Gowhar Rashid
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View article: Epidemiological and clinicopathological characteristics of ovarian cancer in Syria during the war years: a national multicenter retrospective study (2017–2021)
Epidemiological and clinicopathological characteristics of ovarian cancer in Syria during the war years: a national multicenter retrospective study (2017–2021) Open
Our study revealed a lower proportion of OCs diagnoses among all cancer cases compared to global and regional data which may be attributed to underreporting, influenced by the disease's specific characteristics and presence of more barrier…
View article: Discovery of drug transporter inhibitors tied to long noncoding RNA in resistant cancer cells; a computational model -in silico- study
Discovery of drug transporter inhibitors tied to long noncoding RNA in resistant cancer cells; a computational model -in silico- study Open
Chemotherapeutic resistance is a major obstacle to chemotherapeutic failure. Cancer cell resistance involves several mechanisms, including epithelial-to-mesenchymal transition (EMT), signaling pathway bypass, drug efflux activation, and im…
View article: Genetic Mutations and Inherited Syndromes
Genetic Mutations and Inherited Syndromes Open
View article: Spatiotemporal variation in fish species distribution and abundance in the Vaishav stream, Kashmir Himalaya–India
Spatiotemporal variation in fish species distribution and abundance in the Vaishav stream, Kashmir Himalaya–India Open
Exploring the intricate dynamics of aquatic ecosystems present study investigates the spatio-temporal variations in the ecological parameters of the fish community within the Vaishav stream, Kashmir Himalayas. Monthly field investigations …
View article: Effectiveness of postoperative cephalosporins in reducing urinary tract infections and other parameters following transurethral resection of the prostate: a systematic review and meta-analysis
Effectiveness of postoperative cephalosporins in reducing urinary tract infections and other parameters following transurethral resection of the prostate: a systematic review and meta-analysis Open
View article: RETRACTED ARTICLE: Prevalence and knowledge of polycystic ovary syndrome (PCOS) and health-related practices among women of Syria: a cross-sectional study
RETRACTED ARTICLE: Prevalence and knowledge of polycystic ovary syndrome (PCOS) and health-related practices among women of Syria: a cross-sectional study Open
Polycystic Ovarian Syndrome (PCOS) is a prevalent metabolic and hormonal disorder affecting women of reproductive age. Limited data exists on Syrian women's PCOS awareness and health behaviors. This study aimed to gauge PCOS prevalence, kn…
View article: Vitamin D deficiency and the vitamin D receptor (VDR) gene polymorphism rs2228570 (FokI) are associated with an increased susceptibility to hypertension among the Bangladeshi population
Vitamin D deficiency and the vitamin D receptor (VDR) gene polymorphism rs2228570 (FokI) are associated with an increased susceptibility to hypertension among the Bangladeshi population Open
Vitamin D receptor (VDR) gene is implicated in hypertension vulnerability due to its role in regulating the renin-angiotensin system (RAS) and blood pressure. In this case-control study, a carefully selected cohort of 111 hypertensive indi…
View article: Awareness of lung cancer risk factors and symptoms in Syria: an online cross-sectional study
Awareness of lung cancer risk factors and symptoms in Syria: an online cross-sectional study Open
Background Globally, lung cancer is the leading cause of cancer fatalities and the second most frequent cancer. Population knowledge of the features of lung cancer is a crucial strategy for early diagnosis and decreasing the mortality rate…
View article: Gene-environment interactions and colorectal cancer risk: A case-control study on xenobiotic metabolizing enzyme polymorphisms in the Jammu& Kashmir, India population
Gene-environment interactions and colorectal cancer risk: A case-control study on xenobiotic metabolizing enzyme polymorphisms in the Jammu& Kashmir, India population Open
Background: Cancer remains a significant global health concern, with colorectal cancer (CRC) showing a rising incidence, particularly among younger populations. Most CRC cases are linked to a complex interplay of genetic and environmental …
View article: Exploring the role of miR-361-3p in gastric cancer therapeutics and tumor progression
Exploring the role of miR-361-3p in gastric cancer therapeutics and tumor progression Open
View article: Hypomethylation of Sonic hedgehog in colorectal cancer
Hypomethylation of Sonic hedgehog in colorectal cancer Open
Background: Past research has demonstrated that a changed Sonic Hedgehog (SHH) pattern contributes to the development of colorectal cancer. This study’s objective was to determine whether the SHH gene’s promoter hypomethylation might be us…
View article: Emerging tendencies for the nano-delivery of gambogic acid: a promising approach in oncotherapy
Emerging tendencies for the nano-delivery of gambogic acid: a promising approach in oncotherapy Open
Despite the advancements in cancer therapies during the past few years, chemo/photo resistance, severe toxic effects, recurrence of metastatic tumors, and non-selective targeting remain incomprehensible.
View article: Pharmacogenomic and epigenomic approaches to untangle the enigma of IL-10 blockade in oncology
Pharmacogenomic and epigenomic approaches to untangle the enigma of IL-10 blockade in oncology Open
The host immune system status remains an unresolved mystery among several malignancies. An immune-compromised state or smart immune-surveillance tactics orchestrated by cancer cells are the primary cause of cancer invasion and metastasis. …
View article: ABO and Rhesus blood group markers as predictors in colorectal cancer: A prospective observational study
ABO and Rhesus blood group markers as predictors in colorectal cancer: A prospective observational study Open
Numerous research studies have investigated the relationship between ABO and Rhesus (Rh) blood groups and the risk of various cancers, yielding diverse findings. While these blood groups have been established as prognostic factors in some …
View article: Unraveling the relationship between the renin–angiotensin system and endometrial cancer: a comprehensive review
Unraveling the relationship between the renin–angiotensin system and endometrial cancer: a comprehensive review Open
Endometrial cancer (EC), the most common adenocarcinoma, represents 90% of uterine cancer in women with an increased incidence of occurrence attributed to age, obesity, hypertension, and hypoestrogenism. Being the most common gynecological…
View article: Nanotube breakthroughs: unveiling the potential of carbon nanotubes as a dual therapeutic arsenal for Alzheimer’s disease and brain tumors
Nanotube breakthroughs: unveiling the potential of carbon nanotubes as a dual therapeutic arsenal for Alzheimer’s disease and brain tumors Open
Alzheimer’s disease (AD) and brain tumors are debilitating neurological conditions that pose significant challenges in current medical practices. Existing treatment options for AD primarily focus on symptom management, and brain tumors oft…
View article: Anterior Nutcracker syndrome in a young male patient: a case report and review of literature
Anterior Nutcracker syndrome in a young male patient: a case report and review of literature Open
Introduction and importance: The left renal vein (LRV) is affected by a venous compression syndrome called Nutcracker syndrome (NCS). This syndrome is characterized by extrinsic compression of the LRV, which usually occurs between aorta an…
View article: Knowledge toward ovarian cancer symptoms among women in Syria: Cross-sectional study
Knowledge toward ovarian cancer symptoms among women in Syria: Cross-sectional study Open
View article: Pathogenicity of the entomopathogenic fungi against Myllocerus fotedari Ahmad, 1974 (Coleoptera: Curculionidae) under laboratory conditions in India
Pathogenicity of the entomopathogenic fungi against Myllocerus fotedari Ahmad, 1974 (Coleoptera: Curculionidae) under laboratory conditions in India Open
The weevil, Myllocerus fotedari Ahmad, 1974 (Coleoptera: Curculionidae) is widely recognised as one of the major walnut pests. Fungal pathogens have shown great potential for the management of some pest species. In the present study, the e…
View article: Association of NPHS2, PON1 and KCNJ11 Gene Polymorphisms with Diabetic Nephropathy
Association of NPHS2, PON1 and KCNJ11 Gene Polymorphisms with Diabetic Nephropathy Open
Purpose: Diabetic nephropathy (DN) affects almost 40% of diabetic patients and is clinically categorized by declining glomerular filtration rate, proteinuria and hypertension, ultimately leads to renal failure. Genome-wide association stud…
View article: Assessment the Awareness of the Syrian Population toward the Risk Factors and Symptoms of Colorectal Cancer: Cross Sectional Study
Assessment the Awareness of the Syrian Population toward the Risk Factors and Symptoms of Colorectal Cancer: Cross Sectional Study Open
Background This cross-sectional research seeks to examine the level of knowledge of CRC risk factors and symptoms in Syria. Methods An online cross-sectional study was conducted from 1 August to 25 August 2022. The sample inclusion criteri…
View article: Non-steroidal anti-inflammatory drugs and biomarkers: A new paradigm in colorectal cancer
Non-steroidal anti-inflammatory drugs and biomarkers: A new paradigm in colorectal cancer Open
Colorectal cancer is a sporadic, hereditary, or familial based disease in its origin, caused due to diverse set of mutations in large intestinal epithelial cells. Colorectal cancer (CRC) is a common and deadly disease that accounts for the…
View article: Colorectal Cancer (CRC): Investigating the Expression of the Suppressor of Fused (SuFu) Gene and Its Relationship with Several Inflammatory Blood-Based Biomarkers
Colorectal Cancer (CRC): Investigating the Expression of the Suppressor of Fused (SuFu) Gene and Its Relationship with Several Inflammatory Blood-Based Biomarkers Open
Background: Suppressor of fused (SuFu) is a tumor-suppressor gene that regulates hedgehog signaling. Its involvement in some malignancies is broadly accepted. However, its association with colorectal cancer (CRC) pathogenesis is not clear.…
View article: Assessing Syrian women's knowledge of breast cancer risk factors, warning signs, and barriers to preventive measures: A cross-sectional study
Assessing Syrian women's knowledge of breast cancer risk factors, warning signs, and barriers to preventive measures: A cross-sectional study Open
View article: The Prognostic Value of Abo and Rhesus Blood Groups in Patients with Colorectal Cancer: A Prospective Observational Study
The Prognostic Value of Abo and Rhesus Blood Groups in Patients with Colorectal Cancer: A Prospective Observational Study Open
View article: Correction to: Evaluation of Forkhead BOX M1 (FOXM1) gene expression in colorectal cancer
Correction to: Evaluation of Forkhead BOX M1 (FOXM1) gene expression in colorectal cancer Open
View article: ADA Levels in Body Fluids as the Preferred Test to Rule Out Tuberculosis in Limited-resource Settings: Data from a Tertiary Care Hospital in Northern India
ADA Levels in Body Fluids as the Preferred Test to Rule Out Tuberculosis in Limited-resource Settings: Data from a Tertiary Care Hospital in Northern India Open
In clinical practice, the diagnosis of tuberculosis (TB) continues to be a challenge. The goal of this study was to evaluate the reliability and impact of adenosine deaminase (ADA) enzyme testing as a biochemical marker in the continued ma…
View article: Association of -675 4G/5G PAI-1 and -2518A/G MCP-1 genetic polymorphisms with polycystic ovary syndrome in Kashmiri women: A case control study
Association of -675 4G/5G PAI-1 and -2518A/G MCP-1 genetic polymorphisms with polycystic ovary syndrome in Kashmiri women: A case control study Open
Background: Polycystic ovarian syndrome (PCOS) is a highly prevalent endocrine disorder among females of fertile age. It has been speculated to be associated with low-grade chronic inflammation like other inflammatory response-driven multi…
View article: Connective tissue growth factor expression hints at aggressive nature of colorectal cancer
Connective tissue growth factor expression hints at aggressive nature of colorectal cancer Open
Expression of CTGF was increased in CRC and was linked with poor overall and disease-free survival of CRC patients. These findings support prior observations and thus CTGF may be a possible prognostic marker in CRC.
View article: Serum Liver Enzyme Levels: A Hospital-Based Observational Study from Kashmir
Serum Liver Enzyme Levels: A Hospital-Based Observational Study from Kashmir Open
Background: Liver disorders are one of the most common causes of health problems all over the world owing to evolving lifestyles and dietary patterns. In this retrospective study, we aimed to explore the impact of dietary habits on liver e…