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Minichromosome Maintenance Proteins: From DNA Replication to the DNA Damage Response Open

Agnes Malysa, Xiaohong Mary Zhang, Gerold Bepler · 2024

Biology

The DNA replication machinery is highly conserved from bacteria to eukaryotic cells. Faithful DNA replication is vital for cells to transmit accurate genetic information to the next generation. However, both internal and external DNA damag…

Acetylation of MLH1 by CBP increases cellular DNA mismatch repair activity Open

Mu Zhang, Jiawei Zhao, Peter M. Glazer, Wenlong Bai, Gerold Bepler , et al. · 2023

Biology Chemistry

The DNA mismatch repair (MMR) proteins recognize and repair DNA base pair mismatches and insertions/deletions of DNA that have occurred during DNA replication. Additionally, they are involved in regulation of the DNA damage response, inclu…

Supplemental Table 2 from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard G. Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine Computer science

Cloning primers.

Supplemental Figure 5 from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine

Specificity control of mouse immune serum.

Supplemental Figure 6 from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine

Specificity control of feline immune serum.

Supplemental Table 1 from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine Computer science

Feline mammary carcinoma patients.

Supplemental Figure 4 from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine

Q141K substitution in feline HER2.

Supplemental Figure 3 from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine

Sequence alignment of HER2 extracellular and transmembrane regions (ECTM) from 5 mammalian species.

Supplemental Figure 3 from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine

Sequence alignment of HER2 extracellular and transmembrane regions (ECTM) from 5 mammalian species.

Supplemental Figure 6 from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine

Specificity control of feline immune serum.

Supplemental Figure 4 from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine

Q141K substitution in feline HER2.

Supplemental Figure 1 from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine

Authentication of the cat mammary tumor lines K248 and K12 used in this study via short tandem repeat (STR) analysis at 4 loci.

Supplemental Figure 1 from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine

Authentication of the cat mammary tumor lines K248 and K12 used in this study via short tandem repeat (STR) analysis at 4 loci.

Supplemental Figure 5 from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine

Specificity control of mouse immune serum.

Supplemental Figure 2 from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine

RTK analysis of FMC primary tissue and cell lines.

Data from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine

Domestic cats share human living environments and genetic traits. They develop spontaneous feline mammary carcinoma (FMC) with similar histopathology to human breast cancer. HER2 and AKT phosphorylation was demonstrated in primary FMC by i…

Supplemental Figure 2 from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine

RTK analysis of FMC primary tissue and cell lines.

Supplemental Table 1 from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Computer science Medicine

Feline mammary carcinoma patients.

Data from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine

Domestic cats share human living environments and genetic traits. They develop spontaneous feline mammary carcinoma (FMC) with similar histopathology to human breast cancer. HER2 and AKT phosphorylation was demonstrated in primary FMC by i…

Supplemental Table 2 from Induction of HER2 Immunity in Outbred Domestic Cats by DNA Electrovaccination Open

Heather M. Gibson, Jesse Veenstra, Richard Jones, Ulka N. Vaishampayan, Michele Sauerbrey , et al. · 2023

Biology Medicine Computer science

Cloning primers.

Supplementary Tables 1-3. from <i>SMARCA4</i>/BRG1 Is a Novel Prognostic Biomarker Predictive of Cisplatin-Based Chemotherapy Outcomes in Resected Non–Small Cell Lung Cancer Open

Erica H. Bell, Arup R. Chakraborty, Xiaokui Mo, Ziyan Liu, Konstantin Shilo , et al. · 2023

Medicine Biology

Supplementary Table 1. Univariate analysis of SMARCA4 expression in the Director's Challenge Study. Supplementary Table 2. Log-rank analysis of SMARCA4 expression for observation vs adjuvant cisplatin/vinorelbine in NSCLC within the JBR.10…

Supplementary Data from Profiling the Mutational Landscape in Known Driver Genes and Novel Genes in African American Non–Small Cell Lung Cancer Patients Open

Christine M. Lusk, Donovan Watza, Greg Dyson, Douglas B. Craig, Valerie Ratliff , et al. · 2023

Biology Medicine Computer science

Table S7

Data from Profiling the Mutational Landscape in Known Driver Genes and Novel Genes in African American Non–Small Cell Lung Cancer Patients Open

Christine M. Lusk, Donovan Watza, Greg Dyson, Douglas B. Craig, Valerie Ratliff , et al. · 2023

Biology Medicine

Purpose:Identifying novel driver genes and mutations in African American non–small cell lung cancer (NSCLC) cases can inform targeted therapy and improve outcomes for this traditionally underrepresented population.Experimental Design:Tumor…

Data from High Expression of Mammalian Target of Rapamycin Is Associated with Better Outcome for Patients with Early Stage Lung Adenocarcinoma Open

Valsamo Anagnostou, Gerold Bepler, Konstantinos N. Syrigos, L.T. Tanoue, Scott Gettinger , et al. · 2023

Biology Medicine

Purpose: Mammalian target of rapamycin (mTOR) is a key kinase downstream of phosphoinositide 3-kinase (PI3K)/AKT predominantly involved in translational control in the presence of nutrients and energy. Despite the well known role of mTOR i…

Supplementary Data from Identification and Characterization of Synthetic Viability with ERCC1 Deficiency in Response to Interstrand Crosslinks in Lung Cancer Open

Joshua Heyza, Wen Lei, Donovan Watza, Hao Zhang, Wei Chen , et al. · 2023

Biology

Supplemental Figure S1. A. Clonogenic survival assays with cisplatin treatment in p53WT cell lines {plus minus} ERCC1. B. Clonogenic survival assays with cisplatin treatment in p53 null and p53mutant cell lines {plus minus} ERCC1. n = 3 in…

Supplementary Data from Profiling the Mutational Landscape in Known Driver Genes and Novel Genes in African American Non–Small Cell Lung Cancer Patients Open

Christine M. Lusk, Donovan Watza, Greg Dyson, Douglas B. Craig, Valerie Ratliff , et al. · 2023

Biology Medicine Computer science

Tables S1-S6 and Figures S1-S3.

Supplementary Data from Identification and Characterization of Synthetic Viability with ERCC1 Deficiency in Response to Interstrand Crosslinks in Lung Cancer Open

Joshua Heyza, Wen Lei, Donovan Watza, Hao Zhang, Wei Chen , et al. · 2023

Biology

Supplemental Figure S1. A. Clonogenic survival assays with cisplatin treatment in p53WT cell lines {plus minus} ERCC1. B. Clonogenic survival assays with cisplatin treatment in p53 null and p53mutant cell lines {plus minus} ERCC1. n = 3 in…

Supplementary Data from High Expression of Mammalian Target of Rapamycin Is Associated with Better Outcome for Patients with Early Stage Lung Adenocarcinoma Open

Valsamo Anagnostou, Gerold Bepler, Konstantinos N. Syrigos, L.T. Tanoue, Scott Gettinger , et al. · 2023

Medicine Biology Computer science

Supplementary Data from High Expression of Mammalian Target of Rapamycin Is Associated with Better Outcome for Patients with Early Stage Lung Adenocarcinoma

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