Eduardo Tamayo
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View article: Incidence and risk factors of postoperative delirium after surgery in the spanish population: The DELPO study
Incidence and risk factors of postoperative delirium after surgery in the spanish population: The DELPO study Open
This Spanish study found that postoperative delirium, linked to longer hospital stays and higher mortality, requires early detection and prevention to improve outcomes.
View article: Genome-wide association study of susceptibility to acute respiratory distress syndrome
Genome-wide association study of susceptibility to acute respiratory distress syndrome Open
View article: Circulating Extracellular Vesicle miR-150–5p as a biomarker for optimizing clinical management of sepsis and septic shock: A discovery and validation Study
Circulating Extracellular Vesicle miR-150–5p as a biomarker for optimizing clinical management of sepsis and septic shock: A discovery and validation Study Open
View article: Prevalence, Outcomes and Healthcare Costs of Postoperative ARDS Compared with Medical ARDS
Prevalence, Outcomes and Healthcare Costs of Postoperative ARDS Compared with Medical ARDS Open
Background/Objectives: Postoperative acute respiratory distress syndrome (ARDS) is a recognized complication with reported prevalence rates of up to 20% and highly variable mortality. However, there is limited published evidence comparing …
View article: A 15-year study of neuraminidase mutations and the increasing of S247N mutation in Spain
A 15-year study of neuraminidase mutations and the increasing of S247N mutation in Spain Open
The therapeutic arsenal against influenza is extremely limited and resistance often arises due to the emergence of mutations, especially in the neuraminidase (NA) gene. This study aimed to evaluate the evolution of NA mutations over 15 yea…
View article: High‐Dimensional Immunophenotyping of Post‐COVID‐19 and Post‐Influenza Patients Reveals Persistent and Specific Immune Signatures After Acute Respiratory Infection
High‐Dimensional Immunophenotyping of Post‐COVID‐19 and Post‐Influenza Patients Reveals Persistent and Specific Immune Signatures After Acute Respiratory Infection Open
Long‐term consequences of SARS‐CoV‐2 infection are unknown since recovered individuals can experience symptoms and latent viral reactivation for months. Indeed, acute post‐infection sequelae have also been observed in other respiratory vir…
View article: Nationwide analysis of COVID-19 complications, outcomes, and costs of childbirth in Spain
Nationwide analysis of COVID-19 complications, outcomes, and costs of childbirth in Spain Open
Introduction Pregnant women are considered a vulnerable group for COVID-19 with an increased risk for complications. The objective of this study is to describe in-hospital mortality, pregnancy outcomes, and direct hospital costs associated…
View article: Antimicrobial Dosing During Continuous Venovenous Hemodiafiltration in Septic Shock Patients: A Prospective, Multicenter Study Protocol
Antimicrobial Dosing During Continuous Venovenous Hemodiafiltration in Septic Shock Patients: A Prospective, Multicenter Study Protocol Open
Background: Sepsis is a major global health issue and the leading cause of death in critically ill patients, with rising incidence and associated healthcare costs. Early administration of antibiotic therapy is crucial, but increasing antib…
View article: Chest radiographs in acute respiratory distress syndrome: an Achilles' heel of the Berlin criteria?
Chest radiographs in acute respiratory distress syndrome: an Achilles' heel of the Berlin criteria? Open
Background Despite the high mortality and economic burden associated with the acute respiratory distress syndrome (ARDS), the role of chest radiograph (CXR) in ARDS diagnosis and prognosis remains uncertain. The purpose of this study is to…
View article: Study on the diagnostic role of exosome-derived miRNAs in postoperative septic shock and non-septic shock patients
Study on the diagnostic role of exosome-derived miRNAs in postoperative septic shock and non-septic shock patients Open
This study highlights extracellular vesicle-derived miRNAs as promising biomarkers for differentiating septic from non-septic shock. The identified three-miRNA signature has significant potential to enhance septic shock diagnosis, thereby …
View article: Epidemiological trends of mechanically ventilated acute respiratory distress syndrome in the twenty-first century: a nationwide, population-based retrospective study
Epidemiological trends of mechanically ventilated acute respiratory distress syndrome in the twenty-first century: a nationwide, population-based retrospective study Open
View article: Genome-wide association study of susceptibility to acute respiratory distress syndrome
Genome-wide association study of susceptibility to acute respiratory distress syndrome Open
Introduction Acute respiratory distress syndrome (ARDS) is a severe inflammatory process of the lung, often due to sepsis, and poses significant mortality burden in intensive care units. Here we conducted the largest genome-wide associatio…
View article: Disease burden of influenza in Spain: A five-season study (2015–2020)
Disease burden of influenza in Spain: A five-season study (2015–2020) Open
Influenza accounts for 30% of the total morbidity and mortality in the European Union. However, the specific burden in different European countries is largely unknown, and more research is needed to ascertain the reality of this disease. I…
View article: The Hidden Reality of Influenza Antiviral Resistance. A 15-Year Study of Neuraminidase Mutations and the Increasing of S247n Mutation in Spain
The Hidden Reality of Influenza Antiviral Resistance. A 15-Year Study of Neuraminidase Mutations and the Increasing of S247n Mutation in Spain Open
View article: Impact of Preoperative Anemia and Patient Blood Management Programs on Clinical Outcome: Multicenter Prospective Study Delpo-Anemia
Impact of Preoperative Anemia and Patient Blood Management Programs on Clinical Outcome: Multicenter Prospective Study Delpo-Anemia Open
View article: Managing Arrhythmias in Cardiogenic Shock: Insights Into Milrinone and Dobutamine Therapy
Managing Arrhythmias in Cardiogenic Shock: Insights Into Milrinone and Dobutamine Therapy Open
View article: Unbiased immunome characterisation correlates with COVID-19 mRNA vaccine failure in immunocompromised adults
Unbiased immunome characterisation correlates with COVID-19 mRNA vaccine failure in immunocompromised adults Open
Introduction Coronavirus disease 2019 (COVID-19) affects the population unequally, with a greater impact on older and immunosuppressed people. Methods Hence, we performed a prospective experimental cohort study to characterise the effect o…
View article: Development of a Risk Predictive Model for Erectile Dysfunction at 12 Months after COVID-19 Recovery: A Prospective Observational Study
Development of a Risk Predictive Model for Erectile Dysfunction at 12 Months after COVID-19 Recovery: A Prospective Observational Study Open
Objectives: To develop a risk prediction model for the identification of features involved in the prediction of erectile dysfunction (ED) at 12 months following COVID-19 recovery. Methods: We performed an observational prospective multicen…
View article: Development of a Risk Predictive Model for Erectile Dysfunction at 12 months after COVID-19 Recovery: A Prospective Observational Study
Development of a Risk Predictive Model for Erectile Dysfunction at 12 months after COVID-19 Recovery: A Prospective Observational Study Open
Objectives: To develop a risk prediction model for the identification of features involved in the prediction of erectile dysfunction (ED) at 12 months following COVID-19 recovery. Methods: We performed an observational prospective multicen…
View article: Value of the biomarker soluble tyrosine kinase 1 type fms (sFLT-1) in the diagnosis and prognosis of sepsis: a systematic review
Value of the biomarker soluble tyrosine kinase 1 type fms (sFLT-1) in the diagnosis and prognosis of sepsis: a systematic review Open
View article: A wide scope, pan-comparative, systematic meta-analysis of the efficacy of prophylactic strategies for cardiac surgery-associated acute kidney injury
A wide scope, pan-comparative, systematic meta-analysis of the efficacy of prophylactic strategies for cardiac surgery-associated acute kidney injury Open
Acute kidney injury (AKI) is the most common complication of cardiac surgery. Cardiac surgery-associated AKI (CSA-AKI) is caused by systemic and renal hemodynamic impairment and parenchymal injury. Prophylaxis of CSA-AKI remains an unmet p…
View article: Development of a Machine Learning-Based Model for the Prediction of Long-Term Erectile Dysfunction after COVID-19 Recovery: A Prospective Observational Study
Development of a Machine Learning-Based Model for the Prediction of Long-Term Erectile Dysfunction after COVID-19 Recovery: A Prospective Observational Study Open
Objectives: To develop a machine learning-based model for the identification of features involved in the prediction of long-term erectile dysfunction (ED) after COVID-19 recovery. Methods: We performed an observational prospective multicen…
View article: miRNome Profiling of Extracellular Vesicles in Patients With Severe COVID-19 and Identification of Predictors of Mortality
miRNome Profiling of Extracellular Vesicles in Patients With Severe COVID-19 and Identification of Predictors of Mortality Open
Background Extracellular vesicles (EVs), containing microRNAs (miRNAs) and other molecules, play a central role in intercellular communication, especially in viral infections caused by SARS-CoV-2. This study explores the miRNA profiles in …
View article: Valor del biomarcador tirosina quinasa 1 soluble tipo fms (sFLT-1) en el diagnóstico y pronóstico de la sepsis: una revisión sistemática
Valor del biomarcador tirosina quinasa 1 soluble tipo fms (sFLT-1) en el diagnóstico y pronóstico de la sepsis: una revisión sistemática Open
It is evident that sepsis is based on endothelial dysfunction. sFLT-1 is one of the main biomarkers of microvascular alteration and is a predictive diagnostic and prognostic biomarker.
View article: NEUROVASCULAR ANATOMY REVIEW IN THYROID AND PARATHYROID SURGERY. SURGICAL PROCEDURE TO MINIMIZE ADVERSE EVENTS
NEUROVASCULAR ANATOMY REVIEW IN THYROID AND PARATHYROID SURGERY. SURGICAL PROCEDURE TO MINIMIZE ADVERSE EVENTS Open
Introduction and objective: Recurrent laryngeal nerve (RLN) injury is the most important complication in thyroid surgery and its side effects vary from dysphonia in unilateral laryngeal paralysis to stridor in bilateral laryngeal paralysis…
View article: Uric acid and acute kidney injury in high-risk patients for developing acute kidney injury undergoing cardiac surgery: A prospective multicenter study
Uric acid and acute kidney injury in high-risk patients for developing acute kidney injury undergoing cardiac surgery: A prospective multicenter study Open
Hyperuricemia was not associated with an increased risk of AKI in this cohort of patients undergoing cardiac surgery at high risk of developing CSA-AKI.
View article: Abordajes quirúrgicos del espacio parafaríngeo. Comparación de abordajes externos y endoscópicos. Revisión sistemática
Abordajes quirúrgicos del espacio parafaríngeo. Comparación de abordajes externos y endoscópicos. Revisión sistemática Open
Introducción y objetivo: El espacio parafaríngeo es un espacio profundo cráneo-cervical donde los tumores primarios son excepcionales, constituyendo únicamente un 0,5% de todas las neoformaciones de cabeza y cuello. Las lesiones benignas r…
View article: COVID-19-associated pulmonary aspergillosis (CAPA) in hematological patients: Could antifungal prophylaxis be necessary? A nationwide study
COVID-19-associated pulmonary aspergillosis (CAPA) in hematological patients: Could antifungal prophylaxis be necessary? A nationwide study Open
COVID-19 constitutes an independent risk factor for developing aspergillosis in B-cell hematological malignancies and the use of antifungal prophylaxis during hospitalizations may be warranted.
View article: Dos tipos de neoformaciones del espacio parafaríngeo, dos ejemplos de abordajes (externo y endoscópico)
Dos tipos de neoformaciones del espacio parafaríngeo, dos ejemplos de abordajes (externo y endoscópico) Open
Introducción y objetivo: El espacio parafaríngeo es un espacio profundo de la cabeza y el cuello de importante dificultad anatómica. Aunque es una región donde se localizan únicamente un 0.5% de los tumores craneocervicales y la mayoría de…
View article: Post-operative sepsis-induced acute respiratory distress syndrome: risk factors for a life-threatening complication
Post-operative sepsis-induced acute respiratory distress syndrome: risk factors for a life-threatening complication Open
Introduction Prevalence and mortality of the acute respiratory distress syndrome (ARDS) in intensive care units (ICU) are unacceptably high. There is scarce literature on post-operative sepsis-induced ARDS despite that sepsis and major sur…