Giorgio Bonmassar
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View article: A Novel Lead Construct to Reduce MRI-Induced RF Heating: Construction, In Vitro Validation, and In Vivo Predictions
A Novel Lead Construct to Reduce MRI-Induced RF Heating: Construction, In Vitro Validation, and In Vivo Predictions Open
View article: Development and Validation of a High-Resolution Pediatric Computational Model with Application to Transcranial Magnetic Stimulation Coil Evaluation
Development and Validation of a High-Resolution Pediatric Computational Model with Application to Transcranial Magnetic Stimulation Coil Evaluation Open
View article: High-quality multimodal MRI with simultaneous EEG using conductive ink and polymer-thick film nets
High-quality multimodal MRI with simultaneous EEG using conductive ink and polymer-thick film nets Open
Objective . Combining magnetic resonance imaging (MRI) and electroencephalography (EEG) provides a powerful tool for investigating brain function at varying spatial and temporal scales. Simultaneous acquisition of both modalities can provi…
View article: A Polymer Thick Film on an Organic Substrate Grid Electrode and an Open-Source Recording System for UHF MRI: An Imaging Study
A Polymer Thick Film on an Organic Substrate Grid Electrode and an Open-Source Recording System for UHF MRI: An Imaging Study Open
Electrocorticography (ECoG) is a critical tool in preclinical neuroscience research for studying global network activity. However, integrating ECoG with functional magnetic resonance imaging (fMRI) has posed challenges, due to metal electr…
View article: Meet Athena: A Realistic Computer Model of a Child
Meet Athena: A Realistic Computer Model of a Child Open
Have you ever wondered how doctors and scientists test new medical devices or study how the body works? They often use computer models, which are like digital dolls that simulate the human body. But did you know that there are only few com…
View article: Modifying the trajectory of epicardial leads can substantially reduce <scp>MRI</scp> ‐induced <scp>RF</scp> heating in pediatric patients with a cardiac implantable electronic device at 1.5T
Modifying the trajectory of epicardial leads can substantially reduce <span>MRI</span> ‐induced <span>RF</span> heating in pediatric patients with a cardiac implantable electronic device at 1.5T Open
Purpose After epicardial cardiac implantable electronic devices are implanted in pediatric patients, they become ineligible to receive MRI exams due to an elevated risk of RF heating. We investigated whether simple modifications in the tra…
View article: Multi-Segment Leads To Reduce RF Heating in MRI: A Computational Evaluation at 1.5T and 3T
Multi-Segment Leads To Reduce RF Heating in MRI: A Computational Evaluation at 1.5T and 3T Open
Implanted neurostimulators are currently in widespread use and allow patients to receive therapeutic nerve stimulation for a variety of conditions. Such devices often make use of long leads extending from the device to the relevant nerve t…
View article: RF-induced heating of capped and uncapped abandoned epicardial leads during MRI at 1.5 T and 3 T
RF-induced heating of capped and uncapped abandoned epicardial leads during MRI at 1.5 T and 3 T Open
There is a paucity of data regarding the safety of magnetic resonance imaging (MRI) in patients with abandoned epicardial leads. Few studies have reported temperature rises up to 76 °C during MRI at 1.5 T in gel phantoms implanted with epi…
View article: Aluminum Thin Film Nanostructure Traces in Pediatric EEG Net for MRI and CT Artifact Reduction
Aluminum Thin Film Nanostructure Traces in Pediatric EEG Net for MRI and CT Artifact Reduction Open
Magnetic resonance imaging (MRI) and continuous electroencephalogram (EEG) monitoring are essential in the clinical management of neonatal seizures. EEG electrodes, however, can significantly degrade the image quality of both MRI and CT du…
View article: The MotoNet: A 3 Tesla MRI-Conditional EEG Net with Embedded Motion Sensors
The MotoNet: A 3 Tesla MRI-Conditional EEG Net with Embedded Motion Sensors Open
We introduce a new electroencephalogram (EEG) net, which will allow clinicians to monitor EEG while tracking head motion. Motion during MRI limits patient scans, especially of children with epilepsy. EEG is also severely affected by motion…
View article: Numerical Evaluation of Miniaturized Coils for Focal Magnetic Stimulation
Numerical Evaluation of Miniaturized Coils for Focal Magnetic Stimulation Open
View article: A study of flex miniaturized coils for focal nerve magnetic stimulation
A study of flex miniaturized coils for focal nerve magnetic stimulation Open
Background Peripheral magnetic stimulation (PMS) is emerging as a complement to standard electrical stimulation (ES) of the peripheral nervous system (PNS). PMS may stimulate sensory and motor nerve fibers without the discomfort associated…
View article: A high-resolution pediatric female whole-body numerical model with comparison to a male model
A high-resolution pediatric female whole-body numerical model with comparison to a male model Open
Objective . Numerical models are central in designing and testing novel medical devices and in studying how different anatomical changes may affect physiology. Despite the numerous adult models available, there are only a few whole-body pe…
View article: Age and lead configuration matter: A comparative study of RF-induced heating of epicardial and endocardial electronic devices in adult and pediatric anthropomorphic phantoms in 1.5 T MR
Age and lead configuration matter: A comparative study of RF-induced heating of epicardial and endocardial electronic devices in adult and pediatric anthropomorphic phantoms in 1.5 T MR Open
Background Children with congenital heart defects often have life-sustaining indications for a cardiac implantable electronic device (CIED). In children, these devices are typically sewn to the heart epicardium, but the FDA has never licen…
View article: Short-pulsed micro-magnetic stimulation of the vagus nerve
Short-pulsed micro-magnetic stimulation of the vagus nerve Open
Vagus nerve stimulation (VNS) is commonly used to treat drug-resistant epilepsy and depression. The therapeutic effect of VNS depends on stimulating the afferent vagal fibers. However, the vagus is a mixed nerve containing afferent and eff…
View article: A temporal sequence of thalamic activity unfolds at transitions in behavioral arousal state
A temporal sequence of thalamic activity unfolds at transitions in behavioral arousal state Open
View article: A New Phased-Array Magnetic Resonance Imaging Receive-Only Coil for HBO2 Studies
A New Phased-Array Magnetic Resonance Imaging Receive-Only Coil for HBO2 Studies Open
The paper describes a new magnetic resonance imaging (MRI) phased-array receive-only (Rx) coil for studying decompression sickness and disorders of hyperbaricity, including nitrogen narcosis. Functional magnetic resonance imaging (fMRI) is…
View article: Modifying the trajectory of epicardial leads can substantially reduce MRI-induced RF heating in pediatric patients with a cardiac implantable electronic device
Modifying the trajectory of epicardial leads can substantially reduce MRI-induced RF heating in pediatric patients with a cardiac implantable electronic device Open
Purpose Infants and children with congenital heart defects, inherited arrhythmia syndromes, and congenital cardiac conduction disorders often receive epicardial implantable electronic devices. Unfortunately, once an epicardial device is im…
View article: The Position and Orientation of the Pulse Generator Affects MRI RF Heating of Epicardial Leads in Children
The Position and Orientation of the Pulse Generator Affects MRI RF Heating of Epicardial Leads in Children Open
Infants and children with congenital heart defects often receive a cardiac implantable electronic device (CIED). Because transvenous access to the heart is difficult in patients with small veins, the majority of young children receive epic…
View article: A comparative study of MRI-induced RF heating in pediatric and adult populations with epicardial and endocardial implantable electronic devices
A comparative study of MRI-induced RF heating in pediatric and adult populations with epicardial and endocardial implantable electronic devices Open
Patients with congenital heart defects, inherited arrhythmia syndromes, and congenital disorders of cardiac conduction often receive a cardiac implantable electronic device (CIED). At least 75% of patients with CIEDs will need magnetic res…
View article: A temporal sequence of thalamic activity unfolds at transitions in behavioral arousal state
A temporal sequence of thalamic activity unfolds at transitions in behavioral arousal state Open
The moment of awakening from sleep reflects a profound transformation in neural activity and behavior. The thalamus is a key controller of arousal state, but whether its diverse nuclei exhibit coordinated or distinct activity at transition…
View article: Vagus Nerve Stimulation using micro-magnetic stimulation
Vagus Nerve Stimulation using micro-magnetic stimulation Open
View article: Planar figure-8 coils for ultra-focal and directional micromagnetic brain stimulation
Planar figure-8 coils for ultra-focal and directional micromagnetic brain stimulation Open
Recently, white-matter fiber tract pathways carrying neural signals through the brain were shown to follow curved, orthogonal grids. This study focuses on how these white-matter fibers may be selectively excited using micromagnetic stimula…
View article: Numerical Simulation of the Radiofrequency Safety of 128-Channel hd-EEG Nets on a 29-Month-Old Whole-Body Model in a 3 Tesla MRI
Numerical Simulation of the Radiofrequency Safety of 128-Channel hd-EEG Nets on a 29-Month-Old Whole-Body Model in a 3 Tesla MRI Open
This study investigates the radiofrequency (RF) induced heating in a pediatric whole-body voxel model with a high-density electroencephalogram (hd-EEG) net during magnetic resonance imaging (MRI) at 3 Tesla. A total of three cases were stu…
View article: Development, validation, and pilot MRI safety study of a high-resolution, open source, whole body pediatric numerical simulation model
Development, validation, and pilot MRI safety study of a high-resolution, open source, whole body pediatric numerical simulation model Open
Numerical body models of children are used for designing medical devices, including but not limited to optical imaging, ultrasound, CT, EEG/MEG, and MRI. These models are used in many clinical and neuroscience research applications, such a…
View article: A Miniaturized Ultra-Focal Magnetic Stimulator and Its Preliminary Application to the Peripheral Nervous System
A Miniaturized Ultra-Focal Magnetic Stimulator and Its Preliminary Application to the Peripheral Nervous System Open
View article: MRI-Induced Heating of Coils for Microscopic Magnetic Stimulation at 1.5 Tesla: An Initial Study
MRI-Induced Heating of Coils for Microscopic Magnetic Stimulation at 1.5 Tesla: An Initial Study Open
In this work, we show with measurements and electromagnetic numerical simulations that the RF-induced increase in local SAR and induced heating during MRI scanning can be greatly reduced by using magnetic stimulation with the proposed μMS …
View article: Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in human sleep
Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in human sleep Open
Fluid dynamics during sleep During non–rapid eye movement sleep, low-frequency oscillations in neural activity support memory consolidation and neuronal computation. Sleep is also associated with increased interstitial fluid volume and cle…
View article: Numerical Simulations of Realistic Lead Trajectories and an Experimental Verification Support the Efficacy of Parallel Radiofrequency Transmission to Reduce Heating of Deep Brain Stimulation Implants during MRI
Numerical Simulations of Realistic Lead Trajectories and an Experimental Verification Support the Efficacy of Parallel Radiofrequency Transmission to Reduce Heating of Deep Brain Stimulation Implants during MRI Open
View article: A microTMS system for peripheral nerve stimulation
A microTMS system for peripheral nerve stimulation Open