Geron A. Bindseil
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View article: O1‐02‐05: A novel positron emission tomography contrast agent targeting cathepsin d shows preferential <i>in vivo</i> retention in an Alzheimer's disease mouse model
O1‐02‐05: A novel positron emission tomography contrast agent targeting cathepsin d shows preferential <i>in vivo</i> retention in an Alzheimer's disease mouse model Open
Early detection of Alzheimer's disease (AD) pathology remains a serious challenge for both diagnosis and development of treatment. Cathepsin D (CatD), a lysosomal aspartyl protease, is over-expressed in AD and therefore is a potential biom…