Johnson George
YOU?
Author Swipe
View article: Identifying dementia risk profiles for targeted interventions: A latent class analysis of at‐risk middle‐aged Australians
Identifying dementia risk profiles for targeted interventions: A latent class analysis of at‐risk middle‐aged Australians Open
INTRODUCTION This study aimed to identify distinct dementia risk profiles in middle‐aged adults with two or more potential dementia risk factors, to inform targeted prevention strategies. METHODS Cross‐sectional analysis of baseline sociod…
View article: A systematic review of targeted dementia risk reduction interventions in middle-aged adults in Primary Care
A systematic review of targeted dementia risk reduction interventions in middle-aged adults in Primary Care Open
Current evidence for multidomain dementia risk-reduction interventions in mid-life is not definitive; however, given their substantive potential benefits and likely limited harms, they may be considered for implementation in clinical pract…
View article: Mitigating Antimicrobial Resistance through Strategic Design of Multimodal Antibacterial Agents Based on 1,2,3-Triazole with Click Chemistry
Mitigating Antimicrobial Resistance through Strategic Design of Multimodal Antibacterial Agents Based on 1,2,3-Triazole with Click Chemistry Open
Drug-resistant bacterial infections impose a major threat to human health, as current antibiotic treatments are becoming increasingly ineffective. Priority has been given to the development of alternative medications to curb the developmen…
View article: Impact of advice to quit smoking on rating of care and anticipation of stigma in primary care
Impact of advice to quit smoking on rating of care and anticipation of stigma in primary care Open
Aim: We assessed patient experience of care, comparing current and past smokers, and whether frequency of advice to quit smoking impacts patient rating of care. Background: Experience of care may be a concern for people who smoke and affec…
View article: Guillain Barré Syndrome Mimicking Brain Death: A Case Report
Guillain Barré Syndrome Mimicking Brain Death: A Case Report Open
Here, we present a case of Guillain-Barré syndrome (GBS) that mimicked brain death. A 66-year-old lady with a medical history of breast cancer (now receiving hormone therapy), hypertension, and hypothyroidism, presented to the emergency de…
View article: Environmental impact of inhaled medicines: A Thoracic Society of Australia and New Zealand position statement
Environmental impact of inhaled medicines: A Thoracic Society of Australia and New Zealand position statement Open
Globally, more than 1.2 billion inhalers are purchased for asthma and chronic obstructive pulmonary disease (COPD) annually. In Australia and New Zealand, pressurized metered dose inhalers (pMDIs) are the leading delivery device prescribed…
View article: Are People Living With Dementia Receiving High Intensity Statin Therapy After Stroke? A Population‐Based Cohort Study
Are People Living With Dementia Receiving High Intensity Statin Therapy After Stroke? A Population‐Based Cohort Study Open
Background and Aims This Australian population‐based study investigated statin intensity after hospitalization for ischemic stroke in a matched cohort of people living with and without dementia. Methods We identified all patients aged ≥ 30…
View article: Pharmacist E‐script transcription service initiated nicotine replacement therapy uptake in pre‐admission clinic: A pilot study
Pharmacist E‐script transcription service initiated nicotine replacement therapy uptake in pre‐admission clinic: A pilot study Open
Background Pharmacist‐led smoking cessation programs in pre‐admission clinics (PAC) have shown to increase quit attempts and achieve abstinence by the day of surgery (DOS). Aims To evaluate the feasibility of Pharmacist E‐script Transcript…
View article: Credentialed pharmacist-led home medicines reviews targeting treatable traits and their impact on health outcomes in people with COPD
Credentialed pharmacist-led home medicines reviews targeting treatable traits and their impact on health outcomes in people with COPD Open
Background Patients with COPD should engage in self-management strategies targeting behavioural traits and lifestyle risk factors for optimal outcomes. Aim To evaluate the impact of credentialed pharmacist-led home medicines review (HMR) t…
View article: Varenicline and Nicotine Replacement Therapy for Smokers Admitted to Hospitals
Varenicline and Nicotine Replacement Therapy for Smokers Admitted to Hospitals Open
Importance Varenicline is the most effective sole pharmacotherapy for smoking cessation. If used in combination with nicotine replacement therapy (NRT), cessation rates may be further improved, but the efficacy and safety of the combinatio…
View article: Case-Finding and Treatment Effects in COPD: Secondary Analysis of an Interdisciplinary Intervention Trial
Case-Finding and Treatment Effects in COPD: Secondary Analysis of an Interdisciplinary Intervention Trial Open
Despite useful insights into the impacts of case-finding and early treatments, this study, like most others, was not sufficiently powered. Further larger studies or combining sub-groups across studies are required.
View article: Fidelity of a home-based pulmonary rehabilitation program in people with COPD referred from primary care
Fidelity of a home-based pulmonary rehabilitation program in people with COPD referred from primary care Open
Purpose: Pulmonary rehabilitation (PR) is highly effective but underutilised. Pathways to home-based PR (HBPR) from general practice could improve utilisation, but program fidelity in this setting is unknown. This study aimed to explore th…
View article: A novel, multidomain, primary care nurse-led and mHealth-assisted intervention for dementia risk reduction in middle-aged adults (HAPPI MIND): study protocol for a cluster randomised controlled trial
A novel, multidomain, primary care nurse-led and mHealth-assisted intervention for dementia risk reduction in middle-aged adults (HAPPI MIND): study protocol for a cluster randomised controlled trial Open
Introduction Middle-aged multidomain risk reduction interventions targeting modifiable risk factors for dementia may delay or prevent a third of dementia cases in later life. We describe the protocol of a cluster randomised controlled tria…
View article: Cough in Children and Adults: Diagnosis, Assessment and Management (<scp>CICADA</scp>). Summary of an updated position statement on chronic cough in Australia
Cough in Children and Adults: Diagnosis, Assessment and Management (<span>CICADA</span>). Summary of an updated position statement on chronic cough in Australia Open
Introduction Cough is the most common symptom leading to medical consultation. Chronic cough results in significant health care costs, impairs quality of life, and may indicate the presence of a serious underlying condition. Here, we prese…
View article: Trend over time on knowledge of the health effects of cigarette smoking and smokeless tobacco use in Bangladesh: Findings from the International Tobacco Control Policy Evaluation Bangladesh Surveys
Trend over time on knowledge of the health effects of cigarette smoking and smokeless tobacco use in Bangladesh: Findings from the International Tobacco Control Policy Evaluation Bangladesh Surveys Open
Introduction Cigarette smoking and smokeless tobacco (ST) use are prevalent in Bangladesh. This longitudinal study examined how knowledge of the health effects of smoking and ST use in Bangladesh has changed overtime with the country's acc…
View article: Different Case Finding Approaches to Optimise COPD Diagnosis: Evidence from the RADICALS Trial
Different Case Finding Approaches to Optimise COPD Diagnosis: Evidence from the RADICALS Trial Open
Handheld micro-spirometers can facilitate case finding of COPD in smokers and ex-smokers attending general practice. The fixed ratio criterion currently recommended by COPD-X guidelines offers the simplest method for diagnosing COPD in Aus…
View article: Diabetes treatment deintensification in Australians with dementia compared to the general population: A national cohort study
Diabetes treatment deintensification in Australians with dementia compared to the general population: A national cohort study Open
Background Diagnosis of dementia may change peoples' goals of care. In people with diabetes, this may lead to relaxing treatment targets and reducing the use of diabetes medications. The aim of this study was to examine changes in diabetes…
View article: Multi-domain prognostic models used in middle-aged adults without known cognitive impairment for predicting subsequent dementia
Multi-domain prognostic models used in middle-aged adults without known cognitive impairment for predicting subsequent dementia Open
We identified 14 unique multi-domain prognostic models used in middle-aged adults for predicting subsequent dementia. Diabetes, hypertension, obesity, and smoking were the most common modifiable risk factors used as predictors in the model…
View article: Management of hypertensive disorders of pregnancy in two Australian tertiary care maternity hospitals
Management of hypertensive disorders of pregnancy in two Australian tertiary care maternity hospitals Open
Background Hypertensive disorders of pregnancy (HDP) are common obstetric medical problems. Compliance with clinical guidelines and evidence from major trials has the potential to translate to significantly improve maternal and perinatal o…
View article: Validity of three risk prediction models for dementia or cognitive impairment in Australia
Validity of three risk prediction models for dementia or cognitive impairment in Australia Open
Background no studies have compared the predictive validity of different dementia risk prediction models in Australia. Objectives (i) to investigate the predictive validity of the Australian National University-Alzheimer’s Disease Risk Ind…
View article: Evaluation of Metered Dose Inhaler Use Technique and Response to Educational Training
Evaluation of Metered Dose Inhaler Use Technique and Response to Educational Training Open
Inhalation technique of patients improves after imparting systematic educational intervention. A practical demonstration of all the steps proved more effective than simple verbal/written advice. In view of increasing errors being committed…
View article: Which smokers enroll in a hospital based smoking cessation trial? Survey of smoking related behaviors, quit attempts, and motivation to quit
Which smokers enroll in a hospital based smoking cessation trial? Survey of smoking related behaviors, quit attempts, and motivation to quit Open
Background Understanding smoking behaviors in hospital patients who smoke may improve inpatient cessation treatments. This study aimed to describe smoking‐related behaviors, past‐quit attempts, and self‐reported difficulties experienced in…
View article: Characterising the use of varenicline: an analysis of the Australian dispensing claims data
Characterising the use of varenicline: an analysis of the Australian dispensing claims data Open
Background and aims In Australia, patterns of use of smoking cessation medications and factors associated with their dispensing are currently not known. This study aimed to measure the demographic and clinical factors associated with varen…
View article: Educational interventions for health professionals managing chronic obstructive pulmonary disease in primary care
Educational interventions for health professionals managing chronic obstructive pulmonary disease in primary care Open
The evidence of efficacy was equivocal for educational interventions for health professionals in primary care on the proportion of COPD diagnoses confirmed with spirometry, the proportion of patients with COPD who participate in pulmonary …
View article: Multi-domain prognostic models used in middle aged adults without known cognitive impairment for predicting subsequent dementia
Multi-domain prognostic models used in middle aged adults without known cognitive impairment for predicting subsequent dementia Open
Objectives: This is a protocol for a Cochrane Review (prognosis). The objectives are as follows:. Primary objective Identify all available multi-domain prognostic models (that is, models involving two or more modifiable risk factors for de…