Gerald Bastian Schulz
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View article: Response to “Comment on ‘Peri‐operative outcomes of open, laparoscopic and robotic simple prostatectomy’”
Response to “Comment on ‘Peri‐operative outcomes of open, laparoscopic and robotic simple prostatectomy’” Open
View article: Association of interleukin-6 serum levels with local tumor stage and lymph node metastasis of urothelial carcinoma
Association of interleukin-6 serum levels with local tumor stage and lymph node metastasis of urothelial carcinoma Open
This prospective study found that elevated preoperative IL-6 serum levels correlated with local tumor stage and were associated with lymph node metastasis in UC patients undergoing RC. However, IL-6 levels were also elevated in patients wi…
View article: Peri‐operative outcomes of open, laparoscopic and robotic simple prostatectomy
Peri‐operative outcomes of open, laparoscopic and robotic simple prostatectomy Open
Objective To compare peri‐operative outcomes and trends in open (OSP), laparoscopic (LSP) and robot‐assisted simple prostatectomy (RASP). Materials and Methods We used German Nationwide Inpatient Data (GRAND), provided by the Research Data…
View article: Comparison of Perioperative Outcomes for Prostate Artery Embolization Versus Transurethral Resection of the Prostate and Laser Enucleation for Benign Prostatic Hyperplasia: Results from the GRAND Study
Comparison of Perioperative Outcomes for Prostate Artery Embolization Versus Transurethral Resection of the Prostate and Laser Enucleation for Benign Prostatic Hyperplasia: Results from the GRAND Study Open
Background/Objectives: Prostate artery embolization (PAE) has emerged as a relatively new, minimally invasive alternative for the treatment of benign prostatic hyperplasia. We aimed to compare the perioperative outcomes and trends of PAE v…
View article: The Epidemiology of Urinary Tract Trauma: Results from the GRAND Study.
The Epidemiology of Urinary Tract Trauma: Results from the GRAND Study. Open
Background: Urinary tract trauma encompasses injuries to the kidneys, ureters, urinary bladder, and urethra and can result from both external and iatrogenic causes. We aimed to evaluate the epidemiology, clinical characteristics, an…
View article: Expression Profiles of Co-Inhibitory Receptors in Non-Urothelial Bladder Cancer: Preclinical Evidence for the Next Generation of Immune Checkpoint Inhibitors
Expression Profiles of Co-Inhibitory Receptors in Non-Urothelial Bladder Cancer: Preclinical Evidence for the Next Generation of Immune Checkpoint Inhibitors Open
Immune checkpoint inhibition is a cornerstone of bladder cancer therapy, but its efficacy in non-urothelial subtypes of bladder cancer is limited, and the prognosis remains poor. Therefore, we investigated the potential of the immune check…
View article: Prevalence and Prognostic Significance of Preoperative Anemia in Radical Cystectomy Patients: A Multicenter Retrospective Observational Study
Prevalence and Prognostic Significance of Preoperative Anemia in Radical Cystectomy Patients: A Multicenter Retrospective Observational Study Open
View article: The perioperative outcomes of retroperitoneal lymph node dissection in Germany for patients with testicular cancer: Results from the <scp>GRAND</scp> study
The perioperative outcomes of retroperitoneal lymph node dissection in Germany for patients with testicular cancer: Results from the <span>GRAND</span> study Open
We aimed to assess the current trends and outcomes of retroperitoneal lymph node dissection (RPLND) in patients with testicular cancer in Germany, as well as to provide evidence on the role of the type of surgical approach, prior chemother…
View article: Radiomics-based differentiation of upper urinary tract urothelial and renal cell carcinoma in preoperative computed tomography datasets
Radiomics-based differentiation of upper urinary tract urothelial and renal cell carcinoma in preoperative computed tomography datasets Open
Background To investigate a non-invasive radiomics-based machine learning algorithm to differentiate upper urinary tract urothelial carcinoma (UTUC) from renal cell carcinoma (RCC) prior to surgical intervention. Methods Preoperative compu…
View article: Perioperative outcomes of HoLEP, ThuLEP, and TURP in patients with prostate cancer: results from the GRAND study
Perioperative outcomes of HoLEP, ThuLEP, and TURP in patients with prostate cancer: results from the GRAND study Open
Background Limited data exist on the role of holmium laser enucleation of the prostate (HoLEP), thulium laser enucleation of the prostate (ThuLEP), and transurethral resection of the prostate (TURP) in patients with prostate cancer (PCa). …
View article: The Prognostic Value of Perioperative Factors on Biochemical Recurrence in Patients Undergoing Radical Prostatectomy
The Prognostic Value of Perioperative Factors on Biochemical Recurrence in Patients Undergoing Radical Prostatectomy Open
Locally advanced PC, positive surgical margins, and worse ISUP grade are independent risk factors for BCR. Accordingly, patients at BCR high-risk based on the EAU risk stratification present worse overall survival.
View article: 68Ga-FAPI and 18F-FAPI PET/CT for detection of nodal metastases prior radical cystectomy in high-risk urothelial carcinoma patients
68Ga-FAPI and 18F-FAPI PET/CT for detection of nodal metastases prior radical cystectomy in high-risk urothelial carcinoma patients Open
Introduction To determine the best therapeutic strategy for muscle-invasive bladder cancer (BC), the accuracy of lymph node staging is of paramount importance. However, diagnostic performance of conventional computed tomography in BC prior…
View article: Perioperative complications of focal therapy for prostate cancer: results from the GeRmAn Nationwide inpatient Data ( <scp>GRAND)</scp> study
Perioperative complications of focal therapy for prostate cancer: results from the GeRmAn Nationwide inpatient Data ( <span>GRAND)</span> study Open
Objective To compare the perioperative complications of the most common focal therapy (FT) modalities for prostate cancer. Patients and Methods We assessed the GeRmAn Nationwide inpatient Data (GRAND) from 2005 to 2023, provided by the Res…
View article: Prognostic impact of combined loss of RB1, p53 and p21 in muscle-invasive bladder cancer
Prognostic impact of combined loss of RB1, p53 and p21 in muscle-invasive bladder cancer Open
RB1, p53, and p21 are insufficient as single prognostic markers in MIBC but demonstrate significant prognostic relevance when analyzed in combination. These findings underscore the need for multi-marker approaches in prognostic modeling an…
View article: The Role of Salvage Cystectomy After Prior Trimodality Therapy: A Multinational Match-paired Analysis
The Role of Salvage Cystectomy After Prior Trimodality Therapy: A Multinational Match-paired Analysis Open
Salvage RC after TMT and primary RC have comparable perioperative outcomes. Patients undergoing salvage RC after TMT may have worse overall survival in the long term, likely reflecting tumor biology.
View article: Perioperative Outcomes After Radical Nephrectomy with Inferior Vena Cava Thrombectomy
Perioperative Outcomes After Radical Nephrectomy with Inferior Vena Cava Thrombectomy Open
Background and Objective: We aimed to evaluate current trends and complications after radical nephrectomy with inferior vena cava (IVC) thrombectomy and to provide evidence on the role of the annual hospital caseload on perioperative outco…
View article: Perioperative Outcomes and Trends of Surgical Correction of Male Urethral Strictures: Results from the GRAND Study
Perioperative Outcomes and Trends of Surgical Correction of Male Urethral Strictures: Results from the GRAND Study Open
Background: While various techniques for the surgical correction of urethral strictures exist, data on their trends and perioperative outcomes are limited. Methods: Data from the German Nationwide Inpatient Data (GRAND) registry (2005–2023…
View article: Spatial Expression of HER2, NECTIN4, and TROP-2 in Muscle-Invasive Bladder Cancer and Metastases: Implications for Pathological and Clinical Management
Spatial Expression of HER2, NECTIN4, and TROP-2 in Muscle-Invasive Bladder Cancer and Metastases: Implications for Pathological and Clinical Management Open
Muscle-invasive bladder cancer (MIBC) presents significant treatment challenges. Antibody-drug conjugates targeting human epidermal growth factor receptor 2 (HER2), trophoblast cell surface antigen 2 (TROP-2), and nectin cell adhesion mole…
View article: Discrepancies between physician-assessed and patient-reported complications after cystectomy – a prospective analysis
Discrepancies between physician-assessed and patient-reported complications after cystectomy – a prospective analysis Open
View article: Prophylactic Use of Biologic Mesh in Ileal Conduit (PUBMIC trial)
Prophylactic Use of Biologic Mesh in Ileal Conduit (PUBMIC trial) Open
View article: Radical Cystectomy with Ileal Orthotopic Neobladder after 70 Years Leads to Worse Health-Related Quality of Life
Radical Cystectomy with Ileal Orthotopic Neobladder after 70 Years Leads to Worse Health-Related Quality of Life Open
Background: Radical cystectomy (RC) with the formation of an ileal orthotopic neobladder (ONB) may adversely affect long-term health-related quality of life (HRQOL). An advanced age at the time of ONB construction could further exacerbate …
View article: Effects of Intraoperative Opioid Use and a Combined Anesthesia Protocol in Patients Undergoing Radical Cystectomy for Urothelial Carcinoma of the Bladder—A Single-Center Experience
Effects of Intraoperative Opioid Use and a Combined Anesthesia Protocol in Patients Undergoing Radical Cystectomy for Urothelial Carcinoma of the Bladder—A Single-Center Experience Open
Background: An increased intraoperative opioid dose seems to lead to worse outcomes in several types of cancer. We assessed the effect of intraoperatively administered opioids as well as the type of anesthesia on survival, recurrence rates…
View article: Response to Comment on Trends and outcomes of hospitalized patients with priapism in Germany: results from the GRAND study
Response to Comment on Trends and outcomes of hospitalized patients with priapism in Germany: results from the GRAND study Open
View article: Evolution of Robotic Urology in Clinical Practice from the Beginning to Now: Results from the GRAND Study Register
Evolution of Robotic Urology in Clinical Practice from the Beginning to Now: Results from the GRAND Study Register Open
Patients selected for robotic surgery in Germany presented better perioperative outcomes compared to those operated with an open approach.
View article: Thromboprophylaxis during neoadjuvant chemotherapy for bladder cancer reduces thromboembolism and bleeding
Thromboprophylaxis during neoadjuvant chemotherapy for bladder cancer reduces thromboembolism and bleeding Open
Objectives To assess the risk of venous thromboembolic events (VTEs) and bleeding with or without thromboprophylaxis during neoadjuvant chemotherapy in bladder cancer patients scheduled for radical cystectomy. Materials and Methods We cond…
View article: Toxicity-Induced Discontinuation of Immune Checkpoint Inhibitors in Metastatic Urothelial Cancer: 6-Year Experience from a Specialized Uro-Oncology Center
Toxicity-Induced Discontinuation of Immune Checkpoint Inhibitors in Metastatic Urothelial Cancer: 6-Year Experience from a Specialized Uro-Oncology Center Open
Immune checkpoint inhibitor (ICI) therapies have been established as the standard-of-care in various uro-oncological cancers. Immune-related adverse events (irAEs) are frequent, but their degree rarely leads to the discontinuation of immun…
View article: Perioperative Outcomes and Trends in Transurethral Resection of Bladder Tumors with Photodynamic Diagnosis: Results from the GeRmAn Nationwide Inpatient Data Study
Perioperative Outcomes and Trends in Transurethral Resection of Bladder Tumors with Photodynamic Diagnosis: Results from the GeRmAn Nationwide Inpatient Data Study Open
Background: Photodynamic diagnosis (PDD) during transurethral resection of bladder tumor (TURBT) is guideline recommended, as it improves bladder cancer detection rates. However, the extent to which PDD is implemented in everyday clinical …
View article: Trends and outcomes of hospitalized patients with priapism in Germany: results from the GRAND study
Trends and outcomes of hospitalized patients with priapism in Germany: results from the GRAND study Open
We aimed to provide evidence on the trends and in-hospital outcomes of patients with low- and high-flow priapism through the largest study in the field. We used the GeRmAn Nationwide inpatient Data (GRAND), provided by the Research Data Ce…
View article: The impact of health care on outcomes of suspected testicular torsion: results from the GRAND study
The impact of health care on outcomes of suspected testicular torsion: results from the GRAND study Open
Background Suspicion of testicular torsion represents a urological emergency, necessitating immediate surgery. Comprehensive data on the current trends and perioperative outcomes regarding surgical exploration are sparse. Therefore, we uti…
View article: The Vanishing Clinical Value of PD-L1 Status as a Predictive Biomarker in the First-Line Treatment of Urothelial Carcinoma of the Bladder
The Vanishing Clinical Value of PD-L1 Status as a Predictive Biomarker in the First-Line Treatment of Urothelial Carcinoma of the Bladder Open
Background: Our study endeavors to elucidate the clinical implications of PD-L1 positivity in individuals afflicted with advanced urothelial carcinoma of the bladder (UCB). Methods: Patients with advanced UCB were prospectively enrolled fo…