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View article: Recommendations for the diagnosis and management of eosinophilic esophagitis in adults and children in Canada: a Delphi consensus project
Recommendations for the diagnosis and management of eosinophilic esophagitis in adults and children in Canada: a Delphi consensus project Open
View article: Recommendations for the diagnosis and management of eosinophilic esophagitis in adults and children in Canada: a Delphi consensus project
Recommendations for the diagnosis and management of eosinophilic esophagitis in adults and children in Canada: a Delphi consensus project Open
Background Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus that effects both pediatrics and adult patients in Canada and is increasing in prevalence. No Canadian focused best practice recommendations curre…
View article: Comorbidities in Canadian patients with hereditary angioedema: a quantitative survey study
Comorbidities in Canadian patients with hereditary angioedema: a quantitative survey study Open
Background Evidence linking hereditary angioedema (HAE) to the potential association of developing other comorbidities, and how it is affected by HAE treatment is needed. The objective of this study is to identify comorbidities and measure…
View article: Angioedema
Angioedema Open
Angioedema can occur in the absence of urticaria and can be broadly divided into three main categories: mast cell-mediated (e.g., histamine), non-mast-cell-mediated (bradykinin-induced) and idiopathic angioedema. Non-mast-cell-mediated ang…
View article: Revaccination outcomes among adolescents and adults with suspected hypersensitivity reactions following COVID-19 vaccination: A Canadian immunization research network study
Revaccination outcomes among adolescents and adults with suspected hypersensitivity reactions following COVID-19 vaccination: A Canadian immunization research network study Open
Most individuals in this national cohort who experienced a hypersensitivity event following COVID-19 vaccination and were referred for specialist review were revaccinated without AEFI recurrence, suggesting that specialist evaluation can f…
View article: A Patient Charter for Chronic Urticaria
A Patient Charter for Chronic Urticaria Open
View article: Case Report: Allergic Rhinitis
Case Report: Allergic Rhinitis Open
Case #1 A 32-year-old female presents to her primary healthcare professional (HCP) with a long history of intermittent nasal congestion, sneezing, rhinorrhea, and itchy eyes. She recalls experiencing these symptoms in high school, but note…
View article: Correction: Transitioning subcutaneous immunoglobulin 20% therapies in patients with primary and secondary immunodeficiencies: Canadian real‑world study
Correction: Transitioning subcutaneous immunoglobulin 20% therapies in patients with primary and secondary immunodeficiencies: Canadian real‑world study Open
View article: A multicenter chart review of patient characteristics, treatment, and outcomes in hereditary angioedema: unmet need for more effective long-term prophylaxis
A multicenter chart review of patient characteristics, treatment, and outcomes in hereditary angioedema: unmet need for more effective long-term prophylaxis Open
View article: Diagnostic complexe : Œdème de Quincke héréditaire apparaissant durant la grossesse
Diagnostic complexe : Œdème de Quincke héréditaire apparaissant durant la grossesse Open
[Voir la version anglaise de l’article ici : www.cmaj.ca/lookup/doi/10.1503/cmaj.220604][1] Points clés Une femme enceinte de 23 ans (2 grossesses, 1 avortement/fausse-couche, 0 parité) ayant des antécédents d’anxiété (traitée par citalopr…
View article: The Evidence and Clinical Rationale for the Use of JAK Inhibitors in the Management of AD
The Evidence and Clinical Rationale for the Use of JAK Inhibitors in the Management of AD Open
Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases affecting 1 in 5 children and 1 in 10–20 adults. AD is characterized by clinical symptoms and signs of erythema, edema, excoriation, lichenification, xeros…
View article: A challenging diagnosis: hereditary angioedema presenting during pregnancy
A challenging diagnosis: hereditary angioedema presenting during pregnancy Open
KEY POINTS A 23-year-old pregnant woman (gravida 2, abortion/miscarriage 1, para 0) with a history of anxiety (treated with citalopram) and cocaine use (stopped before pregnancy) and no family history of swelling presented to hospital at 9…
View article: Transitioning subcutaneous immunoglobulin 20% therapies in patients with primary and secondary immunodeficiencies: Canadian real-world study
Transitioning subcutaneous immunoglobulin 20% therapies in patients with primary and secondary immunodeficiencies: Canadian real-world study Open
Background Real-world data on transitioning to Immune Globulin Subcutaneous (Human) 20% solution (Ig20Gly) are limited. This study aimed to assess infusion parameters and experience of patients with primary (PID) or secondary immunodeficie…
View article: Impact of lanadelumab in hereditary angioedema: a case series of 12 patients in Canada
Impact of lanadelumab in hereditary angioedema: a case series of 12 patients in Canada Open
Background Hereditary angioedema (HAE) is a rare autosomal dominant disease resulting in recurring episodes of swelling, leading to considerable patient morbidity and mortality. Lanadelumab is a plasma kallikrein inhibitor that is approved…
View article: Correction to: The International/Canadian Hereditary Angioedema Guideline
Correction to: The International/Canadian Hereditary Angioedema Guideline Open
View article: The International/Canadian Hereditary Angioedema Guideline
The International/Canadian Hereditary Angioedema Guideline Open
This is an update to the 2014 Canadian Hereditary Angioedema Guideline with an expanded scope to include the management of hereditary angioedema (HAE) patients worldwide. It is a collaboration of Canadian and international HAE experts and …
View article: MOESM2 of The International/Canadian Hereditary Angioedema Guideline
MOESM2 of The International/Canadian Hereditary Angioedema Guideline Open
Additional file 2. HAE Lower Quality Comparison Study Evidence Tables. Lower Quality Comparison Studies. Includes data extraction, quality assessments, and study reference codes and citations for lower quality comparison studies.
View article: MOESM1 of The International/Canadian Hereditary Angioedema Guideline
MOESM1 of The International/Canadian Hereditary Angioedema Guideline Open
Additional file 1. HAE RCT Evidence Tables. Randomized Controlled Trials. Includes data extraction, quality assessments, and study reference codes and citations for randomized controlled trials.
View article: The diagnosis of hereditary angioedema with C1 inhibitor deficiency: a survey of Canadian physicians and laboratories
The diagnosis of hereditary angioedema with C1 inhibitor deficiency: a survey of Canadian physicians and laboratories Open
View article: P008: Hereditary Angioedema Rapid Triage Tool (HAE-RT): translating clinical research into clinical practice
P008: Hereditary Angioedema Rapid Triage Tool (HAE-RT): translating clinical research into clinical practice Open
View article: Patient demographics and real-world use of omalizumab for the treatment of chronic spontaneous/idiopathic urticaria in Canada
Patient demographics and real-world use of omalizumab for the treatment of chronic spontaneous/idiopathic urticaria in Canada Open
View article: Insights and advances in chronic urticaria: a Canadian perspective
Insights and advances in chronic urticaria: a Canadian perspective Open