Giulia Lorenzoni
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View article: Propensity score analysis of stented versus rapid deployment aortic bioprostheses in patients with small aortic annulus
Propensity score analysis of stented versus rapid deployment aortic bioprostheses in patients with small aortic annulus Open
Objectives Haemodynamic studies have demonstrated the excellent performance of rapid deployment (RD) valves. This retrospective single-centre study aimed to compare early and medium-term outcomes of RD bioprostheses versus conventional ste…
View article: Quality of Life After Pancreatic Surgery for Neuroendocrine Tumors of the Pancreas: Observational Study of Long-Term Outcomes
Quality of Life After Pancreatic Surgery for Neuroendocrine Tumors of the Pancreas: Observational Study of Long-Term Outcomes Open
Background/Objectives: Patients with pancreatic neuroendocrine tumors (PanNETs) often have a good prognosis with long overall survival. We evaluated quality of life (QoL) after surgery for PanNETs, using the new EORTC-specific questionnair…
View article: Assessing the Accuracy and Readability of Large Language Model Guidance for Patients on Breast Cancer Surgery Preparation and Recovery
Assessing the Accuracy and Readability of Large Language Model Guidance for Patients on Breast Cancer Surgery Preparation and Recovery Open
Background/Objectives: Accurate and accessible perioperative health information empowers patients and enhances recovery outcomes. Artificial intelligence tools, such as ChatGPT, have garnered attention for their potential in health communi…
View article: Outcome and Disease Progression in NYHA Functional Class I and II Patients With Wild-Type Transthyretin Cardiomyopathy Treated With Tafamidis
Outcome and Disease Progression in NYHA Functional Class I and II Patients With Wild-Type Transthyretin Cardiomyopathy Treated With Tafamidis Open
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View article: Attitudes Toward Alternative Tobacco and Nicotine Products and Their Association With Lifestyle Habits: Protocol for the MINERVA International Observational Cohort Study
Attitudes Toward Alternative Tobacco and Nicotine Products and Their Association With Lifestyle Habits: Protocol for the MINERVA International Observational Cohort Study Open
Background Traditional smoking is widely recognized as a public health issue, with established risks that include cardiovascular, respiratory, and cancer-related health impacts. Recently, alternative tobacco and nicotine products (ATNPs), …
View article: Quality of life after Pancreatic Surgery for Neuroendocrine Tumors of the Pancreas: Long-term outcomes of 100 patients evaluated with new EORTC questionnaires
Quality of life after Pancreatic Surgery for Neuroendocrine Tumors of the Pancreas: Long-term outcomes of 100 patients evaluated with new EORTC questionnaires Open
Background Patients with Pancreatic Neuroendocrine Tumors (PanNETs) often have a good prognosis with long overall survival. We evaluated Quality of Life (QoL) after surgery for PanNETs, using the new EORTC specific questionnaires. Methods …
View article: Predicted vs. Observed Prosthesis–Patient Mismatch After Surgical Aortic Valve Replacement
Predicted vs. Observed Prosthesis–Patient Mismatch After Surgical Aortic Valve Replacement Open
Background and Objectives: Prosthesis–patient mismatch (PPM) after surgical aortic valve replacement (SAVR) is associated with worse clinical outcomes and worse valve durability. The aim of this retrospective single-center study was to eva…
View article: Large Language Models in Action: Supporting Clinical Evaluation in an Infectious Disease Unit
Large Language Models in Action: Supporting Clinical Evaluation in an Infectious Disease Unit Open
Background/Objectives: Healthcare-associated infections (HAIs), including sepsis, represent a major challenge in clinical practice owing to their impact on patient outcomes and healthcare systems. Large language models (LLMs) offer a poten…
View article: Robotic Thymectomy for Myasthenia Gravis: Analysis of the Surgical and Neurological Outcomes After a 20 Years' Experience
Robotic Thymectomy for Myasthenia Gravis: Analysis of the Surgical and Neurological Outcomes After a 20 Years' Experience Open
Background Evidence supporting robotic thymectomy for myasthenia gravis is generally based on small sample‐size studies, heterogeneous in patient selection and in reporting outcomes. Therefore, this study was conducted to assess the surgic…
View article: Cryoanalgesia for Pain Management After Pectus Excavatum Repair (COPPER) in Adolescents: A Randomized Controlled Trial
Cryoanalgesia for Pain Management After Pectus Excavatum Repair (COPPER) in Adolescents: A Randomized Controlled Trial Open
Background Patients undergoing Pectus Excavatum repair with the minimally invasive approach frequently report severe postoperative pain. The goal of the study is to determine the superiority of cryoanalgesia compared to standard of care fo…
View article: A Large Language Model-Based Approach for Coding Information from Free-Text Reported in Fall Risk Surveillance Systems: New Opportunities for In-Hospital Risk Management
A Large Language Model-Based Approach for Coding Information from Free-Text Reported in Fall Risk Surveillance Systems: New Opportunities for In-Hospital Risk Management Open
Background/Objectives: Falls are the most common adverse in-hospital event, resulting in a considerable social and economic burden on individuals, their families, and the healthcare system. This study aims to develop and implement an autom…
View article: Clinical outcomes of avelumab and pembrolizumab in advanced urothelial cancer: an observational multicenter retro-prospective study on patients undergoing treatment in clinical practice (AVePEm study)
Clinical outcomes of avelumab and pembrolizumab in advanced urothelial cancer: an observational multicenter retro-prospective study on patients undergoing treatment in clinical practice (AVePEm study) Open
Introduction and objectives Patients (pts) with metastatic urothelial carcinoma (mUC) gain substantial benefit from immunotherapy exposure. If they do not experience disease progression after 4-6 cycles of first-line platinum-based chemoth…
View article: Non-Invasive Ventilation Failure in Pediatric ICU: A Machine Learning Driven Prediction
Non-Invasive Ventilation Failure in Pediatric ICU: A Machine Learning Driven Prediction Open
Background/Objectives: Non-invasive ventilation (NIV) has emerged as a possible first-step treatment to avoid invasive intubation in pediatric intensive care units (PICUs) due to its advantages in reducing intubation-associated risks. Howe…
View article: Bayesan Model to Predict R Status After Neoadjuvant Therapy in Pancreatic Cancer
Bayesan Model to Predict R Status After Neoadjuvant Therapy in Pancreatic Cancer Open
Objective: To build a Bayesian approach-based model to predict the success of surgical exploration post-neoadjuvant treatment. Background: Pancreatic cancer (PDAC) is best treated with radical surgery and chemotherapy, offering the greates…
View article: Prognostic Assessment with the Malnutrition Universal Screening Tool in Heart Transplant Recipients: A Pilot Study and a Single-Center Experience
Prognostic Assessment with the Malnutrition Universal Screening Tool in Heart Transplant Recipients: A Pilot Study and a Single-Center Experience Open
Introduction and aims: Malnutrition is associated with increased morbidity and mortality in patients who undergo cardiac surgery. Nevertheless, objective assessment of malnourished patients undergoing heart transplantation (HT) is limited.…
View article: Impact of Updated Invasive Right Ventricular and Pulmonary Hemodynamics on Long-Term Outcomes in Patients With Mitral Valve Transcatheter Edge-to-Edge Repair
Impact of Updated Invasive Right Ventricular and Pulmonary Hemodynamics on Long-Term Outcomes in Patients With Mitral Valve Transcatheter Edge-to-Edge Repair Open
Right-sided cardiac catheterization (RHC) is selectively recommended in mitral valve transcatheter edge-to-edge (M-TEER) workup because right ventricle (RV) hemodynamic parameters predict adverse outcomes. This study examines the impact of…
View article: Long-term survival after TAVI in low-flow, low-gradient aortic valve stenosis
Long-term survival after TAVI in low-flow, low-gradient aortic valve stenosis Open
Classical LFLG-AS patients had lower long-term survival rates as compared to pLFLG-AS and HG-AS patients. However, after adjustment for possible baseline confounders, a low-flow status per se did not have an impact on long-term mortality a…
View article: Bayesian Dynamic Borrowing in Group-Sequential Design for Medical Device Studies
Bayesian Dynamic Borrowing in Group-Sequential Design for Medical Device Studies Open
Background Medical device technology evolves rapidly, with shorter lifecycles compared to pharmaceuticals. This acceleration necessitates swift safety and efficacy assessments to keep pace with technological advancements. In this context, …
View article: Sleep Patterns, Social Media Usage, and Dietary Habits during COVID-19 Lockdown in Mexico: A Cross-Sectional Study
Sleep Patterns, Social Media Usage, and Dietary Habits during COVID-19 Lockdown in Mexico: A Cross-Sectional Study Open
During the COVID-19 lockdown, a high prevalence of disruption in lifestyle habits was reported, especially concerning sleep habits. The present study aimed to explore the relationship between lifestyles and the COVID-19 lockdown on subject…
View article: Safety and Efficacy of Salvage Surgery after Treatment With Immune‐Checkpoint Adjuvant Inhibitors for Advanced Non‐Small Cell Lung Cancer: A Multicentric Study
Safety and Efficacy of Salvage Surgery after Treatment With Immune‐Checkpoint Adjuvant Inhibitors for Advanced Non‐Small Cell Lung Cancer: A Multicentric Study Open
Objective In advanced non‐small cell lung cancer (NSCLC), immune‐checkpoint inhibitors (ICIs) can achieve significant clinical responses. This raises the question of whether to consider salvage surgery as a curative treatment option. Few c…