Georgios Kourounis
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View article: Donor factors influencing pancreas transplant utilization decisions; using US registry data to model evolution in decision-making over time
Donor factors influencing pancreas transplant utilization decisions; using US registry data to model evolution in decision-making over time Open
Background Pancreas transplantation remains the only definitive treatment for diabetes mellitus. However, the global number of pancreas transplants and utilisation of pancreas grafts is declining. We aimed to identify significant donor fac…
View article: Non-linear regression modelling for medical professionals; making curved paths straightforward
Non-linear regression modelling for medical professionals; making curved paths straightforward Open
Regression models provide information on complex relationships between patient factors, investigations, diagnoses, treatments, and outcomes. These inferences underpin evidence-based medicine. However, by default regression models assume st…
View article: Simultaneous Pancreas and Kidney Transplantation in Patients With Type 2 Diabetes Mellitus
Simultaneous Pancreas and Kidney Transplantation in Patients With Type 2 Diabetes Mellitus Open
The prevalence of diabetes is increasing exponentially, accompanied by an increase in chronic complications, including nephropathy. Kidney transplantation may offer freedom from dialysis but adding a pancreas addresses the underlying disea…
View article: Response to ‘Performance of large language models at the MRCS Part A: a tool for medical education?’
Response to ‘Performance of large language models at the MRCS Part A: a tool for medical education?’ Open
View article: Pre‐Donation Cardiac Arrest and Liver Transplantation Outcomes: Implications for Ischemic Preconditioning
Pre‐Donation Cardiac Arrest and Liver Transplantation Outcomes: Implications for Ischemic Preconditioning Open
Background Liver transplantation is the definitive treatment for end‐stage liver disease and some cancers. The use of livers from donors following pre‐donation cardiac arrest (PDCA), especially with prolonged downtime duration, has been li…
View article: One-Year HbA1c Predicts Long-Term Pancreas Graft Survival Following SPK Transplantation: A US Population Cohort Study
One-Year HbA1c Predicts Long-Term Pancreas Graft Survival Following SPK Transplantation: A US Population Cohort Study Open
Understanding which factors shape long-term pancreas graft outcomes after the critical first year post-transplantation is an ongoing challenge. This study assesses one-year HbA1c as a predictor of subsequent pancreas graft survival. A retr…
View article: HDM-FH treatment during static cold storage protects against ischaemic injury in a simulated kidney transplant model
HDM-FH treatment during static cold storage protects against ischaemic injury in a simulated kidney transplant model Open
View article: 349 Impact of Pre-Donation Cardiac Arrest on Liver Transplantation
349 Impact of Pre-Donation Cardiac Arrest on Liver Transplantation Open
Aim Liver transplantation is the definitive treatment for end-stage liver disease and some cancers, but organ shortages necessitate maximising donor use. Concerns about utilising livers from pre-donation cardiac arrest (PDCA) donors persis…
View article: Contrast-Enhanced Ultrasound to Assess Kidney Quality During Ex Situ Normothermic Machine Perfusion
Contrast-Enhanced Ultrasound to Assess Kidney Quality During Ex Situ Normothermic Machine Perfusion Open
Normothermic machine perfusion (NMP) provides opportunity for viability assessment of donated kidneys. Diminished microvascular perfusion, despite adequate total blood flow, is a key pathophysiology in ischaemia-mediated acute kidney injur…
View article: rmsMD: Output Results from 'rms' Models for Medical Journals
rmsMD: Output Results from 'rms' Models for Medical Journals Open
View article: 57 Agreement in visual quality assessment of donated livers and kidneys among consultant surgeons
57 Agreement in visual quality assessment of donated livers and kidneys among consultant surgeons Open
Introduction Surgeons' visual assessments represent the most common reason for non-utilisation of kidneys and livers retrieved for transplantation. While variability in organ acceptance between transplant centres is recognised, the influen…
View article: 80 Selective internal radiotherapy (SIRT) versus Hepatic artery embolization (HAE) for the treatment of neuroendocrine liver metastases
80 Selective internal radiotherapy (SIRT) versus Hepatic artery embolization (HAE) for the treatment of neuroendocrine liver metastases Open
Introduction Liver-directed therapies are an important component of palliative control of disease burden and carcinoid syndrome for unresectable liver metastases of neuroendocrine tumours. Hepatic artery embolization (HAE) and selective in…
View article: 54 Contrast-enhanced ultrasound to assess kidney quality during ex situ normothermic machine perfusion
54 Contrast-enhanced ultrasound to assess kidney quality during ex situ normothermic machine perfusion Open
Background Normothermic machine perfusion (NMP) provides opportunity for viability assessment of donated kidneys. Diminished microvascular perfusion, despite adequate total blood flow, is a key pathophysiology in ischaemia reperfusion inju…
View article: 58 Agreement in visual organ quality assessment: A comparative study between trainees and consultants
58 Agreement in visual organ quality assessment: A comparative study between trainees and consultants Open
Introduction Optimising organ utilisation relies on accurate organ quality assessments. Though multiple factors influence decisions, subjective visual assessments of hepatic steatosis and renal perfusion remain the most reported reasons of…
View article: 27 Deep learning for automated image segmentation of in situ livers from organ retrieval photographs
27 Deep learning for automated image segmentation of in situ livers from organ retrieval photographs Open
Introduction Assessing hepatic steatosis during liver donation is crucial but challenging due to reliance on subjective visual assessments. Artificial intelligence (AI) models can offer an objective alternative, if computers can accurately…
View article: 157 Automating detection and delineation of pancreas from surrounding tissue in pancreas retrieval photographs
157 Automating detection and delineation of pancreas from surrounding tissue in pancreas retrieval photographs Open
Introduction Successful pancreas transplantation requires accurate assessment of donor pancreatic steatosis. Unlike other organs, the pancreas cannot be biopsied if intended for transplantation. Subjective visual assessment of steatosis is…
View article: Donor Time to Death and Kidney Transplant Outcomes in the Setting of a 3-Hour Minimum Wait Policy
Donor Time to Death and Kidney Transplant Outcomes in the Setting of a 3-Hour Minimum Wait Policy Open
Importance Lengthening waiting lists for organ transplant mandates the development of strategies to expand the deceased donor pool. Due to concerns regarding organ viability, most organ donation organizations internationally wait no longer…
View article: Evaluating image quality in surgical photography: a multivariable analysis of cameras and shooting conditions
Evaluating image quality in surgical photography: a multivariable analysis of cameras and shooting conditions Open
Smartphones can produce high quality photographs. These findings should reassure clinicians that smartphone devices do not compromise photograph quality and support their use in clinical practice and image analysis research.
View article: Impact of donor transaminases on liver transplant utilisation and unnecessary organ discard: national registry cohort study
Impact of donor transaminases on liver transplant utilisation and unnecessary organ discard: national registry cohort study Open
Background Donor liver transaminases (ALT and AST) have been used to decline livers for transplant, despite evidence that they do not influence transplant outcomes. This study assesses the effect that raised donor transaminases have on the…
View article: Deep learning for automated boundary detection and segmentation in organ donation photography
Deep learning for automated boundary detection and segmentation in organ donation photography Open
Objectives Medical photography is ubiquitous and plays an increasingly important role in the fields of medicine and surgery. Any assessment of these photographs by computer vision algorithms requires first that the area of interest can acc…
View article: Simple tool implementing Bucher’s method for indirect treatment comparisons in meta-analyses
Simple tool implementing Bucher’s method for indirect treatment comparisons in meta-analyses Open
Healthcare practitioners and patients are often required to make choices between two treatment options which may have never been compared directly.When performing standard 'pairwise' meta-analysis, it is common to find trials comparing one…
View article: Robotic versus laparoscopic surgery for colorectal disease: a systematic review, meta-analysis and meta-regression of randomised controlled trials
Robotic versus laparoscopic surgery for colorectal disease: a systematic review, meta-analysis and meta-regression of randomised controlled trials Open
As experience in RS grows, evidence suggests an increasing safety profile for patients. Meta-regression revealed a significant temporal trend with complication rates favouring RS over LS. Heterogeneous reporting of complications hindered s…
View article: Robotic versus laparoscopic versus open nephrectomy for live kidney donors
Robotic versus laparoscopic versus open nephrectomy for live kidney donors Open
LDN is associated with less pain compared to ODN and has comparable pain to HALDN and RDN. HALDN is comparable to LDN in all outcomes except warm ischaemia time, which may be associated with a reduction. One study reported kidneys obtained…
View article: Uncertainty about how the early benefits of kidney transplant versus dialysis differ in ethnic minorities
Uncertainty about how the early benefits of kidney transplant versus dialysis differ in ethnic minorities Open
View article: BS O06 Robotic-assisted bariatric surgery: a systematic review on learning curves
BS O06 Robotic-assisted bariatric surgery: a systematic review on learning curves Open
Background Robotic-assisted minimally invasive surgery has improved patient outcomes and experiences in various surgical disciplines, demonstrating reduced complications, postoperative pain, and length of hospital stays. Within the field o…
View article: Computer image analysis with artificial intelligence: a practical introduction to convolutional neural networks for medical professionals
Computer image analysis with artificial intelligence: a practical introduction to convolutional neural networks for medical professionals Open
Artificial intelligence tools, particularly convolutional neural networks (CNNs), are transforming healthcare by enhancing predictive, diagnostic, and decision-making capabilities. This review provides an accessible and practical explanati…
View article: 180 Does Preoperative Cognitive Behavioural Therapy Improve Postoperative Weight Loss Outcomes in Patients Undergoing Bariatric Surgery? a Systematic Review and Meta-Analysis
180 Does Preoperative Cognitive Behavioural Therapy Improve Postoperative Weight Loss Outcomes in Patients Undergoing Bariatric Surgery? a Systematic Review and Meta-Analysis Open
Aim Bariatric surgery is an effective intervention in treating obesity. However, some patients experience weight regain or early weight stabilisation. It is thought that psychological comorbidity may contribute to this. We conducted a syst…
View article: 1258 Audit of Environmental Costs for Bariatric Face to Face Clinics: A Single Centre Study – Interim Findings
1258 Audit of Environmental Costs for Bariatric Face to Face Clinics: A Single Centre Study – Interim Findings Open
Aim The NHS has committed to delivering a net zero national health system by 2045. Patient travel accounts for approximately 20% of carbon footprint amongst resource use within outpatient appointments. The increased acceptability of digita…
View article: Frequency of Short- vs Long-Term Reporting of Bariatric Surgery Outcomes
Frequency of Short- vs Long-Term Reporting of Bariatric Surgery Outcomes Open
View article: 698 Frequency of Short vs Long-Term Reporting of Bariatric Surgery Outcomes
698 Frequency of Short vs Long-Term Reporting of Bariatric Surgery Outcomes Open
Bariatric surgery is an effective treatment for obesity. Though both short- and long-term outcomes have been reported, most of the published literature to date has focused on short-term outcomes. Identification of post-operative weight reg…