Explanipedia

Motile microfilaria captured by fluorescent microscopy and the unmasking of eosinophilia following treatment Open

Gerrit Kann, Hermann Juling, Valentina Ilievski, Gerrit Burger, Stephan Göttig , et al. · 2023

A 24-year-old patient from Cameroon presented to our hospital because of a foreign structure in her left eye. To our knowledge, for the first time, fluorescent microscopy revealed motile microfilariae, and the diagnosis of loiasis was esta…

HIV-1 Infection of Long-Lived Hematopoietic Precursors In Vitro and In Vivo Open

Sebastian Renelt, Patrizia Schult-Dietrich, Hanna‐Mari Baldauf, Stefan Stein, Gerrit Kann , et al. · 2022

Latent reservoirs in human-immunodeficiency-virus-1 (HIV-1)-infected individuals represent a major obstacle in finding a cure for HIV-1. Hematopoietic stem and progenitor cells (HSPCs) have been described as potential HIV-1 targets, but th…

Evaluation of Platelet Activation by HIV Protease Inhibitors – The HIV-PLA II Study Open

Gerrit Kann, Junaid Owasil, Karina Kuczka, A Haberl, Timo Wolf , et al. · 2021

Gerrit Kann,1,* Junaid Owasil,1,* Karina Kuczka,2 Annette Haberl,1 Timo Wolf,1 Pavel Khaykin,1 Sebastian Harder,2 Christoph Stephan,1 Nils von Hentig1 1HIVCENTER, Medical HIV Treatment and Research Unit, Johann Wolfgang Goethe University F…

Evaluation of Platelet Activation by HIV Protease Inhibitors – The HIV-PLA II Study Open

Gerrit Kann, Junaid Owasil, Karina Kuczka, Annette Haberl, Timo Wolf , et al. · 2021

DRKS00000288.

Disseminated disease due to non-tuberculous mycobacteria in HIV positive patients: A retrospective case control study Open

Nils Wetzstein, Ari Geil, Gerrit Kann, Annette Lehn, Gundolf Schüttfort , et al. · 2021

Introduction Disseminated infection due to non-tuberculous mycobacteria has been a major factor of mortality and comorbidity in HIV patients. Until 2018, U.S. American guidelines have recommended antimycobacterial prophylaxis in patients w…

Outcomes of cardiovascular magnetic resonance imaging in people living with HIV Open

Christophe Arendt, Philipp de Leuw, A Haberl, Gerrit Kann, Timo Wolf , et al. · 2021

Funding Acknowledgements Type of funding sources: None. Background/Introduction People living with human immunodeficiency virus (HIV, PLWH) are at increased risk of cardiovascular disease (CVD). HIV infection and accelerated traditional ri…

Myocardial Fibrosis and Inflammation by CMR Predict Cardiovascular Outcome in People Living With HIV Open

Philipp de Leuw, Christophe Arendt, Annette E. Haberl, Daniel Froadinadl, Gerrit Kann , et al. · 2021

Our findings reveal important prognostic associations of diffuse myocardial fibrosis and LV remodeling in PLWH. These results may support development of personalized approaches to screening and early intervention to reduce the burden of HF…

Antiretroviral treatment outcomes among late HIV presenters initiating treatment with integrase inhibitors or protease inhibitors Open

Gundolf Schuettfort, L Boekenkamp, Alfonso Cabello, AG Cotter, Philipp de Leuw , et al. · 2020

Objectives The aim of the study was to investigate the efficacy and safety of first‐line antiretroviral therapy (ART) with integrase inhibitor (INI) or protease inhibitor (PI)‐based regimens in patients with low CD4 cell counts and/or an A…

Evidence of SARS-CoV-2 Infection in Returning Travelers from Wuhan, China Open

Sebastian Hoehl, Holger F. Rabenau, Annemarie Berger, Marhild Kortenbusch, Jindřich Činátl , et al. · 2020

S.1278-1280

Clinical characteristics in a sentinel case as well as in a cluster of tularemia patients associated with grape harvest Open

Nils Wetzstein, Iris Kärcher, Claus P. Küpper-Tetzel, Gerrit Kann, Michael Hogardt , et al. · 2019

New Lineage of Lassa Virus, Togo, 2016 Open

Shannon Whitmer, Thomas Strecker, Dániel Cadar, Hans‐Peter Dienes, Kelly Faber , et al. · 2018

We describe a strain of Lassa virus representing a putative new lineage that was isolated from a cluster of human infections with an epidemiologic link to Togo. This finding extends the known range of Lassa virus to Togo.

Favipiravir and Ribavirin Treatment of Epidemiologically Linked Cases of Lassa Fever Open

Vanessa Raabe, Gerrit Kann, Bruce S. Ribner, Andrés Morales, Jay B. Varkey , et al. · 2017

Two patients with Lassa fever are described who are the first human cases treated with a combination of ribavirin and favipiravir. Both patients survived but developed transaminitis and had prolonged detectable virus RNA in blood and semen…

Complete Genome Sequence of an Ebola Virus Isolate Imported from Sierra Leone to Germany Determined by Circle Sequencing Open

Jan Philipp Mengel, Artur Lissin, Nadine Biedenkopf, Tilman Schultze, Gopala Krishna Mannala , et al. · 2016

We report here a complete genome sequence of Ebola virus Makona from a nonfatal patient sample that originated in Sierra Leone during the last Ebola virus outbreak in West Africa (species Zaire ebolavirus ) using a highly accurate circle s…

Genome Sequence of Lassa Virus Isolated from the First Domestically Acquired Case in Germany Open

Svenja Wolff, Tilman Schultze, Sarah Katharina Fehling, Jan Philipp Mengel, Gerrit Kann , et al. · 2016

Lassa virus (LASV) is a zoonotic, hemorrhagic fever-causing virus endemic in West Africa, for which no approved vaccines or specific treatment options exist. Here, we report the genome sequence of LASV isolated from the first case of acqui…

Commentary: Management of Microbiological Samples in a Confirmed Case of Ebola Virus Disease: Constraints and Limitations Open

Michael Hogardt, Timo Wolf, Gerrit Kann, Hans‐Reinhard Brodt, Christian Brandt , et al. · 2015

In light of the recent Ebola virus outbreak, it has to be realized that besides medical treatment, precise algorithms for the management of complicating microbial infections are mandatory for Ebola virus disease (EVD) patients. While the n…

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