Giorgia Spinazzola
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View article: Pediatric acute respiratory distress syndrome in children with type I - spinal muscular atrophy: a 12-year case series
Pediatric acute respiratory distress syndrome in children with type I - spinal muscular atrophy: a 12-year case series Open
Spinal muscular atrophy type 1 (SMA-1), a disease affecting the lower motor neurons in the anterior horn cells, causes substantial respiratory morbidity and mortality in children. While recent advances in disease modifying treatments (DMTs…
View article: Early Detection of Palliative Care Needs in Critically Ill Patients Using the NECPAL Tool
Early Detection of Palliative Care Needs in Critically Ill Patients Using the NECPAL Tool Open
Background: Palliative care is essential in intensive care, improving symptom control, quality of life, and reducing hospital stays without increasing mortality. However, early identification of patients who could benefit remains a major c…
View article: New Trends in Airway Management During Endoscopic Retrograde Cholangiopancreatography: A Narrative Review
New Trends in Airway Management During Endoscopic Retrograde Cholangiopancreatography: A Narrative Review Open
Over time, endoscopic retrograde cholangiopancreatography (ERCP) evolved into the preferred method for both diagnosing and treating diseases of the biliary, pancreatic, and ampullary systems. Traditionally performed under “conscious” sedat…
View article: Discrepancy Between Conventional Coagulation Tests and Thromboelastography During the Early Postoperative Phase of Liver Resection in Neoplastic Patients: A Prospective Study Using the New-Generation TEG®6s
Discrepancy Between Conventional Coagulation Tests and Thromboelastography During the Early Postoperative Phase of Liver Resection in Neoplastic Patients: A Prospective Study Using the New-Generation TEG®6s Open
Background: Thromboelastography-6s (TEG®6s), a novel device developed to assess coagulation status, presents advantages such as less frequent calibration, ease of use, and greater stability against movements compared to the previous system…
View article: “Evaluation of Different Inspiratory Efforts in a Pediatric Model of Healthy Lung and Pediatric Acute Respiratory Distress Syndrome During Optimized Pressure Support Ventilation and Proportional Assist Ventilation Plus (PAV+): A Bench Study
“Evaluation of Different Inspiratory Efforts in a Pediatric Model of Healthy Lung and Pediatric Acute Respiratory Distress Syndrome During Optimized Pressure Support Ventilation and Proportional Assist Ventilation Plus (PAV+): A Bench Study Open
Introduction While proportional ventilator modes have gained popularity in adult patients’ ventilatory management, Proportional Assist Ventilation (PAV+) use in pediatric patients with Pediatric Acute Respiratory Distress Syndrome (PARDS) …
View article: Effect of neurally adjusted ventilator assist versus pressure support ventilation on asynchronies and cardiac function in pediatric liver transplantation
Effect of neurally adjusted ventilator assist versus pressure support ventilation on asynchronies and cardiac function in pediatric liver transplantation Open
In pediatric liver recipients perioperative factors may affect respiratory and cardiac function, and prolong mechanical ventilation during post-operative period. The use of NAVA can improve the interaction between the patient and the venti…
View article: Reply to Riva et al. Comment on “Gaspari et al. Blood Purification in Hepatic Dysfunction after Liver Transplant or Extensive Hepatectomy: Far from the Best-Case Scenarios. J. Clin. Med. 2024, 13, 2853”
Reply to Riva et al. Comment on “Gaspari et al. Blood Purification in Hepatic Dysfunction after Liver Transplant or Extensive Hepatectomy: Far from the Best-Case Scenarios. J. Clin. Med. 2024, 13, 2853” Open
We sincerely appreciate the authors’ comments [...]
View article: Deep sedation in lateral position for preterm infants during cerebral magnetic resonance imaging: a pilot study
Deep sedation in lateral position for preterm infants during cerebral magnetic resonance imaging: a pilot study Open
Introduction Respiratory adverse events are common during the sedation of preterm babies, often needing active airway support. During magnetic resonance imaging, this occurrence could extend the acquisition time, with a negative impact on …
View article: Management of analgosedation during noninvasive respiratory support: an expert Delphi consensus document developed by the Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care (SIAARTI)
Management of analgosedation during noninvasive respiratory support: an expert Delphi consensus document developed by the Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care (SIAARTI) Open
View article: Focus on the Role of Non-Invasive Respiratory Support (NRS) during Palliative Care in Patients with Life-Limiting Respiratory Disease
Focus on the Role of Non-Invasive Respiratory Support (NRS) during Palliative Care in Patients with Life-Limiting Respiratory Disease Open
The management of patients with life-threatening respiratory disease in the ICU and at home has become increasingly of interest over the past decades. Growing knowledge supports the use of NRS, aimed at improving patient comfort and improv…
View article: Blood Purification in Hepatic Dysfunction after Liver Transplant or Extensive Hepatectomy: Far from the Best-Case Scenarios
Blood Purification in Hepatic Dysfunction after Liver Transplant or Extensive Hepatectomy: Far from the Best-Case Scenarios Open
Background: Hepatic dysfunction (HD) after liver transplantation (LT) or extended hepatic resection (EHR) is associated with graft failure and high short-term mortality. We evaluated the safety and depurative efficacy of CytoSorb® in these…
View article: Deep Sedation in Lateral Position for Preterm Infants during Cerebral Magnetic Resonance Imaging: a Prospective Observational Study
Deep Sedation in Lateral Position for Preterm Infants during Cerebral Magnetic Resonance Imaging: a Prospective Observational Study Open
Purpose: Respiratory adverse events are common during sedation of preterm babies, often needing an active airways support. During magnetic resonance imaging it could extend the acquisition time, with negative impact on the thermic and meta…
View article: High vs Low PEEP in Patients With ARDS Exhibiting Intense Inspiratory Effort During Assisted Ventilation
High vs Low PEEP in Patients With ARDS Exhibiting Intense Inspiratory Effort During Assisted Ventilation Open
View article: Prone Positioning and Molecular Biomarkers in COVID and Non-COVID ARDS: A Narrative Review
Prone Positioning and Molecular Biomarkers in COVID and Non-COVID ARDS: A Narrative Review Open
Prone positioning (PP) represents a therapeutic intervention with the proven capacity of ameliorating gas exchanges and ventilatory mechanics indicated in acute respiratory distress syndrome (ARDS). When PP is selectively applied to modera…
View article: Intensive Care Unit-Acquired Weakness after Liver Transplantation: Analysis of Seven Cases and a Literature Review
Intensive Care Unit-Acquired Weakness after Liver Transplantation: Analysis of Seven Cases and a Literature Review Open
Intensive Care Unit (ICU)-Acquired Weakness (ICU-AW) is a generalized muscle weakness that is clinically detected in critical patients and has no plausible etiology other than critical illness. ICU-AW is uncommon in patients undergoing ort…
View article: Comparative evaluation of three total full-face masks for delivering Non-Invasive Positive Pressure Ventilation (NPPV): a bench study
Comparative evaluation of three total full-face masks for delivering Non-Invasive Positive Pressure Ventilation (NPPV): a bench study Open
Historically, the oro-nasal mask has been the preferred interface to deliver Non-Invasive Positive Pressure Ventilation (NPPV) in critically ill patients. To overcome the problems related to air leaks and discomfort, Total Full-face masks …
View article: Influence of total face masks design and circuit on synchrony and performance during pressure support ventilation: A bench study
Influence of total face masks design and circuit on synchrony and performance during pressure support ventilation: A bench study Open
The MTFM showed a significantly better patient ventilator interaction and a better ventilator performance, suggesting that this kind of total face mask design should be preferred in clinical practice.
View article: Children and neonates anesthesia in magnetic resonance environment in Italy: an active call survey
Children and neonates anesthesia in magnetic resonance environment in Italy: an active call survey Open
View article: Children and Neonates Anesthesia in Magnetic Resonance Environment in Italy. An active Call Survey
Children and Neonates Anesthesia in Magnetic Resonance Environment in Italy. An active Call Survey Open
Background Pediatric anesthesia care in the Magnetic Resonance Imaging is a challenge for clinicians. The recent debate about the role of anesthetic agent on neural development, encouraged an evaluation of their actual activity in this env…
View article: Pain Management Optimisation by an Ultrasound-Guided Analgesic Technique in Outpatients with Plantar Fasciitis during High-Energy Extracorporeal Shock Wave Therapy
Pain Management Optimisation by an Ultrasound-Guided Analgesic Technique in Outpatients with Plantar Fasciitis during High-Energy Extracorporeal Shock Wave Therapy Open
US-guided PTNB resulted a valid support for the HEWST in outpatients with plantar fasciitis because it reduced the pain during the procedure, allowing to minimise the patient discomfort and to give the therapeutic doses just in three sessi…
View article: Protective effect of SARS‐CoV‐2 preventive measures against ESKAPE and <i>Escherichia coli</i> infections
Protective effect of SARS‐CoV‐2 preventive measures against ESKAPE and <i>Escherichia coli</i> infections Open
Background/Objectives We investigated whether behavioral precautions adopted during Coronavirus disease (COVID‐19) pandemic also influenced the spreading and multidrug resistance (MDR) of ESKAPEEc ( Enterococcus faecium , Staphylococcus au…
View article: Comparative bench study evaluation of a modified snorkeling mask used during COVID-19 pandemic and standard interfaces for non-invasive ventilation
Comparative bench study evaluation of a modified snorkeling mask used during COVID-19 pandemic and standard interfaces for non-invasive ventilation Open
The modified snorkeling mask can be used as an acceptable alternative to other interfaces for both nCPAP and NIV in emergencies.
View article: Comparative bench study evaluation of a modified snorkeling mask used during COVID-19 pandemia and standard interfaces for Non-Invasive Ventilation
Comparative bench study evaluation of a modified snorkeling mask used during COVID-19 pandemia and standard interfaces for Non-Invasive Ventilation Open
Background COVID-19 infection has put enormous pressure on the healthcare systems worldwide and especially on Intensive Care Units (ICUs). In this particular situation, a modified snorkeling mask into a mask for non-invasive continuous pos…
View article: Comparative Bench Study Evaluation of a Modified Snorkeling Mask Used During COVID-19 Pandemia and Standard Interfaces for Non-invasive Ventilation.
Comparative Bench Study Evaluation of a Modified Snorkeling Mask Used During COVID-19 Pandemia and Standard Interfaces for Non-invasive Ventilation. Open
BackgroundCOVID-19 infection has put enormous pressure on the healthcare systems worldwide and especially on Intensive Care Units (ICUs). In this particular situation, a modified snorkeling mask into a mask for non-invasive continuous posi…
View article: Comparative Bench Study Evaluation of a Modified Snorkeling Mask Used During COVID-19 Pandemia and Standard Interfaces for Non-Invasive Ventilation.
Comparative Bench Study Evaluation of a Modified Snorkeling Mask Used During COVID-19 Pandemia and Standard Interfaces for Non-Invasive Ventilation. Open
BackgroundCOVID-19 infection has put enormous pressure on the healthcare systems worldwide and especially on Intensive Care Units (ICUs). In this particular situation, a modified snorkeling mask into a mask for non-invasive continuous posi…
View article: (1,3)-β-d-Glucan-based empirical antifungal interruption in suspected invasive candidiasis: a randomized trial
(1,3)-β-d-Glucan-based empirical antifungal interruption in suspected invasive candidiasis: a randomized trial Open
View article: Pressure Support Ventilation (PSV) versus Neurally Adjusted Ventilatory Assist (NAVA) in difficult to wean pediatric ARDS patients: a physiologic crossover study
Pressure Support Ventilation (PSV) versus Neurally Adjusted Ventilatory Assist (NAVA) in difficult to wean pediatric ARDS patients: a physiologic crossover study Open
View article: Comparative Evaluation of Two Different Post-Operative Analgesia after Hallux Valgus Correction in Day Surgery Patients
Comparative Evaluation of Two Different Post-Operative Analgesia after Hallux Valgus Correction in Day Surgery Patients Open
PTNB group showed a significant reduction of VAS score from the sixth hour after surgery compared to LIA group (p<0.028 at T2, p<0.05 at T3 and p<0.002 at T4, respectively). Instead, no significant differences were found in terms of post-o…
View article: High-Flow Nasal Cannula Versus Standard Oxygen Therapy After Extubation in Liver Transplantation: A Matched Controlled Study
High-Flow Nasal Cannula Versus Standard Oxygen Therapy After Extubation in Liver Transplantation: A Matched Controlled Study Open
Early application of HFNC in the subjects with liver transplantation did not reduce the incidence of hypoxemia after extubation compared with standard O2 and did not modify the incidence of weaning failure, ICU length of stay, a…
View article: Postoperative respiratory failure in liver transplantation: Risk factors and effect on prognosis
Postoperative respiratory failure in liver transplantation: Risk factors and effect on prognosis Open
In conclusion, MELD, restrictive lung pattern, surgical complexity as captured by VVBP, pre-extubation PaCO2 and MEAF are the main predictors of PRF in non-acute LTx patients.