Georgios Klironomos
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View article: Pharmacological Treatment of Degenerative Cervical Myelopathy: A Critical Review of Current Evidence
Pharmacological Treatment of Degenerative Cervical Myelopathy: A Critical Review of Current Evidence Open
Degenerative cervical myelopathy (DCM) is the leading cause of spinal cord dysfunction in adults, representing substantial morbidity and significant financial and resource burdens. Typically, patients with progressive DCM will eventually r…
View article: Staged Approach for Petroclival Meningioma Resection
Staged Approach for Petroclival Meningioma Resection Open
Introduction Petroclival meningiomas represent very uncommon and challenging tumors. Surgical morbidity is high due to the difficult and complex approaches to this area. In the present video presentation, we demonstrate a staged-approach s…
View article: Surgical Strategy in Large Vestibular Schwannoma
Surgical Strategy in Large Vestibular Schwannoma Open
Particular care to facial nerve function preservation should be the ultimate goal in surgery for large vestibular schwannomas. We present a 60-year-old patient who presented with an enlarging right vestibular schwannoma and nonserviceable …
View article: Manuel Bernal-Sprekelsen, Isam Alobid (ed): Endoscopic approaches to the paranasal sinuses and skull base. A step-by-step anatomic dissection guide
Manuel Bernal-Sprekelsen, Isam Alobid (ed): Endoscopic approaches to the paranasal sinuses and skull base. A step-by-step anatomic dissection guide Open
View article: Expanded Endoscopic Transsphenoidal Resection of Tuberculum Sella Meningioma Invading the Optic Canal
Expanded Endoscopic Transsphenoidal Resection of Tuberculum Sella Meningioma Invading the Optic Canal Open
A 61-year-old male patient presented with recurrent malignant meningioma involving the left optic canal and decreased vision from the left eye. The patient had undergone orbital exenteration on the right 2 years ago. The decision to treat …
View article: Lateral Supraorbital Craniotomy for Tuberculum Sella Meningioma Resection
Lateral Supraorbital Craniotomy for Tuberculum Sella Meningioma Resection Open
Tuberculum sella meningioma can be approached by either open or endoscopic approaches. The aim of this video case presentation is to highlight the nuances of the lateral supraorbital craniotomy for tuberculum sella meningioma resection. Th…
View article: Dural Arteriovenous Fistulas of the Craniocervical Junction: Anatomical Considerations, Clinical Presentation, and Microsurgical Management
Dural Arteriovenous Fistulas of the Craniocervical Junction: Anatomical Considerations, Clinical Presentation, and Microsurgical Management Open
Background Dural arteriovenous fistulas (DAVFs) of the craniocervical junction (CCJ) represent very rare arteriovenous shunts between dural arteries and veins of this area. The classification of these fistulas is based on the draining vein…
View article: Evaluation of Outcomes after Endoscopic Endonasal Surgery for Large and Giant Pituitary Macroadenoma: A Retrospective Review of 39 Consecutive Patients
Evaluation of Outcomes after Endoscopic Endonasal Surgery for Large and Giant Pituitary Macroadenoma: A Retrospective Review of 39 Consecutive Patients Open
Background The endoscopic endonasal approach for pituitary neoplasms has shown similar efficacy compared with the microscopic approach. However, outcomes and complication rates with larger macroadenomas is not as well documented. This stud…
View article: The Supracerebellar Transtentorial Approach for Treatment of Vascular Lesions of the Medial Temporo-occipital Region
The Supracerebellar Transtentorial Approach for Treatment of Vascular Lesions of the Medial Temporo-occipital Region Open
Background The supracerebellar transtentorial approach to the inferior occipital lobe, posterior medial temporal lobe, and tentorial incisura via a suboccipital craniotomy provides an adequate surgical corridor to access lesions in these a…
View article: Orbitozygomatic craniotomy and trans-sylvian approach for resection of a tuberculum sella meningioma with extension to the posterior fossa
Orbitozygomatic craniotomy and trans-sylvian approach for resection of a tuberculum sella meningioma with extension to the posterior fossa Open
Tuberculum sella meningiomas can be approached through lateral approaches including pterional/orbitozygomatic craniotomies, frontobasal craniotomy, or through expanded endoscopic transsphenoidal approaches. The authors present the case of …
View article: A cadaveric study in endoscopic 3D visualization of posterior fossa neurovascular complexes
A cadaveric study in endoscopic 3D visualization of posterior fossa neurovascular complexes Open
Background: The use of 3D endoscopy for posterior fossa surgery gradually adopted. In this study we compare the 3D to classic 2D endoscopy in evaluating neurovascular complexes in posterior fossa. Methods: Twenty retrosigmoid craniotomies,…
View article: Recurrence pattern of surgically-resected skull base versus superficial meningiomas, signs of divergent pattern
Recurrence pattern of surgically-resected skull base versus superficial meningiomas, signs of divergent pattern Open
Background: To identify differences in the recurrence pattern of surgically-resected skull base meningiomas compared with superficial intra-cranial meningiomas Methods: A retrospective hospital-based study of all patients referred to our i…
View article: Predictors of the response of cystic brain metastases to gamma knife radiosurgery
Predictors of the response of cystic brain metastases to gamma knife radiosurgery Open
Background: Gamma knife radiosurgery (GKR) is an effective treatment modality for local control of brain metastases. The predictors of response of cystic brain metastases (CBM) to GKR is not well understood. To measure progression and dete…
View article: Disparity of volumetric and linear measurements of meningioma response to gammaknife radiosurgery
Disparity of volumetric and linear measurements of meningioma response to gammaknife radiosurgery Open
Objective: To identify clinical, radiological, and dosimetric predictors of meningioma response to stereotactic radiosurgery (SRS), and post-SRS adverse radiation events (ARE). Methodology: A retrospective review was conducted. Seventy-fiv…
View article: Latency period for radiological appearance of new intracranial metastases
Latency period for radiological appearance of new intracranial metastases Open
Introduction: This study sought to determine the overall and disease-specific latency period for radiological appearance of new intracranial metastases for patients with metastatic involvement of the brain. Methods: A retrospective chart r…
View article: Predictors of survival after second surgery for recurrent glioblastoma tumours
Predictors of survival after second surgery for recurrent glioblastoma tumours Open
Background: The impact of second surgery on recurrence remains unclear, with few definitive studies to date. This study sought to identify major predictors of survival after second surgery. Methods: A retrospective chart review was conduct…
View article: Perioperative predictive factors of intracranial meningioma recurrence following surgical resection
Perioperative predictive factors of intracranial meningioma recurrence following surgical resection Open
Background: Meningiomas represent the commonest benign intracranial tumor and surgical resection is the first line treatment. Tumor recurrence after surgical resection is common. The aim of this study is to identify peri-operative predicto…
View article: Factors associated with recurrence after endoscopic transphenoidal surgery for Cushing’s disease
Factors associated with recurrence after endoscopic transphenoidal surgery for Cushing’s disease Open
Introduction: Surgical removal is the standard treatment for Cushing’s disease. Although endoscopic transsphenoidal surgical (ETS) approach has grown in popularity, its efficacy has not yet been established. Furthermore, achieving long-ter…