Explanipedia

[Analysis of the misdiagnosis causes and treatment strategies for burns combined with alcohol withdrawal syndrome]. Open

訓子村上, Mingxia Ding, Grace A. Lin, Chuanyue Wang, Z C Lin , et al. · 2025

Objective: To investigate the misdiagnosis causes and treatment strategies for burns combined with alcohol withdrawal syndrome (AWS). Methods: This study was a retrospective observational study. From January 2014 to December …

Alzheimer's disease blood-based biomarker testing: A stakeholder-informed assessment of coverage considerations Open

Patricia A. Deverka, Jalayne J. Arias, Grace A. Lin, Jessica Zwerling, Kathryn A. Phillips · 2025

Background Recently published clinical studies suggest that blood-based biomarker tests (BBMTs) for Alzheimer's disease (AD) provide value, but in the U.S., neither public nor private payers currently cover these tests. Objective To descri…

The effectiveness and value of ensifentrine for the treatment of chronic obstructive pulmonary disease Open

Abigail C. Wright, Grace A. Lin, Melanie D. Whittington, Avery McKenna, Finn Raymond , et al. · 2024

Payer Coverage Considerations for Alzheimer Disease Blood-Based Biomarker Tests Open

Patricia A. Deverka, Grace A. Lin, Kathryn A. Phillips · 2024

This Viewpoint discusses proactively preparing to make informed payer coverage decisions to help address current disparities in Alzheimer disease diagnosis and treatment.

Impact of a patient-centered tool to reduce misconceptions about coronary artery disease and its treatment: The CAD roadmap Open

Laura D. Scherer, Grace A. Lin, Vinay Kini · 2024

Unlike many other interventions, the CAD Roadmap is specifically designed to overcome common misconceptions to improve health behaviors.

The State of State Biomarker Testing Insurance Coverage Laws Open

Grace A. Lin, Janet M. Coffman, Kathryn A. Phillips · 2024

This Viewpoint discusses laws mandating insurance coverage of biomarker testing to broaden access to care for patients with cancer.

The effectiveness and value of sotatercept for pulmonary arterial hypertension: A summary from the Institute for Clinical and Economic Review’s Midwest Comparative Effectiveness Public Advisory Council Open

Dmitriy Nikitin, Grace A. Lin, Melanie D. Whittington, Emily Nhan, Yasmine Kayali , et al. · 2024

Modelling interventions and contact networks to reduce the spread of carbapenem-resistant organisms between individuals in the ICU Open

Deirdre Martinez, J. Cai, Grace A. Lin, Katherine E Goodman, Rajib Paul , et al. · 2024

Background: Contact precautions are widely used to prevent the transmission of carbapenem-resistant organisms (CROs) in hospital wards. However, evidence for their effectiveness in natural hospital environments is limited. Objective: To de…

Atidarsagene autotemcel for metachromatic leukodystrophy Open

Shahariar Mohammed Fahim, Grace A. Lin, Kangho Suh, Josh J. Carlson, Marina Richardson , et al. · 2024

The effectiveness and value of lecanemab for early Alzheimer disease: A summary from the Institute for Clinical and Economic Review’s California Technology Assessment Forum Open

Abigail C. Wright, Grace A. Lin, Melanie D. Whittington, Foluso Agboola, Serina Herron-Smith , et al. · 2023

Reading the crystal ball: Primary care implications while awaiting outcomes for multi-cancer early detection tests Open

Grace A. Lin, Kathryn A. Phillips, A. Mark Fendrick · 2023

Oral and monoclonal antibody treatments for relapsing forms of multiple sclerosis: Effectiveness and value Open

Avery McKenna, Grace A. Lin, Melanie D. Whittington, Dmitriy Nikitin, Serina Herron-Smith , et al. · 2023

DISCLOSURES: Ms McKenna, Dr Lin, Dr Whittington, Mr Nikitin, Ms Herron-Smith, Dr Campbell, and Dr Peterson report grants from Arnold Ventures, grants from Blue Cross Blue Shield of MA, grants from California Healthcare Foundation, g…

The effectiveness and value of fezolinetant for moderate-to-severe vasomotor symptoms associated with menopause: A summary from the Institute for Clinical and Economic Review’s Midwest Public Advisory Council Open

Abigail C. Wright, Francesca L. Beaudoin, Robert B. McQueen, Kai Yeung, Ashton Moradi , et al. · 2023

Association of Device Industry Payments, Physician Supply, and Regional Utilization of Orthopedic and Cardiac Procedures Open

Sruthi Muluk, Grace A. Lin, Timothy S. Anderson · 2023

Modelling interventions and contact networks to reduce the spread of carbapenem-resistant organisms between individuals in the ICU Open

Deirdre Martinez, J. Cai, Grace A. Lin, Katherine E Goodman, Rajib Paul , et al. · 2023

Correction Open

Martha Grogan, Francisco Lopez- Jimenez, Michal Cohen-Shelly Bsc, Angela Dispenzieri, Zachi I. Attia , et al. · 2022

Geriatricians’ Perspectives on the Multiple Dimensions of Utility of Genetic Testing for Alzheimer’s Disease: A Qualitative Study Open

Jalayne J. Arias, Grace A. Lin, Ana Tyler, Michael P. Douglas, Kathryn A. Phillips · 2022

Background: Research advancements in Alzheimer’s disease (AD) raise opportunities for genetic testing to improve diagnostic and risk assessment. Despite emerging developments, it is unclear how geriatricians perceive the potential clinical…

The effectiveness and value of tirzepatide for type 2 diabetes mellitus Open

Dmitriy Nikitin, Grace A. Lin, Jon D Campbell, Ryan N. Hansen, Elizabeth Brouwer , et al. · 2022

Terminology and descriptions of navigation and related practices for children with neurodisability and their families: a scoping review Open

Emily Gardiner, Vivian Wong, Grace A. Lin, Anton R. Miller · 2022

Background Children with neurodisability (ND) represent a significant population with a demonstrated need for coordinated support. Patient navigation has a primary focus on: facilitating access to and connection amongst fragmented systems;…

Hereditary cancer panel testing challenges and solutions for the latinx community: costs, access, and variants Open

Michael P. Douglas, Grace A. Lin, Julia R. Trosman, Kathryn A. Phillips · 2021

The effectiveness and value of aducanumab for Alzheimer’s disease Open

Patricia G. Synnott, Melanie D. Whittington, Grace A. Lin, David M. Rind, Steven D. Pearson · 2021

DISCLOSURES: Funding for this summary was contributed by Arnold Ventures, The Donaghue Foundation, Harvard Pilgrim Health Care, and Kaiser Foundation Health Plan to the Institute for Clinical and Economic Review (ICER), an independe…

Influence of payer coverage and out‐of‐pocket costs on ordering of NGS panel tests for hereditary cancer in diverse settings Open

Grace A. Lin, Julia R. Trosman, Michael P. Douglas, Christine B. Weldon, Maren T. Scheuner , et al. · 2021

The landscape of payment for genetic testing has been changing, with an increase in the number of laboratories offering testing, larger panel offerings, and lower prices. To determine the influence of payer coverage and out‐of‐pocket costs…

The effectiveness and value of bempedoic acid and inclisiran for heterozygous familial hypercholesterolemia and secondary prevention of ASCVD Open

Foluso Agboola, Grace A. Lin, Dhruv S. Kazi, Avery McKenna, Steven D. Pearson · 2021

DISCLOSURES: Funding for this summary was contributed by Arnold Ventures, California Health Care Foundation, The Donaghue Foundation, Harvard Pilgrim Health Care, and Kaiser Foundation Health Plan to the Institute for Clinical and E…

Patient Roadmaps for Chronic Illness: Introducing a New Approach for Fostering Patient-Centered Care Open

Laura D. Scherer, Daniel D. Matlock, Larry A. Allen, Christopher E. Knoepke, Colleen K. McIlvennan , et al. · 2021

Background. Too frequently, patients with chronic illnesses are surprised by disease-related changes and are unprepared to make decisions based on their values. Many patients are not activated and do not see a role for themselves in decisi…

Is Better Patient Knowledge Associated with Different Treatment Preferences? A Survey of Patients with Stable Coronary Artery Disease Open

Neal Yuan, Christy Boscardin, Nadra E. Lisha, R. Adams Dudley, Grace A. Lin · 2021

While communicating the risks of PCI may improve patient knowledge, this knowledge may not affect patient treatment preferences. Rather, other factors such as race may be significantly more influential on a patient's treatment preferences.…

The Effectiveness and Value of Deflazacort and Exon-Skipping Therapies for the Management of Duchenne Muscular Dystrophy Open

Foluso Agboola, Grace A. Lin, Noemi Fluetsch, Surrey M. Walton, David M. Rind , et al. · 2020

Funding for this summary was contributed by Arnold Ventures, Commonwealth Fund, California Health Care Foundation, National Institute for Health Care Management (NIHCM), New England States Consortium Systems Organization, Blue Cross Blue S…

Association of Primary Language and Hospitalization for Ambulatory Care Sensitive Conditions Open

Timothy S. Anderson, Leah Karliner, Grace A. Lin · 2019

Background: Limited English proficiency is associated with decreased access to ambulatory care, however, it is unclear if this disparity leads to increased use of emergency departments (EDs) for low severity ambulatory care sensitive condi…

Electronic health records systems and hospital clinical performance: a study of nationwide hospital data Open

Neal Yuan, R. Adams Dudley, W. John Boscardin, Grace A. Lin · 2019

Objective Electronic health records (EHRs) were expected to yield numerous benefits. However, early studies found mixed evidence of this. We sought to determine whether widespread adoption of modern EHRs in the US has improved clinical car…

The Effectiveness and Value of Lanadelumab and C1 Esterase Inhibitors for Prophylaxis of Hereditary Angioedema Attacks Open

Foluso Agboola, Solomon J. Lubinga, Josh J. Carlson, Grace A. Lin, William B Dreitlein , et al. · 2019

Funding for this summary was contributed by the Laura and John Arnold Foundation, Blue Shield of California, and California Health Care Foundation to the Institute for Clinical and Economic Review (ICER), an independent organization that e…

Out-of-Pocket Costs for Infliximab and Its Biosimilar for Rheumatoid Arthritis Under Medicare Part D Open

Jinoos Yazdany, R. Adams Dudley, Grace A. Lin, Randi Chen, Chien‐Wen Tseng · 2018

This study estimates mean 2017 total and out-of-pocket costs for infliximab and its biosimilar infliximab-dyyb under Medicare Part D.

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