Giuseppe Ippolito
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View article: Global health at crossroads: uniting together to overcome challenges, restore trust and advance priorities for a sustainable future
Global health at crossroads: uniting together to overcome challenges, restore trust and advance priorities for a sustainable future Open
View article: A cocktail of SARS-CoV-2 spike stem helix domain and receptor binding domain human monoclonal antibodies prevent the emerge of viral escape mutants
A cocktail of SARS-CoV-2 spike stem helix domain and receptor binding domain human monoclonal antibodies prevent the emerge of viral escape mutants Open
Neutralizing antibodies (NAbs) targeting the spike (S) glycoprotein remain a crucial therapeutic strategy against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, emerging viral variants have escaped all Food and Drug…
View article: Rising tide of Vector-Borne Diseases in Europe - Surveillance, Clinical Awareness, and Public Health Preparedness
Rising tide of Vector-Borne Diseases in Europe - Surveillance, Clinical Awareness, and Public Health Preparedness Open
View article: Protecting the future of vaccine development amidst US funding withdrawal for mRNA vaccine research
Protecting the future of vaccine development amidst US funding withdrawal for mRNA vaccine research Open
View article: Prolonged survival in a HER2 positive metastatic breast cancer patient with brain metastases treated with TDM1 after failure of next generation HER2 targeted therapies
Prolonged survival in a HER2 positive metastatic breast cancer patient with brain metastases treated with TDM1 after failure of next generation HER2 targeted therapies Open
Background: Brain metastases (BM) occur in up to 50% of patients with HER2-positive metastatic breast cancer (MBC) and represent a major clinical challenge due to limited CNS drug penetration. In recent years, novel anti-HER2 agents—such a…
View article: Pathologic Complete Response in Triple Negative Breast Cancer Treated with Anthracycline Free Regimen: a case report
Pathologic Complete Response in Triple Negative Breast Cancer Treated with Anthracycline Free Regimen: a case report Open
Triple-negative breast cancer (TNBC) is a highly aggressive malignancy with limited therapeutic options and elevated mortality rates. Chemo-immunotherapy according to the KEYNOTE-522 has established a new standard of care in the neoadjuvan…
View article: 402P Fracture risk in metastatic breast cancer patients treated with CDK 4/6 inhibitors and endocrine therapy
402P Fracture risk in metastatic breast cancer patients treated with CDK 4/6 inhibitors and endocrine therapy Open
View article: Global Resurgence of Measles: Turning the Tide through a Bold Agenda for Prevention and Control
Global Resurgence of Measles: Turning the Tide through a Bold Agenda for Prevention and Control Open
View article: Corrigendum to “Characterisation of transfusion-dependent prediabetes using continuous glucose monitoring: The Haemoglycare study” [Diab. Res. Clin. Pract. 222 (2025) 112076]
Corrigendum to “Characterisation of transfusion-dependent prediabetes using continuous glucose monitoring: The Haemoglycare study” [Diab. Res. Clin. Pract. 222 (2025) 112076] Open
View article: Perspectives on tuberculosis in migrants, refugees, and displaced populations in Europe
Perspectives on tuberculosis in migrants, refugees, and displaced populations in Europe Open
Finding and treating all forms of tuberculosis (TB) (latent, drug-susceptible, drug-resistant, multidrug-resistant, and extensively drug-resistant tuberculosis) among migrants, displaced populations, and refugees are important challenges f…
View article: Characterisation of transfusion-dependent prediabetes using continuous glucose monitoring: The Haemoglycare study
Characterisation of transfusion-dependent prediabetes using continuous glucose monitoring: The Haemoglycare study Open
CGM reliably detects prediabetes in 37 % of TDT patients. TAR140 > 6 % may serve as a diagnostic cutoff.
View article: Avian Influenza – The next travel-associated pandemic? Proactive One Health surveillance is required to reduce the risk of the spread
Avian Influenza – The next travel-associated pandemic? Proactive One Health surveillance is required to reduce the risk of the spread Open
View article: Changes in body composition in early breast cancer patients treated with aromatase inhibitors
Changes in body composition in early breast cancer patients treated with aromatase inhibitors Open
Purpose The aim of the study was to analyze the modification of total and regional body composition in early breast cancer patients treated with aromatase inhibitors (AIs). Methods This is a prospective, single-center, observational, longi…
View article: Gastrointestinal Toxicity of Antibody Drug Conjugates (ADCs) in Metastatic Breast Cancer: A Pooled Analysis
Gastrointestinal Toxicity of Antibody Drug Conjugates (ADCs) in Metastatic Breast Cancer: A Pooled Analysis Open
View article: Gian Maria Fimia (1967–2024), an outstanding scientist with immense human qualities
Gian Maria Fimia (1967–2024), an outstanding scientist with immense human qualities Open
View article: On the trail of the novel coronavirus at the start of the pandemic in the Lazio region: a retrospective research of SARS-CoV-2 in nasopharyngeal swabs.
On the trail of the novel coronavirus at the start of the pandemic in the Lazio region: a retrospective research of SARS-CoV-2 in nasopharyngeal swabs. Open
SARS-CoV-2 RNA was not detected in 219 nasal/oro-pharyngeal swabs, analyzed for respiratory disease diagnosis at the National Institute for Infectious Diseases “Lazzaro Spallanzani”, from November 2019 to January 2020; these results sugges…
View article: Is weight gain preventable in women with early breast cancer undergoing chemotherapy? A real-world study on dietary pattern, physical activity, and body weight before and after chemotherapy
Is weight gain preventable in women with early breast cancer undergoing chemotherapy? A real-world study on dietary pattern, physical activity, and body weight before and after chemotherapy Open
Purpose We aimed to investigate the role of a lifestyle intervention and clinical and therapeutic factors for preventing weight gain in early breast cancer (BC) patients from one week before to 12 months after chemotherapy. Methods Dietary…
View article: Aero-Medical Evacuation during SARS-CoV-2 Pandemic: Extraordinary Measure or Emerging Treatment Option?
Aero-Medical Evacuation during SARS-CoV-2 Pandemic: Extraordinary Measure or Emerging Treatment Option? Open
Aero-medical evacuation has been considered as a feasible and safe treatment option during COVID pandemic, particularly when the needs of affected patients exceed what local clinics and hospitals are supposed to provide. In this article, w…
View article: Telemedicine During COVID-19 Pandemic: Lesson Learned from the Lazio Region Infectious Diseases and Emergency Department Network
Telemedicine During COVID-19 Pandemic: Lesson Learned from the Lazio Region Infectious Diseases and Emergency Department Network Open
Telemedicine and teleconsultation can be powerful and useful tools for patients to hamper the physical barriers to access to health care services during COVID-19 pandemic. We describe the teleconsultation (TC) model in the Lazio Region. It…
View article: ‘Disease X’—time to act now and prepare for the next pandemic threat
‘Disease X’—time to act now and prepare for the next pandemic threat Open
View article: Long-term effect of SARS-CoV-2 infection on cardiovascular outcomes and all-cause mortality
Long-term effect of SARS-CoV-2 infection on cardiovascular outcomes and all-cause mortality Open
View article: The immune response as a double‐edged sword: The lesson learnt during the <scp>COVID</scp>‐19 pandemic
The immune response as a double‐edged sword: The lesson learnt during the <span>COVID</span>‐19 pandemic Open
The COVID‐19 pandemic has represented an unprecedented challenge for the humanity, and scientists around the world provided a huge effort to elucidate critical aspects in the fight against the pathogen, useful in designing public health st…
View article: Vaccination for monkeypox prevention in persons with high-risk sexual behaviours to control on-going outbreak of monkeypox virus clade 3.
Vaccination for monkeypox prevention in persons with high-risk sexual behaviours to control on-going outbreak of monkeypox virus clade 3. Open
View article: Immune response in COVID-19: what is next?
Immune response in COVID-19: what is next? Open
View article: Safety and serum distribution of anti-SARS-CoV-2 monoclonal antibody MAD0004J08 after intramuscular injection
Safety and serum distribution of anti-SARS-CoV-2 monoclonal antibody MAD0004J08 after intramuscular injection Open
View article: Deep learning-based single image super-resolution for low-field MR brain images
Deep learning-based single image super-resolution for low-field MR brain images Open
View article: Correction to: Plasma concentrations of remdesivir metabolite in a critical COVID-19 patient needing continuous venovenous haemodialysis
Correction to: Plasma concentrations of remdesivir metabolite in a critical COVID-19 patient needing continuous venovenous haemodialysis Open
View article: The interplay between SARS-CoV-2 infected airway epithelium and immune cells modulates regulatory/inflammatory signals
The interplay between SARS-CoV-2 infected airway epithelium and immune cells modulates regulatory/inflammatory signals Open
To assess the cross-talk between immune cells and respiratory tract during SARS-CoV-2 infection, we analyzed the relationships between the inflammatory response induced by SARS-CoV-2 replication and immune cells phenotype in a reconstitute…
View article: Analysis of HIV quasispecies and virological outcome of an HIV D+/R+ kidney–liver transplantation
Analysis of HIV quasispecies and virological outcome of an HIV D+/R+ kidney–liver transplantation Open
View article: Additional file 3 of Proteomic analysis identifies a signature of disease severity in the plasma of COVID-19 pneumonia patients associated to neutrophil, platelet and complement activation
Additional file 3 of Proteomic analysis identifies a signature of disease severity in the plasma of COVID-19 pneumonia patients associated to neutrophil, platelet and complement activation Open
Additional file 3: Table S3: MaxQuant software identification of proteins from plasma of COVID-19 patients.