Graeme MacLennan
YOU?
Author Swipe
View article: Ward AdmiSsion of Haematuria, an Observational mUlticentre sTudy: patient-level analysis (WASHOUT)
Ward AdmiSsion of Haematuria, an Observational mUlticentre sTudy: patient-level analysis (WASHOUT) Open
View article: Spirometry to manage asthma in children: study protocol for a randomised controlled trial (SPIROMAC)
Spirometry to manage asthma in children: study protocol for a randomised controlled trial (SPIROMAC) Open
View article: ColoCap: determining the diagnostic accuracy of colon capsule endoscopy compared with standard colonoscopy in patients at risk of colorectal disease – a study protocol
ColoCap: determining the diagnostic accuracy of colon capsule endoscopy compared with standard colonoscopy in patients at risk of colorectal disease – a study protocol Open
Background Lower gastrointestinal symptoms attributed to colorectal disease are common. Early diagnosis of serious colorectal disease such as colorectal cancer (CRC), precancerous growths (polyps) and inflammation is important to ensure th…
View article: PUrE Randomised Controlled Trial 2: Clinical and Cost Effectiveness of Flexible Ureterorenoscopy and Percutaneous Nephrolithotomy for Lower-pole Stones of 10–25 mm
PUrE Randomised Controlled Trial 2: Clinical and Cost Effectiveness of Flexible Ureterorenoscopy and Percutaneous Nephrolithotomy for Lower-pole Stones of 10–25 mm Open
Results from PUrE RCT 2 show that PCNL resulted in marginally better health status and a higher stone-free rate and was more cost-effective than FURS among patients with LPS of 10-25 mm. These outcomes are important for patient counselling…
View article: Text messaging with or without financial incentives versus a waitlist control for weight loss in men: cost-effectiveness analysis of the Game of Stones randomised controlled trial
Text messaging with or without financial incentives versus a waitlist control for weight loss in men: cost-effectiveness analysis of the Game of Stones randomised controlled trial Open
View article: The PUrE randomised controlled trial 1: Clinical and cost effectiveness of flexible ureterorenoscopy and extracorporeal shockwave lithotripsy for lower pole stones of ≤10 mm
The PUrE randomised controlled trial 1: Clinical and cost effectiveness of flexible ureterorenoscopy and extracorporeal shockwave lithotripsy for lower pole stones of ≤10 mm Open
PUrE RCT 1 found that there was no evidence of a difference in health status between FURS and ESWL for LPSs of ≤10 mm, with FURS leading to a higher stone-free rate. ESWL was more cost effective than FURS.
View article: Patient and healthcare professionals’ perception of weekly prophylactic catheter washout in adults living with long-term catheters: qualitative study of the CATHETER II trial
Patient and healthcare professionals’ perception of weekly prophylactic catheter washout in adults living with long-term catheters: qualitative study of the CATHETER II trial Open
Objectives To explore trial participants’ experience of long-term catheters (LTC), the acceptability of washout policies, their experience of the CATHETER II trial (a randomised controlled trial comparing the clinical effectiveness of vari…
View article: Invasive urodynamic investigations in the management of women with refractory overactive bladder symptoms (FUTURE) in the UK: a multicentre, superiority, parallel, open-label, randomised controlled trial
Invasive urodynamic investigations in the management of women with refractory overactive bladder symptoms (FUTURE) in the UK: a multicentre, superiority, parallel, open-label, randomised controlled trial Open
UK National Institute for Health and Care Research Health Technology Assessment Programme.
View article: Laparoscopic cholecystectomy <i>versus</i> conservative management for uncomplicated symptomatic gallstones: economic evaluation based on the C-GALL trial
Laparoscopic cholecystectomy <i>versus</i> conservative management for uncomplicated symptomatic gallstones: economic evaluation based on the C-GALL trial Open
View article: Secondary analysis of the Game of Stones trial of text messages with financial incentives for men with obesity
Secondary analysis of the Game of Stones trial of text messages with financial incentives for men with obesity Open
Objective To explore whether socio-economic, health and behavioural characteristics moderate effectiveness of a text message intervention with or without financial incentives versus a control group, and to examine differences in explorator…
View article: Men with long-term conditions in the Game of Stones text messaging and financial incentives trial: an exploratory mixed methods study
Men with long-term conditions in the Game of Stones text messaging and financial incentives trial: an exploratory mixed methods study Open
Men living with multiple long-term conditions and obesity are under-represented in behavioural weight management trials. Within an effective text messaging and financial incentives trial, our aim was to explore retention, secondary mental …
View article: Long-term Effects of Text Messages with Financial Incentives for Men with Obesity: Two-year Follow-up of the Game of Stones trial
Long-term Effects of Text Messages with Financial Incentives for Men with Obesity: Two-year Follow-up of the Game of Stones trial Open
Objectives To compare the difference in percentage weight change at 24 months following a 12-month text messaging with financial incentive intervention compared to a waiting list control group, and to compare the text messaging alone group…
View article: Mental health and weight loss in men: an exploratory mixed methods study of the Game of Stones trial
Mental health and weight loss in men: an exploratory mixed methods study of the Game of Stones trial Open
Objective Weight management interventions can affect mental health. Mental health can affect engagement with weight loss interventions or services. This study explored mental health and wellbeing outcomes, retention and participant experie…
View article: A feasibility randomized controlled trial of an individually delivered, peer support intervention to reduce the impact of psychosis stigma and discrimination for people with psychosis: the let's talk study
A feasibility randomized controlled trial of an individually delivered, peer support intervention to reduce the impact of psychosis stigma and discrimination for people with psychosis: the let's talk study Open
Background Stigma of mental health conditions hinders recovery and well-being. The Honest, Open, Proud (HOP) program shows promise in reducing stigma but there is uncertainty about the feasibility of a randomized trial to evaluate a peer-d…
View article: Enjoy Life LocallY (ELLY): feasibility study of a community co-designed incentive intervention to support healthy weight and wellbeing
Enjoy Life LocallY (ELLY): feasibility study of a community co-designed incentive intervention to support healthy weight and wellbeing Open
View article: 320 - Patient and health care professionals’ perception of weekly prophylactic catheter washout in adults living with long-term catheters: Qualitative Study of the CATHETER II Trial
320 - Patient and health care professionals’ perception of weekly prophylactic catheter washout in adults living with long-term catheters: Qualitative Study of the CATHETER II Trial Open
View article: 260 - CATHETER II, a randomised controlled trial comparing the clinical and cost effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long term catheters
260 - CATHETER II, a randomised controlled trial comparing the clinical and cost effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living with long term catheters Open
View article: Public perspective on potential treatment intervention harm in clinical trials—terminology and communication
Public perspective on potential treatment intervention harm in clinical trials—terminology and communication Open
View article: Assessment of depth of sedation using Bispectral Index™ monitoring in patients with severe traumatic brain injury in UK intensive care units
Assessment of depth of sedation using Bispectral Index™ monitoring in patients with severe traumatic brain injury in UK intensive care units Open
View article: Bisoprolol in Patients With Chronic Obstructive Pulmonary Disease at High Risk of Exacerbation
Bisoprolol in Patients With Chronic Obstructive Pulmonary Disease at High Risk of Exacerbation Open
Importance Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Observational studies report that β-blocker use may be associated with reduced risk of COPD exacerbations. However, a recent t…
View article: Text Messages With Financial Incentives for Men With Obesity
Text Messages With Financial Incentives for Men With Obesity Open
Importance Effective weight loss interventions are needed for men with obesity. Objective To determine whether an intervention that combined text messaging with financial incentives attained significant weight loss at the 12-month follow-u…
View article: Clinical and cost-effectiveness of percutaneous nephrolithotomy, flexible ureterorenoscopy and extracorporeal shockwave lithotripsy for lower pole stones: the PUrE RCTs
Clinical and cost-effectiveness of percutaneous nephrolithotomy, flexible ureterorenoscopy and extracorporeal shockwave lithotripsy for lower pole stones: the PUrE RCTs Open
Background Renal tract stone disease is common. The three intervention options are shockwave lithotripsy, flexible ureteroscopic stone treatment and keyhole surgery. Objectives To determine which of shockwave lithotripsy, flexible ureteros…
View article: SFX-01 in hospitalised patients with community-acquired pneumonia during the COVID-19 pandemic: a double-blind, randomised, placebo-controlled trial
SFX-01 in hospitalised patients with community-acquired pneumonia during the COVID-19 pandemic: a double-blind, randomised, placebo-controlled trial Open
Introduction Sulforaphane can induce the transcription factor, Nrf2, promoting antioxidant and anti-inflammatory responses. In this study, hospitalised patients with community-acquired pneumonia (CAP) were treated with stabilised synthetic…
View article: Evaluating Primary Treatment for People with Advanced Glaucoma
Evaluating Primary Treatment for People with Advanced Glaucoma Open
View article: Cost-Effectiveness of Text Messages with Loss-Framed Financial Incentives for Men with Obesity: The Game of Stone Trial
Cost-Effectiveness of Text Messages with Loss-Framed Financial Incentives for Men with Obesity: The Game of Stone Trial Open
View article: From opera buffa to opera seria: anniversaries of Royal College of Surgeons of England research initiatives
From opera buffa to opera seria: anniversaries of Royal College of Surgeons of England research initiatives Open
View article: Effectiveness of conservative management versus laparoscopic cholecystectomy in the prevention of recurrent symptoms and complications in adults with uncomplicated symptomatic gallstone disease (C-GALL trial): pragmatic, multicentre randomised controlled trial
Effectiveness of conservative management versus laparoscopic cholecystectomy in the prevention of recurrent symptoms and complications in adults with uncomplicated symptomatic gallstone disease (C-GALL trial): pragmatic, multicentre randomised controlled trial Open
Objective To assess the clinical and cost effectiveness of conservative management compared with laparoscopic cholecystectomy for the prevention of symptoms and complications in adults with uncomplicated symptomatic gallstone disease. Desi…
View article: Three‐year cost utility analysis of mini versus standard slings: A trial based economic evaluation
Three‐year cost utility analysis of mini versus standard slings: A trial based economic evaluation Open
Objective To report on the cost‐effectiveness of adjustable anchored single‐incision mini‐slings (mini‐slings) compared with tension‐free standard mid‐urethral slings (standard slings) in the surgical management of female stress urinary in…
View article: Emergency Department Resuscitative Endovascular Balloon Occlusion of the Aorta in Trauma Patients With Exsanguinating Hemorrhage
Emergency Department Resuscitative Endovascular Balloon Occlusion of the Aorta in Trauma Patients With Exsanguinating Hemorrhage Open
Importance Bleeding is the most common cause of preventable death after trauma. Objective To determine the effectiveness of resuscitative endovascular balloon occlusion of the aorta (REBOA) when used in the emergency department along with …
View article: Prevalence of urinary tract cancer in the Spanish cohort of the IDENTIFY study
Prevalence of urinary tract cancer in the Spanish cohort of the IDENTIFY study Open