Georgiana Bianca Constantin
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View article: Assessment of physical activity levels and sedentary behavior in students using the Global Physical Activity Questionnaire
Assessment of physical activity levels and sedentary behavior in students using the Global Physical Activity Questionnaire Open
Physical activity plays a crucial role in maintaining both physical and mental health, being especially important among university students who are often exposed to a sedentary lifestyle. Lack of physical activity can lead to various healt…
View article: Unexpected Long-Term Survival and Downstaging in Oligometastatic Non-Small Cell Lung Cancer Treated with Multimodal Therapy
Unexpected Long-Term Survival and Downstaging in Oligometastatic Non-Small Cell Lung Cancer Treated with Multimodal Therapy Open
Background: Advances in the treatment of non-small cell lung cancer in the last 5 years (new techniques in radiotherapy, including stereotactic ablative radiotherapy, new targeted therapies and advances in immunotherapy) have increased the…
View article: Prognostic Factors of Postoperative Mortality in Patients with Complicated Right Colon Cancer
Prognostic Factors of Postoperative Mortality in Patients with Complicated Right Colon Cancer Open
The incidence of right colon cancer presenting in a stage with complications is significant. There are major differences in therapeutic approach between elective colon cancer surgery and emergency surgery. Complications such as hemorrhage,…
View article: Particular Aspects of Cardiac Rhythm Disorders in Pediatric Patients
Particular Aspects of Cardiac Rhythm Disorders in Pediatric Patients Open
Background: Cardiac rhythm disorders in children and adolescents have a high incidence. In certain conditions, sudden death may occur. Materials and Methods: We conducted a prospective study including 199 patients divided into two subgroup…
View article: Prognostic Factors of Postoperative Mortality in Patients with Complicated Right Colon Cancer
Prognostic Factors of Postoperative Mortality in Patients with Complicated Right Colon Cancer Open
The incidence of right colon cancer presented in the stage of complications is significant. There are major differences in therapeutic approach between elective colon cancer surgery and emergency surgery. Complications such as hemorrhage, …
View article: THE INTESTINAL INSUFFICIENCY SYNDROME AND THE SYSTEMIC INFLAMMATORY RESPONSE SYNDROME IN ACUTE PERITONITIS IN CHILDREN
THE INTESTINAL INSUFFICIENCY SYNDROME AND THE SYSTEMIC INFLAMMATORY RESPONSE SYNDROME IN ACUTE PERITONITIS IN CHILDREN Open
Background:According to many published research in the literature, acute peritonitis in children is a topic of interest, first due to the disorders produced by the growing organism and, on the other hand, due to the problems that may appea…
View article: Assessment of psycho-emotional symptoms in cancer patients in an Oncology-Palliative Care Department from Romania
Assessment of psycho-emotional symptoms in cancer patients in an Oncology-Palliative Care Department from Romania Open
Introduction. Anxiety and depression have an increased prevalence in cancer patients, especially in those in an advanced stage of the disease. These disorders have a major impact on the social life, existential concerns and quality of life…
View article: Hydatid Cysts of the Psoas Muscle: Insights from the Past Five Years
Hydatid Cysts of the Psoas Muscle: Insights from the Past Five Years Open
Echinococcosis represents a major public health issue and continues to be endemic in various regions around the world. Hydatid cysts are commonly located in the liver (primary site), followed by the lungs (secondary site). However, they ar…
View article: Anxiety and Depression in Advanced and Metastatic Lung Cancer Patients—Correlations with Performance Status and Type of Treatment
Anxiety and Depression in Advanced and Metastatic Lung Cancer Patients—Correlations with Performance Status and Type of Treatment Open
Background and Objectives: The treatment of advanced and metastatic lung cancer is multimodal, and it is coordinated by a multidisciplinary team. Anxiety and depression occur frequently in patients with lung cancer, creating considerable d…
View article: Complete Favorable Response after Second-Line Immunotherapy in Stage IV Non-Small Lung Cancer with Visceral Metastases and Operated Brain Metastasis
Complete Favorable Response after Second-Line Immunotherapy in Stage IV Non-Small Lung Cancer with Visceral Metastases and Operated Brain Metastasis Open
Introduction: Patients with non-small cell lung cancer (NSCLC) and brain metastatic disease have an unfavorable prognosis. The goal of the treatment in stage IV NSCLC is to increase the survival rate and to improve the quality of life. Cas…
View article: The pathological and immunohistochemical profile of tumor angiogenesis in perforated sigmoid carcinoma–Case report and short literature review
The pathological and immunohistochemical profile of tumor angiogenesis in perforated sigmoid carcinoma–Case report and short literature review Open
Background: Little is known about the physiopathological factors or mechanisms that underlie tumor invasion of the serosa and lead to perforation in the peritoneal cavity. The aim of the work was to analyze the pathological and immunohisto…
View article: Fetal acrania diagnosed at 17 weeks of gestation by 2D/3D ultrasound: a case report and literature review
Fetal acrania diagnosed at 17 weeks of gestation by 2D/3D ultrasound: a case report and literature review Open
Acrania is a fetal malformation characterized by complete or partial absence of the calvaria above the orbits and supraciliary ridge. No exact mechanism is demonstrated for this anomaly but disturbances in mesenchymal migration during the …
View article: The Integration of Psychological Intervention in the Multimodal Treatment of Patients with Prostate Cancer and Erectile Dysfunction
The Integration of Psychological Intervention in the Multimodal Treatment of Patients with Prostate Cancer and Erectile Dysfunction Open
Male sexual dysfunction refers to a lack of attraction and a lack of normal sexual performance. The most common sexual dysfunction in men is erectile dysfunction. Erectile dysfunction is the inability to achieve an erection or to sustain s…
View article: Unraveling the Mechanisms of Intestinal Insufficiency in Acute Peritonitis: A Comprehensive Overview
Unraveling the Mechanisms of Intestinal Insufficiency in Acute Peritonitis: A Comprehensive Overview Open
Acute peritonitis is a severe complication of abdominal surgery with a high mortality rate. Intes-tinal insufficiency syndrome (IIS) is a key factor in the progression of peritonitis, contributing significantly to morbidity and mortality. …
View article: Immunotherapy Combined with Radiation in Malignant Melanoma without BRAF Mutations Brain Metastases—Favorable Response after Immunotherapy Continued beyond Progression
Immunotherapy Combined with Radiation in Malignant Melanoma without BRAF Mutations Brain Metastases—Favorable Response after Immunotherapy Continued beyond Progression Open
We present the case of a patient who was diagnosed in 2018 with nodular Malignant Melanoma (MM) without BRAF V 600 mutations stage 3 C (pT4b pN1a M0), and who underwent adjuvant citokines treatment with Interferon alpha 2b-48 weeks. Immuno…
View article: The Complexity of Treatments and the Multidisciplinary Team—A Rare Case of Long-Term Progression—Free Survival in Prostate Cancer until Development of Liver and Brain Metastases
The Complexity of Treatments and the Multidisciplinary Team—A Rare Case of Long-Term Progression—Free Survival in Prostate Cancer until Development of Liver and Brain Metastases Open
Introduction: Prostate cancer has no initial clinical manifestation in the case of brain metastases since they are asymptomatic at first. This is why there is a high risk for clinicians to overlook these lesions, and they are often confuse…
View article: Considerations Regarding Online Group Psychotherapy Sessions for Breast Cancer Patients in Active Phase of Oncological Treatment
Considerations Regarding Online Group Psychotherapy Sessions for Breast Cancer Patients in Active Phase of Oncological Treatment Open
Introduction: The aim of this study is to evaluate the results of online group meetings for breast cancer patients in the active phase of treatment. The group therapy sessions took place weekly, synchronously, online, on Zoom, with a total…
View article: Epidermolysis Bullosa—A Kindler Syndrome Case Report and Short Literature Review
Epidermolysis Bullosa—A Kindler Syndrome Case Report and Short Literature Review Open
Introduction: Epidermolysis bullosa (EB) represents a group of rare disorders, genetically determined, characterized by skin fragility, blister formation and erosions due to minimal trauma. Depending on the ultrastructural level of skin cl…
View article: The Efficacy of Immunotherapy in Long-Term Survival in Non-Small Cell Lung Cancer (NSCLC) Associated with the Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)
The Efficacy of Immunotherapy in Long-Term Survival in Non-Small Cell Lung Cancer (NSCLC) Associated with the Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) Open
Introduction: The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most common cause of hyponatremia in cancer patients, occurring most frequently in patients with small cell lung cancer. However, this syndrome occur…
View article: A Novel Clinical Nomogram for Predicting Overall Survival in Patients with Emergency Surgery for Colorectal Cancer
A Novel Clinical Nomogram for Predicting Overall Survival in Patients with Emergency Surgery for Colorectal Cancer Open
Background: Long-term survival after emergency colorectal cancer surgery is low, and its estimation is most frequently neglected, with priority given to the immediate prognosis. This study aimed to propose an effective nomogram to predict …
View article: Mortality Risk Stratification in Emergency Surgery for Obstructive Colon Cancer—External Validation of International Scores, American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator (SRC), and the Dedicated Score of French Surgical Association (AFC/OCC Score)
Mortality Risk Stratification in Emergency Surgery for Obstructive Colon Cancer—External Validation of International Scores, American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator (SRC), and the Dedicated Score of French Surgical Association (AFC/OCC Score) Open
Background: The increased rates of postoperative mortality after emergency surgery for obstructive colon cancer (OCC) require the use of risk-stratification scores. The study purpose is to external validate the surgical risk calculator (SR…
View article: "A Case Report Involving Surgical Acute Abdomen Caused by a Perforated Jejunal Diverticulum"
"A Case Report Involving Surgical Acute Abdomen Caused by a Perforated Jejunal Diverticulum" Open
Jejunal diverticulum represents an extremely rare gastrointestinal pathology.The clinical diagnosis is very challenging because the usual presentation of the patient is non-specific.We report a case of acute abdomen generated by the perfor…
View article: Nomogram for Prediction of Postoperative Morbidity in Patients with Colon Cancer Requiring Emergency Therapy
Nomogram for Prediction of Postoperative Morbidity in Patients with Colon Cancer Requiring Emergency Therapy Open
BACKGROUND Postoperative complications are the major cause of mortality and prolonged hospitalization after emergency surgery for colon cancer. This study aimed to propose an effective nomogram to predict postoperative complications in ord…
View article: Diagnostic and Management of Undescended Ovary – A Preoperative Dilemma: A Case-Based Systematic Review
Diagnostic and Management of Undescended Ovary – A Preoperative Dilemma: A Case-Based Systematic Review Open
Ioana Anca Stefanopol,1,2,* Liliana Baroiu,3,4 Georgiana Bianca Constantin,1,5 Dumitru Marius Danila,2,6,* Lucreţia Anghel,3,7,* Alexandru Nechifor,3,8,* Alin Laurenţiu Tatu3,8â 10 1D…
View article: Age-Related, Sport-Specific Dysfunctions of the Shoulder and Pelvic Girdle in Athletes Table Tennis Players. Observational Study
Age-Related, Sport-Specific Dysfunctions of the Shoulder and Pelvic Girdle in Athletes Table Tennis Players. Observational Study Open
Background: Postural skills are fundamental in motor activities, so far no evidence of a direct relationship has been found, it is therefore recommended to consider the following directions, the higher the level of sports competition, the …
View article: A Short History of the BCG Vaccine
A Short History of the BCG Vaccine Open
BCG vaccine continues to be controversial, live attenuated BCG is still the only vaccine in use which is able to prevent TB in humans. It is still difficult to determine which strain should be used and further detailed analysis of the geno…
View article: Giant paraovarian cyst in an adolescent: a challenge of accurate diagnostic
Giant paraovarian cyst in an adolescent: a challenge of accurate diagnostic Open
BackgroundParaovarian cysts (POCs) are rarely seen among pediatric female patients. The diagnosis still represents a challenge. Giant POCs are exceedingly rare and only few cases have been reported in the literature.Case presentationA 17-y…
View article: The Urosepsis—A Literature Review
The Urosepsis—A Literature Review Open
Urosepsis is a very serious condition with a high mortality rate. The immune response is in the center of pathophysiology. The therapeutic management of these patients includes surgical treatment of the source of infection, antibiotic ther…
View article: INVESTIGATING LYMPH – A NEW CHALLENGE AND PERSPECTIVE IN BREAST CANCER
INVESTIGATING LYMPH – A NEW CHALLENGE AND PERSPECTIVE IN BREAST CANCER Open
Worldwide breast cancer (BC) represents one of the most common type of cancer. Mortality from this disease is declining due to new therapies, but many patients face the side effects of cancer and treatment. The most common side effect is t…