Explanipedia

A rapid assessment of pragmatic abilities and cognitive substrates: The German APACS Brief Open

Ludwig Wilkens, Laura Anna Ciaccio, Thomas Picht, Marta Bosia, Giorgio Arcara , et al. · 2025

BackgroundClinical evaluation of language abilities is central to diagnosing impairments in neurological and neuropsychiatric conditions, such as brain injuries, Parkinson’s disease, or schizophrenia. However, assessment tools predominantl…

When Do Pragmatic Abilities Peak? Assessment of Pragmatic Abilities and Cognitive Substrates–French Version Psychometric Properties Across the Lifespan Open

Nicolas Petit, Flavia Mengarelli, Marie‐Maude Geoffray, Giorgio Arcara, Valentina Bambini · 2025

Purpose: This study aims (a) to assess the psychometric properties of a French adaptation of the Assessment of Pragmatic Abilities and Cognitive Substrates (APACS-Fr), a comprehensive test of pragmatic abilities for French-speaking adolesc…

Resting-state brain dynamics: insights from oscillatory activity in brain networks Open

Jessica Samogin, Sara Zago, Alessandro Tonin, Maura Seynaeve, Toon de Beukelaar , et al. · 2025

Our understanding of brain function has shifted from a focus on localized processing to an emphasis on dynamic interactions among distributed neuronal assemblies connected through structural networks. The resting state provides an ideal co…

Parkinson’s Disease Through the Lens of Metabolomics: A Targeted Systematic Review on Human Studies (2019–2024) Open

F Cannas, Karolina Krystyna Kopeć, Natalia Zuddas, Flaminia Cesare Marincola, Giorgio Arcara , et al. · 2025

Background: Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disorder characterized by motor and non-motor symptoms. As conventional diagnostic methods are limited in their ability to detect early-stage PD or monitor it…

Healthcare Costs by Comorbidity Patterns in Lung Cancer Patients Open

Alessandra Buja, Massimo Rugge, Marcello Di Pumpo, Manuel Zorzi, Federico Rea , et al. · 2025

Introduction: Lung cancer imposes a substantial economic burden on patients, healthcare systems, and societies due to its high prevalence and costs associated with diagnosis, treatment, and palliative care. Comorbidities in lung cancer pat…

Ten years of using the APACS test: a multistudy cross-diagnostic analysis of pragmatic profiles and their relationship with Theory of Mind Open

Federico Frau, Marta Bosia, Luca Bischetti, Gloria Cappelli, Antonio Carotenuto , et al. · 2025

Pragmatic impairments are largely documented, yet rarely considered in clinical practice, also due to a poor characterization of pragmatic profiles across conditions, as well as some overlap with theory of mind (ToM) in the conceptualizati…

Heart Rate Variability and Autonomic Dysfunction After Stroke: Prognostic Markers for Recovery Open

Sara Lago, Toon T. de Beukelaar, Ilaria Casetta, Giorgio Arcara, Dante Mantini · 2025

Stroke is a major cause of long-term disability and mortality worldwide, often resulting in impairments not only in motor and cognitive functions but also in autonomic nervous system (ANS) regulation. Among the physiological markers that r…

Education Shapes the Link Between EEG Aperiodic Components and Cognitive Aging Open

Sara Lago, Sara Zago, Sonia Montemurro, Rocco Salvatore Calabrò, Maria Grazia Maggio , et al. · 2025

Healthy aging brings widespread shifts in aperiodic (non-oscillatory) electroencephalographic (EEG) components, which may underlie physiological changes in cognitive performance. Education, a known protective factor against age-related dec…

Unveiling the neural correlates of prospective memory: An ecological EEG study Open

Paola Santacesaria, Stefano Vicentin, Sara Zago, Giorgio Arcara, Giorgia Cona · 2025

The ability to remember intentions for future actions is a fundamental aspect of human functioning in everyday life. This process is typically studied in laboratory settings with tasks designed to isolate it, but these often lack ecologica…

Risk factors for 30-day unplanned readmissions after surgical procedures in the elderly population Open

Gino Sartor, Marco Fusco, Marzio Milana, Leonardo Rigon, Giorgio Arcara , et al. · 2025

The study highlights the importance of identifying risk factors for readmission to improve transitions of care. Targeted interventions for high-risk populations, particularly those with dementia, renal disease, or cancer, are essential to …

State-dependent associative plasticity highlights function-specific premotor-motor pathways crucial for arbitrary visuomotor mapping Open

Sonia Turrini, Francesca Fiori, Giorgio Arcara, Vincenzo Romei, Giuseppe di Pellegrino , et al. · 2025

Arbitrary visuomotor mapping (AVMM) showcases the brain’s ability to link sensory inputs with actions. The ventral premotor cortex (PMv) is proposed as central to sensorimotor transformations, relaying descending motor commands through the…

Patterns of Comorbidities in Lung Cancer Patients and Survival Open

Alessandra Buja, Marcello Di Pumpo, Massimo Rugge, Manuel Zorzi, Federico Rea , et al. · 2025

Introduction: Comorbidities affect diagnosis and treatments in cancer patients. This study explores the prevalence and patterns of comorbidities in non-small cell lung cancer (NSCLC) patients and their association with survival. Materials …

Ct-Perfusion Absolute Ghost Infarct Core Is a Rare Phenomenon Associated with Poor Collateral Status in Acute Ischemic Stroke Patients Open

Giorgio Busto, Andrea Morotti, Ilaria Casetta, Anna Poggesi, Davide Gadda , et al. · 2025

Background: CT perfusion (CTP) overestimation of core volume >10 mL compared to the final infarct volume (FIV) size is the current definition of the ghost infarct core (GIC) phenomenon. However, subsequent infarct growth might influence FI…

Ten years of using the APACS test: a multistudy cross-diagnostic analysis of pragmatic profiles and their relationship with Theory of Mind Open

Federico Frau, Marta Bosia, Luca Bischetti, Gloria Cappelli, Antonio Carotenuto , et al. · 2025

Pragmatic impairments are largely documented, yet rarely considered in clinical practice, also due to a poor characterization of pragmatic profiles across conditions, as well as some overlap with theory of mind (ToM) in the conceptualizati…

Disentangling clinical heterogeneity in schizophrenia through neuropsychophysiological profiles Open

Giulia Agostoni, Sara Zago, Margherita Bechi, Jacopo Sapienza, Roberto Cavallaro , et al. · 2025

Introduction Cognitive disruption is a key feature in schizophrenia, and the identification of the neurophysiological underpinnings is of particular interest. One of the most promising markers of cognition is aperiodic activity, which is c…

Neural correlates of frailty in cognitively healthy adults: A multimodal imaging study Open

Ilaria Parrotta, Lorenza Maistrello, Giorgio Arcara, Dante Mantini, Giovanni Lazzaro , et al. · 2025

Objective Frailty has emerged as prevalent condition in ageing. While frailty has been assessed through physical and functional criteria, recent studies have explored the link between cognitive decline and frailty, which remains complex an…

Correction to: Improving equivalent scores for clinical neuropsychology: a new method for regression model selection Open

Giorgio Arcara · 2025

Prestimulus functional connectivity reflects attention orientation in a prospective memory task: A magnetoencephalographic (MEG) study Open

Stefano Vicentin, Giorgia Cona, Marco Marino, Patrizia Bisiacchi, Dante Mantini , et al. · 2025

Prospective Memory (PM) is the ability to encode an intention in memory and retrieve it at the right time in the future. After the intention is formed, it must be maintained in memory while simultaneously monitoring the environment until t…

Development and Validation of a Rapid Tool to Measure Pragmatic Abilities: The Brief Assessment of Pragmatic Abilities and Cognitive Substrates (APACS Brief) Open

Luca Bischetti, Federico Frau, Veronica Pucci, Giulia Agostoni, Chiara Pompei , et al. · 2025

Pragmatics is key to communicating effectively, and its assessment in vulnerable populations is of paramount importance. Although tools exist for this purpose, they are often effortful and time-consuming, with complex scoring procedures, w…

When do pragmatic abilities peak? APACS-Fr psychometric properties across the life-span Open

Nicolas Petit, Flavia Mengarelli, Marie-Maude Geoffray Cassar, Giorgio Arcara, Valentina Bambini · 2025

Purpose: This study aims 1) to assess the psychometric properties of the APACS-Fr, a comprehensive test of pragmatic abilities for French speaking adolescents and adults, and 2) to use it to study lifespan variations in pragmatic abilities…

Brain state-dependent plasticity induction through cortico-cortical paired associative stimulation: the role of timing and circuit engagement in the human PMv-to-M1 pathway Open

Sonia Turrini, Andrea Amadori, Sara Zago, Giorgio Arcara, Alessio Avenanti · 2025

Decoding the Neural Dynamics of Everyday Prospective Remembering: A Hidden Markov Model Approach Open

Stefano Vicentin, Davide Buzzi Reschini, Paola Santacesaria, Lisa Toffoli, Sara Zago , et al. · 2025

Selective tACS modulation of aperiodic EEG components: unveiling alternative mechanisms of neural modulation Open

Fabio Masina, Ettore Napoli, Paola Santacesaria, Andreina Giustiniani, Giorgia Cona , et al. · 2025

Validating MEG estimated resting-state connectome with intracranial EEG Open

Jawata Afnan, Zhengchen Cai, Jean‐Marc Lina, Chifaou Abdallah, Giovanni Pellegrino , et al. · 2025

Magnetoencephalography (MEG) is widely used for studying resting-state brain connectivity. However, MEG source imaging is ill posed and has limited spatial resolution. This introduces source-leakage issues, making it challenging to interpr…

Auto-Global Examination of Mental State (Auto-GEMS): a web-based self-administered cognitive screening Open

Veronica Pucci, Giulio Contemori, Maria Silvia Saccani, Giorgio Arcara, Sara Mondini , et al. · 2024

Temporal dynamics of implicit moral evaluation: From empathy for pain to mentalizing processes Open

Kamela Cenka, Chiara Spaccasassi, Stella Petkovic, Rachele Pezzetta, Giorgio Arcara , et al. · 2024

Ten years of using the APACS test: a multistudy cross-diagnostic analysis of pragmatic profiles and their relationship with Theory of Mind Open

Federico Frau, Marta Bosia, Luca Bischetti, Gloria Cappelli, Antonio Carotenuto , et al. · 2024

Pragmatic impairments are largely documented, yet rarely considered in clinical practice, also due to a poor characterization of pragmatic profiles across conditions, as well as some overlap with theory of mind (ToM) in the conceptualizati…

Pre-Stimulus Activity of Left and Right TPJ in Linguistic Predictive Processing: A MEG Study Open

Sara Lago, Sara Zago, Valentina Bambini, Giorgio Arcara · 2024

Background. The left and right temporoparietal junctions (TPJs) are two brain areas involved in several brain networks, largely studied for their diverse roles, from attentional orientation to theory of mind and, recently, predictive proce…

Artificial embodiment displaces cortical neuromagnetic somatosensory responses Open

Silvia L. Isabella, Marco D’Alonzo, Alessandro Mioli, Giorgio Arcara, Giovanni Pellegrino , et al. · 2024

Cognitive reserve in the recovery and rehabilitation of stroke and traumatic brain injury: A systematic review Open

Giulia Oliva, Fabio Masina, Nazanin Hosseinkhani, Sonia Montemurro, Giorgio Arcara · 2024

Objective: Cognitive reserve (CR) is the brain's ability to cope with changes related to aging and/or disease. Originally introduced to explain individual differences in the clinical manifestations of dementia, CR has recently emerg…

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