Giorgio Piaggio
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View article: IgM hyposialylation drives podocyte injury in pediatric and young adult patients with podocytopathies
IgM hyposialylation drives podocyte injury in pediatric and young adult patients with podocytopathies Open
Introduction Altered immunoglobulin glycosylation has been implicated in antibody-mediated podocytopathies, yet the functional impact of IgM sialylation remains unclear. Previous evidence suggested that circulating cationic or hyposialylat…
View article: Single-center results from the first 100 robotic ureteral reimplantation in children: analysis of learning curve effects
Single-center results from the first 100 robotic ureteral reimplantation in children: analysis of learning curve effects Open
Introduction Robot-assisted laparoscopic ureteral reimplantation (RALUR) is increasingly utilized in pediatric urology, yet outcomes vary widely and the learning curve remains under-investigated. This study aims to evaluate perioperative o…
View article: Afucosylated IgG in idiopathic nephrotic syndrome patients with anti-nephrin autoantibodies correlate with disease activity
Afucosylated IgG in idiopathic nephrotic syndrome patients with anti-nephrin autoantibodies correlate with disease activity Open
View article: Abscess formation within brain metastasis
Abscess formation within brain metastasis Open
Background: Brain abscesses are a potentially curable but life-threatening medical condition. Their occurrence within brain metastases has been exceptionally reported. In this study, we describe in detail this rare entity. Case Description…
View article: Etiology and Oral Antibiotic Susceptibility Patterns of the First Urinary Tract Infection Episode in Infants Under 6 Months of Age: A 17-Year, Retrospective, Single-Center Study in Italy
Etiology and Oral Antibiotic Susceptibility Patterns of the First Urinary Tract Infection Episode in Infants Under 6 Months of Age: A 17-Year, Retrospective, Single-Center Study in Italy Open
Background: Urinary tract infections (UTIs) are among the most common bacterial infections in children, and the antibiotic susceptibility in the youngest patients remains poorly understood. This study aimed to describe the distribution of …
View article: Afucosylated IgG in Idiopathic Nephrotic Syndrome Patients with Anti-Nephrin Autoantibodies Correlate with Disease Activity
Afucosylated IgG in Idiopathic Nephrotic Syndrome Patients with Anti-Nephrin Autoantibodies Correlate with Disease Activity Open
View article: Diffusion-weighted MRI in the identification of renal parenchymal involvement in children with a first episode of febrile urinary tract infection
Diffusion-weighted MRI in the identification of renal parenchymal involvement in children with a first episode of febrile urinary tract infection Open
Aims This study aims to assess the diagnostic accuracy of diffusion-weighted Magnetic Resonance Imaging (DW-MRI) and determine the inter-reader agreement between two expert radiologists in detecting pyelonephritic foci during the initial e…
View article: Functional Magnetic Resonance Urography in Ureteropelvic Junction Obstruction: Proposal for a Pediatric Quantitative Score
Functional Magnetic Resonance Urography in Ureteropelvic Junction Obstruction: Proposal for a Pediatric Quantitative Score Open
Background: Ureteropelvic junction obstruction (UPJO) is one of the most frequent causes of congenital hydronephrosis. It is essential to distinguish UPJO which needs surgical treatment. fMRU combines high quality morphological details of …
View article: Epidemiology of Antibiotic Resistant Pathogens in Pediatric Urinary Tract Infections as a Tool to Develop a Prediction Model for Early Detection of Drug-Specific Resistance
Epidemiology of Antibiotic Resistant Pathogens in Pediatric Urinary Tract Infections as a Tool to Develop a Prediction Model for Early Detection of Drug-Specific Resistance Open
Antibiotic resistance is an increasing problem, especially in children with urinary tract infections. Rates of drug-specific resistant pathogens were reported, and an easy prediction model to guide the clinical decision-making process for …
View article: Kidney Involvement in PSTPIP1 Associated Inflammatory Diseases (PAID): A Case Report and Review of the Literature
Kidney Involvement in PSTPIP1 Associated Inflammatory Diseases (PAID): A Case Report and Review of the Literature Open
Pyogenic arthritis, pyoderma gangrenosum and acne (PAPA) syndrome, and the proline-serine-threonine phosphatase-interacting protein 1 (PSTPIP1)-associated myeloid-related proteinemia inflammatory (PAMI) syndrome are two distinct clinical c…
View article: Refractory Minimal Change Disease and Focal Segmental Glomerular Sclerosis Treated With Anakinra
Refractory Minimal Change Disease and Focal Segmental Glomerular Sclerosis Treated With Anakinra Open
Idiopathic nephrotic syndrome (NS) is the most common cause of proteinuria in children and young adults. Minimal lesion with fusion of slit-diaphragm is the pathologic substrate in most cases,1 whereas focal segmental glomerular sclerosis …
View article: Copy Number Variant Analysis and Genome-wide Association Study Identify Loci with Large Effect for Vesicoureteral Reflux
Copy Number Variant Analysis and Genome-wide Association Study Identify Loci with Large Effect for Vesicoureteral Reflux Open
Significance Statement Vesicoureteral reflux (VUR) is associated with progressive kidney disease. Familial aggregation supports a hereditary basis; however, its genetic architecture remains to be elucidated. The largest VUR copy number var…
View article: Author Correction: The copy number variation landscape of congenital anomalies of the kidney and urinary tract
Author Correction: The copy number variation landscape of congenital anomalies of the kidney and urinary tract Open
View article: The copy number variation landscape of congenital anomalies of the kidney and urinary tract
The copy number variation landscape of congenital anomalies of the kidney and urinary tract Open
View article: Adverse events linked with the use of chimeric and humanized anti‐CD20 antibodies in children with idiopathic nephrotic syndrome
Adverse events linked with the use of chimeric and humanized anti‐CD20 antibodies in children with idiopathic nephrotic syndrome Open
Aims Anti‐CD20 antibodies are increasingly being used to treat idiopathic nephrotic syndrome (INS) in children. While they may allow steroid and calcineurin inhibitor withdrawal, repeated infusions of anti‐CD20 antibodies are often require…