Ayako Goto
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View article: Hoarding medication and suicide attempts with 1180 tablets of mirtazapine overdose: A case report
Hoarding medication and suicide attempts with 1180 tablets of mirtazapine overdose: A case report Open
Background Confirming a patient's consistent adherence to prescribed medication remains a persistent challenge for healthcare professionals. One reason for nonadherence is that patients accumulate their prescribed medicines with the intent…
View article: Effect of iron administration on the aortic iron content and vascular calcification in phosphorus-loaded chronic kidney disease rats
Effect of iron administration on the aortic iron content and vascular calcification in phosphorus-loaded chronic kidney disease rats Open
Background Cardiovascular disease (CVD) is a major cause of morbidity and mortality in patients with chronic kidney disease (CKD) and could be related to oxidative stress. Vascular calcification (VC) has been established as a critical risk…
View article: Adoption of inpatient family‐based treatment for anorexia nervosa: A case report
Adoption of inpatient family‐based treatment for anorexia nervosa: A case report Open
Background Family‐based treatment (FBT) is effective for the treatment of anorexia nervosa (AN) in children and adolescents. However, its availability in Japan is limited because it requires adherence to specific guidelines, commitment of …
View article: Associations Between Internet Addiction, Psychiatric Comorbidity, and Maternal Depression and Anxiety: Potential Underlying Mechanisms [Response to Letter]
Associations Between Internet Addiction, Psychiatric Comorbidity, and Maternal Depression and Anxiety: Potential Underlying Mechanisms [Response to Letter] Open
comments regarding our recent study highlighting the association between internet addiction (IA) in children and maternal depression and anxiety.We agree with the importance of exploring the possible factors involved in this association.Ou…
View article: Delayed recognition of autism spectrum disorder and attention-deficit/hyperactivity disorder in a girl with ornithine transcarbamylase deficiency: A case report
Delayed recognition of autism spectrum disorder and attention-deficit/hyperactivity disorder in a girl with ornithine transcarbamylase deficiency: A case report Open
Rationale: Ornithine transcarbamylase (OTC) deficiency, a urea cycle disorder, is a rare congenital metabolic error that leads to hyperammonemia. Psychiatric symptoms of hyperammonemia are nonspecific and can cause autism spectrum disorder…
View article: Associations between Internet Addiction, Psychiatric Comorbidity, and Maternal Depression and Anxiety in Clinically Referred Children and Adolescents
Associations between Internet Addiction, Psychiatric Comorbidity, and Maternal Depression and Anxiety in Clinically Referred Children and Adolescents Open
Maternal depression and anxiety may be one of the risk factors for children and adolescents to develop IA. Care for maternal depression and anxiety may contribute to intervention for children and adolescents with IA.
View article: Associations Between Chronic Irritability and Sensory Processing Difficulties in Children and Adolescents
Associations Between Chronic Irritability and Sensory Processing Difficulties in Children and Adolescents Open
Irritability is one of the most common reasons for which children and adolescents are referred for psychiatric evaluation and care. However, clinical irritability is difficult to define; thus, its prevalence varies widely. Chronic irritabi…
View article: COVID-19 phobia in a boy with undiagnosed autism spectrum disorder
COVID-19 phobia in a boy with undiagnosed autism spectrum disorder Open
Rationale: Coronavirus disease 2019 (COVID-19) is affecting mental health profoundly. Previous studies have reported pandemic-related anxiety. Anxiety disorder and autism spectrum disorder (ASD) are common comorbidities. However, there has…
View article: COVID-19 phobia in a boy with undiagnosed autism spectrum disorder: a case report
COVID-19 phobia in a boy with undiagnosed autism spectrum disorder: a case report Open
BackgroundThe coronavirus disease (COVID-19) is affecting mental health profoundly. Previous studies have reported pandemic-related anxiety. Anxiety disorder and autism spectrum disorder (ASD) are relatively common comorbidities. However, …
View article: Total RNA and genomic DNA of Lactobacillus gasseri OLL2809 induce interleukin-12 production in the mouse macrophage cell line J774.1 via toll-like receptors 7 and 9
Total RNA and genomic DNA of Lactobacillus gasseri OLL2809 induce interleukin-12 production in the mouse macrophage cell line J774.1 via toll-like receptors 7 and 9 Open
Background Lactobacillus gasseri OLL2809 can highly induce interleukin (IL)-12 production in immune cells. Even though beneficial properties of this strain for both humans and animals have been reported, the mechanism by which the bacteria…
View article: Additional file 1 of Total RNA and genomic DNA of Lactobacillus gasseri OLL2809 induce interleukin-12 production in the mouse macrophage cell line J774.1 via toll-like receptors 7 and 9
Additional file 1 of Total RNA and genomic DNA of Lactobacillus gasseri OLL2809 induce interleukin-12 production in the mouse macrophage cell line J774.1 via toll-like receptors 7 and 9 Open
Additional file 1: Figure A1. Effects of cytochalasin D treatment on viability of J774.1 cells (a) and IL-12 production stimulated with Pam3CSK4. Figure A2. Viability of J774.1 cells during MYD88 inhibition assay. Figure A3. Viability of J…
View article: Mucosal incision‐assisted biopsy versus endoscopic ultrasound‐guided fine‐needle aspiration with a rapid on‐site evaluation for gastric subepithelial lesions: A randomized cross‐over study
Mucosal incision‐assisted biopsy versus endoscopic ultrasound‐guided fine‐needle aspiration with a rapid on‐site evaluation for gastric subepithelial lesions: A randomized cross‐over study Open
Objectives This study aimed to compare the diagnostic yield of mucosal incision‐assisted biopsy ( MIAB ) and endoscopic ultrasound‐guided fine‐needle aspiration ( EUS ‐ FNA ) with a rapid on‐site evaluation ( ROSE ) for gastric subepitheli…
View article: Preschool-onset obsessive-compulsive disorder with complete remission
Preschool-onset obsessive-compulsive disorder with complete remission Open
Early-onset obsessive-compulsive disorder (OCD) is more severe than later-onset OCD. There are no reports of any early-onset OCD patients being cured, especially with respect to preschoolers. In this case report, we describe the successful…
View article: EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells
EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells Open
The highly conserved Rab guanosine triphosphatase (GTPase) Rab8 plays a role in exocytosis toward the polarized plasma membrane in eukaryotic cells. In murine Rab8-deficient small intestine cells, apical proteins are missorted into lysosom…
View article: Psychogenic nonepileptic seizures as a manifestation of psychological distress associated with undiagnosed autism spectrum disorder
Psychogenic nonepileptic seizures as a manifestation of psychological distress associated with undiagnosed autism spectrum disorder Open
Psychogenic nonepileptic seizures (PNES) are observable changes in behavior or consciousness that are similar to epileptic seizures but are not associated with electrophysiologic changes. PNES occur in children with underlying psychologica…
View article: Enhanced natural killer cell activation by exopolysaccharides derived from yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1
Enhanced natural killer cell activation by exopolysaccharides derived from yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 Open
Yogurt is generally recognized as a beneficial food for our health, but research into its physiological effects has focused mainly on intestinal dysfunctions such as constipation and diarrhea. We previously found yogurt fermented with Lact…