Gökhan Artaş
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View article: The Regulatory Effects of Exercise and Metformin on Biomarkers in Obesity: A Focus on Uric Acid, Irisin, Adiponutrin, Adropin, and Copeptin
The Regulatory Effects of Exercise and Metformin on Biomarkers in Obesity: A Focus on Uric Acid, Irisin, Adiponutrin, Adropin, and Copeptin Open
Background and Objectives: Obesity has become one of the most significant health problems nowadays, with its prevalence rapidly increasing. Approaches such as diet and exercise play an important role in the treatment of obesity. This study…
View article: Effect of Different Administered Doses of Capsaicin and Titanium Implant Osseointegration
Effect of Different Administered Doses of Capsaicin and Titanium Implant Osseointegration Open
Background and Objectives: This study aimed to evaluate the histological and biochemical effects of capsaicin on implant osseointegration and oxidative stress. Materials and Methods: Male Wistar albino rats weighing between 250 and 300 g w…
View article: Effect of Different Doses of Capsaicin Administration and Titanium Implant Osseointegration
Effect of Different Doses of Capsaicin Administration and Titanium Implant Osseointegration Open
Background and Objectives: This study aimed to evaluate the histological and biochemical ef-fects of capsaicin on implant osseointegration and oxidative stress. Materials and Methods: Male Wistar albino rats weighing between 250 and 300 gr…
View article: Investigation of Hyaluronan Synthase 2 and CD44 immune reactivity as a biomarker to predict Progesterone-Resistant Endometrial Hyperplasia without atypia: A retrospective case-control study
Investigation of Hyaluronan Synthase 2 and CD44 immune reactivity as a biomarker to predict Progesterone-Resistant Endometrial Hyperplasia without atypia: A retrospective case-control study Open
Background/Aims: In our study, the effect of hyaluronan synthase 2 (HAS2) and CD44 immunoreactivity as a predictive biomarker in the prediction of progesterone-resistant endometrial hyperplasia (EH) cases without atypia was investigated. S…
View article: Enhanced Bone Healing Through Systemic Capsaicin Administration: An Experimental Study on Wistar Rats
Enhanced Bone Healing Through Systemic Capsaicin Administration: An Experimental Study on Wistar Rats Open
BACKGROUND The healing of bone defects is a serious challenge worldwide. One branch of dentistry deals with bone defects. Capsaicin has anti-inflammatory, anti-oxidative, and cholesterol-reducing effects. The aim of this study was to evalu…
View article: Investigation of Trpa1 and Trpc1 Immunreactivities in Colon Adenocarcinomas
Investigation of Trpa1 and Trpc1 Immunreactivities in Colon Adenocarcinomas Open
TRPA1 and TRPC1 immunoreactivites are increased in colorectal adenocarcinoma tissue compared with the healthy tissue. Furthermore, the immunoreactivity decreases as the grade of cancer increases.
View article: Enhanced Bone Healing Through Systemic Capsaicin Administration: An Experimental Study on Wistar Rats
Enhanced Bone Healing Through Systemic Capsaicin Administration: An Experimental Study on Wistar Rats Open
Background and Objectives: The healing of bone defects is a serious challenge worldwide. One branch of dentistry deals with bone defects. capsaicin has anti-inflammatory, anti-oxidative and cholesterol-reducing effects. The aim of this stu…
View article: The evaluation of cyclin D1 expression in prostate carcinoma cases
The evaluation of cyclin D1 expression in prostate carcinoma cases Open
Our results suggest the overexpression of CDDN1 is a potentially useful but poor prognostic biomarker for PCa cases.
View article: Do Histologically Aggressive Subtypes of Papillary Thyroid Microcarcinoma have Worse Clinical Outcome than Non-Aggressive Papillary Thyroid Microcarcinoma Subtypes? A Multicenter Cohort Study
Do Histologically Aggressive Subtypes of Papillary Thyroid Microcarcinoma have Worse Clinical Outcome than Non-Aggressive Papillary Thyroid Microcarcinoma Subtypes? A Multicenter Cohort Study Open
Histologically aggressive micropapillary thyroid carcinomas (PTMC) subtypes are thought to be associated with an aggressive clinical course. However, evidence for unfavorable clinical outcomes in patients with aggressive PTMC subtypes is n…
View article: Investigation of TRPM7 Immunoreactivity as a Biomarker to Predict Treatment-Resistant Endometrial Hyperplasia:A Retrospective Case-Control Study
Investigation of TRPM7 Immunoreactivity as a Biomarker to Predict Treatment-Resistant Endometrial Hyperplasia:A Retrospective Case-Control Study Open
ABS TRACT Objective: In our study, we investigated transient receptor potential melastatin 7 (TRPM7) immunoreactivity in pre- and posttreatment pathology samples of patients with endometrial hyperplasia (EH) who responded to progesterone t…
View article: Evaluation of the Effects of Dual Antiplatelet Therapy on Guided Bone Regeneration in Peri-Implant Bone Defect
Evaluation of the Effects of Dual Antiplatelet Therapy on Guided Bone Regeneration in Peri-Implant Bone Defect Open
In this study, the authors aim to investigate the effect of dual antiplatelet agents on peri-implant–guided bone regeneraation by studying a sample of rats with titanium implants in their tibias. The rats were randomly divided into 5 group…
View article: The overexpression of cyclin D1 is a positive prognostic factor in advanced-stage breast carcinoma cases
The overexpression of cyclin D1 is a positive prognostic factor in advanced-stage breast carcinoma cases Open
Our results suggest that CDDN1 expression can be used as a potentially appropriate positive prognostic biomarker for advanced-stage BC cases.
View article: Evaluation of the Effects of Topical Ellagic Acid and Graft Application on Bone Regeneration: an Experimental Study
Evaluation of the Effects of Topical Ellagic Acid and Graft Application on Bone Regeneration: an Experimental Study Open
Topical ellagic and graft applications show different effects at different doses under topical and systemic conditions. The dose amount of ellagic acid applied, especially in topical applications, has critical importance in bone healing.
View article: Fibulin1 and mesothelin expressions in pancreas ductal adenocarcinoma
Fibulin1 and mesothelin expressions in pancreas ductal adenocarcinoma Open
The FBLN1 expression, which is in the tumor microenvironment of PDCA, may serve as a prognostic biomarker.
View article: The effects of dual anti-platelet therapy on titanium implant osseointegration: an experimental study
The effects of dual anti-platelet therapy on titanium implant osseointegration: an experimental study Open
Aim: In this study, we aim to investigate the effect of dual anti-platelet agents on osseointegration by studying a sample of rats with titanium implants in their tibias. Material and Method: The titanium implants were placed surgically to…
View article: The effects of dual anti-platelet therapy on titanium implant osseointegration: an experimental study
The effects of dual anti-platelet therapy on titanium implant osseointegration: an experimental study Open
Aim: In this study, we aim to investigate the effect of dual anti-platelet agents on osseointegration by studying a sample of rats with titanium implants in their tibias. Material and Method: The titanium implants were placed surgically to…
View article: Research Article siRNA-mediated mesothelin silencing for treatment of mesothelioma
Research Article siRNA-mediated mesothelin silencing for treatment of mesothelioma Open
It is known that mesothelin (MSLN) is overexpressed in some cancers, and that it plays a role in cell growth through Wnt family member 1 protein.Malignant transformation usually occurs with disruption of autoregulation of autophagy-related…
View article: Prognostic Value of TRPM7 Expression and Factor XIIIa-Expressing Tumor-Associated Macrophages in Gastric Cancer
Prognostic Value of TRPM7 Expression and Factor XIIIa-Expressing Tumor-Associated Macrophages in Gastric Cancer Open
Purpose. TRPM7 is known to play a key role in tumor progression by regulating cellular proliferation, migration, and invasion in various cancer cell lines. However, there are no comprehensive clinical studies about the effect of TRPM7 expr…
View article: Effects of Systemic Propranolol Application on the New Bone Formation in Periimplant Guided Bone Regeneration
Effects of Systemic Propranolol Application on the New Bone Formation in Periimplant Guided Bone Regeneration Open
Within the limitations of this study, propranolol did not affect the new bone formation in peri-implant defects.
View article: Favourable effects of whey protein upon acetic acid-induced ulcerative colitis in rat model
Favourable effects of whey protein upon acetic acid-induced ulcerative colitis in rat model Open
Introduction In the context of the present study, we have aimed to examine the effects of the administration of whey protein through rectal enema to a acetic acid-induced ulcerative colitis in rats on the pathways of nuclear-related factor…
View article: The effect of caffeic acid phenethyl ester and Ankaferd Blood Stopper on the diabetic and nondiabetic gingival wound healing: an experimental study
The effect of caffeic acid phenethyl ester and Ankaferd Blood Stopper on the diabetic and nondiabetic gingival wound healing: an experimental study Open
ABS and CAPE have been found to have positive effects on gingival wound healing in the nondiabetic group. We think that this situation is caused by its antiinflammatory and antimicrobial properties.
View article: Effects of Carnosine, Ankaferd, and Silver Sulfadiazine on an Experimental Burn Model: Roles of Irisin and HSP70
Effects of Carnosine, Ankaferd, and Silver Sulfadiazine on an Experimental Burn Model: Roles of Irisin and HSP70 Open
In this study, the effects of carnosine, ankaferd, and 1% silver sulfadiazine applied topically on second-degree burns were investigated and the roles of irisin and Heat shock protein 70 (HSP70) in this healing process were evaluated. Nine…
View article: Decreased CDX2 Expression Adversely Effect On Prognosis Of Patients With Colorectal Cancer
Decreased CDX2 Expression Adversely Effect On Prognosis Of Patients With Colorectal Cancer Open
Objective: Since colorectal cancers (CRC) are tumors with heterogeneous biological behavior, prediction of their prognosis remains challenging. Caudal-related homeobox gene 2 (CDX2), which has important roles in the development and mainten…
View article: P2X7R as an independent prognostic indicator in gastric cancer
P2X7R as an independent prognostic indicator in gastric cancer Open
Gastric cancer is one of the foremost causes of cancer related death around the world. The P2X7 receptor (P2X7R), a member of the P2X receptor subfamily of P2 receptors, is a unique molecule that has been shown to affect tumor growth and p…
View article: Intratumoral Cytotoxic T-Lymphocyte Density and PD-L1 Expression Are Prognostic Biomarkers for Patients with Colorectal Cancer
Intratumoral Cytotoxic T-Lymphocyte Density and PD-L1 Expression Are Prognostic Biomarkers for Patients with Colorectal Cancer Open
Background and objectives: Cytotoxic T-lymphocyte (CTL)-mediated inflammatory response to tumors plays a crucial role in preventing the progression of some cancers. Programmed cell death ligand 1 (PD-L1), a cell-surface glycoprotein, has b…
View article: Tonsillar Kaposi Sarcoma in an HIV-Negative Patient: A Case Report
Tonsillar Kaposi Sarcoma in an HIV-Negative Patient: A Case Report Open
Kaposi’s sarcoma (KS) is a rare malignancy associated with AIDS and usually affects skin. The most common causative agent is the Human Herpes Virus Type 8 (HHV-8). In the literature, there are few case reports about KS with no association …