Giulia Ruffini
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View article: Ice2 promotes ER membrane biogenesis in yeast by inhibiting the conserved lipin phosphatase complex
Ice2 promotes ER membrane biogenesis in yeast by inhibiting the conserved lipin phosphatase complex Open
Cells dynamically adapt organelle size to current physiological demand. Organelle growth requires membrane biogenesis and therefore needs to be coordinated with lipid metabolism. The endoplasmic reticulum (ER) can undergo massive expansion…
View article: Ice2 promotes ER membrane biogenesis in yeast by inhibiting the conserved lipin phosphatase complex
Ice2 promotes ER membrane biogenesis in yeast by inhibiting the conserved lipin phosphatase complex Open
Cells dynamically adapt organelle size to current physiological demand. Organelle growth requires membrane biogenesis and therefore needs to be coordinated with lipid metabolism. The endoplasmic reticulum (ER) can undergo massive expansion…
View article: ESCRT machinery mediates selective microautophagy of endoplasmic reticulum
ESCRT machinery mediates selective microautophagy of endoplasmic reticulum Open
ER-phagy, the selective autophagy of endoplasmic reticulum (ER), safeguards organelle homeostasis by eliminating misfolded proteins and regulating ER size. ER-phagy can occur by macroautophagic and microautophagic mechanisms. While dedicat…