Giulia Di Rocco
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View article: The effect of ionic strength on PETase enzymes: an experimental and computational study
The effect of ionic strength on PETase enzymes: an experimental and computational study Open
In the last decades, several enzymes capable of hydrolyzing polyethylene terephthalate (PET) under different conditions have been discovered, offering innovative and sustainable solutions for managing plastic waste in the ecosystems. The P…
View article: Functional and Structural Characterization of PETase SM14 from Marine-Sponge <i>Streptomyces</i> sp. Active on Polyethylene Terephthalate
Functional and Structural Characterization of PETase SM14 from Marine-Sponge <i>Streptomyces</i> sp. Active on Polyethylene Terephthalate Open
The recent discovery of the PETase enzyme family offers a sustainable solution for depolymerizing poly-(ethylene terephthalate) (PET), one of the most widespread plastic compounds, under mild conditions. This enables the environmentally be…
View article: Electrochemical and Spectroscopic Characterization of Co-Neuroglobin: A Bioelectrocatalyst for H<sub>2</sub> Production
Electrochemical and Spectroscopic Characterization of Co-Neuroglobin: A Bioelectrocatalyst for H<sub>2</sub> Production Open
The electronic absorption, MCD, and RR spectra of the Co(III) and Co(II) derivatives of wild-type human neuroglobin (Co-WT) and its C46A/C55A mutant (Co-C46AC55A) were thoroughly investigated and compared with those of the corresponding Fe…
View article: Efficient Electrocatalytic H<sub>2</sub> Production by Immobilized Co(III)‐myoglobin
Efficient Electrocatalytic H<sub>2</sub> Production by Immobilized Co(III)‐myoglobin Open
The thermodynamics and kinetics of heterogeneous electron transfer (ET) for Co‐substituted horse myoglobin (Co−Mb) and its derivatives with ammonia and imidazole as heme axial ligands were studied with cyclic voltammetry on a pyrolytic gra…
View article: Effects of removal of the axial methionine heme ligand on the binding of S. cerevisiae iso-1 cytochrome c to cardiolipin
Effects of removal of the axial methionine heme ligand on the binding of S. cerevisiae iso-1 cytochrome c to cardiolipin Open
View article: A PETase enzyme synthesised in the chloroplast of the microalga Chlamydomonas reinhardtii is active against post-consumer plastics
A PETase enzyme synthesised in the chloroplast of the microalga Chlamydomonas reinhardtii is active against post-consumer plastics Open
View article: BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting Open
The management of advanced-stage melanoma is clinically challenging, mainly because of its resistance to the currently available therapies. Therefore, it is important to develop alternative therapeutic strategies. The sigma-2 receptor (S2R…
View article: A PETase enzyme synthesised in the chloroplast of the microalga Chlamydomonas reinhardtii is active against PET and polystyrene
A PETase enzyme synthesised in the chloroplast of the microalga Chlamydomonas reinhardtii is active against PET and polystyrene Open
Polyethylene terephthalate hydrolases (PETases) are a newly discovered and industrially important class of enzymes that catalyze the enzymatic degradation of polyethylene terephatalate (PET), one of the most abundant plastics in the world.…
View article: A PETase enzyme synthesised in the chloroplast of the microalga Chlamydomonas reinhardtii is active against PET and polystyrene
A PETase enzyme synthesised in the chloroplast of the microalga Chlamydomonas reinhardtii is active against PET and polystyrene Open
The list contains: 1) raw data for chromatographies: HiprepSPHP and SEC 2) raw data for UV-vis Spectrum 3) raw data for all MS/MS spectra manuscript + supplementary 4) raw data for AFM 5) report data from HPLC
View article: A PETase enzyme synthesised in the chloroplast of the microalga Chlamydomonas reinhardtii is active against PET and polystyrene
A PETase enzyme synthesised in the chloroplast of the microalga Chlamydomonas reinhardtii is active against PET and polystyrene Open
The list contains: 1) raw data for chromatographies: HiprepSPHP and SEC 2) raw data for UV-vis Spectrum 3) raw data for all MS/MS spectra manuscript + supplementary 4) raw data for AFM
View article: A PETase enzyme synthesised in the chloroplast of the microalga Chlamydomonas reinhardtii is active against PET and polystyrene
A PETase enzyme synthesised in the chloroplast of the microalga Chlamydomonas reinhardtii is active against PET and polystyrene Open
The list contains: 1) raw data for chromatographies: HiprepSPHP and SEC 2) raw data for UV-vis Spectrum 3) raw data for all MS/MS spectra manuscript + supplementary 4) raw data for AFM 5) report data from HPLC
View article: Thermodynamics and Kinetics of Electron Transfer of Electrode-Immobilized Small Laccase from Streptomyces coelicolor
Thermodynamics and Kinetics of Electron Transfer of Electrode-Immobilized Small Laccase from Streptomyces coelicolor Open
The thermodynamic and kinetic properties for heterogeneous electron transfer (ET) were measured for the electrode-immobilized small laccase (SLAC) from Streptomyces coelicolor subjected to different electrostatic and covalent protein-elect…
View article: Assessing the Functional and Structural Stability of the Met80Ala Mutant of Cytochrome c in Dimethylsulfoxide
Assessing the Functional and Structural Stability of the Met80Ala Mutant of Cytochrome c in Dimethylsulfoxide Open
The Met80Ala variant of yeast cytochrome c is known to possess electrocatalytic properties that are absent in the wild type form and that make it a promising candidate for biocatalysis and biosensing. The versatility of an enzyme is enhanc…
View article: Hydrogen peroxide induces heme degradation and protein aggregation in human neuroglobin: roles of the disulfide bridge and hydrogen‐bonding in the distal heme cavity
Hydrogen peroxide induces heme degradation and protein aggregation in human neuroglobin: roles of the disulfide bridge and hydrogen‐bonding in the distal heme cavity Open
In the present study, human neuroglobin (hNgb) was found to undergo H 2 O 2 ‐induced breakdown of the heme center at a much slower rate than other globins, namely in the timescale of hours against minutes. We investigated how the rate of t…
View article: Anti-Spoilage Activity and Exopolysaccharides Production by Selected Lactic Acid Bacteria
Anti-Spoilage Activity and Exopolysaccharides Production by Selected Lactic Acid Bacteria Open
In this study, eight lactic acid bacteria (LAB) strains, previously isolated from traditional and gluten-free sourdoughs, and selected for their potential in improving the sensory and rheological quality of bakery products, were screened a…
View article: Activity and substrate specificity of lytic polysaccharide monooxygenases: An <scp>ATR FTIR</scp>‐based sensitive assay tested on a novel species from <i>Pseudomonas putida</i>
Activity and substrate specificity of lytic polysaccharide monooxygenases: An <span>ATR FTIR</span>‐based sensitive assay tested on a novel species from <i>Pseudomonas putida</i> Open
Pseudomonas putida W619 is a soil Gram‐negative bacterium commonly used in environmental studies thanks to its ability in degrading many aromatic compounds. Its genome contains several putative carbohydrate‐active enzymes such as glycoside…
View article: Phosphodiesterase (PDE) 5 inhibitors sildenafil, tadalafil and vardenafil impact cAMP-specific PDE8 isoforms-linked second messengers and steroid production in a mouse Leydig tumor cell line
Phosphodiesterase (PDE) 5 inhibitors sildenafil, tadalafil and vardenafil impact cAMP-specific PDE8 isoforms-linked second messengers and steroid production in a mouse Leydig tumor cell line Open
View article: Pseudoperoxidase activity, conformational stability, and aggregation propensity of the His98Tyr myoglobin variant: implications for the onset of myoglobinopathy
Pseudoperoxidase activity, conformational stability, and aggregation propensity of the His98Tyr myoglobin variant: implications for the onset of myoglobinopathy Open
The autosomal dominant striated muscle disease myoglobinopathy is due to the single point mutation His98Tyr in human myoglobin (MB), the heme protein responsible for binding, storage, and controlled release of O 2 in striated muscle. In or…
View article: How to Turn an Electron Transfer Protein into a Redox Enzyme for Biosensing
How to Turn an Electron Transfer Protein into a Redox Enzyme for Biosensing Open
Cytochrome c is a small globular protein whose main physiological role is to shuttle electrons within the mitochondrial electron transport chain. This protein has been widely investigated, especially as a paradigmatic system for understand…
View article: The enthalpic and entropic terms of the reduction potential of metalloproteins: Determinants and interplay
The enthalpic and entropic terms of the reduction potential of metalloproteins: Determinants and interplay Open
View article: Electron Transfer and Electrocatalytic Properties of the Immobilized Met80Ala Cytochrome <i>c</i> Variant in Dimethylsulfoxide
Electron Transfer and Electrocatalytic Properties of the Immobilized Met80Ala Cytochrome <i>c</i> Variant in Dimethylsulfoxide Open
The electrode‐immobilized Met80Ala variant of yeast iso‐1 cytochrome c in mixed water/dimethylsulfoxide (DMSO) solutions up to 60 % v/v DMSO shows thermodynamic and kinetic parameters of electron exchange and electrocatalytic properties to…
View article: Sphingosine-1 phosphate induces cAMP/PKA-independent phosphorylation of the cAMP response element-binding protein (CREB) in granulosa cells
Sphingosine-1 phosphate induces cAMP/PKA-independent phosphorylation of the cAMP response element-binding protein (CREB) in granulosa cells Open
View article: Urea-induced denaturation of immobilized yeast iso-1 cytochrome c: Role of Met80 and Tyr67 in the thermodynamics of unfolding and promotion of pseudoperoxidase and nitrite reductase activities
Urea-induced denaturation of immobilized yeast iso-1 cytochrome c: Role of Met80 and Tyr67 in the thermodynamics of unfolding and promotion of pseudoperoxidase and nitrite reductase activities Open
View article: Electrochemical data on redox properties of human Cofilin-2 and its Mutant S3D
Electrochemical data on redox properties of human Cofilin-2 and its Mutant S3D Open
View article: Phosphorylated cofilin-2 is more prone to oxidative modifications on Cys39 and favors amyloid fibril formation
Phosphorylated cofilin-2 is more prone to oxidative modifications on Cys39 and favors amyloid fibril formation Open
View article: Adsorbing surface strongly influences the pseudoperoxidase and nitrite reductase activity of electrode-bound yeast cytochrome c. The effect of hydrophobic immobilization
Adsorbing surface strongly influences the pseudoperoxidase and nitrite reductase activity of electrode-bound yeast cytochrome c. The effect of hydrophobic immobilization Open
View article: Binding of S. cerevisiae iso-1 cytochrome c and its surface lysine-to-alanine variants to cardiolipin: charge effects and the role of the lipid to protein ratio
Binding of S. cerevisiae iso-1 cytochrome c and its surface lysine-to-alanine variants to cardiolipin: charge effects and the role of the lipid to protein ratio Open
View article: Met80 and Tyr67 affect the chemical unfolding of yeast cytochrome<i>c</i>: comparing the solution<i>vs.</i>immobilized state
Met80 and Tyr67 affect the chemical unfolding of yeast cytochrome<i>c</i>: comparing the solution<i>vs.</i>immobilized state Open
The motional regime affects the unfolding propensity and axial heme coordination of the Met80Ala and Met80Ala/Tyr67Ala variants of yeast iso-1 cytochromec.
View article: Electrocatalytic Properties of Immobilized Heme Proteins: Basic Principles and Applications
Electrocatalytic Properties of Immobilized Heme Proteins: Basic Principles and Applications Open
Heme proteins encompass redox enzymes, electron transferases, and species for dioxygen transport and storage. Upon immobilization on a conductive surface, heme proteins can accomplish bioelectrocatalysis. In this process, they carry out ox…
View article: Enamel peptides reveal the sex of the Late Antique ‘Lovers of Modena’
Enamel peptides reveal the sex of the Late Antique ‘Lovers of Modena’ Open