Germán Chiarelli
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View article: Super-resolution imaging in whole cells and tissues via DNA-PAINT on a spinning disk confocal with optical photon reassignment
Super-resolution imaging in whole cells and tissues via DNA-PAINT on a spinning disk confocal with optical photon reassignment Open
Single-Molecule Localization Microscopy (SMLM) has traditionally faced challenges to optimize signal-to-noise ratio, penetration depth, field-of-view (FOV), and spatial resolution simultaneously. Here, we show that DNA-PAINT imaging on a S…
View article: Label-free (fluorescence-free) sensing of a single DNA molecule on DNA origami using a plasmon-enhanced WGM sensor
Label-free (fluorescence-free) sensing of a single DNA molecule on DNA origami using a plasmon-enhanced WGM sensor Open
The integration of DNA origami structures with opto-plasmonic whispering gallery mode (WGM) sensors offers a significant advancement in label-free biosensing, overcoming the limitations of traditional fluorescence-based techniques, and pro…
View article: Super-resolution imaging in whole cells and tissues via DNA-PAINT on a spinning disk confocal with optical photon reassignment
Super-resolution imaging in whole cells and tissues via DNA-PAINT on a spinning disk confocal with optical photon reassignment Open
Single Molecule Localization Microscopy (SMLM) has traditionally faced challenges to optimize signal-to-noise ratio, penetration depth, field-of-view (FOV), and spatial resolution simultaneously. Here, we show that DNA-PAINT imaging on a S…
View article: Universal click-chemistry approach for the DNA functionalization of nanoparticles
Universal click-chemistry approach for the DNA functionalization of nanoparticles Open
Nanotechnology has revolutionized the fabrication of hybrid species with tailored functionalities. A milestone in this field is the DNA conjugation of nanoparticles, introduced almost 30 years ago, which typically exploits the affinity bet…
View article: Ultransensitive and multiplexed miRNA detection system with DNA-PAINT
Ultransensitive and multiplexed miRNA detection system with DNA-PAINT Open
This upload contains the publication entitled "Ultrasensitive and multiplexed miRNA detection system with DNA-PAINT" and the related supporting information published in Biosensors and Bioelectronics (Elsevier) on 30 December 2023.
View article: Super-Resolved FRET Imaging by Confocal Fluorescence-Lifetime Single-Molecule Localization Microscopy
Super-Resolved FRET Imaging by Confocal Fluorescence-Lifetime Single-Molecule Localization Microscopy Open
FRET-based methods are a special tool for detecting interactions between (bio)molecules and their immediate environment. The spatial distribution of molecular interactions and functional states can be seen using FLIM (Fluorescence Lifetime…
View article: Super-Resolved FRET Imaging by Confocal Fluorescence-Lifetime Single-Molecule Localization Microscopy
Super-Resolved FRET Imaging by Confocal Fluorescence-Lifetime Single-Molecule Localization Microscopy Open
FRET-based methods are a special tool for detecting interactions between (bio)molecules and their immediate environment. The spatial distribution of molecular interactions and functional states can be seen using FLIM (Fluorescence Lifetime…
View article: Super‐Resolved FRET Imaging by Confocal Fluorescence‐Lifetime Single‐Molecule Localization Microscopy
Super‐Resolved FRET Imaging by Confocal Fluorescence‐Lifetime Single‐Molecule Localization Microscopy Open
Fluorescence Resonance Energy Transfer (FRET)‐based approaches are unique tools for sensing the immediate surroundings and interactions of (bio)molecules. FRET imaging and Fluorescence Lifetime Imaging Microscopy (FLIM) enable the visualiz…
View article: Ultrasensitive and multiplexed miRNA detection system with DNA-PAINT
Ultrasensitive and multiplexed miRNA detection system with DNA-PAINT Open
This dataset contains the raw data that were used for the publication entitled, "Ultrasensitive and multiplexed miRNA detection system with DNA-PAINT" published in Biosensors and Bioelectronics on 30 December 2023.
View article: Ultrasensitive and multiplexed miRNA detection system with DNA-PAINT
Ultrasensitive and multiplexed miRNA detection system with DNA-PAINT Open
This dataset contains the raw data that were used for the publication entitled, "Ultrasensitive and multiplexed miRNA detection system with DNA-PAINT" published in Biosensors and Bioelectronics on 30 December 2023.
View article: DNA Self-Assembly of Single Molecules with Deterministic Position and Orientation
DNA Self-Assembly of Single Molecules with Deterministic Position and Orientation Open
An ideal nanofabrication method should allow the organization of nanoparticles and molecules with nanometric positional precision, stoichiometric control, and well-defined orientation. The DNA origami technique has evolved into a highly ve…