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View article: A total endoscopic levonorgestrel-releasing intrauterine system (LNG-IUS) placement: a novel approach for obese patients with early-stage endometrial cancer
A total endoscopic levonorgestrel-releasing intrauterine system (LNG-IUS) placement: a novel approach for obese patients with early-stage endometrial cancer Open
This is the first description of a total endoscopic technique for LNG-IUS placement performed without speculum or anesthesia.
View article: SGLT2 inhibitor dapagliflozin mitigates skeletal muscle pathology by modulating key proteins involved in glucose and ion homeostasis in an animal model of heart failure
SGLT2 inhibitor dapagliflozin mitigates skeletal muscle pathology by modulating key proteins involved in glucose and ion homeostasis in an animal model of heart failure Open
Heart failure (HF) is a syndrome characterized by dyspnoea, fatigue and exercise intolerance. Among non-cardiac comorbidities which often accompany HF, skeletal muscle abnormalities impact patients' daily activities and quality of life. So…
View article: Robotic-assisted versus conventional laparoscopic surgery in the management of obese patients with early endometrial cancer in the sentinel lymph node era: a randomized controlled study (RObese)
Robotic-assisted versus conventional laparoscopic surgery in the management of obese patients with early endometrial cancer in the sentinel lymph node era: a randomized controlled study (RObese) Open
View article: Intraluminal tumor cells and prognostic accuracy of endometrial cancer stage criteria: A multi-institution study
Intraluminal tumor cells and prognostic accuracy of endometrial cancer stage criteria: A multi-institution study Open
View article: #226 Exploring the association between different mismatch repair deficient phenotypes and prognostic factors in endometrial cancer: a descriptive analysis
#226 Exploring the association between different mismatch repair deficient phenotypes and prognostic factors in endometrial cancer: a descriptive analysis Open
Introduction/Background Mismatch repair deficiency (MMRd) accounts for 20–30% of all endometrial cancers (EC). MMRd ECs are characterized by the loss of at least one of the MMR proteins (MLH1/PMS2/MSH2/MSH6) at immunohistochemistry (IHC), …
View article: Impact of comorbidities and extent of lymphadenectomy on quality of life in endometrial cancer patients treated with minimally invasive surgery in the era of sentinel lymph nodes
Impact of comorbidities and extent of lymphadenectomy on quality of life in endometrial cancer patients treated with minimally invasive surgery in the era of sentinel lymph nodes Open
View article: Evaluation of the one-step nucleic acid amplification method for rapid detection of lymph node metastases in endometrial cancer: prospective, multicenter, comparative study
Evaluation of the one-step nucleic acid amplification method for rapid detection of lymph node metastases in endometrial cancer: prospective, multicenter, comparative study Open
View article: 2022-RA-585-ESGO Come back to the future: the impact of estrogen receptor profile in the era of molecular endometrial cancer classification
2022-RA-585-ESGO Come back to the future: the impact of estrogen receptor profile in the era of molecular endometrial cancer classification Open
View article: 2022-RA-1346-ESGO Predictive factors for adnexal involvement in Endometrial Cancer, with a focus on FIGO Stage IIIA, an uncommon entity
2022-RA-1346-ESGO Predictive factors for adnexal involvement in Endometrial Cancer, with a focus on FIGO Stage IIIA, an uncommon entity Open
View article: O005/#190 Where there is smoke, there is fire: understanding the implications of positive sentinel lymph nodes in endometrial cancer
O005/#190 Where there is smoke, there is fire: understanding the implications of positive sentinel lymph nodes in endometrial cancer Open
Objectives The objective of this study is to identify clinicopathologic characteristics associated with non-sentinel lymph node (SLN) metastasis and non-vaginal recurrences in patients with SLN-positive endometrial cancer (EC). Methods Con…
View article: 864 Minimally invasive versus open hysterectomy in high-risk endometrial cancer: a propensity score matching analysis
864 Minimally invasive versus open hysterectomy in high-risk endometrial cancer: a propensity score matching analysis Open
Introduction/Background* Randomized trials have shown comparable oncologic outcomes between open versus minimally invasive surgery for endometrial cancer. Limited data is available specifically in patients with high-risk disease. The aim o…
View article: 4K versus 3D total laparoscopic hysterectomy by resident in training: a prospective randomised trial
4K versus 3D total laparoscopic hysterectomy by resident in training: a prospective randomised trial Open
Background: The introduction of ultra-high-definition laparoscopic cameras (4K), by providing stronger monocular depth perception, could challenge the existing 3D technology. There are few available studies on this topic, especially in gyn…
View article: In search for biomarkers and potential drug targets for uterine serous endometrial cancer
In search for biomarkers and potential drug targets for uterine serous endometrial cancer Open
Objective Serous endometrial cancer (USC) is a challenging malignancy associated with metastasis, recurrence and poor outcome. To identify clinically relevant prognostic biomarkers, we focused on a panel of proteins selected after a compre…
View article: Adjuvant chemotherapy in early-stage endometrioid endometrial cancer with >50% myometrial invasion and negative lymph nodes
Adjuvant chemotherapy in early-stage endometrioid endometrial cancer with >50% myometrial invasion and negative lymph nodes Open
View article: 11 Oncologic outcomes and role of adjuvant therapy in endometrial cancer patients with low volume metastasis in the sentinel lymph nodes: an international multi-institutional study
11 Oncologic outcomes and role of adjuvant therapy in endometrial cancer patients with low volume metastasis in the sentinel lymph nodes: an international multi-institutional study Open
Objective To assess recurrence-free survival (RFS) and role of adjuvant therapy (ATx) in endometrial cancer with low volume metastasis (LVM) in sentinel lymph nodes (SLN). Methods Patients with SLN LVM (≤2 mm) during 2010–2018 were retrosp…
View article: 25 Endometrial cancer: laparoscopy vs robotic surgery. A large single-institution retrospective analysis
25 Endometrial cancer: laparoscopy vs robotic surgery. A large single-institution retrospective analysis Open
Introduction Minimally invasive surgery (MIS) is the gold standard for endometrial cancer staging. Among MIS approaches, laparoscopy (LPS) and robotic surgery (RS) are the major techniques. The aim of this study is to compare these two app…
View article: 37 Quantitative evaluation of lymph-vascular space invasion (LVSI) in patients affected by endometrial cancer: prognostic and clinical implications
37 Quantitative evaluation of lymph-vascular space invasion (LVSI) in patients affected by endometrial cancer: prognostic and clinical implications Open
Objectives Lymph-vascular space invasion (LVSI) is associated with an increased risk of recurrence. Usually, the interpretation of LVSI is just qualitative, as presence or absence. The aim of this study is to examine the quantitative analy…
View article: 224 Adjuvant chemotherapy in surgical stage I or II endometrioid endometrial cancer with myometrial invasion >50%: a multicenter retrospective study with long-term follow-up
224 Adjuvant chemotherapy in surgical stage I or II endometrioid endometrial cancer with myometrial invasion >50%: a multicenter retrospective study with long-term follow-up Open
FIGURE 7. Head ventral view of the hypertrophied odontodes in adult males of: A) N. paranensis, DZSJRP 7003, 81.3 mm SL; B) N. yapo, DZSJRP 6194, 105.2 mm SL and; C) N. selenae, DZSJRP 7449, 95.8 mm SL.
View article: A case of multi-agent drug resistant choriocarcinoma treated with Pembrolizumab
A case of multi-agent drug resistant choriocarcinoma treated with Pembrolizumab Open
•High-risk multi-agent drug resistant GTN is a life threatening disease.•Majority of choriocarcinomas show intense PD-L1 immunoreactivity.•Pembrolizumab increases antitumor activity.•Effectiveness of Pembrolizumab in treating patients with…