George Laking
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View article: ‘It affected everybody, but affected people differently’: the health and wellbeing impacts of Cyclone Gabrielle on East Coast communities of Aotearoa New Zealand
‘It affected everybody, but affected people differently’: the health and wellbeing impacts of Cyclone Gabrielle on East Coast communities of Aotearoa New Zealand Open
In February 2023, Severe Tropical Cyclone Gabrielle devastated the North Island of Aotearoa New Zealand with loss of life, extreme flooding, damage to homes, roads and infrastructure particularly in the regions of Te Tairāwhiti (Gisborne) …
View article: Vaping cessation strategies and triggers for relapse amongst people from New Zealand who have vaped
Vaping cessation strategies and triggers for relapse amongst people from New Zealand who have vaped Open
Introduction In New Zealand (NZ) vapes (e‐cigarettes) are a government‐endorsed strategy to help people stop smoking, as well as being used recreationally by people who have never smoked. Nicotine vapes are addictive and many users want to…
View article: Treatment Outcomes From Erlotinib and Gefitinib in Advanced Epidermal Growth Factor Receptor–Mutated Nonsquamous Non–Small Cell Lung Cancer in Aotearoa New Zealand From 2010 to 2020: Nationwide Whole-of-Patient-Population Retrospective Cohort Study
Treatment Outcomes From Erlotinib and Gefitinib in Advanced Epidermal Growth Factor Receptor–Mutated Nonsquamous Non–Small Cell Lung Cancer in Aotearoa New Zealand From 2010 to 2020: Nationwide Whole-of-Patient-Population Retrospective Cohort Study Open
Background Health care system–wide outcomes from routine treatment with erlotinib and gefitinib are incompletely understood. Objective The aim of the study is to describe the effectiveness of erlotinib and gefitinib during the first decade…
View article: Establishing a New Zealand brain tumour registry: understanding clinical registry formation in New Zealand
Establishing a New Zealand brain tumour registry: understanding clinical registry formation in New Zealand Open
aims: To explore the development of clinical registries in New Zealand, examine the New Zealand neuro-oncology system and assess factors relevant to establishing a national brain tumour registry in New Zealand. methods: A literature review…
View article: Tū Kaha: He mōhio ki ngā Māori o te kōmaoa waewae (Stand Strong: A qualitative study of Māori with venous leg ulcers in Aotearoa New Zealand)
Tū Kaha: He mōhio ki ngā Māori o te kōmaoa waewae (Stand Strong: A qualitative study of Māori with venous leg ulcers in Aotearoa New Zealand) Open
Venous leg ulcers have impact on people’s lives far beyond that of a skin lesion but these impacts have not been explored from an Indigenous perspective. We used a Māori-centered narrative approach to interview 13 Māori in Aotearoa New Zea…
View article: Characteristics and outcomes of lung cancer patients presenting through the emergency department: a Waikato District Health Board study
Characteristics and outcomes of lung cancer patients presenting through the emergency department: a Waikato District Health Board study Open
aim: This research examines the characteristics and survival outcomes of patients receiving a lung cancer diagnosis after attending the emergency department (ED) of Waikato hospitals in New Zealand. methods: This retrospective study was ba…
View article: Erlotinib or Gefitinib for Treating Advanced Epidermal Growth Factor Receptor Mutation–Positive Lung Cancer in Aotearoa New Zealand: Protocol for a National Whole-of-Patient-Population Retrospective Cohort Study and Results of a Validation Substudy
Erlotinib or Gefitinib for Treating Advanced Epidermal Growth Factor Receptor Mutation–Positive Lung Cancer in Aotearoa New Zealand: Protocol for a National Whole-of-Patient-Population Retrospective Cohort Study and Results of a Validation Substudy Open
Background Starting in 2010, the epidermal growth factor receptor (EGFR) kinase inhibitors erlotinib and gefitinib were introduced into routine use in Aotearoa New Zealand (NZ) for treating advanced lung cancer, but their impact in this se…
View article: Sporadic Metastatic Malignant Peripheral Nerve Sheath Tumour with an NF1 Mutation Responding to Trametinib: A Case Report
Sporadic Metastatic Malignant Peripheral Nerve Sheath Tumour with an NF1 Mutation Responding to Trametinib: A Case Report Open
Sporadically occurring malignant peripheral nerve sheath tumours (MPNSTs) can have a variety of genomic alterations including altered NF1, leading to activation of the RAS-RAF-MEK-ERK signalling pathway. Trametinib is an inhibitor of MEK1 …
View article: Review of: "Tobacco endgame intervention impacts on health gains and Māori:non-Māori health inequity: a simulation study of the Aotearoa-New Zealand Tobacco Action Plan"
Review of: "Tobacco endgame intervention impacts on health gains and Māori:non-Māori health inequity: a simulation study of the Aotearoa-New Zealand Tobacco Action Plan" Open
Building on recent progress towards the New Zealand Smokefree 2025 goal, the Government plans to introduce tobacco control legislation giving ministers powers to implement three significant new policies: a steep reduction in the number of …
View article: The impact of COVID-19 on lung cancer detection, diagnosis and treatment for Māori in Aotearoa New Zealand.
The impact of COVID-19 on lung cancer detection, diagnosis and treatment for Māori in Aotearoa New Zealand. Open
AIM: The purpose of this article is to examine disparities in the impact of the COVID-19 pandemic on access to lung cancer diagnosis and access to clinical services between Māori and non-Māori. METHODS: Using national-level data, we examin…
View article: Prescribed exercise regimen versus usual care and hypochlorous acid wound solution versus placebo for treating venous leg ulcers: study protocol for a randomised controlled trial (Factorial4VLU)
Prescribed exercise regimen versus usual care and hypochlorous acid wound solution versus placebo for treating venous leg ulcers: study protocol for a randomised controlled trial (Factorial4VLU) Open
Introduction Compression is the mainstay of treatment for venous leg ulcers (VLUs) and there are few effective adjuvant treatments. There is only observational evidence supporting the use of hypochlorous acid (HOCl) as a topical wound solu…
View article: Issue Information
Issue Information Open
Evaluation of screening practices for low bone mass and prevalence of osteoporosis and fractures
View article: Effectiveness and safety of nicotine patches combined with e-cigarettes (with and without nicotine) for smoking cessation: study protocol for a randomised controlled trial
Effectiveness and safety of nicotine patches combined with e-cigarettes (with and without nicotine) for smoking cessation: study protocol for a randomised controlled trial Open
Introduction Evidence indicates e-cigarettes can help people quit smoking; however, more confirmatory trials are needed. To date, no trials have evaluated the effectiveness and safety of combining nicotine patches with e-cigarettes (with a…
View article: The effectiveness and safety of combining varenicline with nicotine e-cigarettes for smoking cessation in people with mental illnesses and addictions: study protocol for a randomised-controlled trial
The effectiveness and safety of combining varenicline with nicotine e-cigarettes for smoking cessation in people with mental illnesses and addictions: study protocol for a randomised-controlled trial Open
Australian NZ Clinical Trial Registry: ACTRN12616001355460 (29 September 2016).
View article: Lung cancer mutation testing: a clinical retesting study of agreement between a real-time PCR and a mass spectrometry test
Lung cancer mutation testing: a clinical retesting study of agreement between a real-time PCR and a mass spectrometry test Open
To investigate the clinical validity and utility of tests for detecting Epidermal Growth Factor Receptor (EGFR) gene mutations in non-squamous non-small cell lung cancer patients, tumour DNA extracts from 532 patients previously tested by …
View article: Mind the gap: An analysis of foregone health gains from unfunded cancer medicines in New Zealand
Mind the gap: An analysis of foregone health gains from unfunded cancer medicines in New Zealand Open
Publicly funded cancer medicines listed on the New Zealand Pharmaceutical Schedule were compared with those listed on the Australian Pharmaceutical Benefits Scheme. To quantify the health gains offered by the cancer medicines funded in Aus…