless-steel bipolar electrodes (BPE…
View article: A comparison of the accuracy and feasibility of a low‐cost mobile application versus higher‐cost handheld <scp>3D</scp> scanner for digital ear prosthetics
A comparison of the accuracy and feasibility of a low‐cost mobile application versus higher‐cost handheld <span>3D</span> scanner for digital ear prosthetics Open
Background Facial prosthetics are an important means to rehabilitate patients with congenital or acquired facial defects. However, with a time‐consuming manual workflow and workforce shortage, access to facial prosthetics is limited in Aus…
View article: 3D‐Printed PDMS/Graphene Sensors with Tunable Sensitivity via Temperature‐Induced Crosslinking for Pressure Applications
3D‐Printed PDMS/Graphene Sensors with Tunable Sensitivity via Temperature‐Induced Crosslinking for Pressure Applications Open
The development of polydimethylsiloxane (PDMS) graphene composites with high graphene content, employed to formulate printing ink for the fabrication of tunable multilayer pressure sensors via 3D printing is presented. This study demonstra…
View article: Innervation in corneal bioengineering
Innervation in corneal bioengineering Open
Given the crucial role nerves play in maintaining corneal function and integrity, the ability of bioengineered cornea to demonstrate functional nerve regeneration directly influences their longevity and stability. Despite advances in biofa…
View article: Machine learning-generated compression modulus database for 3D printing of gelatin methacryloyl
Machine learning-generated compression modulus database for 3D printing of gelatin methacryloyl Open
3D bioprinting enables the fabrication of printable tissues, including those for neural, cartilage, and skin repair. The mechanical properties, especially stiffness, of 3D-bioprinted scaffolds are crucial for modulating cell adhesion, grow…
View article: Stem‐Cell‐Based Small‐Diameter Blood Vessels with 3D Printing
Stem‐Cell‐Based Small‐Diameter Blood Vessels with 3D Printing Open
Cardiovascular disease has emerged as the leading cause of death worldwide. Since coronary arteries, carotid arteries, and other blood vessels are prone to narrowing, small‐diameter artificial blood channels offer a crucial solution for re…
View article: Driving Deployment of Bioengineered Products—An Arduous, Sometimes Tedious, Challenging, Rewarding, Most Exciting Journey That Has to Be Made!
Driving Deployment of Bioengineered Products—An Arduous, Sometimes Tedious, Challenging, Rewarding, Most Exciting Journey That Has to Be Made! Open
More than three decades ago, we embarked on a number of bioengineering explorations using the most advanced materials and fabrication methods. In every area we ventured into, it was our intention to ensure fundamental discoveries were depl…
View article: Efficient fabrication of 3D bioprinted functional sensory neurons using an inducible Neurogenin-2 human pluripotent stem cell line
Efficient fabrication of 3D bioprinted functional sensory neurons using an inducible Neurogenin-2 human pluripotent stem cell line Open
Three-dimensional (3D) tissue models have gained recognition for their improved ability to mimic the native cell microenvironment compared to traditional two-dimensional models. This progress has been driven by advances in tissue-engineeri…
View article: Highly stretchable double‐network gel electrolytes integrated with textile electrodes for wearable thermo‐electrochemical cells
Highly stretchable double‐network gel electrolytes integrated with textile electrodes for wearable thermo‐electrochemical cells Open
Thermo‐electrochemical cells (TECs) provide a new potential for self‐powered devices by converting heat energy into electricity. However, challenges still remain in the fabrication of flexible and tough gel electrolytes and their compatibi…
View article: Design, construction, and dosimetry of 3D printed heterogeneous phantoms for synchrotron brain cancer radiation therapy quality assurance
Design, construction, and dosimetry of 3D printed heterogeneous phantoms for synchrotron brain cancer radiation therapy quality assurance Open
Objective. This study aims to design, manufacture, and test 3D printed quality assurance (QA) dosimetry phantoms for synchrotron brain cancer radiation therapy at the Australian synchrotron. Approach. Fabricated 3D printed phantoms from si…
View article: 3D printing collagen type IV for corneal endothelium transplantation
3D printing collagen type IV for corneal endothelium transplantation Open
Collagen type IV (Col-IV) is a critical matrix protein component in the basement membrane. In the cornea, it is the key contributor to the formation of Descemet’s membrane — the layer for corneal endothelial cells to reside on.…
View article: Electrofluidic control for textile‐based cell culture: Identification of appropriate conditions required to integrate cell culture with electrofluidics
Electrofluidic control for textile‐based cell culture: Identification of appropriate conditions required to integrate cell culture with electrofluidics Open
Electric field–driven microfluidics, known as electrofluidics, is a novel attractive analytical tool when it is integrated with low‐cost textile substrate. Textile‐based electrofluidics, primarily explored on yarn substrates, is in its ear…
View article: Novel 3D textile structures and geometries for electrofluidics
Novel 3D textile structures and geometries for electrofluidics Open
The integration of microfluidics with electric field control, commonly referred to as electrofluidics, has led to new opportunities for biomedical analysis. The requirement for closed microcapillary channels in microfluidics, typically for…
View article: Electrochemical CO2 reduction and mineralisation in calcium containing electrolytes
Electrochemical CO2 reduction and mineralisation in calcium containing electrolytes Open
One of the key challenges of room temperature aqueous CO2 electrolysis technology is the carbon losses because of carbonate formation. It is desirable if carbonate ions could be utilized concurrently for a useful process. Herein, we devise…
View article: Copper/Polyaniline Interfaces Confined CO<sub>2</sub> Electroreduction for Selective Hydrocarbon Production
Copper/Polyaniline Interfaces Confined CO<sub>2</sub> Electroreduction for Selective Hydrocarbon Production Open
Polyaniline (PANI) provides an attractive organic platform for CO 2 electrochemical reduction due to the ability to adsorb CO 2 molecules and in providing means to interact with metal nanostructures. In this work, a novel PANI supported co…
View article: Fabrication of Biomedical Electrodes Using Printing Approaches
Fabrication of Biomedical Electrodes Using Printing Approaches Open
In this review, we focus on the fabrication of electrodes, using printing techniques. Generally speaking, electrodes are comprised of a metal conductor with a metal lead (sometimes the same material) for the conduction of electrical curren…
View article: Chondrocyte harvest viability of auricular and nasal septal cartilage in a sheep model
Chondrocyte harvest viability of auricular and nasal septal cartilage in a sheep model Open
Introduction: Autologous techniques for reconstruction of cartilaginous structures of the head and neck are limited by donor cartilage volume, donor site morbidity and inconsistent results. Bioprinting combines “bioinks” consisting of livi…