Giulia Traini
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View article: Association Among Sperm Adiponectin, DNA Fragmentation, Oxidative Stress and Metabolites in Male Infertility
Association Among Sperm Adiponectin, DNA Fragmentation, Oxidative Stress and Metabolites in Male Infertility Open
Infertility is a widespread global problem, with a male factor contributing to approximately 40–50% of cases. Several studies have investigated the involvement of adipokines in reproductive functions, but only a few have investigated their…
View article: P-028 Optimizing sperm selection: A comparison of the Microfluidic device and Swim-up technique in samples with compromised semen quality
P-028 Optimizing sperm selection: A comparison of the Microfluidic device and Swim-up technique in samples with compromised semen quality Open
Study question Does the microfluidic device select high-quality spermatozoa from samples with compromised semen quality? Summary answer Microfluidics selects high-quality spermatozoa compared to Swim-up technique, even in samples with comp…
View article: Microfluidic Sorting Can Be Applied for Assisted Reproduction Sperm Selection in Different Cases of Semen Abnormalities
Microfluidic Sorting Can Be Applied for Assisted Reproduction Sperm Selection in Different Cases of Semen Abnormalities Open
Sperm preparation is a critical step in assisted reproduction, aiming to isolate spermatozoa with optimal characteristics and high fertilizing potential. Traditional sperm selection methods involve centrifugation, which may cause sperm dam…
View article: Semen cryopreservation and storage in liquid nitrogen: Impact on chromatin compaction
Semen cryopreservation and storage in liquid nitrogen: Impact on chromatin compaction Open
Background Sperm cryopreservation is a consolidate option for long‐term male fertility preservation. The freezing/thawing procedure causes detrimental effects to spermatozoa, including damage to viability, motility, membrane composition, a…
View article: P-054 Paternal age and cryopreservation impact sperm chromatin status as indicated by changes in protamine and histone levels
P-054 Paternal age and cryopreservation impact sperm chromatin status as indicated by changes in protamine and histone levels Open
Study question Do paternal age and cryopreservation alter sperm chromatin status in normospermic men? Summary answer Paternal age and cryopreservation appear to impact sperm chromatin condensation by altering protamine and histone DNA leve…
View article: Sperm Chromatin Dispersion Test Detects Sperm DNA Fragmentation Mainly Associated with Unviable Spermatozoa and Underestimates the Values with Respect to TUNEL Assay
Sperm Chromatin Dispersion Test Detects Sperm DNA Fragmentation Mainly Associated with Unviable Spermatozoa and Underestimates the Values with Respect to TUNEL Assay Open
Several clinical laboratories assess sperm DNA fragmentation (sDF) in addition to semen analysis in male infertility diagnosis. Among tests evaluating sDF, TUNEL (Terminal deoxynucleotidyl transferase dUTP nick end labeling) and SCD (Sperm…
View article: Effects of Benzo[a]pyrene on Human Sperm Functions: An In Vitro Study
Effects of Benzo[a]pyrene on Human Sperm Functions: An In Vitro Study Open
Benzo(a)pyrene (BaP) is considered one of the most dangerous air pollutants for adverse health effects, including reproductive toxicity. It is found both in male and female reproductive fluids likely affecting spermatozoa after the selecti…
View article: Semen Cryopreservation for Men Banking for Oligozoospermia, Cancers, and Other Conditions: 24 Years’ Experience of an Italian Bank
Semen Cryopreservation for Men Banking for Oligozoospermia, Cancers, and Other Conditions: 24 Years’ Experience of an Italian Bank Open
Background: Sperm cryopreservation is recommended to preserve male fertility for cancer patients or other medical conditions at risk of sperm decline. Whether motility and viability recovery rates vary depending on the medical conditions r…
View article: P-056 Oxidative stress and human semen quality: new results for diagnostic process of male infertility
P-056 Oxidative stress and human semen quality: new results for diagnostic process of male infertility Open
Study question Is oxidative stress (OS) evaluated in human spermatozoa a predictive marker of better semen quality? Summary answer CellROX®Orange is a new fluorescent probe able to detect Reactive Oxygen Species (ROS) identifying a viable …
View article: Cryopreservation of Human Spermatozoa: Functional, Molecular and Clinical Aspects
Cryopreservation of Human Spermatozoa: Functional, Molecular and Clinical Aspects Open
Cryopreservation is an expanding strategy to allow not only fertility preservation for individuals who need such procedures because of gonadotoxic treatments, active duty in dangerous occupations or social reasons and gamete donation for c…
View article: Is oxidative stress evaluated in viable human spermatozoa a marker of good semen quality?
Is oxidative stress evaluated in viable human spermatozoa a marker of good semen quality? Open
Background Oxidative stress is defined as the unbalance between reactive oxygen species (ROS) production and antioxidant defences. Whereas low levels of ROS are necessary for physiological sperm functions, high levels impair fertility dama…