D V Gowda
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View article: Discovering Novel Short‐ and Medium‐Chain Esters of Hydroxy Fatty Acids in Human Fecal Samples Using Untargeted Liquid Chromatography/Mass Spectrometry
Discovering Novel Short‐ and Medium‐Chain Esters of Hydroxy Fatty Acids in Human Fecal Samples Using Untargeted Liquid Chromatography/Mass Spectrometry Open
Rationale Exploring novel metabolites produced by host gut microbiome communication is crucial for understanding their roles in various disease pathologies. We previously uncovered a novel class of lipids, short‐chain fatty acid esters of …
View article: Pulmonary Targeting of Inhalable Moxifloxacin Microspheres for Effective Management of Tuberculosis
Pulmonary Targeting of Inhalable Moxifloxacin Microspheres for Effective Management of Tuberculosis Open
In the present study, the objective was to attain a localized lung delivery of an anti-tubercular fluoroquinolone, moxifloxacin (MXF), targeting the alveolar macrophages through a non-invasive pulmonary route using inhalable microspheres a…
View article: A Review on Insulin Formulations for Diabetes Mellitus Therapy
A Review on Insulin Formulations for Diabetes Mellitus Therapy Open
The insulin discovery during the past century is considered as the major breakout in the health sector. It is considered as lifesaving medication for T1DM and T2DM. In the advancement of peptide chemistry, pharmacology, cell signalling and…
View article: Recent developments in orally disintegrating mini tablets
Recent developments in orally disintegrating mini tablets Open
Solid oral dosage forms are most suitable dosage forms; preferably tablets are widely accepted by people of different age groups. Mini tablets are tablets with a diameter equal to or smaller than 2–3 mm. Mini tablets are multiple unit dosa…
View article: Triple-negative breast cancer: challenges and treatment options
Triple-negative breast cancer: challenges and treatment options Open
TNBCs or Triple negative breast cancers are characterized by the deficiency of progesterone and estrogen receptors and also the absence down regulation of Human epithelial growth receptor type 2 (HER2). TNBCs have low prognosis rate becaus…
View article: Therapeutic application of Resveratrol in human diseases
Therapeutic application of Resveratrol in human diseases Open
Resveratrol (3,4,5-trihydroxystilbene) is a member of natural and plant-derived chemicals, which is known as polyphenols and it is getting more consideration because of its various health assistances. Largely in the case of neurological pr…
View article: Alcoholic liver diseases: Disease spectrum, pathophysiology, oxidative stress and role of flavonoids in alcoholic liver injury
Alcoholic liver diseases: Disease spectrum, pathophysiology, oxidative stress and role of flavonoids in alcoholic liver injury Open
An Alcoholic Liver Disease (ALD) has emerged as the serious health problem globally, with high morbidity and mortality rate. Heavy alcohol consumption resulted in broad spectrum of liver diseases ranging from steatosis (alcoholic fatty liv…
View article: Mitochondrial Drug Delivery for the Liver Diseases: Comprehensive Review
Mitochondrial Drug Delivery for the Liver Diseases: Comprehensive Review Open
The role of mitochondria in liver targeting has been reviewed, which mainly focuses on acute and chronic. This is due to ethanol consumption, which causes liver damage. And how ethanol consumption affects liver disease. Autophagy, which ex…
View article: A Review on Candidiasis resistance current drug development process in its prevention and treatment
A Review on Candidiasis resistance current drug development process in its prevention and treatment Open
A fungal infection caused by Candida albicans leads to illness and death worldwide. This review mainly focused upon Vulvovaginal Candidiasis that is a common fungal infection seen in women, especially during pregnancy; Candida species caus…
View article: A Comprehensive review on Dendrimers in current advanced Drug delivery
A Comprehensive review on Dendrimers in current advanced Drug delivery Open
In this particular review, it is been noted that Dendrimers are novel three-dimensional globular nano-polymeric structure; having multiple functional groups on the surface enhances their function. Synonymous terms for dendrimer include arb…
View article: Recent Development in Sustained Release Beads
Recent Development in Sustained Release Beads Open
The sustained release system is formulated to release a drug slowly over a period of time in the body. The sustained release system is having more therapeutic activity of a drug when compared to immediate release. Beads is one of the most …
View article: An overview on topical drug delivery system – Updated review
An overview on topical drug delivery system – Updated review Open
The paper reviews an overview of a conventional and novel approach in the topical drug delivery system. Drug delivery via the skin is becoming progressively popular due to its convenience and affordability. The skin is the most important m…
View article: The insights on Oro-dispersible tablet
The insights on Oro-dispersible tablet Open
Orodispersible tablets (ODTs) were the conventional product that disintegrates or dissolves into the buccal mucosa in less than 1mins in the absence of water and without chewing. They were first acquainted with the market during the 1980s,…
View article: Pilot plant scale up for tablet
Pilot plant scale up for tablet Open
The manufacture of oral dosage forms is a complex process in which the starting material of API is converted into the final product by the manufacturing and processing into different physical properties in order to produce the final produc…
View article: Development of biodegradable scaffolds loaded with vancomycin micropartricles for the treatment of osteomyelitis
Development of biodegradable scaffolds loaded with vancomycin micropartricles for the treatment of osteomyelitis Open
In this present research work, the development of biodegradable scaffolds loaded with Vancomycin micropartricles was carried out for the treatment of Osteomyelitis. Characterization Vancomycin Loaded microparticles and evaluation of the mi…
View article: Enteric Delivery of Diclofenac Sodium through Functionally Modified Poly(acrylamide-grafted-Ghatti gum)-based pH-sensitive Hydrogel Beads: Development, Formulation and Evaluation
Enteric Delivery of Diclofenac Sodium through Functionally Modified Poly(acrylamide-grafted-Ghatti gum)-based pH-sensitive Hydrogel Beads: Development, Formulation and Evaluation Open
: Background: To prepare and characterize modified Poly(acrylamide-grafted- Ghatti gum). To formulate and evaluate using this grafted polymer pH-sensitive hydrogel beads of diclofenac sodium for enteric delivery. Methods: Polyacrylamide wa…