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Microwave-Assisted Neutral Glycosylation Reactions in the Absence of Reagent Activators Open
Use of a microwave-labile leaving group, 2,4-dinitrophenyl (2,4-DNP), leads to O-glycosylation in 70–80% yields with high α-selectivity. The 2,4-DNP glycosyl donors, protected with electron-donating benzyl ethers, gave the best results und…
The Glycopeptide PV-PS A1 Immunogen Elicits Both CD4+ and CD8+ Responses Open
Background/Objectives: The MHCII-dependent, CD4+ T-cell zwitterionic polysaccharide PS A1 has been investigated as a promising carrier for vaccine development because it can induce an MHCII-dependent CD4+ response towards a variety of tumo…