George Yanni
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View article: Gastric antral vascular ectasia: A rare etiology of gastrointestinal bleeding in children
Gastric antral vascular ectasia: A rare etiology of gastrointestinal bleeding in children Open
Gastrointestinal bleeding is relatively common in children. While most patients present with mild bleeding, gastric antral vascular ectasia (GAVE) is a rare but potentially life‐threatening cause. GAVE is typically associated with chronic …
View article: Letter to the editor: A response to Hildreth and Schwimmer
Letter to the editor: A response to Hildreth and Schwimmer Open
We are responding to Hildreth and Schwimmer's letter regarding our case report, "A Case of Pediatric Alcohol-Associated Hepatitis Evaluated for Liver Transplant Listing."1, 2 The letter makes the excellent point that, based on our patient'…
View article: Safety and Immunogenicity of Live Viral Vaccines in a Multicenter Cohort of Pediatric Transplant Recipients
Safety and Immunogenicity of Live Viral Vaccines in a Multicenter Cohort of Pediatric Transplant Recipients Open
Importance Live vaccines (measles-mumps-rubella [MMR] and varicella-zoster virus [VZV]) have not been recommended after solid organ transplant due to concern for inciting vaccine strain infection in an immunocompromised host. However, the …
View article: A Case of Pediatric Alcohol‐Associated Hepatitis Evaluated for Liver Transplant Listing
A Case of Pediatric Alcohol‐Associated Hepatitis Evaluated for Liver Transplant Listing Open
Alcohol‐associated hepatitis (AH) refers to liver injury from alcoholic intake that usually occurs after years of heavy alcohol abuse. Frequent, heavy alcohol consumption causes hepatic inflammation, fibrosis, and cirrhosis. Some patients …
View article: Living donor liver paired exchange between pediatric and adult recipients due to donor graft size mismatch
Living donor liver paired exchange between pediatric and adult recipients due to donor graft size mismatch Open
Living donor liver transplantation is an effective means to decrease organ shortage. However, many potential living donors are currently being denied due to ABO incompatibility or inadequate donor liver volume. Liver paired exchange (LPE) …
View article: Pediatric acute liver failure: Reexamining key clinical features, current management, and research prospects
Pediatric acute liver failure: Reexamining key clinical features, current management, and research prospects Open
This review aims to synthesize the most updated research, outcomes, and trends in the field of pediatric liver transplantation (LT), specifically focusing on children who have suffered from acute liver failure. Pediatric acute liver failur…
View article: Clinical Value of Surveillance Biopsies in Pediatric Liver Transplantation
Clinical Value of Surveillance Biopsies in Pediatric Liver Transplantation Open
Although pediatric liver transplantation (LT) results in excellent long‐term outcomes, a high incidence of early acute cellular rejection and late graft fibrosis persists. Routine measurement of allograft enzymes may not reliably detect re…
View article: Immunologic benefits of maternal living donor allografts in pediatric liver transplantation: fewer rejection episodes and no evidence of de novo allosensitization
Immunologic benefits of maternal living donor allografts in pediatric liver transplantation: fewer rejection episodes and no evidence of de novo allosensitization Open
Background Pediatric liver transplant (LT) recipients of maternal living liver donor (LLD) grafts have been reported to experience fewer rejection episodes. However, it is unclear whether this benefit translates to reduction in developing …
View article: Immunologic and Survival Benefits of Combined Heart-liver Transplantation in Children
Immunologic and Survival Benefits of Combined Heart-liver Transplantation in Children Open
Combined heart-liver transplant (CHLT) in adults has been increasingly reported in the United States, with long-term outcomes that match liver or heart transplant alone (HTA).1 In pediatrics, a tiny experience has proven feasibility, with …
View article: COLORECTAL ADENOCARCINOMA DEVELOPING IN A YOUNG FEMALE WITH OVERLAP SYNDROME AND VERY EARLY ONSET-INFLAMMATORY BOWEL DISEASE: A CASE REPORT
COLORECTAL ADENOCARCINOMA DEVELOPING IN A YOUNG FEMALE WITH OVERLAP SYNDROME AND VERY EARLY ONSET-INFLAMMATORY BOWEL DISEASE: A CASE REPORT Open
We present a 4-year-old female diagnosed with very-early onset inflammatory bowel disease (VEO-IBD), ulcerative colitis type, and overlap syndrome based on clinical presentation, blood and stool studies, diagnostic endoscopies and liver bi…