Giulia Roda
YOU?
Author Swipe
View article: Human Leukocyte Antigen Signatures as Pathophysiological Discriminants of Microscopic Colitis Subtypes
Human Leukocyte Antigen Signatures as Pathophysiological Discriminants of Microscopic Colitis Subtypes Open
Background and Aims Microscopic colitis [MC] is currently regarded as an inflammatory bowel disease that manifests as two subtypes: collagenous colitis [CC] and lymphocytic colitis [LC]. Whether these represent a clinical continuum or dist…
View article: Pomegranate Extract Affects Gut Biofilm Forming Bacteria and Promotes Intestinal Mucosal Healing Regulating the Crosstalk between Epithelial Cells and Intestinal Fibroblasts
Pomegranate Extract Affects Gut Biofilm Forming Bacteria and Promotes Intestinal Mucosal Healing Regulating the Crosstalk between Epithelial Cells and Intestinal Fibroblasts Open
Background: Pomegranate (Punica granatum) can be used to prepare a bioactive extract exerting anti-inflammatory activities. Clinical studies demonstrated an improvement in clinical response in inflammatory bowel disease (IBD) patients when…
View article: Dysfunctional Extracellular Matrix Remodeling Supports Perianal Fistulizing Crohn′s Disease by a Mechanoregulated Activation of the Epithelial-to-Mesenchymal Transition
Dysfunctional Extracellular Matrix Remodeling Supports Perianal Fistulizing Crohn′s Disease by a Mechanoregulated Activation of the Epithelial-to-Mesenchymal Transition Open
By mediating changes in the ECM organization, TSG-6 triggers the epithelial-mesenchymal transition transcription factor SNAI1 through the activation of mechanosensitive proteins. These data point to regulators of ECM as new potential targe…
View article: New Insights into Bile Acids Related Signaling Pathways in the Onset of Colorectal Cancer
New Insights into Bile Acids Related Signaling Pathways in the Onset of Colorectal Cancer Open
Colorectal cancer (CRC) ranks as the second among the causes of tumor death worldwide, with an estimation of 1.9 million new cases in 2020 and more than 900,000 deaths. This rate might increase by 60% over the next 10 years. These data are…
View article: Ileal Pouch–Anal Anastomosis and Pouchitis: The Role of the Microbiota in the Pathogenesis and Therapy
Ileal Pouch–Anal Anastomosis and Pouchitis: The Role of the Microbiota in the Pathogenesis and Therapy Open
Inflammatory bowel diseases, Crohn’s disease and ulcerative colitis, are life-long disorders characterized by the chronic relapsing inflammation of the gastrointestinal tract with the intermittent need for escalation treatment and, eventua…
View article: Bakery Products Enriched with Eruca Sativa Mill Defatted Seed Meal Ameliorates Systemic Markers of Inflammation and Glucose and Lipid Metabolism in Adults- A Pilot Study
Bakery Products Enriched with Eruca Sativa Mill Defatted Seed Meal Ameliorates Systemic Markers of Inflammation and Glucose and Lipid Metabolism in Adults- A Pilot Study Open
Introduction:Most patients with metabolic syndrome present non-alcoholic fatty liver disease (NAFD).High consumption of fruit and vegetable has been related to a lower incidence of chronic diseases.Of note, among vegetables, brassicaceae f…
View article: Endoscopic Surveillance in Inflammatory Bowel Diseases: Selecting a Suitable Technology
Endoscopic Surveillance in Inflammatory Bowel Diseases: Selecting a Suitable Technology Open
In the treat-to-target era, endoscopy has become the backbone of the assessment of remission, defined as mucosal healing, in inflammatory bowel disease (IBD) patients. Current recommendations indicate that endoscopic procedures should be p…
View article: Diversion proctocolitis and the problem of the forgotten rectum in inflammatory bowel diseases: A systematic review
Diversion proctocolitis and the problem of the forgotten rectum in inflammatory bowel diseases: A systematic review Open
Background and aims Diversion proctocolitis (DP) is a non‐specific mucosal inflammation arising in the defunctionalized colon and/or rectum following faecal diversion (colostomy, ileostomy). Differential diagnosis of DP from the underlying…
View article: Health coaching experience in Minerbio (Italy): Global impact on weight, BMI, waist circumference and blood pressure
Health coaching experience in Minerbio (Italy): Global impact on weight, BMI, waist circumference and blood pressure Open
In the last decade, growing evidence have shown the cardioprotective role of the Mediterranean diet. Health coaching has a pivotal role in primary care, helping patients to self-education concerning diet and physical activity. Our study is…
View article: The IL23-IL17 Immune Axis in the Treatment of Ulcerative Colitis: Successes, Defeats, and Ongoing Challenges
The IL23-IL17 Immune Axis in the Treatment of Ulcerative Colitis: Successes, Defeats, and Ongoing Challenges Open
Ulcerative colitis (UC) is a chronic relapsing disorder of the colonic tract, characterized by a dysregulated innate and adaptive immune response to gut microbiota that contributes to the perpetuation of intestinal inflammatory processes. …
View article: Dataset related to article "Validation of the Red Flags Index for Early Diagnosis of Crohn's Disease: A Prospective Observational IG-IBD Study Among General Practitioners"
Dataset related to article "Validation of the Red Flags Index for Early Diagnosis of Crohn's Disease: A Prospective Observational IG-IBD Study Among General Practitioners" Open
This record contains raw data related to article "Validation of the Red Flags Index for Early Diagnosis of Crohn's Disease: A Prospective Observational IG-IBD Study Among General Practitioners" Diagnostic delay >12 months is frequent in Cr…
View article: Dataset related to article "Validation of the Red Flags Index for Early Diagnosis of Crohn's Disease: A Prospective Observational IG-IBD Study Among General Practitioners"
Dataset related to article "Validation of the Red Flags Index for Early Diagnosis of Crohn's Disease: A Prospective Observational IG-IBD Study Among General Practitioners" Open
This record contains raw data related to article "Validation of the Red Flags Index for Early Diagnosis of Crohn's Disease: A Prospective Observational IG-IBD Study Among General Practitioners" Diagnostic delay >12 months is frequent in Cr…
View article: Slow Release Oral Formulation and Topical Curcumin in Combination with 5 Aminosalycilate Induce Remission in Patients with Refractory Ulcerative Proctitis in A Randomized Controlled Trial
Slow Release Oral Formulation and Topical Curcumin in Combination with 5 Aminosalycilate Induce Remission in Patients with Refractory Ulcerative Proctitis in A Randomized Controlled Trial Open
Introduction and Aim: Refractory ulcerative proctitis is defined as the failure of topical and oral 5-aminosalicylate and corticosteroids treatment. Management of refractory proctitis is often challenging. Curcumin was reported to be effic…
View article: Dataset related to article "Hyaluronan Accelerates Intestinal Mucosal Healing through Interaction with TSG-6."
Dataset related to article "Hyaluronan Accelerates Intestinal Mucosal Healing through Interaction with TSG-6." Open
Hyaluronan (HA) has proven to be beneficial in the treatment of several diseases. Recently, it has been shown that the local application of HA (IBD98E) improves endoscopic and clinical outcomes in subjects with active distal ulcerative col…
View article: Dataset related to article "Hyaluronan Accelerates Intestinal Mucosal Healing through Interaction with TSG-6."
Dataset related to article "Hyaluronan Accelerates Intestinal Mucosal Healing through Interaction with TSG-6." Open
Hyaluronan (HA) has proven to be beneficial in the treatment of several diseases. Recently, it has been shown that the local application of HA (IBD98E) improves endoscopic and clinical outcomes in subjects with active distal ulcerative col…
View article: DOP66 A CEACAM5 small peptide restores the suppressive activity of CD8 + T cells in patients with Crohn’s disease
DOP66 A CEACAM5 small peptide restores the suppressive activity of CD8 + T cells in patients with Crohn’s disease Open
Background Intestinal epithelial cells (IECs) play a pivotal role in controlling immune responses by activation of suppressive CD8+ T regulatory cells (Treg). In Crohn’s disease (CD) this response is impaired due to a defect in CEACAM5 exp…
View article: P244 Validation of the Red Flags index for early diagnosis of Crohn’s disease: A prospective general practitioner study
P244 Validation of the Red Flags index for early diagnosis of Crohn’s disease: A prospective general practitioner study Open
Background A diagnostic delay >12 months is frequent in Crohn’s disease (CD), and associated with lower therapeutic response rates and worse outcomes. The Red Flags index, a simple tool to help to identify early CD and reduce diagnostic…
View article: P827 The clinical phenotype of collagenous colitis is associated with T-cell-related genetic variants
P827 The clinical phenotype of collagenous colitis is associated with T-cell-related genetic variants Open
Background Collagenous colitis (CC) is a common cause of chronic diarrhoea and highly associated with immune-mediated diseases. The aetiology of CC may involve a dysregulated immune response in genetically predisposed individuals. Our prel…
View article: P747 Adherence to ECCO guidelines for cancer surveillance is associated to the detection of early cancer: A retrospective, single-centre, cohort study
P747 Adherence to ECCO guidelines for cancer surveillance is associated to the detection of early cancer: A retrospective, single-centre, cohort study Open
Background Patients with inflammatory bowel disease (IBD), such as ulcerative colitis (UC) and Crohn’s disease (CD) are at increased risk of developing gastrointestinal (GI) malignancies. The aim of this study is to assess the risk of mali…
View article: DOP63 Efficacy and safety of iron carboxymaltose on chronic fatigue in patients with inflammatory bowel disease: a randomised controlled trial
DOP63 Efficacy and safety of iron carboxymaltose on chronic fatigue in patients with inflammatory bowel disease: a randomised controlled trial Open
Background Patients with inflammatory bowel diseases (IBD) have an altered quality of life, also due to chronic fatigue (CF). Iron administration is effective in iron deficiency associated with CF in patients with heart failure. Our hypoth…
View article: Hyaluronan Accelerates Intestinal Mucosal Healing through Interaction with TSG-6
Hyaluronan Accelerates Intestinal Mucosal Healing through Interaction with TSG-6 Open
Hyaluronan (HA) has proven to be beneficial in the treatment of several diseases. Recently, it has been shown that the local application of HA (IBD98E) improves endoscopic and clinical outcomes in subjects with active distal ulcerative col…
View article: Serum Bile Acids Profiling in Inflammatory Bowel Disease Patients Treated with Anti-TNFs
Serum Bile Acids Profiling in Inflammatory Bowel Disease Patients Treated with Anti-TNFs Open
Background: Inflammatory bowel diseases (IBD), ulcerative colitis (UC), and Crohn’s disease (CD), represent systematic chronic conditions with a deficient intestinal absorption. We first attempt to investigate the serum bile acids (sBAs) p…