Giorgio Perilongo
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View article: EEG difference in the Higuchi fractal dimension of wakefulness and sleep from birth to adolescence
EEG difference in the Higuchi fractal dimension of wakefulness and sleep from birth to adolescence Open
Brain maturation from birth to adolescence involves profound transformations in neural dynamics, which can be studied in a minimally invasive manner using quantitative EEG. Most of the results published in the literature are based on spect…
View article: Improving Medication Safety Through Medication Reconciliation in Pediatric Neurology: Clinical Pharmacist Recommendations and Physician Uptake in a 13-Week Study
Improving Medication Safety Through Medication Reconciliation in Pediatric Neurology: Clinical Pharmacist Recommendations and Physician Uptake in a 13-Week Study Open
Background/Objectives: Clinical pharmacy plays a crucial role in optimizing medication use, particularly in pediatric settings where drug therapy can be complex and understudied. This study aims to assess the impact of clinical pharmacists…
View article: Medication Reconciliation in Pediatric Neurology: A Longitudinal Study of Clinical Pharmacist Recommendations and Physician Acceptance Dynamics
Medication Reconciliation in Pediatric Neurology: A Longitudinal Study of Clinical Pharmacist Recommendations and Physician Acceptance Dynamics Open
Background/Objectives: Clinical pharmacy plays a crucial role in optimizing medication use, particularly in pediatric settings where drug therapy can be complex and understudied. This study aims to assess the impact of clinical pharmacists…
View article: Adolescent gender dysphoria management: position paper from the Italian Academy of Pediatrics, the Italian Society of Pediatrics, the Italian Society for Pediatric Endocrinology and Diabetes, the Italian Society of Adolescent Medicine and the Italian Society of Child and Adolescent Neuropsychiatry
Adolescent gender dysphoria management: position paper from the Italian Academy of Pediatrics, the Italian Society of Pediatrics, the Italian Society for Pediatric Endocrinology and Diabetes, the Italian Society of Adolescent Medicine and the Italian Society of Child and Adolescent Neuropsychiatry Open
View article: Present and future are getting confused: are we equipped to face the technological revolution?
Present and future are getting confused: are we equipped to face the technological revolution? Open
View article: Nurturing the next generation of pediatric physician scientists: the Padova Physician Scientist Research Training for pediatric residents
Nurturing the next generation of pediatric physician scientists: the Padova Physician Scientist Research Training for pediatric residents Open
View article: Vaccination practices in pediatric transplantation: A survey among member centers of the European reference network <scp>TransplantChild</scp>
Vaccination practices in pediatric transplantation: A survey among member centers of the European reference network <span>TransplantChild</span> Open
Background There is considerable variation in vaccination practices between pediatric transplant centers. This study aims to evaluate active immunization attitudes and practices among ERN‐TransplantChild centers and identify potential area…
View article: Efficacy and safety of ketamine for neonatal refractory status epilepticus: case report and systematic review
Efficacy and safety of ketamine for neonatal refractory status epilepticus: case report and systematic review Open
Background Evidence-based data on treatment of neonatal status epilepticus (SE) are scarce. We aimed to collect data on the efficacy and safety of ketamine for the treatment of neonatal SE and to assess its possible role in the treatment o…
View article: A pilot study on sports activities in pediatric palliative care: just do it
A pilot study on sports activities in pediatric palliative care: just do it Open
Background There has been a growing interest in studying the value of physical exercise in children with disabilities or chronic health conditions because of evidence of improvement in quality of life, social acceptance, and physical funct…
View article: Macromolecular crowding tuned extracellular matrix deposition in a bioprinted human rhabdomyosarcoma model
Macromolecular crowding tuned extracellular matrix deposition in a bioprinted human rhabdomyosarcoma model Open
View article: Pediatric Preventive Care in Middle-High Resource Countries—The Padova Chart for Health in Children
Pediatric Preventive Care in Middle-High Resource Countries—The Padova Chart for Health in Children Open
Importance The Padova Chart for Health in Children (PCHC) aims to gather the evidence of healthcare promotion and protection for chidren and adolescents (i.e., aged <18 y) into a single document in order to guide families, healthcare pr…
View article: Pediatric Palliative Care in Oncology: Basic Principles
Pediatric Palliative Care in Oncology: Basic Principles Open
About 4 million children with an oncological disease worldwide require pediatric palliative care (PPC) due to the nature of their condition. PPC is not limited to end-of-life care; it is a general approach continuing over the entire diseas…
View article: The Intervention Areas of the Psychologist in Pediatric Palliative Care: A Retrospective Analysis
The Intervention Areas of the Psychologist in Pediatric Palliative Care: A Retrospective Analysis Open
Infants, children and adolescents with life-limiting and life-threatening disease need long-term care that may change according to disease’s natural history. With the primary goal of quality of life, the psychologist of pediatric palliativ…
View article: Protective SARS-CoV-2 Antibody Response in Children With Inflammatory Bowel Disease
Protective SARS-CoV-2 Antibody Response in Children With Inflammatory Bowel Disease Open
Background To date, there's no evidence of an increased risk of SARS-CoV-2 infection or more severe COVID-19 in patients with inflammatory bowel disease (IBD). However, whether COVID-19 alters the clinical course of IBD or whether IBD trea…
View article: Case Report: Intestinal Nodular Lymphoid Hyperplasia as First Manifestation of Activated PI3Kδ Syndrome Due to a Novel PIK3CD Variant
Case Report: Intestinal Nodular Lymphoid Hyperplasia as First Manifestation of Activated PI3Kδ Syndrome Due to a Novel PIK3CD Variant Open
Nodular lymphoid hyperplasia (NLH) is a lymphoproliferative disease caused by non-clonal expansion of lymphoid cells in the gut mucosa. Little is known about the pathogenesis of NLH, which is often disregarded as an insignificant or para-p…
View article: IFIH1 loss-of-function variants contribute to very early-onset inflammatory bowel disease
IFIH1 loss-of-function variants contribute to very early-onset inflammatory bowel disease Open
View article: Novel CARMIL2 loss-of-function variants are associated with pediatric inflammatory bowel disease
Novel CARMIL2 loss-of-function variants are associated with pediatric inflammatory bowel disease Open
CARMIL2 is required for CD28-mediated co-stimulation of NF-κB signaling in T cells and its deficiency has been associated with primary immunodeficiency and, recently, very early onset inflammatory bowel disease (IBD). Here we describe the …
View article: Do we always need to treat patients with spinal muscular atrophy? A personal view and experience
Do we always need to treat patients with spinal muscular atrophy? A personal view and experience Open
View article: Intratracheal administration of mesenchymal stem cell-derived extracellular vesicles reduces lung injuries in a chronic rat model of bronchopulmonary dysplasia
Intratracheal administration of mesenchymal stem cell-derived extracellular vesicles reduces lung injuries in a chronic rat model of bronchopulmonary dysplasia Open
Early therapeutic effect of intratracheally (IT)-administered extracellular vesicles secreted by mesenchymal stem cells (MSC-EVs) has been demonstrated in a rat model of bronchopulmonary dysplasia (BPD) involving hyperoxia exposure in the …
View article: Children's Hospital Management in the COVID-19 Era: The Reorganization of a Tertiary Care Pediatric Emergency Department in Northern Italy
Children's Hospital Management in the COVID-19 Era: The Reorganization of a Tertiary Care Pediatric Emergency Department in Northern Italy Open
In the Veneto Region, an exponential spread of patients affected by 2019 novel Coronavirus disease (COVID-19) has been observed after February 21st. Since then, we have been evaluating children suspected or confirmed for SARS-CoV-2 infecti…
View article: Introduction
Introduction Open
View article: Pediatric Central Nervous System Tumors as Phenotypic Manifestation of Cancer Predisposition Syndromes
Pediatric Central Nervous System Tumors as Phenotypic Manifestation of Cancer Predisposition Syndromes Open
View article: COVID-19 Pandemic: Perspective of an Italian Tertiary Care Pediatric Center
COVID-19 Pandemic: Perspective of an Italian Tertiary Care Pediatric Center Open
Since February 2020, Italy has been faced with the dramatic spread of novel Coronavirus SARS-CoV-2. This impetuous pandemic infection forced many hospitals to reorganize their healthcare systems. Predicting a rapid spread of the SARS-CoV-2…
View article: Mesenchymal stromal cells and their secreted extracellular vesicles as therapeutic tools for COVID-19 pneumonia?
Mesenchymal stromal cells and their secreted extracellular vesicles as therapeutic tools for COVID-19 pneumonia? Open
View article: Present and Future of Bronchopulmonary Dysplasia
Present and Future of Bronchopulmonary Dysplasia Open
Bronchopulmonary dysplasia (BPD) is the most common respiratory disorder among infants born extremely preterm. The pathogenesis of BPD involves multiple prenatal and postnatal mechanisms affecting the development of a very immature lung. T…
View article: The importance of age as prognostic factor for the outcome of patients with hepatoblastoma: Analysis from the Children's Hepatic tumors International Collaboration (CHIC) database
The importance of age as prognostic factor for the outcome of patients with hepatoblastoma: Analysis from the Children's Hepatic tumors International Collaboration (CHIC) database Open
Purpose Treatment outcomes for hepatoblastoma have improved markedly in the contemporary treatment era, principally due to therapy intensification, with overall survival increasing from 35% in the 1970s to 90% at present. Unfortunately, th…
View article: Cross-cutting view of current challenges in paediatric solid organ and haematopoietic stem cell transplantation in Europe: the European Reference Network TransplantChild
Cross-cutting view of current challenges in paediatric solid organ and haematopoietic stem cell transplantation in Europe: the European Reference Network TransplantChild Open
The low prevalence of European paediatric transplanted patients and scarcity of resources and expertise led to the need for a multidisciplinary network able to improve the quality of life of paediatric patients and families requiring a sol…
View article: Comparison of Different Methods to Isolate Urinary Extracellular Vesicles Useful as Possible Kidney Damage Biomarkers
Comparison of Different Methods to Isolate Urinary Extracellular Vesicles Useful as Possible Kidney Damage Biomarkers Open
View article: In Memoriam: Giulio D'Angio, MD, May 2, 1922-September 14, 2018
In Memoriam: Giulio D'Angio, MD, May 2, 1922-September 14, 2018 Open
View article: Giulio (Dan) J. D’Angio, MD (1922–2018)
Giulio (Dan) J. D’Angio, MD (1922–2018) Open