Giovanni Barbanti Bròdano
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View article: Vertebral bone marrow clot breakthrough: a powerful osteogenic and antibacterial scaffold for spinal fusion surgery
Vertebral bone marrow clot breakthrough: a powerful osteogenic and antibacterial scaffold for spinal fusion surgery Open
Achieving solid arthrodesis while minimizing postoperative infections remains a critical challenge in spinal fusion surgery. Clotted bone marrow aspirate (BMA) has emerged as promising tools to enhance bone fusion, yet their antimicrobial …
View article: The Roof Technique in the Treatment of Bone Tumors of the Spine. A Ten Years’ Experience
The Roof Technique in the Treatment of Bone Tumors of the Spine. A Ten Years’ Experience Open
Introduction: Besides appropriate oncological principles for resection, spine tumors require complex reconstructive techniques in a setting of biologic compromise. Fusion outcomes in this cohort are influenced by several variables. Most pr…
View article: Evaluation of Adverse Events and the Impact on Health-Related Outcomes in Patients Undergoing Surgery for Metastatic Spine Tumors: Analysis of the Metastatic Tumor Research and Outcomes Network (MTRON) Registry Dataset
Evaluation of Adverse Events and the Impact on Health-Related Outcomes in Patients Undergoing Surgery for Metastatic Spine Tumors: Analysis of the Metastatic Tumor Research and Outcomes Network (MTRON) Registry Dataset Open
Study Design This study is part of the AO Spine Metastatic Tumor Research and Outcomes Network [MTRON], an international multicenter prospective observational registry including patients with spinal metastases. Objectives This study aims t…
View article: Decompression-Only for Lumbar Degenerative Spondylolisthesis - What are the Risk for Failure? - A Systematic Review
Decompression-Only for Lumbar Degenerative Spondylolisthesis - What are the Risk for Failure? - A Systematic Review Open
Study Design Systematic review. Objective The current literature suggests that decompression-only procedures may be an adequate treatment option for low-grade degenerative spondylolisthesis. It is necessary to understand the causes of the …
View article: Surgical Management of Sacral Bone Tumors: A Retrospective Analysis of Outcomes, Complications, and Survival
Surgical Management of Sacral Bone Tumors: A Retrospective Analysis of Outcomes, Complications, and Survival Open
Background: Primary malignant bone tumors are exceedingly rare, with an incidence of 0.5 to 1 per million, and sacral localization is even more uncommon, representing only 1–3.5% of these tumors. These malignancies are often diagnosed late…
View article: Health- related quality of life after surgery for spinal metastases
Health- related quality of life after surgery for spinal metastases Open
This study confirms the effectiveness of surgery for spinal metastases in improving patients' performance status and demonstrates an overall improvement in HRQOL, which is maintained over time.
View article: Correction: Lana et al. Evolution and Innovations in Bone Marrow Cellular Therapy for Musculoskeletal Disorders: Tracing the Historical Trajectory and Contemporary Advances. Bioengineering 2024, 11, 979
Correction: Lana et al. Evolution and Innovations in Bone Marrow Cellular Therapy for Musculoskeletal Disorders: Tracing the Historical Trajectory and Contemporary Advances. Bioengineering 2024, 11, 979 Open
In the original publication [...]
View article: Experimental ex vivo characterization of the biomechanical effects of laminectomy and posterior fixation of the lumbo-sacral spine
Experimental ex vivo characterization of the biomechanical effects of laminectomy and posterior fixation of the lumbo-sacral spine Open
View article: Health-related quality of life in patients treated with en bloc resection for primary tumors of the spine
Health-related quality of life in patients treated with en bloc resection for primary tumors of the spine Open
Study design Retrospective analysis Objective The aim of this study is to evaluate the functional outcomes and the health-related quality of life (HRQOL) in patients undergoing en bloc resection of spinal tumor. Summary of background data …
View article: Evolution and Innovations in Bone Marrow Cellular Therapy for Musculoskeletal Disorders: Tracing the Historical Trajectory and Contemporary Advances
Evolution and Innovations in Bone Marrow Cellular Therapy for Musculoskeletal Disorders: Tracing the Historical Trajectory and Contemporary Advances Open
Bone marrow cellular therapy has undergone a remarkable evolution, significantly impacting the treatment of musculoskeletal disorders. This review traces the historical trajectory from early mythological references to contemporary scientif…
View article: Prolonged operative time significantly impacts on the incidence of complications in spinal surgery
Prolonged operative time significantly impacts on the incidence of complications in spinal surgery Open
View article: Prolonged Operative Time Significantly Impacts on the Incidence of Complications in Spinal Surgery
Prolonged Operative Time Significantly Impacts on the Incidence of Complications in Spinal Surgery Open
Background In spinal surgery adverse events (AE) and surgical complications (SC) significantly affect patient’s outcome and quality of life. The duration of surgery has been investigated in different surgical field as risk factor for compl…
View article: Effect of two-level decompressive procedures on the biomechanics of the lumbo-sacral spine: an ex vivo study
Effect of two-level decompressive procedures on the biomechanics of the lumbo-sacral spine: an ex vivo study Open
Hemilaminectomy and laminectomy are decompressive procedures commonly used in case of lumbar spinal stenosis, which involve the removal of the posterior elements of the spine. These procedures may compromise the stability of the spine segm…
View article: Capacitive biophysical stimulation improves the healing of vertebral fragility fractures: a prospective multicentre randomized controlled trial
Capacitive biophysical stimulation improves the healing of vertebral fragility fractures: a prospective multicentre randomized controlled trial Open
View article: Surgeon Preference Regarding Wound Dressing Management in Lumbar Fusion Surgery: An AO Spine Global Cross-Sectional Study
Surgeon Preference Regarding Wound Dressing Management in Lumbar Fusion Surgery: An AO Spine Global Cross-Sectional Study Open
Objective: To evaluate the global practice pattern of wound dressing use after lumbar fusion for degenerative conditions.Methods: A survey issued by AO Spine Knowledge Forums Deformity and Degenerative was sent out to AO Spine members. The…
View article: Factors associated with increased length of stay and risk of complications in 336 patients submitted to spine surgery. The role of a validated capture system (SAVES v2) as a first-line tool to properly face the problem
Factors associated with increased length of stay and risk of complications in 336 patients submitted to spine surgery. The role of a validated capture system (SAVES v2) as a first-line tool to properly face the problem Open
Purpose In this study, we analyzed the use of a validated capture system (Spinal Adverse Events Severity system, SAVES V2) as a first non-technical skill to properly face the relevant problem of surgical complications (SCs) and adverse eve…
View article: Combining 3D Printing and Cryostructuring to Tackle Infection and Spine Fusion
Combining 3D Printing and Cryostructuring to Tackle Infection and Spine Fusion Open
Low back pain is among the main issues in vertebral orthopaedics. Intervertebral disk degeneration can be severe, up to requiring the replacement of the damaged disk by substitutes to achieve spine fusion. Disk removal results in critical …
View article: Safety and efficacy of autologous bone marrow clot as a multifunctional bioscaffold for instrumental posterior lumbar fusion: a 1-year follow-up pilot study
Safety and efficacy of autologous bone marrow clot as a multifunctional bioscaffold for instrumental posterior lumbar fusion: a 1-year follow-up pilot study Open
Background Bone marrow aspirate (BMA), when combined with graft substitutes, has long been introduced as a promising alternative to iliac crest bone graft in spinal fusion. However, the use of BMA is limited by the absence of a standardize…
View article: Effect of laminectomy and posterior fixation on the biomechanics of the lumbar spine: an ex-vivo study
Effect of laminectomy and posterior fixation on the biomechanics of the lumbar spine: an ex-vivo study Open
View article: Correlation Between Sagittal Balance and Mechanical Distal Junctional Failure in Degenerative Pathology of the Spine: A Retrospective Analysis
Correlation Between Sagittal Balance and Mechanical Distal Junctional Failure in Degenerative Pathology of the Spine: A Retrospective Analysis Open
Study design Retrospective cohort study. Objectives This study aimed to investigate the failure of the caudal end of lumbar posterior fixation in terms of pre-operative and post-operative spinopelvic parameters, correction performed, demog…
View article: Gender-Specific Differences in Human Vertebral Bone Marrow Clot
Gender-Specific Differences in Human Vertebral Bone Marrow Clot Open
Recently, our group described the application of vertebral bone marrow (vBMA) clot as a cell therapy strategy for spinal fusion. Its beneficial effects were confirmed in aging-associated processes, but the influence of gender is unknown. I…
View article: Carbon Fiber-Reinforced PolyEtherEtherKetone (CFR-PEEK) Instrumentation in Degenerative Disease of Lumbar Spine: A Pilot Study
Carbon Fiber-Reinforced PolyEtherEtherKetone (CFR-PEEK) Instrumentation in Degenerative Disease of Lumbar Spine: A Pilot Study Open
CFR-PEEK is gaining popularity in spinal oncological applications due to its reduction of imaging artifacts and radiation scattering compared with titanium, which allows for better oncological follow-up and efficacy of radiotherapy. We eva…
View article: Indications and Limits of Surgery for Spinal Metastases Derived from Lung Cancer: A Single-Center Experience
Indications and Limits of Surgery for Spinal Metastases Derived from Lung Cancer: A Single-Center Experience Open
Lung cancer is the second most frequently diagnosed cancer in the world, and surgery is an integral part of the treatment for spinal metastases. The aims of this retrospective study were to assess the overall survival of surgically treated…
View article: Does the choice of chemoprophylaxis affect the prevention of deep vein thrombosis in lumbar fusion surgery? A systematic review of the literature
Does the choice of chemoprophylaxis affect the prevention of deep vein thrombosis in lumbar fusion surgery? A systematic review of the literature Open
Both LMWH and UH reduces the overall incidence of DVT/PE, but there is a paucity of evidence analyzing the comparative effectiveness of the chemoprophylaxis regimens in lumbar fusion procedures. The heterogeneity in data prevents any concl…
View article: Ceramic bone graft substitute (Mg-HA) in spinal fusion: A prospective pilot study
Ceramic bone graft substitute (Mg-HA) in spinal fusion: A prospective pilot study Open
Background: Iliac crest bone graft (ICBG) is considered the gold standard for spine surgical procedures to achieve a successful fusion due to its known osteoinductive and osteoconductive properties. However, complications related to harves…
View article: Complications in Spinal Fusion Surgery: A Systematic Review of Clinically Used Cages
Complications in Spinal Fusion Surgery: A Systematic Review of Clinically Used Cages Open
Spinal fusion (SF) comprises surgical procedures for several pathologies that affect different spinal levels, and different cages are employed in SF surgery. Few clinical studies highlight the role of cages in complications beyond the outc…
View article: Complications and Risk Factors in En Bloc Resection of Spinal Tumors: A Retrospective Analysis on 298 Patients Treated in a Single Institution
Complications and Risk Factors in En Bloc Resection of Spinal Tumors: A Retrospective Analysis on 298 Patients Treated in a Single Institution Open
En bloc resection consists in the surgical removal of a vertebral tumor in a single piece with a sufficient margin, to improve survival and reduce recurrence rate. This procedure is technically demanding and correlates with a high complica…
View article: Custom-Made 3D-Printed Implants for Anterior Column Reconstruction in the Upper Cervical Spine after Intralesional Extracapsular Excision—Report of 2 Cases and Literature Review
Custom-Made 3D-Printed Implants for Anterior Column Reconstruction in the Upper Cervical Spine after Intralesional Extracapsular Excision—Report of 2 Cases and Literature Review Open
The use of three-dimensional (3D)-printed custom-made implants is spreading in the orthopedics field for the reconstruction of bone losses or for joint replacement, thanks to their unparalleled versatility. In particular, this novel techno…
View article: A Novel Quantitative Computer-Assisted Score Can Improve Repeatability in the Estimate of Vascular Calcifications at the Abdominal Aorta
A Novel Quantitative Computer-Assisted Score Can Improve Repeatability in the Estimate of Vascular Calcifications at the Abdominal Aorta Open
In CKD and in the elderly, Vascular Calcifications (VC) are associated to cardiovascular events and bone fractures. VC scores at the abdominal aorta (AA) from lateral spine radiographs are widely applied (the 0–24 semiquantitative discrete…
View article: Clear Cell Renal Cell Carcinoma Spinal Metastases: Which Factors Matter to the Overall Survival? A 10-Year Experience of a High-Volume Tumor Spine Center
Clear Cell Renal Cell Carcinoma Spinal Metastases: Which Factors Matter to the Overall Survival? A 10-Year Experience of a High-Volume Tumor Spine Center Open
Clear cell renal cell carcinoma (ccRCC) usually spreads in the spinal region causing instability or spinal cord compression leading to neurological deficits. Therefore, surgical treatment is required for improving the outcome of patients. …