Giovanni Gabutti
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View article: Vaccinations Included in the National Immunization Calendar as a Tool to Tackle Antimicrobial Resistance: Current Evidence for Selected Pathogens in Italy
Vaccinations Included in the National Immunization Calendar as a Tool to Tackle Antimicrobial Resistance: Current Evidence for Selected Pathogens in Italy Open
Background/Objectives: Antimicrobial (AMR) and antibiotic resistance (AR) remain major growing issues around the world. According to WHO, vaccinations play a strategic role in tackling AMR/AR; the new (upcoming) or existing vaccines (both …
View article: Timely Prevention of Adolescent Invasive Meningococcal Disease
Timely Prevention of Adolescent Invasive Meningococcal Disease Open
In August 2025, EMJ conducted individual interviews with two European medical experts and a patient advocate who had survived infection in adolescence on the critical importance of timely immunisation against invasive meningococcal disease…
View article: Breaking the cycle: considerations for a life-course vaccination strategy against varicella-zoster virus
Breaking the cycle: considerations for a life-course vaccination strategy against varicella-zoster virus Open
Varicella and HZ pose significant burdens. The availability of effective vaccines with established safety profiles means that prevention of both manifestations of VZV disease is now largely possible. Reasons why National Immunization Techn…
View article: Overview of adult immunization in Italy: Successes, lessons learned and the way forward
Overview of adult immunization in Italy: Successes, lessons learned and the way forward Open
The exchange of knowledge and best practices in adult immunization are essential to improve vaccination strategies across the European region. Italy has made groundbreaking progress in the field, being one of the first countries to propose…
View article: Pertussis Notification Rate and Tdpa Vaccine/Booster Coverage in Adults: An Opportunity for an Epidemiological Observatory in Primary Care
Pertussis Notification Rate and Tdpa Vaccine/Booster Coverage in Adults: An Opportunity for an Epidemiological Observatory in Primary Care Open
Background: In recent years, Europe has experienced a significant increase in pertussis cases. One reason behind this rise is the decline in diphtheria–tetanus–pertussis (dTap) booster coverage among adults. Currently, Italy lacks a reliab…
View article: Mapping and ranking outcomes for the evaluation of seasonal influenza vaccine efficacy and effectiveness: a delphi study
Mapping and ranking outcomes for the evaluation of seasonal influenza vaccine efficacy and effectiveness: a delphi study Open
Rather than focusing on laboratory-confirmed infection per se, experimental and observational VE studies should include more severe influenza-related outcomes because they are expected to exercise a greater impact on decision-making.
View article: Seroprevalence of measles antibodies in the Italian general population in 2019–2020
Seroprevalence of measles antibodies in the Italian general population in 2019–2020 Open
View article: Seroprotection against tetanus in the Italian general population
Seroprotection against tetanus in the Italian general population Open
These data, compared with epidemiological ones which showed a high number of cases in the elderly, confirmed that the population with lower protection has a greater risk of contracting the disease, demonstrating the need for adequate immun…
View article: Diabetes as a risk factor for pneumococcal disease and severe related outcomes and efficacy/effectiveness of vaccination in diabetic population. Results from meta-analysis of observational studies
Diabetes as a risk factor for pneumococcal disease and severe related outcomes and efficacy/effectiveness of vaccination in diabetic population. Results from meta-analysis of observational studies Open
View article: Available evidence on the co-administration of the four-component meningococcal B vaccine (4CMenB) with three vaccines at the same visit among pediatric individuals
Available evidence on the co-administration of the four-component meningococcal B vaccine (4CMenB) with three vaccines at the same visit among pediatric individuals Open
Vaccine co-administration is a useful strategy for improving vaccine coverage and adherence. In Italy, an update to the national immunization program (NIP) in 2023 included recommendations for co-administration of pediatric vaccines, inclu…
View article: History of Human Papilloma Virus Vaccination with a Focus on Italy
History of Human Papilloma Virus Vaccination with a Focus on Italy Open
The Italian National Immunization Plan (NIP) states that public health today aims at immunizing adolescents of both sexes for maximum protection against all HPV-related vaccine-preventable diseases. Nowadays, the vaccination offer to prima…
View article: Artificial Intelligence and Public Health: Evaluating ChatGPT Responses to Vaccination Myths and Misconceptions
Artificial Intelligence and Public Health: Evaluating ChatGPT Responses to Vaccination Myths and Misconceptions Open
Artificial intelligence (AI) tools, such as ChatGPT, are the subject of intense debate regarding their possible applications in contexts such as health care. This study evaluates the Correctness, Clarity, and Exhaustiveness of the answers …
View article: Efficacy and effectiveness of Herpes zoster vaccination in adults with diabetes mellitus: a systematic review and meta-analysis of clinical trials and observational studies
Efficacy and effectiveness of Herpes zoster vaccination in adults with diabetes mellitus: a systematic review and meta-analysis of clinical trials and observational studies Open
View article: Influenza: Diabetes as a risk factor for severe related-outcomes and the effectiveness of vaccination in diabetic population. A meta-analysis of observational studies
Influenza: Diabetes as a risk factor for severe related-outcomes and the effectiveness of vaccination in diabetic population. A meta-analysis of observational studies Open
View article: The future for COVID-19 vaccines: public health assessment and perspectives based on scientific evidence
The future for COVID-19 vaccines: public health assessment and perspectives based on scientific evidence Open
The development and use of messenger RNA-based (mRNA) vaccines against the SARS-CoV-2 spike protein have proven to be highly effective against symptomatic COVID-19, especially for severe forms. Since the declaration of a public health emer…
View article: Assessment of Pertussis Underreporting in Italy
Assessment of Pertussis Underreporting in Italy Open
A study was conducted to assess the degree of pertussis underreporting in Italy. An analysis was performed to compare the frequency of pertussis infections estimated using seroprevalence data with the pertussis incidence based on reported …
View article: Sero-Epidemiological Study of Varicella in the Italian General Population
Sero-Epidemiological Study of Varicella in the Italian General Population Open
The aim of this study was to analyze the seroprevalence of varicella in Italy and to evaluate the impact of varicella vaccination, which has been mandatory for newborns since 2017. The levels of VZV-specific IgG antibodies were determined …
View article: Sero-Epidemiological Study of Bordetella pertussis Infection in the Italian General Population
Sero-Epidemiological Study of Bordetella pertussis Infection in the Italian General Population Open
A multicenter study was conducted to estimate the prevalence of pertussis IgG antibodies (anti-PTx) in the Italian population. Serum samples (4154) collected in the years 2019–2020 from subjects aged 6 to 90 years were tested. The anti-PTx…
View article: Available evidence and potential for vaccines for reduction in antibiotic prescriptions
Available evidence and potential for vaccines for reduction in antibiotic prescriptions Open
Bacterial antibiotic resistance is a public health issue. It means that drugs become ineffective, infections persist and have a huge impact on the health of patients and their spreading increases. To address a complex threat such as bacter…
View article: Experts’ Opinion for Improving Pertussis Vaccination Rates in Adolescents and Adults: A Call to Action
Experts’ Opinion for Improving Pertussis Vaccination Rates in Adolescents and Adults: A Call to Action Open
This article highlights the importance of diphtheria-tetanus-acellular pertussis (with reduced antigen content, dTap) vaccination in preventing pertussis, a respiratory infection that is still widespread and easily transmitted. In particul…
View article: Improving vaccination rates in older adults and at-risk groups: focus on pertussis
Improving vaccination rates in older adults and at-risk groups: focus on pertussis Open
View article: Human Papilloma Virus Vaccination: Focus on the Italian Situation
Human Papilloma Virus Vaccination: Focus on the Italian Situation Open
Human papilloma virus (HPV) is a viral agent whose transmission occurs mainly by sexual means. It causes different pathological conditions in both males and females, ranging from benign pathologies up to cancers. The introduction of vaccin…
View article: Manifesto on the Value of Adult Immunization: “We Know, We Intend, We Advocate”
Manifesto on the Value of Adult Immunization: “We Know, We Intend, We Advocate” Open
Immunization through vaccination is a milestone achievement that has made a tremendous contribution to public health. Historically, immunization programs aimed firstly to protect children, who were disproportionally affected by infectious …
View article: How has COVID-19 pandemic changed flu vaccination attitudes among an Italian cancer center healthcare workers?
How has COVID-19 pandemic changed flu vaccination attitudes among an Italian cancer center healthcare workers? Open
A retrospective study was conducted among Italian cancer healthcare workers (HCWs) to describe how influenza vaccination attitudes have changed during the COVID-19 pandemic. The analysis was conducted on the last three influenza seasons (2…
View article: Fourteen years’ clinical experience and the first million babies protected with human live-attenuated vaccine against rotavirus disease in Italy
Fourteen years’ clinical experience and the first million babies protected with human live-attenuated vaccine against rotavirus disease in Italy Open
Rotavirus (RV) causes up to half of hospital and community acute gastroenteritis (AGE) cases in young children in Italy. Two RV vaccines, available since 2006, are human RV (HRV) and human bovine RV (HBRV). This report looks back at the im…
View article: The Epidemiological Characteristics of the COVID-19 Pandemic in Europe: Focus on Italy
The Epidemiological Characteristics of the COVID-19 Pandemic in Europe: Focus on Italy Open
Starting from December 2019, SARS-CoV-2 has forcefully entered our lives and profoundly changed all the habits of the world population. The COVID-19 pandemic has violently impacted the European continent, first involving only some European…
View article: Value of Immunizations during the COVID-19 Emergency
Value of Immunizations during the COVID-19 Emergency Open
Recent estimates by World Health Organization (WHO, Geneva, Switzerland) and United Nations International Children’s Emergency Fund (UNICEF) show a significant decline in vaccinal coverage rates in both pediatric and adult populations. The…
View article: Attitudes and Beliefs on Influenza Vaccination during the COVID-19 Pandemic: Results from a Representative Italian Survey
Attitudes and Beliefs on Influenza Vaccination during the COVID-19 Pandemic: Results from a Representative Italian Survey Open
The last 2019/20 northern hemisphere influenza season overlapped with the first wave of coronavirus disease 2019 (COVID-19) pandemic. Italy was the first western country where severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sp…
View article: Evaluation and review of preventive measures applied during COVID-19 pandemic: strategies adopted by European countries
Evaluation and review of preventive measures applied during COVID-19 pandemic: strategies adopted by European countries Open
The COVID-19 pandemic has greatly jeopardized the European continent and the spread of SARS-COV-2 has led European countries to implement a series of preventive interventions aimed at decreasing the incidence rate of the disease, in consid…