Giovanna Liguori
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View article: The Phenomenon of Antimicrobial Resistance in Southern Italy: An Overview of the Current Situation
The Phenomenon of Antimicrobial Resistance in Southern Italy: An Overview of the Current Situation Open
Purpose: Antimicrobial resistance (AMR) is an escalating public health threat globally, with Southern Italy presenting distinct challenges that warrant targeted investigation. This study aims to assess the prevalence and characteristics of…
View article: The Impact of Environmental PCB Exposure on IVF Outcomes: Exploring the Relationship between Specific Congeners and Abortion Rates in Women from Varying Pollution Zones.Affiliations
The Impact of Environmental PCB Exposure on IVF Outcomes: Exploring the Relationship between Specific Congeners and Abortion Rates in Women from Varying Pollution Zones.Affiliations Open
Background Although the production of polychlorinated biphenyls (PCBs) ceased in 1977, human exposure persists. This may have adverse effects on reproductive health, including reduced fertility and increased abortion risk. However, human d…
View article: Honeybee Sentience: Scientific Evidence and Implications for EU Animal Welfare Policy
Honeybee Sentience: Scientific Evidence and Implications for EU Animal Welfare Policy Open
The growing recognition of animal sentience has led to notable progress in European Union animal welfare legislation. However, a significant inconsistency remains: while mammals, birds, and cephalopods are legally protected as sentient bei…
View article: The New Frontier in Small-Cell Lung Cancer: Can Atezolizumab Ensure Enduring Stability?
The New Frontier in Small-Cell Lung Cancer: Can Atezolizumab Ensure Enduring Stability? Open
Small-cell lung cancer (SCLC) is an aggressive malignancy with poor prognosis despite initial responsiveness to chemotherapy. Platinum-based chemotherapy with etoposide has long been the standard first-line treatment, but recent advances i…
View article: An Organizational Model of a Food Production Chain: A Case Study in the Poultry Sector in Foggia (Italy)
An Organizational Model of a Food Production Chain: A Case Study in the Poultry Sector in Foggia (Italy) Open
The purpose of this study was to analyze the poultry chain in southern Italy to describe the characteristics of farms and their locations and to propose an optimized organizational model with a broader approach that considers not only econ…
View article: Green Veterinary Pharmacology Applied to Beekeeping: Semi-Field and Field Tests Against Varroa destructor, Using Essential Oil of Bergamot (Citrus bergamia) and Lemon (Citrus limon)
Green Veterinary Pharmacology Applied to Beekeeping: Semi-Field and Field Tests Against Varroa destructor, Using Essential Oil of Bergamot (Citrus bergamia) and Lemon (Citrus limon) Open
Varroa destructor is an ectoparasitic mite that causes a true syndrome with complex symptoms in honeybees. For mite control, several synthetic active principles are commercially available. However, these formulations are proving less effec…
View article: Polycyclic Aromatic Hydrocarbons (PAHs) in the Environment: Occupational Exposure, Health Risks and Fertility Implications
Polycyclic Aromatic Hydrocarbons (PAHs) in the Environment: Occupational Exposure, Health Risks and Fertility Implications Open
Polycyclic aromatic hydrocarbons (PAHs) are a group of organic compounds with fused aromatic rings, primarily derived from combustion processes and environmental pollutants. This narrative review discusses the most relevant studies on PAHs…
View article: Antimicrobial Properties of Hive Products and Their Potential Applications in Human and Veterinary Medicine
Antimicrobial Properties of Hive Products and Their Potential Applications in Human and Veterinary Medicine Open
Hive products, encompassing honey, propolis, bee venom, royal jelly, and pollen, are recognized for their antimicrobial and therapeutic properties. This review examines their chemical composition, explores their mechanisms of action, and d…
View article: Acanthamoeba keratitis in Northern Italy: three-year experience with an integrated clinical and diagnostic workflow
Acanthamoeba keratitis in Northern Italy: three-year experience with an integrated clinical and diagnostic workflow Open
View article: Understanding Environmental Contamination Through the Lens of the Peregrine Falcon (Falco peregrinus)
Understanding Environmental Contamination Through the Lens of the Peregrine Falcon (Falco peregrinus) Open
The peregrine falcon (Falco peregrinus) stands out as a crucial sentinel species for assessing environmental contamination, owing to its widespread distribution, high position in the food chain, and susceptibility to pollutants. As apex pr…
View article: Liquid biopsy-based technologies: a promising tool for biomarker identification in her2-low breast cancer patients for improved therapeutic outcomes
Liquid biopsy-based technologies: a promising tool for biomarker identification in her2-low breast cancer patients for improved therapeutic outcomes Open
The molecular classification of breast cancer plays a pivotal role in developing personalized treatment strategies, with the aim of improving therapeutic outcomes. Despite significant advancements, current diagnostic workflows are hindered…
View article: Hepatitis E and Potential Public Health Implications from a One-Health Perspective: Special Focus on the European Wild Boar (Sus scrofa)
Hepatitis E and Potential Public Health Implications from a One-Health Perspective: Special Focus on the European Wild Boar (Sus scrofa) Open
The hepatitis E virus (HEV) has become increasingly important in recent years in terms of risk for public health, as the main causative agent of acute viral hepatitis. It is a foodborne disease transmitted to humans through the consumption…
View article: Antimicrobial Resistance in Livestock: A Serious Threat to Public Health
Antimicrobial Resistance in Livestock: A Serious Threat to Public Health Open
Antimicrobial resistance represents an alarming public health problem; its importance is related to the significant clinical implications (increased morbidity, mortality, disease duration, development of comorbidities, and epidemics), as w…
View article: Hive Products: Composition, Pharmacological Properties, and Therapeutic Applications
Hive Products: Composition, Pharmacological Properties, and Therapeutic Applications Open
Beekeeping provides products with nutraceutical and pharmaceutical characteristics. These products are characterized by abundance of bioactive compounds. For different reasons, honey, royal jelly, propolis, venom, and pollen are beneficial…
View article: A Comparative Analysis of Orexins in the Physio-Pathological Processes of the Male Genital Tract: New Challenges? A Review
A Comparative Analysis of Orexins in the Physio-Pathological Processes of the Male Genital Tract: New Challenges? A Review Open
Orexins A (OXA) and B (OXB) and their specific receptors, receptor 1 (OX1R) and 2 (OX2R) for orexins, are hypothalamic peptides involved in orchestrating several functions in the central nervous system and peripheral organs, including slee…
View article: Re-emergence of human leishmaniasis in northern Italy, 2004 to 2022: a retrospective analysis
Re-emergence of human leishmaniasis in northern Italy, 2004 to 2022: a retrospective analysis Open
Background Human leishmaniasis is a protozoan disease transmitted by sand flies and endemic in the Mediterranean region. In Italy, leishmaniasis is present in the south and the western coastal regions, with an epidemic peak detected in nor…
View article: G Protein-Coupled Estrogen Receptor (GPER) and ERs Are Modulated in the Testis–Epididymal Complex in the Normal and Cryptorchid Dog
G Protein-Coupled Estrogen Receptor (GPER) and ERs Are Modulated in the Testis–Epididymal Complex in the Normal and Cryptorchid Dog Open
There is growing evidence by the literature that the unbalance between androgens and estrogens is a relevant condition associated with a common canine reproductive disorder known as cryptorchidism. The role of estrogens in regulating testi…
View article: Orexins and Prostate Cancer: State of the Art and Potential Experimental and Therapeutic Perspectives
Orexins and Prostate Cancer: State of the Art and Potential Experimental and Therapeutic Perspectives Open
Prostate cancer (PCa) is the second most common cancer in humans. Peptides have recently been used as targeted therapeutics in cancers, due to their extensive multi-functional applications. Two hypothalamic peptides, orexins A (OXA) and B …
View article: Human-Animal Interaction in Animal-Assisted Interventions (AAI)s: Zoonosis Risks, Benefits, and Future Directions—A One Health Approach
Human-Animal Interaction in Animal-Assisted Interventions (AAI)s: Zoonosis Risks, Benefits, and Future Directions—A One Health Approach Open
Animal-assisted interventions (AAI)s represent the expression of integrated medicine, according to the One Health approach. Actually, animal-assisted therapies and animal-assisted activities are implemented in hospitals, rehabilitation cen…
View article: Does Orexin B-Binding Receptor 2 for Orexins Regulate Testicular and Epididymal Functions in Normal and Cryptorchid Dogs?
Does Orexin B-Binding Receptor 2 for Orexins Regulate Testicular and Epididymal Functions in Normal and Cryptorchid Dogs? Open
Orexins A (OXA) and B (OXB) and the receptors 1 (OX1R) and 2 (OX2R) for orexins are hypothalamic peptides found in several mammalian organs and participated to the control of a wide assortment of physiological and pathological functions. T…
View article: Urology practice during the COVID-19 vaccination campaign
Urology practice during the COVID-19 vaccination campaign Open
View article: A large outbreak of giardiasis in a municipality of the Bologna province, north-eastern Italy, November 2018 to April 2019
A large outbreak of giardiasis in a municipality of the Bologna province, north-eastern Italy, November 2018 to April 2019 Open
Giardiasis, the disease caused by the flagellate Giardia duodenalis (syn. G.lamblia, G. intestinalis ), is the most commonly reported among the five food- and waterborne parasitic diseases under mandatory surveillance in 24 EU countries. F…
View article: Are nutrition and physical activity associated with gut microbiota? A pilot study on a sample of healthy young adults.
Are nutrition and physical activity associated with gut microbiota? A pilot study on a sample of healthy young adults. Open
These preliminary results suggest the association between physical activity and gut microbiota composition in healthy humans.
View article: Aquaporins Are Differentially Regulated in Canine Cryptorchid Efferent Ductules and Epididymis
Aquaporins Are Differentially Regulated in Canine Cryptorchid Efferent Ductules and Epididymis Open
The efferent ductules and the epididymis are parts of the male reproductive system where spermatozoa mature. Specialized epithelial cells in these ducts contribute to the transport of fluids produced by spermatozoa’s metabolic activity. Aq…
View article: Do Animals Play a Role in the Transmission of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)? A Commentary
Do Animals Play a Role in the Transmission of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)? A Commentary Open
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) belongs to the Beta-coronavirus genus. It is 96.2% homologous to bat CoV RaTG13 and 88% homologous to two bat SARS-like coronaviruses. SARS-CoV-2 is the infectious agent responsi…
View article: Exploring the association between physical activity and gut microbiota composition: a review of current evidence.
Exploring the association between physical activity and gut microbiota composition: a review of current evidence. Open
The gut microbiota is implicated in digestive, metabolic and immune processes of the host. The physiological and pathophysiological functions of the intestinal microbiota depend of its composition, and several individual or external factor…
View article: Orexin A-Mediated Modulation of Reproductive Activities in Testis of Normal and Cryptorchid Dogs: Possible Model for Studying Relationships Between Energy Metabolism and Reproductive Control
Orexin A-Mediated Modulation of Reproductive Activities in Testis of Normal and Cryptorchid Dogs: Possible Model for Studying Relationships Between Energy Metabolism and Reproductive Control Open
Orexin A (OxA) is a neuropeptide produced in the lateral hypothalamus that performs pleiotropic functions in different tissues, including involvement in energy homeostasis and reproductive neuroendocrine functions. The role of OxA is parti…
View article: Urocortins in the mammalian endocrine system
Urocortins in the mammalian endocrine system Open
Urocortins (Ucns), peptides belonging to the corticotropin-releasing hormone (CRH) family, are classified into Ucn1, Ucn2, and Ucn3. They are involved in regulating several body functions by binding to two G protein-coupled receptors: rece…
View article: Potential role of orexin A binding the receptor 1 for orexins in normal and cryptorchid dogs
Potential role of orexin A binding the receptor 1 for orexins in normal and cryptorchid dogs Open
View article: First study on the peptidergic innervation of the brain superior sagittal sinus in humans
First study on the peptidergic innervation of the brain superior sagittal sinus in humans Open
The superior sagittal sinus (SSS) of the mammalian brain is a pain-sensitive intracranial vessel thought to play a role in the pathogenesis of migraine headaches. Here, we aimed to investigate the presence and the potential co-localization…