Gianluca Paternoster
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Hemodynamic changes in supra-aortic trunks after transcatheter aortic valve implantation at duplex ultrasound examination Open
Aims The hemodynamic consequences of aortic stenosis (AS) on supra-aortic trunks may play a potential role during the diagnosis of concomitant internal carotid artery (ICA) stenosis by dampening blood flow velocity. To investigate the effe…
Gene expression kinetics in Sepsis After Cardiac Surgery (SACS): a multicentric prospective observational study Open
Objectives Surviving Sepsis Campaign (SSC) defined Sepsis as “ life-threatening organ dysfunction caused by a dysregulated host response to infection ”. Sepsis remains one of the leading causes of morbidity and mortality (17-65 %) worldwid…
View article: Urinary Liver-Type Fatty Acid Binding Protein as a Postoperative Marker of Acute Kidney Injury in Patients Undergoing EndovascularAortic Aneurysm Repair
Urinary Liver-Type Fatty Acid Binding Protein as a Postoperative Marker of Acute Kidney Injury in Patients Undergoing EndovascularAortic Aneurysm Repair Open
Urinary L-FABP is emerging as a sensitive biomarker for AKI in patients undergoing EVAR.
Opioid-sparing Anesthesia in Cardiac Surgery: A Meta-analysis Open
This systematic review and meta-analysis evaluated the impact of opioid-sparing versus opioid-based anesthesia in adult patients undergoing cardiac surgery. A comprehensive literature search was conducted across major databases from 2015 t…
View article: Pirfenidone to prevent fibrosis in acute respiratory distress syndrome: The PIONEER study protocol
Pirfenidone to prevent fibrosis in acute respiratory distress syndrome: The PIONEER study protocol Open
This trial was registered on ClinicalTrials.gov with the trial identification NCT05075161.
Phytochemical Composition and Wound Healing Properties of Echinacea angustifolia DC. Root Hydroalcoholic Extract Open
The therapeutic potential of natural products has led to the exploitation of phytocomplexes for treating various skin conditions, including wounds. Echinacea angustifolia DC. has traditionally been used for wound healing, burns, and other …
View article: Perspectives on the Role of Thoracic Fascial Blocks in Cardiac Anaesthesia: Will They Represent a New Era?
Perspectives on the Role of Thoracic Fascial Blocks in Cardiac Anaesthesia: Will They Represent a New Era? Open
Cardiac surgery is continuously evolving, with increasing skills required by the cardiac anaesthesiologist. Following the advent of intraoperative echocardiography, we are witnessing a potential new revolution for the cardiac anaesthesiolo…
View article: 2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery
2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery Open
The current document presents a revision of the 2019 EACTS/EACTA/EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery, emerging from a collaborative effort among the EBCP, EACTAIC and EACTS to establish guidance for unified c…
View article: 2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery
2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery Open
The current document presents a revision of the 2019 EACTS/EACTA/EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery, emerging from a collaborative effort among the EBCP, EACTAIC and EACTS to establish guidance for unified c…
View article: Rising Above the Limits of Critical Care ECMO: A Narrative Review
Rising Above the Limits of Critical Care ECMO: A Narrative Review Open
Extracorporeal membrane oxygenation (ECMO), an advanced life support method, was developed to treat severe cardiac and pulmonary failure in critically ill patients. ECMO was previously used to treat ARDS, cardiogenic shock, and after heart…
View article: Establishing an Extracorporeal Cardiopulmonary Resuscitation Program
Establishing an Extracorporeal Cardiopulmonary Resuscitation Program Open
Extracorporeal cardiopulmonary resuscitation (ECPR) is a complex, life-saving procedure that uses mechanical support for patients with refractory cardiac arrest, representing the pinnacle of extracorporeal membrane oxygenation (ECMO) appli…
View article: Recommendations for fast-track extubation in adult cardiac surgery patients: a consensus statement
Recommendations for fast-track extubation in adult cardiac surgery patients: a consensus statement Open
In the first consensus document ever published by a scientific society addressing practical recommendations for fast-track extubation post-cardiac surgery, the authors identified sixteen interventions commonly associated with fast-track ex…
Extracorporeal membrane oxygenation for prevention of barotrauma in patients with respiratory failure: A scoping review Open
Background Barotrauma is a frequent complication in patients with severe respiratory failure and is associated with poor outcomes. Extracorporeal membrane oxygenation (ECMO) implantation allows to introduce lung‐protective ventilation stra…
View article: The use of angiotensin II for the management of distributive shock: expert consensus statements
The use of angiotensin II for the management of distributive shock: expert consensus statements Open
Background Despite the growing body of evidence supporting the use of angiotensin II (ATII) in distributive shock, its integration into existing treatment algorithms requires careful consideration of factors related to patient comorbiditie…
Hemodynamic Changes in Supra Aortic Trunks after Transcatheter Aortic Valve Implantation at Duplex Ultrasound Examination Open
The hemodynamic consequences of the aortic stenosis (AS) on supraortic trunks may have a po-tential role in the diagnosis of concomitant internal carotid artery (ICA) stenosis by dampening blood flow velocity. To investigate the effect of …
View article: A Randomized Trial of Intravenous Amino Acids for Kidney Protection
A Randomized Trial of Intravenous Amino Acids for Kidney Protection Open
Among adult patients undergoing cardiac surgery, infusion of amino acids reduced the occurrence of AKI. (Funded by the Italian Ministry of Health; PROTECTION ClinicalTrials.gov number, NCT03709264.).
View article: Dexamethasone compared to dexmedetomidine as parasternal block adjunct in cardiac surgery patients: an observational study.
Dexamethasone compared to dexmedetomidine as parasternal block adjunct in cardiac surgery patients: an observational study. Open
Background: Pain after cardiac surgery sternotomy is severe and compromises the respiratory mechanism leading to a delayed extubation. The parasternal block provides a long-lasting pain relief when performed with the use of adjuvants such …
Cryoglobulinemia: the “cold” problem in cardiac surgery, a single-center experience and a literature review Open
Cardiac surgery with cardiopulmonary bypass (CBP) is essential for different cardiac procedures in order to perform surgery with a clear sight field. To safely perform surgery with CPB and preserve brain, kidney, and patient tissue from is…
View article: Argipressin-norepinephrine association in the treatment of septic shock: the use of the polydistrectual resistance index as an assessment of vascular compliance
Argipressin-norepinephrine association in the treatment of septic shock: the use of the polydistrectual resistance index as an assessment of vascular compliance Open
Introduction The hemodynamic management of septic patients involves initial fluid therapy, followed by the use of vasoconstrictors in case of treatment failure. The latest Surviving Sepsis Campaign guidelines suggest the synergistic use of…
View article: Evaluation of Left Ventricular Overload and Use of Unloading Techniques in Venoarterial Extracorporeal Life Support: A Nationwide Survey
Evaluation of Left Ventricular Overload and Use of Unloading Techniques in Venoarterial Extracorporeal Life Support: A Nationwide Survey Open
Cardiogenic shock (CS) and cardiac arrest (CA) are among the most lethal complications of acute cardiovascular disease, affected by high in-hospital mortality rates. Venoarterial extracorporeal life support (VA ECLS) is increasingly used e…