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View article: Comparative Effectiveness of Direct Oral Anticoagulants and Warfarin on Venous Thromboembolism in Cancer Patients
Comparative Effectiveness of Direct Oral Anticoagulants and Warfarin on Venous Thromboembolism in Cancer Patients Open
Introduction Venous thromboembolism (VTE) is a leading cause of mortality in cancer patients, and a substantial number of patients are being treated with oral anticoagulants. We aim to assess the comparative effectiveness of direct oral an…
View article: Tranexamic acid in reducing expected blood loss in moderate to low risk surgeries: systematic review, meta-analysis and cost effectiveness analysis
Tranexamic acid in reducing expected blood loss in moderate to low risk surgeries: systematic review, meta-analysis and cost effectiveness analysis Open
Tranexamic acid (TXA) is well-established as a safe intervention for reducing transfusion requirements in surgeries with high-risk for blood loss. However, its role in surgeries classified as low-risk for blood loss remains uncertain. Give…
View article: Policy models for preventative interventions in cardiometabolic diseases: a systematic review
Policy models for preventative interventions in cardiometabolic diseases: a systematic review Open
View article: Correction: The conceptualisation of cardiometabolic disease policy model in the UK
Correction: The conceptualisation of cardiometabolic disease policy model in the UK Open
View article: Mortality in long-term care residents: retrospective national cohort study
Mortality in long-term care residents: retrospective national cohort study Open
Objectives Mortality trends among people living in long-term care settings have been poorly understood. Linking data offers the potential to provide real-world, long-term national follow-up. Our aim was to describe patterns and association…
View article: The conceptualisation of cardiometabolic disease policy model in the UK
The conceptualisation of cardiometabolic disease policy model in the UK Open
View article: Delay and Pay? Healthcare Costs Associated with Late Oral Anti-coagulant Prescribing in People with Atrial Fibrillation
Delay and Pay? Healthcare Costs Associated with Late Oral Anti-coagulant Prescribing in People with Atrial Fibrillation Open
View article: Cost-effectiveness of sentinel screening of endemic diseases alongside malaria diagnosis: A case study in schistosomiasis
Cost-effectiveness of sentinel screening of endemic diseases alongside malaria diagnosis: A case study in schistosomiasis Open
Background In countries where malaria is endemic, the use of rapid diagnostic tests(RDTs) has become routine, especially in rural settings. Such regions are characterised by often having other co-endemic infectious diseases, at high levels…
View article: Understanding Pathways into Care-homes using Data (UnPiCD study): a two-part model to estimate inpatient and care-home costs using national linked health and social care data
Understanding Pathways into Care-homes using Data (UnPiCD study): a two-part model to estimate inpatient and care-home costs using national linked health and social care data Open
Background Pathways into care-homes have been under-researched. Individuals who move-in to a care-home from hospital are clinically distinct from those moving-in from the community. However, it remains unclear whether the source of care-ho…
View article: Evaluating the effect of inequalities in oral anti-coagulant prescribing on outcomes in people with atrial fibrillation
Evaluating the effect of inequalities in oral anti-coagulant prescribing on outcomes in people with atrial fibrillation Open
Aims Whilst anti-coagulation is typically recommended for thromboprophylaxis in atrial fibrillation (AF), it is often never prescribed or prematurely discontinued. The aim of this study was to evaluate the effect of inequalities in anti-co…
View article: The Conceptualization of Cardiometabolic Disease Policy Model in the UK
The Conceptualization of Cardiometabolic Disease Policy Model in the UK Open
Background Decision models are increasingly used to inform the policy-making processes, and there is a need to improve their credibility. The estimation of health and economic outcomes generated from the decision models is influenced by th…
View article: Cardiometabolic Diseases Prevention Policy Models: A Systematic Review to Inform Conceptual Model Development
Cardiometabolic Diseases Prevention Policy Models: A Systematic Review to Inform Conceptual Model Development Open
Background: Cardiometabolic diseases (CMDs) such as cardiovascular disease (CVD) and type 2 diabetes (T2DM) are the leading cause of disability and mortality, as well as contributing to rising healthcare costs worldwide. In order to enhanc…
View article: Evaluating the Effect of Inequalities in Oral Anti-coagulant Prescribing on Outcomes in People with Atrial Fibrillation
Evaluating the Effect of Inequalities in Oral Anti-coagulant Prescribing on Outcomes in People with Atrial Fibrillation Open
Background Whilst anti-coagulation is typically recommended for thromboprophylaxis in atrial fibrillation (AF), it is often never prescribed, or prematurely discontinued, due to concerns regarding bleeding risk. The aim of this study was t…
View article: 1344 UNDERSTANDING PATHWAYS INTO CARE HOMES USING DATA (THE UNPICD STUDY)
1344 UNDERSTANDING PATHWAYS INTO CARE HOMES USING DATA (THE UNPICD STUDY) Open
Introduction Moving into a care home is a significant, life-changing experience which occurs to address care needs which cannot be supported elsewhere. UK health policy recommends against moving into a care home from the acute hospital. Ho…
View article: Understanding Pathways into Care homes using Data (UnPiCD study): a retrospective cohort study using national linked health and social care data
Understanding Pathways into Care homes using Data (UnPiCD study): a retrospective cohort study using national linked health and social care data Open
Background Pathways into care are poorly understood but important life events for individuals and their families. UK policy is to avoid moving-in to care homes from acute hospital settings. This assumes that moves from secondary care repre…
View article: How Least Developed to Lower-Middle Income Countries Use Health Technology Assessment: A Scoping Review
How Least Developed to Lower-Middle Income Countries Use Health Technology Assessment: A Scoping Review Open
Health Technology Assessment (HTA) is a multidisciplinary tool to inform healthcare decision-making. HTA has been implemented in high-income countries (HIC) for several decades but has only recently seen a growing investment in low- and mi…
View article: Propensity score methods for comparative-effectiveness analysis: A case study of direct oral anticoagulants in the atrial fibrillation population
Propensity score methods for comparative-effectiveness analysis: A case study of direct oral anticoagulants in the atrial fibrillation population Open
Objective To explore methodological challenges when using real-world evidence (RWE) to estimate comparative-effectiveness in the context of Health Technology Assessment of direct oral anticoagulants (DOACs) in Scotland. Methods We used lin…
View article: How Least Developed to Lower-Middle Income Countries Use Health Technology Assessment: A Scoping Review
How Least Developed to Lower-Middle Income Countries Use Health Technology Assessment: A Scoping Review Open
Health Technology Assessment (HTA) is a multidisciplinary tool to inform healthcare decision-making. HTA has been implemented in high-income countries (HIC) for several decades but has only recently seen a growing investment in low- and mi…
View article: Emergency department attendance after telephone triage
Emergency department attendance after telephone triage Open
View article: A two-part model to estimate inpatient, outpatient, prescribing and care home costs associated with atrial fibrillation in Scotland
A two-part model to estimate inpatient, outpatient, prescribing and care home costs associated with atrial fibrillation in Scotland Open
Objective This study aimed to estimate global inpatient, outpatient, prescribing and care home costs for patients with atrial fibrillation using population-based, individual-level linked data. Design A two-part model was employed to estima…
View article: PND96 COMPARISON OF PROPENSITY SCORE METHODS A CASE STUDY OF DIRECT ORAL ANTICOAGULANTS
PND96 COMPARISON OF PROPENSITY SCORE METHODS A CASE STUDY OF DIRECT ORAL ANTICOAGULANTS Open
View article: The role of real-world evidence in health technology assessment: a case study of direct oral anticoagulants in the atrial fibrillation population
The role of real-world evidence in health technology assessment: a case study of direct oral anticoagulants in the atrial fibrillation population Open
Real-World Evidence (RWE) refers to any “data used for decision-making that are not collected in conventional Randomised Controlled Trials (RCTs), and is increasingly used in Health Technology Assessment (HTA) as an adjustment to the evide…
View article: The inpatient, outpatient and social care costs associated with atrial fibrillation in Scotland: a record linkage study
The inpatient, outpatient and social care costs associated with atrial fibrillation in Scotland: a record linkage study Open
BackgroundAtrial Fibrillation (AF) is a highly debilitating condition with significant economic burden. Previous studies have estimated the cost of hospitalisations associated with AF in Scotland. However, patients with AF are often elderl…
View article: Is Regenerative Medicine Cost-Effective? Evidences From The First Approved Stem Cell Based Product
Is Regenerative Medicine Cost-Effective? Evidences From The First Approved Stem Cell Based Product Open
View article: Cost-effectiveness analysis of Ex-Vivo expanded Autologous Corneal Epithelial Cells containing Stem Cells to repair the damaged ocular surface in Patients with moderate to severe Limbal Stem Cell deficiency due to Ocular Burns in the UK
Cost-effectiveness analysis of Ex-Vivo expanded Autologous Corneal Epithelial Cells containing Stem Cells to repair the damaged ocular surface in Patients with moderate to severe Limbal Stem Cell deficiency due to Ocular Burns in the UK Open