Gianfranco Gigliucci
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View article: Early Osteoarthritis Questionnaire (EOAQ): a tool to assess knee osteoarthritis at initial stage
Early Osteoarthritis Questionnaire (EOAQ): a tool to assess knee osteoarthritis at initial stage Open
Background: Early stage of osteoarthritis (OA) is characterized by joint stiffness and pain as well as by subclinical structural changes that may affect cartilage, synovium, and bone. At the moment, the lack of a validated definition of ea…
View article: Impact of Covid-19 pandemic on injection-based practice: report from an Italian multicenter and multidisciplinary survey.
Impact of Covid-19 pandemic on injection-based practice: report from an Italian multicenter and multidisciplinary survey. Open
The reported decrease of the injection-based practice in our country during the COVID-19 pandemic highlights the detrimental effects of the COVID-19 pandemic on the management of chronic musculoskeletal diseases with possible negative cons…
View article: Hepatitis B (HBV) reactivation in patients receiving biologic therapy for chronic inflammatory diseases in clinical practice.
Hepatitis B (HBV) reactivation in patients receiving biologic therapy for chronic inflammatory diseases in clinical practice. Open
Data of our study highlight that guidelines on management of HBV patients treated with biologic therapies should be still implemented in clinical practice when considering that, although infrequent, HBV reactivation could be potentially li…
View article: Systematic Literature Review and Expert Opinion for the Use of Viscosupplementation with Hyaluronic Acid in Different Localizations of Osteoarthritis
Systematic Literature Review and Expert Opinion for the Use of Viscosupplementation with Hyaluronic Acid in Different Localizations of Osteoarthritis Open
Osteoarthritis (OA) is a significant cause of disability. Considering the increasing diffusion of the viscosupplementation (VS) with hyaluronic acid (HA), the International Symposium Intra Articular Treatment (ISIAT) appointed a Technical …
View article: Intradermal Vaccination: A Potential Tool in the Battle Against the COVID-19 Pandemic?
Intradermal Vaccination: A Potential Tool in the Battle Against the COVID-19 Pandemic? Open
This narrative review is the final output of an initiative of the SIM (Italian Society of Mesotherapy). A narrative review of scientific literature on the efficacy of fractional intradermal vaccination in comparison with full doses has bee…
View article: Cross Cultural Adaptation and Validation of Italian Version of the Leeds Assessment of Neuropathic Symptoms and Signs Scale and Pain DETECT Questionnaire for the Distinction between Nociceptive and Neuropathic Pain
Cross Cultural Adaptation and Validation of Italian Version of the Leeds Assessment of Neuropathic Symptoms and Signs Scale and Pain DETECT Questionnaire for the Distinction between Nociceptive and Neuropathic Pain Open
Objective. This study aimed to validate Italian versions of Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) scale and Pain DETECT questionnaire (PD-Q) and evaluate the ability of these questionnaires to discriminate between noci…
View article: Differences in biologics for treating ankylosing spondylitis: the contribution of network meta-analysis.
Differences in biologics for treating ankylosing spondylitis: the contribution of network meta-analysis. Open
Results from NMA on the use of biologics in AS indicates infliximab emerged as the drug with the highest probability of obtaining ASAS20 response both at 12 and 24 weeks of treatment.
View article: The evidence of surgery delay after viscosupplementation is increasing
The evidence of surgery delay after viscosupplementation is increasing Open
Osteoarthritis (OA) is a widespread disease throughout the world and prosthetic replacement is considered an effective and definitive treatment. However, some patients do not want or cannot undergo this type of invasive procedure due to th…
View article: <p>Efficacy of a Single Intra-Articular HYMOVIS ONE Injection for Managing Symptomatic Hip Osteoarthritis: A 12-Month Follow-Up Retrospective Analysis of the ANTIAGE Register Data</p>
Efficacy of a Single Intra-Articular HYMOVIS ONE Injection for Managing Symptomatic Hip Osteoarthritis: A 12-Month Follow-Up Retrospective Analysis of the ANTIAGE Register Data Open
Our study supports the clinical efficacy and safety of a single HYMOVIS ONE injection for managing symptoms in patients with hip OA, confirming previous data on the use of HYMOVIS as a background therapy in the management of knee osteoarth…
View article: A review of network meta-analysis comparing biologics in the treatment of rheumatoid arthritis.
A review of network meta-analysis comparing biologics in the treatment of rheumatoid arthritis. Open
We suggest that the next NMA follows the indications suggested by the Professional Society for Health Economics and Outcomes Research (ISPOR) so that the results are comparable and comprehensible.
View article: It Is the Time to Think About a Treat-to-Target Strategy for Knee Osteoarthritis
It Is the Time to Think About a Treat-to-Target Strategy for Knee Osteoarthritis Open
A Migliore,1 G Gigliucci,1 RJ Petrella,2 RR Bannuru,3 X Chevalier,4 E Maheu,5 R Raman,6 G Herrero-Beaumont,7 N Isailovic,8 M Matucci Cerinc9 1Rheumatology Unit, San Pietro Fatebenefratelli Hospital, Rome, Italy; 2Department of Family Medic…
View article: <p>It Is the Time to Think About a Treat-to-Target Strategy for Knee Osteoarthritis</p>
It Is the Time to Think About a Treat-to-Target Strategy for Knee Osteoarthritis Open
Osteoarthritis (OA) is a rheumatic disease that affects the well-being of the patient, compromises physical and mental function, and affects other quality of life aspects. In the literature, several evidence-based guidelines and recommenda…
View article: High Molecular Weight Hyaluronic Acid (Hyalubrix/HyalOne) for Treating Symptomatic Hip Osteoarthritis
High Molecular Weight Hyaluronic Acid (Hyalubrix/HyalOne) for Treating Symptomatic Hip Osteoarthritis Open
Hip osteoarthritis (OA) causes a set of symptoms that may lead to severe patient impairment, social isolation and morbidity, especially in the elderly.Eventually, patients become candidates for total hip replacement (THR); yet surgery may …
View article: Treat-to-target strategy for knee osteoarthritis. International technical expert panel consensus and good clinical practice statements
Treat-to-target strategy for knee osteoarthritis. International technical expert panel consensus and good clinical practice statements Open
Background: In this work, we aimed to establish a clinical target in the management of knee osteoarthritis (KOA) and to propose good clinical practice (GCP) statements for carrying out a treat-to-target strategy. Methods: A steering commit…
View article: Expression of immunoglobulin-like transcript 4 as an inhibitory receptor in patients with psoriatic arthritis
Expression of immunoglobulin-like transcript 4 as an inhibitory receptor in patients with psoriatic arthritis Open
Objectives To investigate the presence of immunoglobulin-like transcript (ILT)4 and costimulatory proteins (CD40, CD80 and CD86), as well as tumour necrosis factor (TNF)-α production in antigen-presenting cells (APCs) from patients with ps…