Georgia A. Pilkington
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View article: Bioinspired lipid coated porous particle as inhalable carrier with pulmonary surfactant adhesion and mucus penetration
Bioinspired lipid coated porous particle as inhalable carrier with pulmonary surfactant adhesion and mucus penetration Open
There is an urgent need for novel inhalable drug carriers to fight respiratory infections. Lipid-coated mesoporous silica particles (LC-MSPs) combine the biocompatibility of lipids with the aerosolization properties of micronized low-densi…
View article: Disordered mesoporous silica particles: an emerging platform to deliver proteins to the lungs
Disordered mesoporous silica particles: an emerging platform to deliver proteins to the lungs Open
Pulmonary delivery and formulation of biologics are among the more complex and growing scientific topics in drug delivery. We herein developed a dry powder formulation using disordered mesoporous silica particles (MSP) as the sole excipien…
View article: Anion Architecture Controls Structure and Electroresponsivity of Anhalogenous Ionic Liquids in a Sustainable Fluid
Anion Architecture Controls Structure and Electroresponsivity of Anhalogenous Ionic Liquids in a Sustainable Fluid Open
Three nonhalogenated ionic liquids (ILs) dissolved in 2-ethylhexyl laurate (2-EHL), a biodegradable oil, are investigated in terms of their bulk and electro-interfacial nanoscale structures using small-angle neutron scattering (SANS) and n…
View article: Inhalable porous particles as dual micro-nano carriers demonstrating efficient lung drug delivery for treatment of tuberculosis
Inhalable porous particles as dual micro-nano carriers demonstrating efficient lung drug delivery for treatment of tuberculosis Open
Inhalation therapy treating severe infectious disease is among the more complex and emerging topics in controlled drug release. Micron-sized carriers are needed to deposit drugs into the lower airways, while nano-sized carriers are of pref…
View article: Tribotronic Control of Ionic Boundary Films
Tribotronic Control of Ionic Boundary Films Open
The effect of electric potential on the lubricating adsorbed ionic films has been studied for a non-halogenated phosphonium orthoborate ionic liquid used as an additive in a biodegradable oil. A tribotronic system, designed around a ball-o…
View article: Micro- to Nano- and from Surface to Bulk: Influence of Halogen-Free Ionic Liquid Architecture and Dissociation on Green Oil Lubricity
Micro- to Nano- and from Surface to Bulk: Influence of Halogen-Free Ionic Liquid Architecture and Dissociation on Green Oil Lubricity Open
Four nonhalogenated ionic liquids (ILs) based on the same phosphonium cation are investigated in terms of the anion suitability for enhancing the lubricity of a biodegradable oil. For all test conditions, typical for industrial machine com…
View article: Tuneable interfacial surfactant aggregates mimic lyotropic phases and facilitate large scale nanopatterning
Tuneable interfacial surfactant aggregates mimic lyotropic phases and facilitate large scale nanopatterning Open
Self-assembly of insoluble surfactants imposes curvature restrictions on the air–water interface which leads to 3D nanopatterns that can be deposited onto solid surfaces.
View article: Electroresponsive structuring and friction of a non-halogenated ionic liquid in a polar solvent: effect of concentration
Electroresponsive structuring and friction of a non-halogenated ionic liquid in a polar solvent: effect of concentration Open
Neutron reflectivity and atomic force microscopy results reveal the electroresponsive interfacial structuring and nano-frictional properties of ionic liquid (IL) lubricant mixtures with a polar solvent are strongly dependent on bulk IL con…
View article: Interfacial structuring of non-halogenated imidazolium ionic liquids at charged surfaces: effect of alkyl chain length
Interfacial structuring of non-halogenated imidazolium ionic liquids at charged surfaces: effect of alkyl chain length Open
Control of the interfacial structures of ionic liquids (ILs) at charged interfaces is important to many of their applications, including in energy storage solutions, sensors and advanced lubrication technologies utilising electric fields.
View article: Effect of water on the electroresponsive structuring and friction in dilute and concentrated ionic liquid lubricant mixtures
Effect of water on the electroresponsive structuring and friction in dilute and concentrated ionic liquid lubricant mixtures Open
The influence of ambient levels of water on the electroresponsive interfacial structuring and nanofriction of ionic liquid lubricant mixtures has been investigated by neutron reflectivity and atomic force microscopy.
View article: 3D texturing of the air–water interface by biomimetic self-assembly
3D texturing of the air–water interface by biomimetic self-assembly Open
The air–water interface can be textured according to the same self-assembly packing criteria that determine the wealth of 3D structures found in micellar and other amphiphilic meso-phases.
View article: 3D Texturing of the Water–Air Interface by Biomimetic Self-Assembly
3D Texturing of the Water–Air Interface by Biomimetic Self-Assembly Open
A simple, insoluble monolayer of fatty acid is shown to induce 3D nanotexturing of the water–air interface. This advance has been achieved through the study of monolayers of a methyl-branched long chain fatty acid, analogous to those found…
View article: 3D Texturing of the Water–Air Interface by Biomimetic Self-Assembly
3D Texturing of the Water–Air Interface by Biomimetic Self-Assembly Open
A simple, insoluble monolayer of fatty acid is shown to induce 3D nanotexturing of the water–air interface. This advance has been achieved through the study of monolayers of a methyl-branched long chain fatty acid, analogous to those found…
View article: Anomalous Interfacial Structuring of a Non-Halogenated Ionic Liquid: Effect of Substrate and Temperature
Anomalous Interfacial Structuring of a Non-Halogenated Ionic Liquid: Effect of Substrate and Temperature Open
We investigate the interfacial properties of the non-halogenated ionic liquid (IL), trihexyl(tetradecyl)phosphonium bis(mandelato)borate, [P6,6,6,14][BMB], in proximity to solid surfaces, by means of surface force measurement. The system c…