Giselle Mosnaim
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View article: EFFICACY OF REMIBRUTINIB IN ANTI-IGE BIOLOGIC-NAÏVE, BIOLOGIC-EXPERIENCED, AND BIOLOGIC-REFRACTORY PATIENTS WITH CSU: REMIX-1/-2 STUDIES
EFFICACY OF REMIBRUTINIB IN ANTI-IGE BIOLOGIC-NAÏVE, BIOLOGIC-EXPERIENCED, AND BIOLOGIC-REFRACTORY PATIENTS WITH CSU: REMIX-1/-2 STUDIES Open
View article: Specialist care improves diagnosis and treatment for patients with chronic spontaneous urticaria: A real-world survey
Specialist care improves diagnosis and treatment for patients with chronic spontaneous urticaria: A real-world survey Open
View article: Remibrutinib in chronic spontaneous urticaria: 52-week results from two phase 3 studies
Remibrutinib in chronic spontaneous urticaria: 52-week results from two phase 3 studies Open
Remibrutinib showed sustained efficacy and a consistent, favorable long-term safety profile in patients with CSU remaining symptomatic despite second-generation H1-antihistamines.
View article: CO143 Outcomes In Patients With Asthma and Coexisting Allergic Rhinitis Who Started Dupilumab Treatment In Real-World Clinical Practice: A RAPID Registry Study
CO143 Outcomes In Patients With Asthma and Coexisting Allergic Rhinitis Who Started Dupilumab Treatment In Real-World Clinical Practice: A RAPID Registry Study Open
View article: How accurate are ChatGPT-4 responses in chronic urticaria? A critical analysis with information quality metrics
How accurate are ChatGPT-4 responses in chronic urticaria? A critical analysis with information quality metrics Open
View article: Triple therapy vs dual inhaler therapy for moderate-to-severe asthma
Triple therapy vs dual inhaler therapy for moderate-to-severe asthma Open
View article: Remote monitoring in asthma: a systematic review
Remote monitoring in asthma: a systematic review Open
Background Poor adherence to maintenance inhalers and incorrect maintenance and reliever inhaler technique are associated with poor asthma outcomes. Remote therapeutic monitoring and remote patient monitoring support asthma guideline recom…
View article: Inhaled Reliever Therapies for Asthma
Inhaled Reliever Therapies for Asthma Open
Importance The optimal inhaled reliever therapy for asthma remains unclear. Objective To compare short-acting β agonists (SABA) alone with SABA combined with inhaled corticosteroids (ICS) and with the fast-onset, long-acting β agonist form…
View article: Case report of an unusual allergic reaction to a routine skin prick test performed in an outpatient clinic: Diagnosis, management, and knowledge gaps
Case report of an unusual allergic reaction to a routine skin prick test performed in an outpatient clinic: Diagnosis, management, and knowledge gaps Open
Background: The skin prick test (SPT) is a standard procedure in allergy/immunology clinics, crucial for evaluating conditions like allergic rhinitis and food allergies. As a cornerstone in investigating immunoglobulin E-mediated allergy, …
View article: Trial Characteristics of Randomized Controlled Trials Evaluating Bronchial Thermoplasty in Moderate and Severe Asthma: An AAAAI/ACAAI JTFPP Systematic Review
Trial Characteristics of Randomized Controlled Trials Evaluating Bronchial Thermoplasty in Moderate and Severe Asthma: An AAAAI/ACAAI JTFPP Systematic Review Open
View article: Factors associated with chronic spontaneous urticaria diagnostic and treatment delay in real-world clinical practice
Factors associated with chronic spontaneous urticaria diagnostic and treatment delay in real-world clinical practice Open
View article: An AAAAI/ACAAI Joint Task Force on Practice Parameters Updated Systematic Review of Triple vs Dual Inhaler Therapy and Asthma Outcomes in Moderate to Severe Asthma
An AAAAI/ACAAI Joint Task Force on Practice Parameters Updated Systematic Review of Triple vs Dual Inhaler Therapy and Asthma Outcomes in Moderate to Severe Asthma Open
View article: Efficacy of Remibrutinib in Patients With Chronic Spontaneous Urticaria With or Without Prior Exposure to Biologics in the Phase 3 REMIX-1 and REMIX-2 Studies
Efficacy of Remibrutinib in Patients With Chronic Spontaneous Urticaria With or Without Prior Exposure to Biologics in the Phase 3 REMIX-1 and REMIX-2 Studies Open
View article: Creating a plasma coordination center to support COVID-19 outpatient trials across a national network of hospital blood banks
Creating a plasma coordination center to support COVID-19 outpatient trials across a national network of hospital blood banks Open
Introduction: In response to the COVID-19 pandemic, we rapidly implemented a plasma coordination center, within two months, to support transfusion for two outpatient randomized controlled trials. The center design was based on an investiga…
View article: Erratum for Gebo et al., “Early antibody treatment, inflammation, and risk of post-COVID conditions”
Erratum for Gebo et al., “Early antibody treatment, inflammation, and risk of post-COVID conditions” Open
Volume 14, no. 5, e00618-23, 2023, https://journals.asm.org/doi/10.1128/mbio.00618-23. Page 6, Table 1, last row: "3,041 (2,197, 4,208)" should read "13,774 (8,665, 21,896)," and "13,774 (8,665, 21,896)" should read "3,041 (2,197, 4,208)."
View article: Effectiveness of a Maintenance and Reliever Digihaler System in Asthma: 24-Week Randomized Study (CONNECT2)
Effectiveness of a Maintenance and Reliever Digihaler System in Asthma: 24-Week Randomized Study (CONNECT2) Open
The positive results in asthma control in this study after 24 weeks demonstrate the effectiveness of the DS in asthma management.
View article: 401. Risk of Post-COVID Conditions Correlates with IL-6 Plasma Levels and Is Reduced by Early Antibody Therapy
401. Risk of Post-COVID Conditions Correlates with IL-6 Plasma Levels and Is Reduced by Early Antibody Therapy Open
Background Post-COVID conditions (PCC) are common, and risk factors include older age and female sex. While high interleukin (IL)-6 and C-reactive protein are associated with more severe disease, it is unclear whether other cytokines are a…
View article: DIGIHALER SYSTEM USE BY HEALTHCARE PROFESSIONALS AND APP CONNECTIVITY IN ASTHMA PATIENTS: A PRAGMATIC STUDY
DIGIHALER SYSTEM USE BY HEALTHCARE PROFESSIONALS AND APP CONNECTIVITY IN ASTHMA PATIENTS: A PRAGMATIC STUDY Open
View article: M15 Quantification of clinical deterioration of asthma based on threshold for SABA use in two studies of the digihaler system
M15 Quantification of clinical deterioration of asthma based on threshold for SABA use in two studies of the digihaler system Open
Background In two studies of the Digihaler System (DS), patients with suboptimally controlled asthma used an albuterol inhaler with an integrated sensor that objectively recorded real-time reliever use. US asthma experts, through a modifie…
View article: M16 Recognizing asthma risk scenarios: individualized inhaler usage and inhalation parameter profiles from an electronic inhaler with integrated sensors
M16 Recognizing asthma risk scenarios: individualized inhaler usage and inhalation parameter profiles from an electronic inhaler with integrated sensors Open
Rationale Suboptimal adherence, errors in inhaler technique, and reliever overuse are risk factors associated with poor asthma outcomes. The Digihaler® electronic inhaler provides objective data on usage and inhalation parameter…
View article: Dynamics of inflammatory responses after SARS-CoV-2 infection by vaccination status in the USA: a prospective cohort study
Dynamics of inflammatory responses after SARS-CoV-2 infection by vaccination status in the USA: a prospective cohort study Open
View article: Preference for and impact of telehealth vs in-person asthma visits among Black and Latinx adults
Preference for and impact of telehealth vs in-person asthma visits among Black and Latinx adults Open
View article: Outpatient COVID-19 convalescent plasma recipient antibody thresholds correlated to reduced hospitalizations within a randomized trial
Outpatient COVID-19 convalescent plasma recipient antibody thresholds correlated to reduced hospitalizations within a randomized trial Open
BACKGROUND The COVID-19 convalescent plasma (CCP) viral specific antibody levels that translate into recipient post-transfusion antibody levels sufficient to prevent disease progression is not defined. METHODS This secondary analysis corre…
View article: Early Treatment, Inflammation and Post-COVID Conditions
Early Treatment, Inflammation and Post-COVID Conditions Open
Background Post-COVID conditions (PCC) are common and have significant morbidity. Risk factors for PCC include advancing age, female sex, obesity, and diabetes mellitus. Little is known about early treatment, inflammation, and PCC. Methods…
View article: Use of Theory-Based Implementation Research to Evaluate Barriers and Facilitators to Implementation of a Novel Digital Inhaler Technology in Clinical Practice
Use of Theory-Based Implementation Research to Evaluate Barriers and Facilitators to Implementation of a Novel Digital Inhaler Technology in Clinical Practice Open
View article: Implementation of a Novel Digital Inhaler Technology in Real-World Clinical Practice: Experiences and Recommendations from Early Adopters
Implementation of a Novel Digital Inhaler Technology in Real-World Clinical Practice: Experiences and Recommendations from Early Adopters Open
View article: Symptom Duration and Resolution With Early Outpatient Treatment of Convalescent Plasma for Coronavirus Disease 2019: A Randomized Trial
Symptom Duration and Resolution With Early Outpatient Treatment of Convalescent Plasma for Coronavirus Disease 2019: A Randomized Trial Open
Background Coronavirus disease 2019 (COVID-19) convalescent plasma (CCP) reduces hospitalizations among outpatients treated early after symptom onset. It is unknown whether CCP reduces time to symptom resolution among outpatients. Methods …
View article: Integrating digital inhalers into clinical care of patients with asthma and chronic obstructive pulmonary disease
Integrating digital inhalers into clinical care of patients with asthma and chronic obstructive pulmonary disease Open
View article: Effectiveness of a Digital Inhaler System for Patients With Asthma: A 12-Week, Open-Label, Randomized Study (CONNECT1)
Effectiveness of a Digital Inhaler System for Patients With Asthma: A 12-Week, Open-Label, Randomized Study (CONNECT1) Open
In this study, participants using the RDS had greater odds of clinically meaningful improvements in asthma control versus SoC after 3 months. Further investigation of the potential of the RDS to help improve asthma management is warranted.
View article: Randomized Controlled Trial of Early Outpatient COVID-19 Treatment with High-Titer Convalescent Plasma
Randomized Controlled Trial of Early Outpatient COVID-19 Treatment with High-Titer Convalescent Plasma Open
BACKGROUND The efficacy of polyclonal high titer convalescent plasma to prevent serious complications of COVID-19 in outpatients with recent onset of illness is uncertain. METHODS This multicenter, double-blind randomized controlled trial …