Girish Thunga
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View article: Development and evaluation of a diagnostic aiding tool for differentiating tropical fevers using artificial intelligence approach: a study protocol from tertiary care hospital in South India
Development and evaluation of a diagnostic aiding tool for differentiating tropical fevers using artificial intelligence approach: a study protocol from tertiary care hospital in South India Open
Introduction Application of artificial intelligence (AI) tools in the healthcare setting gains importance especially in the domain of disease diagnosis. Numerous studies have tried to explore AI in the diagnosis of various diseases, includ…
View article: P04 Low-dose polymyxin B is non-inferior to conventional doses in dialysis dependent and non-dialysis patients with Gram-negative sepsis: a real-world propensity-score matched cohort study
P04 Low-dose polymyxin B is non-inferior to conventional doses in dialysis dependent and non-dialysis patients with Gram-negative sepsis: a real-world propensity-score matched cohort study Open
Background Polymyxin B remains a key treatment option for infections caused by MDR Gram-negative bacilli, particularly in critically ill patients. However, its optimal dosing strategy recommendation remains uncertain, especially in those u…
View article: Knowledge, Attitudes, and Practices Regarding Nutrition and Worm Infestation Among Parents/Guardians of Tribal Children of Udupi District: A Cross-Sectional Assessment
Knowledge, Attitudes, and Practices Regarding Nutrition and Worm Infestation Among Parents/Guardians of Tribal Children of Udupi District: A Cross-Sectional Assessment Open
Background The Koraga tribe, a particularly vulnerable tribal group (PVTG) in India, faces significant health disparities, especially among children. This study focussed on assessing knowledge, attitude, and practices (KAP) regarding nutri…
View article: Machine-learning-based artificial intelligence tools for the diagnosis of tropical fevers: a systematic review and meta-analysis protocol of diagnostic test accuracy
Machine-learning-based artificial intelligence tools for the diagnosis of tropical fevers: a systematic review and meta-analysis protocol of diagnostic test accuracy Open
Introduction Recent advancements in diagnosing tropical fevers increasingly use artificial intelligence (AI). These innovations focus on diagnosing single or multiple diseases, significantly reducing the global burden of tropical fevers. T…
View article: Vitamin D status and its association with diabetic complications in type 2 diabetes mellitus: A case-control study
Vitamin D status and its association with diabetic complications in type 2 diabetes mellitus: A case-control study Open
Background: Vitamin D deficiency remains as a significant public health challenge, even in sun-rich countries like India. Emerging evidence indicates that vitamin D plays a critical role in the pathophysiology of various chronic conditions…
View article: CSF biomarkers in leak detection: A systematic review & meta-analysis of diagnostic test accuracy (DTA) studies
CSF biomarkers in leak detection: A systematic review & meta-analysis of diagnostic test accuracy (DTA) studies Open
CSF biomarkers show high diagnostic accuracy, offering a promising alternative to neuroimaging. Standardizing biomarker thresholds and assay methodologies are crucial for reliability. Further research should address confounding factors and…
View article: Development, validation, and reliability of a questionnaire to assess risk-factors of chronic kidney disease of unknown etiology
Development, validation, and reliability of a questionnaire to assess risk-factors of chronic kidney disease of unknown etiology Open
Background Chronic Kidney Disease of unknown aetiology (CKDu) is an emerging global health issue, yet research on risk factors is limited. This study addresses the gap by developing, validating, and evaluating the reliability of a question…
View article: Role of vitamin D in the development and progression of diabetic kidney disease: an overview of meta-analyses
Role of vitamin D in the development and progression of diabetic kidney disease: an overview of meta-analyses Open
Background: The effectiveness of vitamin D supplementation in the progression of diabetic kidney disease (DKD) remains controversial. Our review tries to provide a comprehensive summary of all the relevant articles in the area to assess th…
View article: Identification of Common Bacterial Pathogens Causing Skin Lesions and Their Antibiotic Susceptibility Patterns in Children and Adults in the Indian Subcontinent: A Scoping Review Protocol
Identification of Common Bacterial Pathogens Causing Skin Lesions and Their Antibiotic Susceptibility Patterns in Children and Adults in the Indian Subcontinent: A Scoping Review Protocol Open
Background Skin and Soft tissue infections (SSTIs) have become a global public health threat especially in the Indian context. Secondary complications from untreated skin lesions makes the patient life miserable and results in serious adve…
View article: Machine Learning in Predicting Child Malnutrition: A Meta-Analysis of Demographic and Health Surveys Data
Machine Learning in Predicting Child Malnutrition: A Meta-Analysis of Demographic and Health Surveys Data Open
Background: Childhood malnutrition remains a significant global public health concern. The Demographic and Health Surveys (DHS) program provides specific data on child health across numerous countries. This meta-analysis aims to comprehens…
View article: Effect of video-assisted educational intervention on improving knowledge, attitude and practice among mothers of children below five years on malnutrition: A systematic review
Effect of video-assisted educational intervention on improving knowledge, attitude and practice among mothers of children below five years on malnutrition: A systematic review Open
Video-assisted educational interventions were effective in KAP concerning feeding practices among mothers of children aged <5 years. However, their impact on children's z-scores remain inconclusive, emphasising the need for further researc…
View article: Consumers’ and practitioners’ perspectives on the antipsychotic induced metabolic syndrome and challenges in metabolic monitoring to patient prescribed second generation antipsychotics in severe mental illness
Consumers’ and practitioners’ perspectives on the antipsychotic induced metabolic syndrome and challenges in metabolic monitoring to patient prescribed second generation antipsychotics in severe mental illness Open
Second-generation antipsychotics are highly effective in controlling symptoms if taken as prescribed. However, poor medication adherence results in patients continuing to experience psychotic episodes and metabolic disturbances that can ca…
View article: Role of C5aR2 in prognosis of patients with acute respiratory distress syndrome through negative modulation of C5a: A prospective observational study
Role of C5aR2 in prognosis of patients with acute respiratory distress syndrome through negative modulation of C5a: A prospective observational study Open
The current evidence indicates that a higher levels of C5aR2 significantly associated with better recovery, whereas high levels of C5a/C5aR2 significantly associated to poor prognosis in moderate to severe ARDS patients. However, adequatel…
View article: Impact of Home Medicines Review on medication regimen complexity
Impact of Home Medicines Review on medication regimen complexity Open
Background Previous studies on pharmacist‐led Home Medicines Review (HMR) have demonstrated positive associations of HMR and clinical outcomes. However, little is known about their impact on medication regimen complexity. Aim Investigate t…
View article: Effect of chronic kidney disease on adverse drug reactions to anti-tubercular treatment: a retrospective cohort study
Effect of chronic kidney disease on adverse drug reactions to anti-tubercular treatment: a retrospective cohort study Open
ATT-associated ADRs were more common and severe in patients with CKD, despite drug dose modifications. Optimal dosing of ATT in CKD needs to be further evaluated.
View article: Development of a machine learning-based model for the prediction and progression of diabetic kidney disease: A single centred retrospective study
Development of a machine learning-based model for the prediction and progression of diabetic kidney disease: A single centred retrospective study Open
Machine learning algorithms can effectively predict the stages of DKD and thus help physicians in providing patients with personalized care at the right time.
View article: Vaccine-associated paralytic poliomyelitis in oral polio vaccine recipients: disproportionality analysis using VAERS and systematic review
Vaccine-associated paralytic poliomyelitis in oral polio vaccine recipients: disproportionality analysis using VAERS and systematic review Open
The study emphasized the seriousness of VAPP and highlights its association with OPV, identifying immunodeficiency as a prominent contributor to VAPP manifestation.
View article: #329 Effectiveness of dosing strategies of polymyxin B among sepsis patients with and without renal replacement therapies
#329 Effectiveness of dosing strategies of polymyxin B among sepsis patients with and without renal replacement therapies Open
Background and Aims Despite numerous population pharmacokinetic studies on polymyxin B, a gap exists in establishing uniform dosing strategies among sepsis patients due to various clinical and patient related factors. The International Con…
View article: WCN24-2236 COMPARISON OF FIRST-LINE ANTI-TUBERCULAR DRUGS LEVELS IN TUBERCULOSIS (TB) WITH AND WITHOUT CHRONIC KIDNEY DISEASE (CKD)
WCN24-2236 COMPARISON OF FIRST-LINE ANTI-TUBERCULAR DRUGS LEVELS IN TUBERCULOSIS (TB) WITH AND WITHOUT CHRONIC KIDNEY DISEASE (CKD) Open
Chronic kidney disease (CKD) has an increased risk of contracting tuberculosis (TB), with an incidence rate of 3,718 cases per 100,000 CKD patients. Standard four drugs (isoniazid, rifampin, pyrazinamide, and ethambutol) treatment are asso…
View article: Factors associated with dietary and exercise compliance among elderly with chronic conditions of hypertension and type 2 diabetes mellitus residing in rural areas of coastal Karnataka: A community-based cross-sectional study
Factors associated with dietary and exercise compliance among elderly with chronic conditions of hypertension and type 2 diabetes mellitus residing in rural areas of coastal Karnataka: A community-based cross-sectional study Open
BACKGROUND: Compliance with diet, exercise regimen, and medication is vital to maintain an acceptable range of blood pressure and glycemic level among elderly with hypertension and diabetes mellitus. However, these are considered to be mor…
View article: Clinical characteristics, management, outcome, and cost of stings and bites in patients admitted to a tertiary care teaching hospital
Clinical characteristics, management, outcome, and cost of stings and bites in patients admitted to a tertiary care teaching hospital Open
Aim: The objective of this study was to identify the clinical epidemiology and medical cost of stings and bites at a tertiary care hospital in South India. Subjects and Methods: The medical records of hospitalized patients in the tertiary …