Gerben Stege
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View article: Strengths and challenges in current lung cancer care: Timeliness and diagnostic procedures in six Dutch hospitals
Strengths and challenges in current lung cancer care: Timeliness and diagnostic procedures in six Dutch hospitals Open
These insights could aid in improved LC diagnostics and efficient implementation of new techniques like liquid biopsy and artificial intelligence. This may lead to more timely LC care, a decreased number of invasive procedures, less variab…
View article: Liquid biopsy-based decision support algorithms for diagnosis and subtyping of lung cancer
Liquid biopsy-based decision support algorithms for diagnosis and subtyping of lung cancer Open
In patients suspected of LC, the LBx-based decision-support algorithms allowed identification of about two-thirds of all LC and NSCLC patients and half of SCLC patients. These models therefore show clinical value and may support LC diagnos…
View article: Circulating biomarkers for monitoring therapy response and detection of disease progression in lung cancer patients
Circulating biomarkers for monitoring therapy response and detection of disease progression in lung cancer patients Open
Liquid biopsies have become of interest as minimally invasive ways to monitor treatment response in lung cancer patients. Circulating tumor DNA (ctDNA) and protein biomarkers are evaluated for their added value in monitoring therapy respon…
View article: Pragmatic trial on inhaled corticosteroid withdrawal in patients with COPD in general practice
Pragmatic trial on inhaled corticosteroid withdrawal in patients with COPD in general practice Open
The therapeutic value of inhaled corticosteroids (ICSs) for COPD is limited. In published RCTs, ICS could be withdrawn in COPD patients without increasing exacerbation risk when bronchodilator treatment is optimized. Here we report on the …
View article: Prospective cohort study of patients with advanced cancer and their relatives on the experienced quality of care and life (eQuiPe study): a study protocol
Prospective cohort study of patients with advanced cancer and their relatives on the experienced quality of care and life (eQuiPe study): a study protocol Open
Background Palliative care is becoming increasingly important because the number of patients with an incurable disease is growing and their survival is improving. Previous research tells us that early palliative care has the potential to i…
View article: Correction of the NSE concentration in hemolyzed serum samples improves its diagnostic accuracy in small-cell lung cancer
Correction of the NSE concentration in hemolyzed serum samples improves its diagnostic accuracy in small-cell lung cancer Open
Neuron-specific enolase (NSE) is a well-known biomarker for the diagnosis, prognosis and treatment monitoring of small-cell lung cancer (SCLC). Nevertheless, its clinical applicability is limited since serum NSE levels are influenced by he…