Gerardo Fernández
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View article: Prospective Evaluation of the Impact of Sedation During LAAO on Cognitive Function Using Oculomotor Biomarkers
Prospective Evaluation of the Impact of Sedation During LAAO on Cognitive Function Using Oculomotor Biomarkers Open
View article: External validation of precisebreast, a digital prognostic test for predicting breast cancer recurrence, in an early-stage cohort from the Netherlands
External validation of precisebreast, a digital prognostic test for predicting breast cancer recurrence, in an early-stage cohort from the Netherlands Open
View article: PreciseBreast is prognostic for breast cancer recurrence in a 21-gene assay managed cohort
PreciseBreast is prognostic for breast cancer recurrence in a 21-gene assay managed cohort Open
PreciseBreast (PDxBR) is an AI-based digital test that provides individualized risk prediction for invasive breast carcinoma (IBC) independent of a gene expression test and yields important prognostic information that may well guide decisi…
View article: Oculomotor behaviors during visual short-term memory binding in healthy aging
Oculomotor behaviors during visual short-term memory binding in healthy aging Open
The Visual Short-Term Memory Binding Task (VSTMBT) assesses the cognitive ability responsible for integrating and retaining objects' features on a temporary basis. The VSTMBT, combined with eye-tracking (ET), identified impairments in olde…
View article: Pie Diabético: una revisión actual del diagnóstico y tratamiento
Pie Diabético: una revisión actual del diagnóstico y tratamiento Open
El Pie Diabético es la complicación de Diabetes Mellitus que necesita seguimiento exhaustivo por médicos y enfermeros, así como cambios actitudinales de pacientes, familiares y personal de cuidado diario. El objetivo es Conocer los criteri…
View article: Eye movements powered by artificial intelligence identify asymptomatic carriers of familial Alzheimer’s disease
Eye movements powered by artificial intelligence identify asymptomatic carriers of familial Alzheimer’s disease Open
Eye-tracking (ET) metrics obtained during the Visual Short-Term Memory Binding Task (VSTMBT) have shown promise in detecting early and subtle alterations in individuals at risk for, or diagnosed with, Alzheimer’s disease (AD) dementia. How…
View article: Comparison of single-step methods for genomic prediction of age at first calving in dairy buffaloes
Comparison of single-step methods for genomic prediction of age at first calving in dairy buffaloes Open
The age at first calving (AFC) is an important trait to be considered in breeding programmes of dairy buffaloes, where new approaches and technologies, such as genomic selection, are constantly applied. Thus, the objective of this study wa…
View article: Abnormal eye movements increase as motor disabilities and cognitive impairments become more evident in Multiple Sclerosis: A novel eye-tracking study
Abnormal eye movements increase as motor disabilities and cognitive impairments become more evident in Multiple Sclerosis: A novel eye-tracking study Open
Background Eye movements can reflect brain alterations and inform on the presence of motor disabilities and cognitive impairments in people with multiple sclerosis (pwMS). Objective The aim of the study was to determine the correlation bet…
View article: Different correlates of memory decline in Alzheimer’s diseases and Frontotemporal dementia: evidence from a novel digital biomarker
Different correlates of memory decline in Alzheimer’s diseases and Frontotemporal dementia: evidence from a novel digital biomarker Open
Background Oculomotor behaviours (i.e., eye tracking ‐ ET) linked to cognitive performance can differentiate between the trajectories of neurodegeneration that lead to the Alzheimer’s disease Syndrome (ADS) or Fronto‐temporal Dementia (FTD…
View article: Changes in oculo‐motor activity during a cognitive challenge can distinguish clinical stages of early Alzheimer’s disease
Changes in oculo‐motor activity during a cognitive challenge can distinguish clinical stages of early Alzheimer’s disease Open
Background The eye adapts to the demands of our behavior [1], its motor activity has proven to be a feasible method for measuring cognition in both health and disease [2]. This study assessed the sensitivity of oculo‐motor features in a be…
View article: EPIDEMIOLOGÍA Y NUEVAS DIANAS MOLECULARES EN CÁNCER DE MAMA
EPIDEMIOLOGÍA Y NUEVAS DIANAS MOLECULARES EN CÁNCER DE MAMA Open
Introducción: El cáncer de mama constituye la primera causa de morbimortalidad por cáncer en la mujer a nivel mundial. Ecuador tampoco escapa a este problema de salud donde las muertes por cáncer de mama superan a otras neoplasias en la mu…
View article: Development and validation of an AI-enabled digital breast cancer assay to predict early-stage breast cancer recurrence within 6 years
Development and validation of an AI-enabled digital breast cancer assay to predict early-stage breast cancer recurrence within 6 years Open
View article: Contes o bajanades? El llibre per a infants al primer terç del segle XX
Contes o bajanades? El llibre per a infants al primer terç del segle XX Open
El primer terç del segle xx va tenir un significat especial per a la producció de la literatura infantil. Amb el terme poc políticament correcte de bajanades, inspirat en com titllava la literatura infantil l’escriptor Carles Riba, es pret…
View article: Estado de salud mental en madres de recién nacidos ingresados en el servicio de neonatología
Estado de salud mental en madres de recién nacidos ingresados en el servicio de neonatología Open
Introducción: las alteraciones de la salud mental en el periodo de puerperio presentan una alta morbilidad en las madres de los recién nacidos hospitalizados constituyendo un importante problema de salud pública. Objetivo: evaluar el estad…
View article: Salud mental en los estudiantes de la carrera de enfermería durante la pandemia COVID-19
Salud mental en los estudiantes de la carrera de enfermería durante la pandemia COVID-19 Open
Desde el inicio de la pandemia por el COVID-19, en las universidades se inició una nueva modalidad, ya que se impartieron las clases de manera virtual. Esto causó efectos negativos para la salud mental en los estudiantes de la carrera de e…
View article: Estrategias de intervención de los padres de niños asmáticos con modelos anatómicos educativos
Estrategias de intervención de los padres de niños asmáticos con modelos anatómicos educativos Open
Introducción: El asma infantil es una enfermedad crónica reversible, que se puede controlar con una adecuada educación de los padres. Objetivo: realizar una intervención educativa que desarrolle un superaprendizaje para el control del asma…
View article: Description of the Method for Evaluating Digital Endpoints in Alzheimer Disease Study: Protocol for an Exploratory, Cross-sectional Study
Description of the Method for Evaluating Digital Endpoints in Alzheimer Disease Study: Protocol for an Exploratory, Cross-sectional Study Open
Background More sensitive and less burdensome efficacy end points are urgently needed to improve the effectiveness of clinical drug development for Alzheimer disease (AD). Although conventional end points lack sensitivity, digital technolo…
View article: Oculomotor Abnormalities during Reading in the Offspring of Late-OnsetAlzheimer’s Disease
Oculomotor Abnormalities during Reading in the Offspring of Late-OnsetAlzheimer’s Disease Open
Introduction: Eye movement patterns during reading are well defined and documented. Each eye movement ends up in a fixation point, which allows the brain to process the incoming information and program the following saccade. In this work, …
View article: Memory‐driven eye movements prospectively predict dementia in people at risk of Alzheimer's disease
Memory‐driven eye movements prospectively predict dementia in people at risk of Alzheimer's disease Open
Introduction Oculomotor behaviors linked to cognitive performance revealed neurocognitive features of Alzheimer's disease (AD) that can enhance the accuracy of its assessment and diagnosis. Methods A sample of 107 participants (i.e., 65 mi…
View article: Additional file 1 of Antemortem detection of Parkinson’s disease pathology in peripheral biopsies using artificial intelligence
Additional file 1 of Antemortem detection of Parkinson’s disease pathology in peripheral biopsies using artificial intelligence Open
Additional file 1: Supplementary tables.
View article: Screening peripheral biopsies for alpha‐synuclein pathology using deep machine learning
Screening peripheral biopsies for alpha‐synuclein pathology using deep machine learning Open
Background Post‐mortem assessment remains the only option and a gold standard for a definitive diagnosis of Parkinson’s disease (PD). The antemortem diagnosis is challenging due to a variable clinical presentation and the abundance of mimi…
View article: A novel peripheral biomarker for mild cognitive impairment and Alzheimer’s disease
A novel peripheral biomarker for mild cognitive impairment and Alzheimer’s disease Open
Background Recent evidence suggests that oculomotor behaviours linked to cognitive performance can be a biomarker of Alzheimer’s disease (AD). Short‐Term Memory Binding (STMB) declines in patients with AD dementia and in those at risk of d…
View article: Tracking the involuntary retrieval of unwanted memory in the human brain with functional MRI
Tracking the involuntary retrieval of unwanted memory in the human brain with functional MRI Open
This study is a two-session fMRI experiment, with the 24 hours interval between two sessions. Day1 session consists of the familiarization phase, the study phase, and the immediate typing test. The Day2 session consists of the second typin…
View article: Adiponectina, esteatosis hepática y la prevención de la obesidad infantil
Adiponectina, esteatosis hepática y la prevención de la obesidad infantil Open
La obesidad esta caracterizada fenotipicamente por una acumulacion de tejido adiposo anormal o excesivo, que determina un estado inflamatorio de bajo grado, con un aumento de las concentraciones circulantes de citoquinas inflamatorias y pr…
View article: P2‐259: OCULOMOTOR RESPONSES LINKED TO COGNITIVE MARKERS FOR ALZHEIMER'S DISEASE CAN ENHANCE RISK PROFILING IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT
P2‐259: OCULOMOTOR RESPONSES LINKED TO COGNITIVE MARKERS FOR ALZHEIMER'S DISEASE CAN ENHANCE RISK PROFILING IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT Open
Combining eye-tracking methodologies with a cognitive marker for Alzheimer's disease, namely the Short-Term Memory Binding Test (STMBT), has enhanced the effectiveness of the assessment increasing its sensitivity and specificity to 100%. W…
View article: Increased serum ferritin and interleukin-18 levels in children with dengue
Increased serum ferritin and interleukin-18 levels in children with dengue Open
View article: Mycobacterium Tuberculosis Infection: Participation of TH1, TH2, TH17 and Regulatory T Cells in the Immune Response
Mycobacterium Tuberculosis Infection: Participation of TH1, TH2, TH17 and Regulatory T Cells in the Immune Response Open
Mycobacterium tuberculosis, the etiologic agent of Tuberculosis, is a pathogen that is widely distributed geographically. Tuberculosis is classified as a granulomatous inflammatory condition where effector cells accumulate at the site of m…
View article: Movimientos oculares como herramienta de ayuda en el diagnóstico temprano del mal de Alzheimer
Movimientos oculares como herramienta de ayuda en el diagnóstico temprano del mal de Alzheimer Open
La lectura y la observación de imágenes conforman procesos cognitivos retroalimentados que requieren la integración de diferentes subsistemas (memoria, atención, acción) y por consiguiente constituyen actividades ideales para explorar las …
View article: Visual Processing during Short-Term Memory Binding in Mild Alzheimer’s Disease
Visual Processing during Short-Term Memory Binding in Mild Alzheimer’s Disease Open
Patients with Alzheimer's disease (AD) typically present with attentional and oculomotor abnormalities that can have an impact on visual processing and associated cognitive functions. Over the last few years, we have witnessed a shift towa…
View article: Procesamiento de las expresiones faciales en personas con esquizofrenia, Análisis dinámico de la información visual
Procesamiento de las expresiones faciales en personas con esquizofrenia, Análisis dinámico de la información visual Open
Las personas con esquizofrenia presentan deficiencias en su desempeño social. El procesamiento emocional explica los aspectos relacionados con percibir y utilizar emociones faciales para un adecuado manejo social. Los movimientos oculares …