Gongshi Bai
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View article: HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability
HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability Open
View article: Author Correction: R-loop-derived cytoplasmic RNA–DNA hybrids activate an immune response
Author Correction: R-loop-derived cytoplasmic RNA–DNA hybrids activate an immune response Open
View article: HLTF Prevents G4 Accumulation and Promotes G4-induced Fork Slowing to Maintain Genome Stability
HLTF Prevents G4 Accumulation and Promotes G4-induced Fork Slowing to Maintain Genome Stability Open
Summary G-quadruplexes (G4s) form throughout the genome and influence important cellular processes, but their deregulation can challenge DNA replication fork progression and threaten genome stability. Here, we demonstrate an unexpected, du…
View article: R-loop-derived cytoplasmic RNA–DNA hybrids activate an immune response
R-loop-derived cytoplasmic RNA–DNA hybrids activate an immune response Open
View article: HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis
HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis Open
View article: Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent, microRNA-Assisted MCM2-7 Downregulation
Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent, microRNA-Assisted MCM2-7 Downregulation Open
Circumstances that compromise efficient DNA replication, such as disruptions to replication fork progression, cause a state known as DNA replication stress (RS). Whereas normally proliferating cells experience low levels of RS, excessive R…