Gianluca Tamaro
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View article: Elevated Alpha-Fetoprotein in Hypothyroidism
Elevated Alpha-Fetoprotein in Hypothyroidism Open
Alpha-fetoprotein (AFP) is a biomarker commonly used in the diagnosis of various malignancies but may also be elevated in non-neoplastic conditions, including hypothyroidism. We report the case of a 3-year-old girl with Down syndrome (DS) …
View article: Differences in growth in prepubertal children with definite growth hormone deficiency, short stature unresponsive to stimulation tests, and idiopathic short stature treated with recombinant human growth hormone: a retrospective study
Differences in growth in prepubertal children with definite growth hormone deficiency, short stature unresponsive to stimulation tests, and idiopathic short stature treated with recombinant human growth hormone: a retrospective study Open
Introduction Growth hormone stimulation tests are crucial in diagnosing growth hormone deficiency (GHD) in children; however, their limited reliability and inconsistent thresholds pose diagnostic challenges. A proposed subclassification di…
View article: Polygenic score from MODY genes is associated with type 1 diabetes and disease characteristics
Polygenic score from MODY genes is associated with type 1 diabetes and disease characteristics Open
View article: Use of gonadotropin-releasing hormone agonists in transgender and gender diverse youth: a systematic review
Use of gonadotropin-releasing hormone agonists in transgender and gender diverse youth: a systematic review Open
Introduction Puberty suppression using gonadotropin-releasing hormone agonists (GnRHa) is a reversible medical intervention that halts endogenous puberty, allowing transgender and gender-diverse (TGD) adolescents to avoid the development o…
View article: Back to normal? A retrospective study on stimulation test and endocrinological diagnosis before, during and after COVID-19 pandemics
Back to normal? A retrospective study on stimulation test and endocrinological diagnosis before, during and after COVID-19 pandemics Open
Introduction The COVID-19 pandemic disrupted healthcare systems, affecting consultations and diagnostics. In pediatric endocrinology, referral patterns shifted, with increased central precocious puberty (CPP) diagnoses and decreased growth…
View article: Long-acting growth hormones: innovations in treatment and guidance on patient selection in pediatric growth hormone deficiency
Long-acting growth hormones: innovations in treatment and guidance on patient selection in pediatric growth hormone deficiency Open
Long-acting growth hormones (LAGHs) represent a significant advancement in the treatment of pediatric GH deficiency, offering an alternative to daily recombinant human GH (rhGH) therapy. Traditional rhGH treatments, although effective, req…
View article: Perceptions and understanding of family pediatricians regarding the new Italian Type 1 Diabetes screening program
Perceptions and understanding of family pediatricians regarding the new Italian Type 1 Diabetes screening program Open
View article: Minimizing unnecessary brain magnetic resonance imaging in pediatric endocrinology: a retrospective cohort analysis
Minimizing unnecessary brain magnetic resonance imaging in pediatric endocrinology: a retrospective cohort analysis Open
Background Brain magnetic resonance imaging (MRI) is mandatory or highly recommended in many pediatric endocrinological conditions to detect causative anatomic anomalies and rule out neoplastic lesions. However, MRI can also show findings …
View article: Clinical and laboratory characteristics but not response to treatment can distinguish children with definite growth hormone deficiency from short stature unresponsive to stimulation tests
Clinical and laboratory characteristics but not response to treatment can distinguish children with definite growth hormone deficiency from short stature unresponsive to stimulation tests Open
Introduction It has been proposed that not all children with short stature displaying an inadequate response to tests for growth hormone (GH) secretion truly suffer from GH deficiency (GHD). Only children with a monogenic cause of GHD or a…
View article: Central Precocious Puberty in Italian Boys: Data From a Large Nationwide Cohort
Central Precocious Puberty in Italian Boys: Data From a Large Nationwide Cohort Open
Context There are only a few nationwide studies on boys with central precocious puberty (CPP) and the last Italian study is a case series of 45 boys that dates back to 2000. Objective We aimed to evaluate the causes of CPP in boys diagnose…
View article: Developing Strategies to Improve Diabetes Management in College-Going Young Adults
Developing Strategies to Improve Diabetes Management in College-Going Young Adults Open
it is a pioneering approach to the world of academia, radically improving the way scholarly research is managed.The grand vision of Frontiers is a world where all people have an equal opportunity to seek, share and generate knowledge.Front…
View article: Short Stature: Beyond Growth Hormone
Short Stature: Beyond Growth Hormone Open
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View article: A Short-Duration Gonadotropin-Releasing Hormone Stimulation Test for the Diagnosis of Central Precocious Puberty
A Short-Duration Gonadotropin-Releasing Hormone Stimulation Test for the Diagnosis of Central Precocious Puberty Open
Background and Objectives: The gonadotropin-releasing hormone (GnRH) stimulation test is the gold standard method for diagnosing central precocious puberty (CPP), although it requires multiple blood samplings over 120 min. This study aimed…
View article: Prevalence and characteristics of thelarche variant
Prevalence and characteristics of thelarche variant Open
Introduction Girls with early thelarche may show an intermediate clinical picture between isolated premature thelarche (PT) and central precocious puberty (CPP), defined as “thelarche variant” (TV), characterized by an FSH-predominant resp…
View article: Screening of lipids and kidney function in children and adolescents with Type 1 Diabetes: does age matter?
Screening of lipids and kidney function in children and adolescents with Type 1 Diabetes: does age matter? Open
Introduction The purpose of this study was to evaluate lipid profile and kidney function in children and adolescents with Type 1 Diabetes. Methods This was a retrospective study including 324 children and adolescents with Type 1 Diabetes (…
View article: Safety of Real-life Usage of Advanced Hybrid Closed-Loop System MiniMed 780G in Children With Type 1 Diabetes Younger Than 7 Years Old
Safety of Real-life Usage of Advanced Hybrid Closed-Loop System MiniMed 780G in Children With Type 1 Diabetes Younger Than 7 Years Old Open
Table 1-Sensor-specific measures of glycemic control, adherence to advanced hybrid closed loop (a-HCL) use, insulin dose and basal-to-bolus ratio
View article: Infant with a big head and ‘crossed’ polysyndactyly
Infant with a big head and ‘crossed’ polysyndactyly Open
A 10-week-old boy was referred to our hospital for polysyndactyly of all four limbs and frontal bossing. He was born at term by emergency caesarean section for pre-eclampsia and breech presentation with Apgar scores of 9 and 10 at 1 and 5 …
View article: Prevalence of children born small for gestational age with short stature who qualify for growth hormone treatment
Prevalence of children born small for gestational age with short stature who qualify for growth hormone treatment Open
View article: ‘Starry sky’ rash in a child
‘Starry sky’ rash in a child Open
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View article: Pattern and Features of Pediatric Endocrinology Referrals: A Retrospective Study in a Single Tertiary Center in Italy
Pattern and Features of Pediatric Endocrinology Referrals: A Retrospective Study in a Single Tertiary Center in Italy Open
Introduction: The knowledge of the pattern and the features of pediatric endocrinology referrals is crucial to optimize resources and guide public health interventions. We explored the numbers and the reasons for referral to a pedia…
View article: A fascinating rheumatologic association
A fascinating rheumatologic association Open
View article: Retrospective study showed that palpitations with tachycardia on admission to a paediatric emergency department were related to cardiac arrhythmias
Retrospective study showed that palpitations with tachycardia on admission to a paediatric emergency department were related to cardiac arrhythmias Open
Aim This retrospective study reviewed the prevalence and long‐term prognosis of children aged 0–18 with palpitations who were admitted to the emergency department (ED) of an Italian paediatric hospital. Methods We examined all admissions t…
View article: A Child with Diminished Linear Growth and Waddling Gait
A Child with Diminished Linear Growth and Waddling Gait Open