Gráinne Murphy
YOU?
Author Swipe
View article: #2933 The use of patient reported outcomes in lupus nephritis clinical trials: a narrative review
#2933 The use of patient reported outcomes in lupus nephritis clinical trials: a narrative review Open
Background and Aims Patient-reported outcomes (PRO) were identified as a core systemic lupus erythematosus (SLE) outcome in 1999. A PRO is any report of a patient's health condition that comes directly from the patient without interpretati…
View article: Development of antibacterial coatings for endotracheal tubes with enhanced antibacterial release properties through combined antibiotic loading
Development of antibacterial coatings for endotracheal tubes with enhanced antibacterial release properties through combined antibiotic loading Open
Background Ventilator-associated pneumonia (VAP) is a significant cause of patient morbidity and mortality worldwide. This study describes a strategy to develop antibacterial hydrogel-based coating for endotracheal tubes, composed of 2-hyd…
View article: P047 Enteroviral infection in autoimmune rheumatic diseases treated with anti-CD20 monoclonal antibodies
P047 Enteroviral infection in autoimmune rheumatic diseases treated with anti-CD20 monoclonal antibodies Open
Background/Aims This case series describes two cases of CNS enteroviral infection in immunosuppressed patients with autoimmune rheumatic diseases (AIRDs). Enteroviral meningoencephalitis, a typically mild and self-limiting condition in imm…
View article: A prospective cohort study evaluating the role of quantifying sonographic inflammatory changes in GCA
A prospective cohort study evaluating the role of quantifying sonographic inflammatory changes in GCA Open
Objectives Vascular ultrasound (VUS) is a well-validated tool for diagnosing GCA [1]. The role of VUS in prognostication and disease-monitoring remains to be defined. Methods This study compares intima-media thickness (IMT), Halo Count (HC…
View article: CONTExT-RA: a cross-sectional study evaluating disease activity, quality of life and the socio-demographic profile of Irish patients with rheumatoid arthritis
CONTExT-RA: a cross-sectional study evaluating disease activity, quality of life and the socio-demographic profile of Irish patients with rheumatoid arthritis Open
Objectives CONTExT-RA is a cross-sectional, non-interventional multicentre study which enrolled patients diagnosed with RA and receiving DMARD treatment in a secondary care setting. The study evaluated disease control and associated diseas…
View article: 172 Using the early identification and management of delirium to optimise memory pathway referrals and resources
172 Using the early identification and management of delirium to optimise memory pathway referrals and resources Open
Background Priority actions within the National Dementia Strategy are to ensure early diagnosis of dementia and to develop appropriate referral pathways and interventions to support patients. One element is the consideration of referral to…
View article: POS0695 A PROSPECTIVE STUDY EVALUATING A PRE-TEST PROBABILITY SCORE IN THE DIAGNOSIS OF GIANT CELL ARTERITIS
POS0695 A PROSPECTIVE STUDY EVALUATING A PRE-TEST PROBABILITY SCORE IN THE DIAGNOSIS OF GIANT CELL ARTERITIS Open
Background Temporal Artery Ultrasound (TAUS) has been increasingly used in recent years to diagnose Giant Cell Arteritis (GCA) but has shown widely disparate results in studies to date [1-3]. A Pre-Test Probability Score (PTPS) has been de…
View article: Word learning in the context of semantic prior knowledge: evidence of interference from feature-based neighbours in children and adults
Word learning in the context of semantic prior knowledge: evidence of interference from feature-based neighbours in children and adults Open
The presence of phonological neighbours facilitates word-form learning, suggesting that prior phonological knowledge supports vocabulary acquisition. We tested whether prior semantic knowledge similarly benefits word learning by teaching 7…
View article: Evolution of ultrasound in giant cell arteritis
Evolution of ultrasound in giant cell arteritis Open
Ultrasound (US) is being increasingly used to diagnose Giant Cell Arteritis (GCA). The traditional diagnostic Gold Standard has been temporal artery biopsy (TAB), but this is expensive, invasive, has a false-negative rate as high as 60% an…
View article: P-432 Biologic use during conception and pregnancy and its impact on fetal and maternal outcomes: systematic review and meta-analysis
P-432 Biologic use during conception and pregnancy and its impact on fetal and maternal outcomes: systematic review and meta-analysis Open
Study question To determine pregnancy outcomes in women with chronic inflammatory disease exposed to biologics during conception and pregnancy. Summary answer Meta-analysis of 11172 pregnancies exposed to biologic medications show no evide…
View article: Word learning in the context of semantic prior knowledge: Evidence of interference from feature-based neighbours in children and adults
Word learning in the context of semantic prior knowledge: Evidence of interference from feature-based neighbours in children and adults Open
The presence of phonological neighbours facilitates word-form learning, suggesting that prior phonological knowledge supports vocabulary acquisition. We tested whether prior semantic knowledge similarly benefits word learning by teaching 7…
View article: Biologic therapies for systemic lupus erythematosus: where are we now?
Biologic therapies for systemic lupus erythematosus: where are we now? Open
Purpose of review Conventional approaches using hydroxychloroquine, corticosteroids and immunosuppressives have improved the prognosis for systemic lupus erythematosus (SLE) patients. Unfortunately, they have reached the limits of what the…
View article: Relationship Between Pain and Sedentary Behavior in Rheumatoid Arthritis Patients: A Cross‐Sectional Study
Relationship Between Pain and Sedentary Behavior in Rheumatoid Arthritis Patients: A Cross‐Sectional Study Open
Objective Despite the known benefits of physical activity, high numbers of individuals with rheumatoid arthritis (RA) remain physically inactive and sedentary. Little is known about the determinants of sedentary behavior (SB) in RA. This c…
View article: 36 Use of Biologics in Older Patients with Inflammatory Arthritis
36 Use of Biologics in Older Patients with Inflammatory Arthritis Open
Background Biologics are a key component of the treatment armamentarium for inflammatory arthritis (IA). Questions remain surrounding the prescription, efficacy and safety of biologics in the older population. This study aims to describe t…
View article: High Ankle Sprains in Professional Ice Hockey Players: Prognosis and Correlation Between Magnetic Resonance Imaging Patterns of Injury and Return to Play
High Ankle Sprains in Professional Ice Hockey Players: Prognosis and Correlation Between Magnetic Resonance Imaging Patterns of Injury and Return to Play Open
Background: Hockey players sustain a greater incidence of ankle syndesmosis injuries than other athletes. These injuries have a higher morbidity and more unpredictable recovery than lateral ankle sprains. Magnetic resonance imaging (MRI) h…
View article: 203 An Evaluation of Polypharmacy and Adverse Drug Events in Older Adults with Rheumatic Disease
203 An Evaluation of Polypharmacy and Adverse Drug Events in Older Adults with Rheumatic Disease Open
Background Polypharmacy among older adults is a well-documented problem. The practice has been associated with potentially inappropriate medications (PIMs, adverse drug events (ADEs) and hospitalisation. This retrospective cohort study aim…
View article: Investigating Idiopathic Inflammatory Myopathy; Initial Cross Speciality Experience with Use of the Extended Myositis Antibody Panel
Investigating Idiopathic Inflammatory Myopathy; Initial Cross Speciality Experience with Use of the Extended Myositis Antibody Panel Open
The discovery of unique autoantibodies has informed and altered our approach to the diagnosis and management of the inflammatory myopathies. This study reports the initial clinical experience of use of the Extended Myositis Antibody (EMA) …